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1 article(s) from Gupta, Govind

Graphene oxide–chloroquine conjugate induces DNA damage in A549 lung cancer cells through autophagy modulation

Braham Dutt Arya,
Sandeep Mittal,
Prachi Joshi,
Alok Kumar Pandey,
Jaime E. Ramirez-Vick,
Govind Gupta and
Surinder P. Singh

Beilstein J. Nanotechnol. 2025, 16, 316–332, doi:10.3762/bjnano.16.24

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Figure 1: Schematic representation for the process of chemical exfoliation and oxidation of graphite powder t...

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Figure 2: X-ray photoelectron spectroscopy analysis. C 1s core level spectra for GO (a), Chl (b), and GO–Chl ...

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Figure 3: Quantitative estimation of Chl binding onto GO nanosheets using UV–vis spectroscopy: (a) Optical de...

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Figure 4: Analysis of cellular internalization of GO–Chl nanoconjugates in A549 cells: (a) Transmission elect...

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Figure 5: Flow-cytometry-based propidium iodide uptake analysis of A549 cells exposed to GO–Chl: A dose-depen...

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Figure 6: Flow-cytometry-based cell cycle analysis of A549 cells exposed to GO–Chl. Different gates were used...

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Figure 7: Comet assay of GO–Chl nanoconjugates in A549 lung cancer cells: (a) digital image of the comet form...

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Figure 8: Accumulation of autophagosomes in GO–Chl-exposed A549 lung cancer cells: (a) Representative monodan...

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Figure 9: Mammalian GFP-LC3 transfection assay for autophagic flux analysis in A549 cells exposed to GO–Chl n...

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Figure 10: Western blot analysis of autophagy markers in cell lysates of GO–Chl-exposed A549 cells in a dose-(...

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Figure 11: Schematic showing the process of autophagy in mammalian cells, and the modulation of autophagy by c...

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Published 03 Mar 2025

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