Realizing active targeting in cancer nanomedicine with ultrasmall nanoparticles

• André F. Lima,
• Giselle Z. Justo and
• Alioscka A. Sousa

Beilstein J. Nanotechnol. 2024, 15, 1208–1226, doi:10.3762/bjnano.15.98

• , usNPs are therefore more biocompatible than larger NPs. However, it is important to emphasize that the physicochemical and biological properties of usNPs are highly sensitive to NP size and surface chemistry [64][67][68], and usNPs can still impact protein activity, biochemical pathways, and cellular

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

• Shakhzodjon Uzokboev,
• Khojimukhammad Akhmadbekov,
• Ra’no Nuritdinova,
• Salah M. Tawfik and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

Recent progress on field-effect transistor-based biosensors: device perspective

• Billel Smaani,
• Fares Nafa,
• Mohamed Salah Benlatrech,
• Ismahan Mahdi,
• Hamza Akroum,
• Mohamed walid Azizi,
• Khaled Harrar and
• Sayan Kanungo

Beilstein J. Nanotechnol. 2024, 15, 977–994, doi:10.3762/bjnano.15.80

• biosensors, with a low limit of quantification and detection. A real-time simulation of a highly sensitive specific antigen biosensor was also performed by Gao et al. [87] using silicon NW FET-based CMOS technology. In this work, both P- and N-type NW arrays were designed and incorporated into one chip using

• biomolecule species. Wenga et al. [90] designed a step-gate polysilicon FET-based biosensor for the detection of DNA. An emerging step-gate polycrystalline silicon NW FET-based biosensor was fabricated to enable highly sensitive electrical biosensing for DNA hybridization detection with a low-cost and simple

• fabrication process. The polysilicon NW FET (PSi-NW) is based on a silicon NW transistor with CMOS technology, implemented in highly sensitive biosensors for the detection of biological species. The PSi-NW is synthesized using the sidewall spacer formation technique and designed with a five-mask process with

Exploring surface charge dynamics: implications for AFM height measurements in 2D materials

• Mario Navarro-Rodriguez,
• Andres M. Somoza and
• Elisa Palacios-Lidon

Beilstein J. Nanotechnol. 2024, 15, 767–780, doi:10.3762/bjnano.15.64

• ratio. Moreover, their extensive surface exposure renders them highly sensitive to ambient and external influences, amplifying chemical reactivity [13] and bestowing attractive properties regarding electrochemical and catalytic reactions [14]. Furthermore, the ability to stack these materials

Stiffness calibration of qPlus sensors at low temperature through thermal noise measurements

• Laurent Nony,
• Sylvain Clair,
• Daniel Uehli,
• Aitziber Herrero,
• Jean-Marc Themlin,
• Andrea Campos,
• Franck Para,
• Alessandro Pioda and
• Christian Loppacher

Beilstein J. Nanotechnol. 2024, 15, 580–602, doi:10.3762/bjnano.15.50

• and enables the use of small oscillation amplitudes (A1 ≃ 50 pm), which render the probe highly sensitive to the short-range regime of interatomic forces. (ii) Their high quality factor (Q, ≃105 in a LT UHV system), which renders the PLL highly sensitive to the frequency tracking. (iii) Their

Superconducting spin valve effect in Co/Pb/Co heterostructures with insulating interlayers

• Andrey A. Kamashev,
• Nadir N. Garif’yanov,
• Aidar A. Validov,
• Vladislav Kataev,
• Alexander S. Osin,
• Yakov V. Fominov and
• Ilgiz A. Garifullin

Beilstein J. Nanotechnol. 2024, 15, 457–464, doi:10.3762/bjnano.15.41

• was measured by a Hall probe with an accuracy of ±0.3 Oe. The sample temperature was monitored using an Allen-Bradley thermometer that is highly sensitive in the temperature range of interest. The temperature measurement error was ±(5–6) mK below 3 K. The superconducting critical temperature Tc was

