Development of a mucoadhesive drug delivery system and its interaction with gastric cells

• Ahmet Baki Sahin,
• Serdar Karakurt and
• Deniz Sezlev Bilecen

Beilstein J. Nanotechnol. 2025, 16, 371–384, doi:10.3762/bjnano.16.28

• with gold (4 nm). STEM micrographs were obtained from one drop of nanoparticle suspension dripped on an ultrathin carbon-coated copper grid. Surface composition of nanoparticles For the analysis of various functional groups on the surface of nanoparticles before and after coating, attenuated total

Pulsed laser in liquid grafting of gold nanoparticle–carbon support composites

• Madeleine K. Wilsey,
• Teona Taseska,
• Qishen Lyu,
• Connor P. Cox and
• Astrid M. Müller

Beilstein J. Nanotechnol. 2025, 16, 349–361, doi:10.3762/bjnano.16.26

• , University of Rochester, Rochester, New York 14627, United States 10.3762/bjnano.16.26 Abstract We developed a novel pulsed laser-assisted process for the fabrication of advanced composites of nonequilibrium gold nanoparticles on carbon fiber paper supports. Our one-step process integrates the generation of

• nanoparticles with their surface attachment and solves longstanding nanoparticle adhesion and electrical contact issues. Irradiation of hydrophilic carbon fiber paper submerged in aqueous HAuCl4 solution by nanosecond laser pulses produced composites with uniform distribution of gold nanoparticles on carbon

• fibers, taking advantage of the high internal surface area of carbon fiber paper. The pulsed laser-grafted composites exhibited zero measurable charge transfer resistance between gold nanoparticles and the carbon support, leading to superior cathode performance over conventionally prepared electrodes for

Graphene oxide–chloroquine conjugate induces DNA damage in A549 lung cancer cells through autophagy modulation

• Braham Dutt Arya,
• Sandeep Mittal,
• Prachi Joshi,
• Alok Kumar Pandey,
• Jaime E. Ramirez-Vick,
• Govind Gupta and
• Surinder P. Singh

Beilstein J. Nanotechnol. 2025, 16, 316–332, doi:10.3762/bjnano.16.24

• equivalent of KMnO4 (added in two steps of 3 equiv each) were used relative to the graphite powder used. Chloroquine binds to the surface of graphene oxide nanosheets through noncovalent π–π interactions between the quinoline ring of Chl and the sp2 hybrid π-bonded carbon framework of graphene oxide. The

• sp2 carbon domain and structural disorders raised due to various factors, respectively [45][46]. Further, the presence of a well-defined D band in the Raman spectra of GO could be attributed to the chemical conversion of graphitic sp2 carbon into oxygen-rich functional groups such as C=O, C–OH, and C

• /IG ratio (0.882) is observed for the GO–Chl sample compared to that of GO (0.929). This indicates a possible conversion of the sp3 carbon to sp2 carbon due to the reducing environment imparted by the amino functionalities present on the Chl, which was also corroborated by FTIR data [47]. Furthermore

Enhancing mechanical properties of chitosan/PVA electrospun nanofibers: a comprehensive review

• Nur Areisman Mohd Salleh,
• Amalina Muhammad Afifi,
• Fathiah Mohamed Zuki and
• Hanna Sofia SalehHudin

Beilstein J. Nanotechnol. 2025, 16, 286–307, doi:10.3762/bjnano.16.22

• entanglement and promoting fiber formation [58]. A summary of the applications of chitosan/PVA nanofibers is provided in Table 2. PVA is a synthetic polymer widely utilized in various industries because of its versatile properties. Its water solubility allows for a wide range of applications, while its carbon

Emerging strategies in the sustainable removal of antibiotics using semiconductor-based photocatalysts

• Yunus Ahmed,
• Keya Rani Dutta,
• Parul Akhtar,
• Md. Arif Hossen,
• Md. Jahangir Alam,
• Obaid A. Alharbi,
• Hamad AlMohamadi and
• Abdul Wahab Mohammad

Beilstein J. Nanotechnol. 2025, 16, 264–285, doi:10.3762/bjnano.16.21

• , oxides of titanium, zinc, bismuth, and tungsten, as well as graphene, graphitic carbon nitride (g-C3N4), and their substitute materials are commonly synthesized and used as photocatalysts for the removal of antibiotics from contaminated sources. These materials are synthesized through a variety of

