Efficient modification of peroxydisulfate oxidation reactions of nitrogen-containing heterocycles 6-methyluracil and pyridine

• Alfiya R. Gimadieva,
• Yuliya Z. Khazimullina,
• Aigiza A. Gilimkhanova and
• Akhat G. Mustafin

Beilstein J. Org. Chem. 2024, 20, 2599–2607, doi:10.3762/bjoc.20.219

• : oxidation; 6-methyluracil; peroxydisulfate; phthalocyanine catalysts; pyridine; Introduction The Elbs and Boyland–Sims peroxydisulfate oxidation reactions offer a convenient means of introducing the hydroxy function into phenols and aromatic amines [1]. The oxidation of phenol using peroxydisulfate was

• oxidation of nitrogen-containing heterocyclic compounds can be enhanced by the introduction of phthalocyanine catalysts or hydrogen peroxide into the reaction mixture. This approach has the potential to significantly increase the yield of the target compounds. Conclusion In conclusion, it is noted that we

• LLC, Russia), chloroform (reagent grade, JSC Khimreaktivsnab, Russia) and ethyl alcohol (reagent grade, LLC TD Khimmed, Russia) were used in this work. The phthalocyanine catalysts (Co, FeII, FeIII, Mn, Ni, and Zn phthalocyanines) were synthesized according to the known procedure [44] from