Efficient one-step synthesis of diarylacetic acids by electrochemical direct carboxylation of diarylmethanol compounds in DMSO

• Hisanori Senboku and
• Mizuki Hayama

Beilstein J. Org. Chem. 2024, 20, 2392–2400, doi:10.3762/bjoc.20.203

• Pt cathode and a Mg anode in the presence of carbon dioxide induced reductive C(sp3)−O bond cleavage at the benzylic position in diarylmethanol compounds and subsequent fixation of carbon dioxide to produce diarylacetic acids in good yield. This protocol provides a novel and simple approach to

• though there was no electron-withdrawing group on the phenyl ring in the benzyl alcohols, electrochemical carboxylation of the benzyl alcohols in DMSO provided the corresponding phenylacetic acids in moderate yield by reductive C(sp3)–O bond cleavage followed by fixation of carbon dioxide at the benzylic

• used as substrate, selective C–O bond cleavage, followed by fixation of carbon dioxide, occurred at the benzylic C(sp3)–O bond rather than the C(sp2)–O bond on the phenyl ring to give the corresponding diphenylacetic acid 2h in 45% yield. Not only a secondary alcohol but also a tertiary alcohol was

Anion effect controlling the selectivity in the zinc-catalysed copolymerisation of CO₂ and cyclohexene oxide

• Sait Elmas,
• Muhammad Afzal Subhani,
• Walter Leitner and
• Thomas E. Müller

Beilstein J. Org. Chem. 2015, 11, 42–49, doi:10.3762/bjoc.11.7

• copolymerisation reaction. Keywords: anion effect; carbon dioxide; CO2 chemistry; copolymerisation; polyethercarbonate; zinc catalyst; Introduction The fixation of carbon dioxide (CO2) into polymers [1][2][3] provides highly promising options for the utilization of CO2 [4][5][6][7]. The copolymerisation of CO2

Electrocarboxylation: towards sustainable and efficient synthesis of valuable carboxylic acids

• Roman Matthessen,
• Jan Fransaer,
• Koen Binnemans and
• Dirk E. De Vos

Beilstein J. Org. Chem. 2014, 10, 2484–2500, doi:10.3762/bjoc.10.260

• and lead to a decrease in faradaic efficiency. Electrocarboxylation, the electrochemical fixation of carbon dioxide in organic chemicals, involves the electroreduction of carbon dioxide and/or an organic substrate. For olefins, alkynes, carbonyl compounds, imines and organic halides, this leads to the

• undivided cell [38]. From this point on most of the research in the field of CO2 fixation was focused on this type of setup. Electrocarboxylation of conjugated dienes The electrochemical fixation of carbon dioxide in 1,3-butadiene has been extensively investigated because of the importance of adipic acid