Beilstein J. Org. Chem.2024,20, 3134–3143, doi:10.3762/bjoc.20.259
-containing [2]staffane in the solid state.
Keywords: pentafluorosulfanylation; [1.1.1]propellane; radicalchainoligomerization; staffanes; strain-release; Introduction
In various radical additions of X–Y across [1.1.1]propellane (1), functionalized oligomers known as [n]staffanes – with n > 1, where n
substituted BCPs [25][26][27] or photochemical appendage of 1 onto an extant BCP [28][29][30][31] are relatively effective tactics for the selective assembly of certain [n]staffanes; the main caveat is that multiple synthetic steps are required. On the other hand, while a one-pot radicalchainoligomerization
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Graphical Abstract
Figure 1:
(Top) highlighting selectivity challenges in the synthesis of [n]staffanes using excess [1.1.1]prop...