Controlled supramolecular assemblies of luminescent tridentate cyclometalated alkynylgold(III) amphiphiles in aqueous media

• Kelvin Sze-Yim Cai,
• Brian Boyan Liu and
• Franco King-Chi Leung

Beilstein J. Org. Chem. 2026, 22, 1097–1106, doi:10.3762/bjoc.22.88

• from disordered nanosheets to well-ordered nanoribbons upon the additions of multiple equivalents of counterion, enabling a tunable pathway for controlled supramolecular transformation. Keywords: amphiphiles; gold(III) complex; luminescence; self-assembly; supramolecular chemistry; Introduction

• luminescent soft materials can be established towards biomedical and biomaterial applications. Results and Discussion Design and synthesis of GA The gold amphiphile was designed with a tridentate C^N^C cyclometalated gold(III) complex core, which is functionalized with a σ-donating alkynyl ligand. A propargyl

• cyclometalated gold(III) complex 2 was synthesized and further reacted with compound 1 in the presence of triethylamine and a catalytic amount of copper iodide to afford the amphiphile precursor 3. The nucleophilic substitution of compound 3 with trimethylamine enabled to afford GA. The chemical structures of

The trans-influence in gold chemistry from a catalytic perspective

• Manfred Bochmann

Beilstein J. Org. Chem. 2026, 22, 838–856, doi:10.3762/bjoc.22.66

• intense blue on warming and appears to be the first case of a gold(III) complex emitting by a thermally activated delayed fluorescence (TADF) process, where excited singlet and triplet states are of comparable energy, which allows effective triplet harvesting and high quantum yields. Luminescence

• -complexes stabilised by C^N^C and C^N chelate ligands [28][29][30][31][32] and an example of a gold(III) complex targeting oestrogen-receptor positive (ER+) breast cancer cells [11][33][34][35][36]. Gold(III) C^C chelate complexes. Gold hydride complexes supported by tridentate pincer ligands and

Hypervalent iodine-mediated intramolecular alkene halocyclisation

• Charu Bansal,
• Oliver Ruggles,
• Albert C. Rowett and
• Alastair J. J. Lennox

Beilstein J. Org. Chem. 2024, 20, 3113–3133, doi:10.3762/bjoc.20.258

• instead proceeded with addition of dichloro(pyridine-2-carboxylato)gold(III) complex in combination with silver triflimide, AgNTf2. A range of β-fluoroazepanes 7 were successfully synthesised with high enantiomeric purity in good yields. A mechanism for the synthesis of β-fluorinated piperidines was

Pyridylidene ligand facilitates gold-catalyzed oxidative C–H arylation of heterocycles

• Kazuhiro Hata,
• Hideto Ito,
• Yasutomo Segawa and
• Kenichiro Itami

Beilstein J. Org. Chem. 2015, 11, 2737–2746, doi:10.3762/bjoc.11.295

• confirmed that the esterification of 2-iodobenzoic acid takes place to give 5 under the reaction conditions; 2-iodobenzoic acid was smoothly converted to 5 in chloroform/methanol solution at 65 °C. Transmetalation of gold(III) complex B with arylsilane 2 affords monoarylated gold(III) intermediate C. The

• and isolation of PyC-gold(III) complex To verify our hypothesis that PyC accelerates the gold(I)-to-gold(III) oxidation, we attempted the direct observation and the isolation of the PyC-gold(III) complex. First of all, the gold(III) complex AuCl3(PyC) was newly synthesized by treating AuCl(PyC) with

• coordinates to a gold center and promotes the gold(I)-to-gold(III) oxidation by stabilizing a gold(III) species without dissociation. An IPr-gold(III) complex is known to be stable, but the lower electron-donation ability of IPr than that of PyC seems to result in the inefficient oxidation of AuCl(IPr). DFT

The chemistry of amine radical cations produced by visible light photoredox catalysis

• Jie Hu,
• Jiang Wang,
• Theresa H. Nguyen and
• Nan Zheng

Beilstein J. Org. Chem. 2013, 9, 1977–2001, doi:10.3762/bjoc.9.234

• were realized with slower formation of the iminium ions. This was achieved by use of [Ru(bpy)3](PF6)2 in conjunction with a weak light source (5 W fluorescence bulb). The Che group synthesized a photoactive gold(III) complex that was shown to catalyze α-cyanation of N-aryltetrahydroisoquinolines [75

• ]. Very recently, Zhu and coworkers used an analogous gold(III) complex to catalyze the reactions similar to those reported by the Rueping group (Scheme 9) [76]. A 5 W blue LED was used as the light source. One advantage of using the gold complex over [Ru(bpy)3](PF6)2 is that long-chain aliphatic ketones