• or other transition metals through doping can potentially improve Bi2WO6 light absorption capabilities and increase the antibiotic degradation efficiency [98]. Some metal-doped bismuth photocatalysts and their antibiotic degradation efficiency are summarized below in Table 3. Graphitic carbon nitride

• -based materials Graphitic carbon nitride (g-C3N4) is a metal-free semiconductor material with distinct optical, electrical, structural, and physicochemical characteristics [99]. These properties make it well-suited for applications in energy and environmental fields. Because of its narrow bandgap of 2.7

Preferential enrichment and extraction of laser-synthesized nanoparticles in organic phases

• Theo Fromme,
• Maximilian L. Spiekermann,
• Florian Lehmann,
• Stephan Barcikowski,
• Thomas Seidensticker and
• Sven Reichenberger

Beilstein J. Nanotechnol. 2025, 16, 254–263, doi:10.3762/bjnano.16.20

• modify the nanomaterials in situ via chemical reactions of the nanoparticles with the molecules or solutes of the liquid. Particularly when organic solvents are used as liquids, photothermally induced C–C cleavage, addition or dehydrogenation reactions of the solvents, as well as (carbon

• system. The abundance of nanoparticles in PC or alcohol was found to correlate with the electrochemical reduction potential of the respective metal, where the noble metals were enriched within the more polar solvents. The polarity of the solvents (as function of the carbon chain length of the alcohol

• formed nanoparticles [1][2][3]. However, the formed nanoparticles also interact with the used liquid during the process; thus, chemical reactions such as oxidation [3][4][5][6] or carbon shell formation [7][8][9] occur depending on the solvent’s properties, allowing for alterations of the structural

Radiosensitizing properties of dual-functionalized carbon nanostructures loaded with temozolomide

• Radmila Milenkovska,
• Nikola Geskovski,
• Dushko Shalabalija,
• Ljubica Mihailova,
• Petre Makreski,
• Dushko Lukarski,
• Igor Stojkovski,
• Maja Simonoska Crcarevska and
• Kristina Mladenovska

Beilstein J. Nanotechnol. 2025, 16, 229–251, doi:10.3762/bjnano.16.18

• , temozolomide (TMZ), a drug used for the treatment of anaplastic astrocytoma and glioblastoma multiforme (GBM), was incorporated into multiwalled carbon nanotubes (MWCNTs) and a MWCNTs–graphene (MWCNTs-G) hybrid compound, covalently functionalized with polyethylene glycol (PEG) 6000 and folic acid (FA), with an

• -functionalized carbon nanostructures (CNs) were evaluated in vitro on a GBM cell line (U87MG), as well as their radiosensitizing properties after exposure of the pre-treated GBM cells to gamma radiation with a standard clinical dose for patients with GBM. All prepared formulations underwent biopharmaceutical and

• promotes more intense contact with the cells and rupture of cell membranes. Overall, the findings demonstrate the radiosensitizing properties of not only TMZ but also of CNs and point to a clinical benefit from combined treatment with carbon nanocarriers of TMZ and radiotherapy in GBM. Keywords: carbon

Synthesis and the impact of hydroxyapatite nanoparticles on the viability and activity of rhizobacteria

• Bedah Rupaedah,
• Indrika Novella,
• Atiek Rostika Noviyanti,
• Diana Rakhmawaty Eddy,
• Anna Safarrida,
• Abdul Hapid,
• Zhafira Amila Haqqa,
• Suryana Suryana,
• Irwan Kurnia and
• Fathiyah Inayatirrahmi

Beilstein J. Nanotechnol. 2025, 16, 216–228, doi:10.3762/bjnano.16.17

• . Furthermore, they require only small quantities for utilization [8]. Several types of nanoparticles have been employed as carriers for rhizobacteria inoculants, including silica nanoparticles [9], clay nanoparticles [8], carbon nanoparticles [10], zinc oxide nanoparticles [11], and calcium carbonate

• the elemental composition of the rhizobacteria-nHA comprising Ca, P, O, and C. Ca, P, and O constitute the components of the nHA carrier material, while C originates from the rhizobacteria. The percentage of carbon in the Pd-nHA sample is notably higher, reaching 59.04%, compared to the 46.14% of the

Recent advances in photothermal nanomaterials for ophthalmic applications

• Jiayuan Zhuang,
• Linhui Jia,
• Chenghao Li,
• Rui Yang,
• Jiapeng Wang,
• Wen-an Wang,
• Heng Zhou and
• Xiangxia Luo

