Dual-functionalized architecture enables stable and tumor cell-specific SiO2NPs in complex biological fluids

Iris Renata Sousa Ribeiro, Raquel Frenedoso da Silva, Romênia Ramos Domingues, Adriana Franco Paes Leme and Mateus Borba Cardoso
Beilstein J. Nanotechnol. 2024, 15, 1238–1252. https://doi.org/10.3762/bjnano.15.100

Supporting Information

1H NMR spectrum for ZW compound; a scheme for functionalization of fluorescent SiO2NPs; a schematic representation of immunoprecipitation assay; high-resolution XPS spectrum for functionalized and non-functionalized SiO2NPs; analytical curve of fluorescence responses as a function of SiO2NPs concentration; analysis of protein corona formation after incubation of NPs in DMEM and human plasma (SDS-PAGE and LC-MS assays); hemolysis assay for functionalized and non-functionalized SiO2NPs; identification of the folate receptor in HaCat and KB cells; cell targeting assay using non-functionalized SiO2NPs and SiO2NPs-ZW-FO.

Supporting Information File 1: Additional figures and tables.
Format: PDF Size: 1.8 MB Download
Supporting Information File 2: Mass spectrometry proteomic data (raw and processed data, DMEM).
Format: XLSX Size: 891.8 KB Download
Supporting Information File 3: Mass spectrometry proteomic data (raw and processed data, plasma human).
Format: XLSX Size: 661.2 KB Download

Cite the Following Article

Dual-functionalized architecture enables stable and tumor cell-specific SiO2NPs in complex biological fluids
Iris Renata Sousa Ribeiro, Raquel Frenedoso da Silva, Romênia Ramos Domingues, Adriana Franco Paes Leme and Mateus Borba Cardoso
Beilstein J. Nanotechnol. 2024, 15, 1238–1252. https://doi.org/10.3762/bjnano.15.100

How to Cite

Sousa Ribeiro, I. R.; da Silva, R. F.; Domingues, R. R.; Leme, A. F. P.; Cardoso, M. B. Beilstein J. Nanotechnol. 2024, 15, 1238–1252. doi:10.3762/bjnano.15.100

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Presentation Graphic

Picture with graphical abstract, title and authors for social media postings and presentations.
Format: PNG Size: 11.2 MB Download
Other Beilstein-Institut Open Science Activities