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Search for "thiophene ring closure" in Full Text gives 1 result(s) in Beilstein Journal of Organic Chemistry.
Beilstein J. Org. Chem. 2025, 21, 2489–2497, doi:10.3762/bjoc.21.191
Graphical Abstract
Scheme 1: The synthetic routes to 3-hydroxy-substituted TT derivatives.
Scheme 2: The present retrosynthetic plan for constructing TT molecules.
Scheme 3: An attempt to nucleophilically substitute the NO2 group in ester 1.
Scheme 4: The reaction of ester 1 with potassium thioacetate.
Scheme 5: A probable mechanism for the formation of compounds 2 and 3.
Scheme 6: The synthesis of 3-(alkylthio)thiophene-2,5-dicarboxylates 4–6, yields, and scope of products. *Fro...
Scheme 7: The synthesis of TT derivatives, yields, and scope of products. Conditions: i) LiH (5 equiv), DMF, ...