Beilstein J. Nanotechnol. 2025, 16, 195–215, doi:10.3762/bjnano.16.16

• categorized into three distinct types based on their different photothermal conversion mechanisms, which arise from their unique electronic structures [23][24]. The types include metals exhibiting localized surface plasmon resonance (LSPR), carbon and polymer materials undergoing molecular thermal vibration

• biological tissues, thereby minimizing photothermal damage to non-pathological areas [54]. 2.2 Carbon and polymer materials Carbon and polymer materials primarily undergo photothermal conversion through a mechanism known as molecular thermal vibration. This process is initiated when the energy of incident

• heat (see below in Figure 2d) [57]. The presence of a high density of loosely bound electrons and the narrow energy level spacing of the π electrons endow carbon materials (such as graphene, carbon nanotubes, carbon quantum dots, and fullerenes) and polymer materials (like polydopamine, polyaniline

A review of metal-organic frameworks and polymers in mixed matrix membranes for CO₂ capture

• Charlotte Skjold Qvist Christensen,
• Nicholas Hansen,
• Mahboubeh Motadayen,
• Nina Lock,
• Martin Lahn Henriksen and
• Jonathan Quinson

Beilstein J. Nanotechnol. 2025, 16, 155–186, doi:10.3762/bjnano.16.14

Clays enhanced with niobium: potential in wastewater treatment and reuse as pigment with antibacterial activity

• Silvia Jaerger,
• Patricia Appelt,
• Mario Antônio Alves da Cunha,
• Fabián Ccahuana Ayma,
• Ricardo Schneider,
• Carla Bittencourt and
• Fauze Jacó Anaissi

Beilstein J. Nanotechnol. 2025, 16, 141–154, doi:10.3762/bjnano.16.13

• regeneration of the adsorbent. Various adsorbents including chitosan, cellulose, organophilic clays, kaolinite and montmorillonite clays, and activated carbon have been used for removing toxic compounds from polluted water [6]. Among these adsorbents, bentonite and smectite clays exhibit advantageous

TiO₂ immobilized on 2D mordenite: effect of hydrolysis conditions on structural, textural, and optical characteristics of the nanocomposites

• Marina G. Shelyapina,
• Rosario Isidro Yocupicio-Gaxiola,
• Gleb A. Valkovsky and
• Vitalii Petranovskii

Beilstein J. Nanotechnol. 2025, 16, 128–140, doi:10.3762/bjnano.16.12

• immobilization of TiO2 nanoparticles is of great importance. Many materials are considered as a possible support for immobilization, including porous ceramics [15], glass [16][17], porous carbon materials [18][19], mesoporous silica [20][21][22][23], and zeolites [24][25][26][27]. Recent studies have confirmed

• accuracy of the experiment). Therefore, this step is immediately followed by condensation: The final composition of the hydrolysis products of alkoxides of titanium roughly corresponds to TiO1.5(OR)·yROH, where y = 0.15–1.00 depending on the nature of the alcohol. The residual carbon during thermal

Comparison of organic and inorganic hole transport layers in double perovskite material-based solar cell

• Deepika K and
• Arjun Singh

Beilstein J. Nanotechnol. 2025, 16, 119–127, doi:10.3762/bjnano.16.11

• Karapinar [2] fabricated a dye-sensitized solar cell (DSSC) with selenium@activated carbon (Se@AC) composites as an alternative to the Pt counter electrode (CE) via chemical activation. The fabricated DSSC showed a power conversion efficiency (PCE) of 5.67%, an open-circuit voltage (VOC) of 0.648 V, a short

Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy

• Naths Grazia Sukubo,
• Paolo Bigini and
• Annalisa Morelli

Beilstein J. Nanotechnol. 2025, 16, 97–118, doi:10.3762/bjnano.16.10

• demonstrated by Ji and colleagues in a mouse model of carbon tetrachloride (CCl4)-induced fibrosis, where they inhibited the proliferation of fibroblasts [46]. An alternative to depletion is the inhibition of KCs through chloroquine, an antimalaria agent that inhibits macrophage-specific endocytosis, or

