Synthesis of 4-functionalized pyrazoles via oxidative thio- or selenocyanation mediated by PhICl₂ and NH₄SCN/KSeCN

• Jialiang Wu,
• Haofeng Shi,
• Xuemin Li,
• Jiaxin He,
• Chen Zhang,
• Fengxia Sun and
• Yunfei Du

Beilstein J. Org. Chem. 2024, 20, 1453–1461, doi:10.3762/bjoc.20.128

• ; thiocyanation; thiocyanogen chloride; Introduction Pyrazoles and their derivatives are an important class of five-membered heterocyclic compounds [1][2][3][4][5] that have drawn increasing attention from organic chemists, due to their potential biological and pharmaceutical properties including anti