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Search for "organophosphorous" in Full Text gives 5 result(s) in Beilstein Journal of Organic Chemistry.

Recent advances in the electrochemical synthesis of organophosphorus compounds

  • Babak Kaboudin,
  • Milad Behroozi,
  • Sepideh Sadighi and
  • Fatemeh Asgharzadeh

Beilstein J. Org. Chem. 2025, 21, 770–797, doi:10.3762/bjoc.21.61

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  • efficiency of reactions [14][15][16][17][18][19][20][21]. Organophosphorous compounds are essential materials with broad applications in medicinal chemistry, synthesis, agriculture, as ligands, and intermediates to prepare complex compounds. Due to their importance, scientists have introduced many studies in
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Review
Published 16 Apr 2025

Catalysing (organo-)catalysis: Trends in the application of machine learning to enantioselective organocatalysis

  • Stefan P. Schmid,
  • Leon Schlosser,
  • Frank Glorius and
  • Kjell Jorner

Beilstein J. Org. Chem. 2024, 20, 2280–2304, doi:10.3762/bjoc.20.196

Graphical Abstract
  • and type II’ β-hairpin. Even though the latter was consistently lower in ground state energy (up to 6 kcal/mol for some catalysts), predictive models for enantioselectivity were found for both catalyst conformers in separate MLR models. For organophosphorous ligands of transition metal complexes, the
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Review
Published 10 Sep 2024

Efficient syntheses of climate relevant isoprene nitrates and (1R,5S)-(−)-myrtenol nitrate

  • Sean P. Bew,
  • Glyn D. Hiatt-Gipson,
  • Graham P. Mills and
  • Claire E. Reeves

Beilstein J. Org. Chem. 2016, 12, 1081–1095, doi:10.3762/bjoc.12.103

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  • all our efforts at generating 57 failed, affording instead highly coloured, complex mixtures (1H NMR) that were difficult to purify. Whilst researching alternative organophosphorous mediated C=C bond forming reactions that incorporated chloroacetone the synthesis of 3-methyl-4-chlorocrotonic ethyl
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Full Research Paper
Published 27 May 2016

Synthesis of isoprenoid bisphosphonate ethers through C–P bond formations: Potential inhibitors of geranylgeranyl diphosphate synthase

  • Xiang Zhou,
  • Jacqueline E. Reilly,
  • Kathleen A. Loerch,
  • Raymond J. Hohl and
  • David F. Wiemer

Beilstein J. Org. Chem. 2014, 10, 1645–1650, doi:10.3762/bjoc.10.171

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  • no activity against FDPS even at a 10 μM concentration. Keywords: bisphosphonate; isoprenoid biosynthesis; organophosphorous; phosphonate formation; Introduction Several enzymes of the isoprenoid biosynthesis pathways are the targets of widely prescribed drugs. For example, hydroxymethylglutaryl
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Published 18 Jul 2014

Group-assisted purification (GAP) chemistry for the synthesis of Velcade via asymmetric borylation of N-phosphinylimines

  • Jian-bo Xie,
  • Jian Luo,
  • Timothy R. Winn,
  • David B. Cordes and
  • Guigen Li

Beilstein J. Org. Chem. 2014, 10, 746–751, doi:10.3762/bjoc.10.69

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  • . Keywords: asymmetric borylation; GAP chemistry; organophosphorous; N-phosphinylimine; Velcade; Introduction The synthesis of chiral α-aminoboronic acids and their derivatives has attracted much attention in the organic and medicinal chemistry communities because of their importance for drug discovery and
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Letter
Published 31 Mar 2014
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