Modeling and simulation of carbon-nanocomposite-based gas sensors

• Roopa Hegde,
• Punya Prabha V,
• Shipra Upadhyay and
• Krishna S B

Beilstein J. Nanotechnol. 2025, 16, 90–96, doi:10.3762/bjnano.16.9

• Roopa Hegde Punya Prabha V Shipra Upadhyay Krishna S B Electronics and Communication Engineering, Ramaiah Institute of Technology, MSRIT Post, M S Ramaiah Nagar, MSR Nagar, Bengaluru, Karnataka 560054, India 10.3762/bjnano.16.9 Abstract This paper reports simulation of a carbon monoxide gas

• sensor using COMSOL Multiphysics whose active sensing material used is a carbon nanocomposite (i.e., 0.1 wt % of single-walled carbon nanotubes along with PEDOT:PSS (poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)) in an equal volume ratio of 1:1. Given the high cost associated with the

• development of these sensors, it becomes imperative to establish a mathematical model for economically predicting their behavior. The simulation using COMSOL Multiphysics is performed to obtain the surface coverage of the sensor by introducing carbon monoxide gas through a Gaussian pulse feed inlet at

Characterization of ZnO nanoparticles synthesized using probiotic Lactiplantibacillus plantarum GP258

• Prashantkumar Siddappa Chakra,
• Aishwarya Banakar,
• Shriram Narayan Puranik,
• Vishwas Kaveeshwar,
• C. R. Ravikumar and
• Devaraja Gayathri

Beilstein J. Nanotechnol. 2025, 16, 78–89, doi:10.3762/bjnano.16.8

• -electrode setup (carbon paste with ZnO NPs as the working electrode, platinum as the counter electrode, and Ag/AgCl as the reference electrode) in 0.1 M KCl. EIS measurements were carried out in a frequency range of 1 Hz to 1 MHz with a 5 mV AC amplitude, while CV studies were carried out on the same

Advanced atomic force microscopy techniques V

• Philipp Rahe,
• Ilko Bald,
• Nadine Hauptmann,
• Regina Hoffmann-Vogel,
• Harry Mönig and
• Michael Reichling

Beilstein J. Nanotechnol. 2025, 16, 54–56, doi:10.3762/bjnano.16.6

• different origins. The authors assign one type of defects to a possible defect in the Ir surface. The other type is identified as four missing carbon atoms corroborated by a higher reactivity with the tip. We thank all authors who contributed to this thematic issue and we are grateful to all reviewers for

Bioinspired nanofilament coatings for scale reduction on steel

• Siad Dahir Ali,
• Mette Heidemann Rasmussen,
• Jacopo Catalano,
• Christian Husum Frederiksen and
• Tobias Weidner

Beilstein J. Nanotechnol. 2025, 16, 25–34, doi:10.3762/bjnano.16.3

• surfaces. The elemental composition in Figure 4B shows the silicon emission expected for the SNF film, which is not present on the bare steel surface. Oxygen and carbon, additional components of the SNF coating, are also detected for the SNFs. At the same time, these elements are also observed on the bare

A nanocarrier containing carboxylic and histamine groups with dual action: acetylcholine hydrolysis and antidote atropine delivery

• Elina E. Mansurova,
• Andrey A. Maslennikov,
• Anna P. Lyubina,
• Alexandra D. Voloshina,
• Irek R. Nizameev,
• Marsil K. Kadirov,
• Anzhela A. Mikhailova,
• Polina V. Mikshina,
• Albina Y. Ziganshina and
• Igor S. Antipin

Beilstein J. Nanotechnol. 2025, 16, 11–24, doi:10.3762/bjnano.16.2

• electron microscopy (TEM) images were taken with a Libra 120 EFTEM (A Carl Zeiss SMT AG Company, Oberkochen, Carl Zeiss, Germany) at 100 kV. Samples were spread on a 300 mesh copper grid with a carbon/formvar support film. 1H and 13C NMR spectra were obtained using a Bruker Avance 600 spectrometer with an

Orientation-dependent photonic bandgaps in gold-dust weevil scales and their titania bioreplicates

• Norma Salvadores Farran,
• Limin Wang,
• Primoz Pirih and
• Bodo D. Wilts

Beilstein J. Nanotechnol. 2025, 16, 1–10, doi:10.3762/bjnano.16.1

• microscope (Zeiss, Oberkochen, Germany) using an in-lens secondary electron detector at 5 kV acceleration voltage. The scales and replicas were attached to an aluminum holder via a conductive carbon tape. These samples were coated with gold using a Sputter Coater 108 (Cressington Scientific Instruments

