Beilstein J. Org. Chem.2024,20, 3182–3190, doi:10.3762/bjoc.20.263
reactants. Finally, DFT calculations provided insights about the mechanism of this transformation, which strongly suggest that an SN2 reaction is operative.
Keywords: alkylation; DFT calculations; fluorine chemistry; hypervalent iodine; sulfoxonium ylide; sulphurylides; Introduction
Introducing fluorine
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Graphical Abstract
Figure 1:
Representative examples of fluorine containing, biologically active compounds.