Mechanistic insights into endosomal escape by sodium oleate-modified liposomes

• Ebrahim Sadaqa,
• Satrialdi,
• Fransiska Kurniawan and
• Diky Mudhakir

Beilstein J. Nanotechnol. 2024, 15, 1667–1685, doi:10.3762/bjnano.15.131

Fabrication of hafnium-based nanoparticles and nanostructures using picosecond laser ablation

• Abhishek Das,
• Mangababu Akkanaboina,
• Jagannath Rathod,
• R. Sai Prasad Goud,
• Kanaka Ravi Kumar,
• Raghu C. Reddy,
• Ratheesh Ravendran,
• Katia Vutova,
• S. V. S. Nageswara Rao and
• Venugopal Rao Soma

Beilstein J. Nanotechnol. 2024, 15, 1639–1653, doi:10.3762/bjnano.15.129

• techniques The synthesised NPs were drop-cast on carbon-coated copper grids to record transmission electron microscopy (TEM) images and selected area electron diffraction (SAED) patterns using a FEI Tecnai G2 S-Twin operating at 200 kV. Further, these NPs were drop-cast on cleaned Si substrates, and their

• , we did not notice such a structure in the case of NPs fabricated in DW (Figure 4a). Shell-like structures in Figure 4b and Figure 4c are indicated with red arrows. These structures are multilayered carbon shells around the NPs. Similar formations were noticed in other studies where carbon-rich

• liquids were used [34][35][36]. The d-spacing of the carbon shells was determined from the zoomed images in Figure 5. It was estimated to be ≈0.34 nm, confirming the outer shell to be made of graphite [37][38][39]. A similar analysis was conducted on the nanofibre-like structures formed when Hf was

Electrochemical nanostructured CuBTC/FeBTC MOF composite sensor for enrofloxacin detection

• Thi Kim Ngan Nguyen,
• Tien Dat Doan,
• Huy Hieu Luu,
• Hoang Anh Nguyen,
• Thi Thu Ha Vu,
• Quang Hai Tran,
• Ha Tran Nguyen,
• Thanh Binh Dang,
• Thi Hai Yen Pham and
• Mai Ha Hoang

Beilstein J. Nanotechnol. 2024, 15, 1522–1535, doi:10.3762/bjnano.15.120

• /bjnano.15.120 Abstract A novel electrochemical sensor for the detection of enrofloxacin (ENR) in aqueous solutions has been developed using a carbon paste electrode modified with a mixture of metal-organic frameworks (MOFs) of CuBTC and FeBTC. These MOFs were successfully synthesized via a solvothermal

• sensors has some limitations associated with the low conductivity of MOFs. Therefore, the coupling with conducting materials, such as carbon-based materials, metal nanoparticles, and polymers, has been performed to enhance the electron charge transfer of MOFs [23][24]; single MOFs combined with carbon

• -based materials have been extensively studied [12][25][26][27][28]. A sensitive and simplified electrochemical sensor using a Cu3(BTC)2-modified carbon paste electrode for detecting 2,4-dichlorophenol was reported by Dong and his group [29]. Owing to the large specific surface area, high absorption

Integrating high-performance computing, machine learning, data management workflows, and infrastructures for multiscale simulations and nanomaterials technologies

• Fabio Le Piane,
• Mario Vozza,
• Matteo Baldoni and
• Francesco Mercuri

Beilstein J. Nanotechnol. 2024, 15, 1498–1521, doi:10.3762/bjnano.15.119

• suggests, silver, copper oxide, and titanium oxide [73]. ASCOT assists in the generation of high-quality digital twins of materials and the computation of relevant molecular descriptors. Nanotube Modeler is a software tool designed to create three-dimensional coordinates for various nanoscale carbon

Effect of radiation-induced vacancy saturation on the first-order phase transformation in nanoparticles: insights from a model

• Aram Shirinyan and
• Yuriy Bilogorodskyy

Beilstein J. Nanotechnol. 2024, 15, 1453–1472, doi:10.3762/bjnano.15.117

• comparison, in SiC, the energy of silicon vacancy migration is nearly 2.4 eV, and the energy of carbon vacancy migration is about 3.6 eV [42][43][44]. We focus on vacancy migration energies at the end of the paper and detail the findings. The surface energies σα and σβ of an iron-like nanoparticle are