On the mechanism of piezoresistance in nanocrystalline graphite

• Sandeep Kumar,
• Simone Dehm and
• Ralph Krupke

Beilstein J. Nanotechnol. 2024, 15, 376–384, doi:10.3762/bjnano.15.34

• semiconducting grain boundaries can be considerably increased in the presence of strain. Hence, the asymmetric metallic grain boundaries undergo a metal–semiconductor transition in the presence of strain. This effect could open a way to utilize grain boundaries in graphene for fabricating highly sensitive

Ultrasensitive and ultrastretchable metal crack strain sensor based on helical polydimethylsiloxane

• Shangbi Chen,
• Dewen Liu,
• Weiwei Chen,
• Huajiang Chen,
• Jiawei Li and
• Jinfang Wang

Beilstein J. Nanotechnol. 2024, 15, 270–278, doi:10.3762/bjnano.15.25

• durability. These impressive attributes are attributed to the deliberate design of geometric structures and careful selection of connection types for the sensing materials, thereby presenting a novel approach to fabricating stretchable and highly sensitive crack-strain sensors. This work offers a universal

• -dimensional Ti3C2Tx MXene nanostacks [23]. The sensor exhibited a high GF of 772.6 when subjected to a strain range of 40–70%, owing to the presence of cracks induced in the MXene layer and carbon nanotubes (CNTs) acting as bridges. In a separate study, Xin et al. reported the fabrication of highly sensitive

New application of bimetallic Ag/Pt nanoplates in a colorimetric biosensor for specific detection of E. coli in water

• Azam Bagheri Pebdeni,
• Mohammad N. AL-Baiati and
• Morteza Hosseini

Beilstein J. Nanotechnol. 2024, 15, 95–103, doi:10.3762/bjnano.15.9

• popular and appealing since the presence of a specific pathogen can be easily observed by a simple change in color, which can be distinguished easily with the naked eye eliminating any use of expensive and complex types of equipment [29][30][31]. In this research, we provide a novel and highly sensitive

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

• Elangovan Sarathkumar,
• Rajasekharan S. Anjana and
• Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

• factor of almost 256 (Figure 7D). This observation underscores the importance of optimizing GNP size for maximizing sensitivity while mitigating potential drawbacks. This finding opens new possibilities for the highly sensitive and quantitative detection using LFAs, enhancing the applicability in various

• to functionalize with targeting agents such as antibodies and aptamers for LFAs. Therefore, photothermal LFAs are believed to play a significant role in the development of highly sensitive LFAs and other POCT devices. Schematic representation of photothermal LFA (Figure 1 was reprinted from [27

Silver-based SERS substrates fabricated using a 3D printed microfluidic device

• Phommachith Sonexai,
• Minh Van Nguyen,
• Bui The Huy and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2023, 14, 793–803, doi:10.3762/bjnano.14.65

• tool for detecting ultralow concentrations of chemical compounds and biomolecules. We present a reproducible method for producing Ag nanoparticles that can be used to create highly sensitive SERS substrates. A microfluidic device was employed to confine the precursor reagents within the droplets

• [40][41][42]. Silicon nanostructures with high specific areas are especially popular because they have no fluorescence properties. In this work, we report on the synthesis of a highly sensitive SERS substrate for detecting rhodamine B (RhB) and melamine (MLM) and on the analytical properties of the

Humidity-dependent electrical performance of CuO nanowire networks studied by electrochemical impedance spectroscopy

• Jelena Kosmaca,
• Juris Katkevics,
• Jana Andzane,
• Raitis Sondors,
• Liga Jasulaneca,
• Raimonds Meija,
• Kiryl Niherysh,
• Yelyzaveta Rublova and
• Donats Erts

Beilstein J. Nanotechnol. 2023, 14, 683–691, doi:10.3762/bjnano.14.54

• ]. Copper oxide (CuO) nanowires are excellent candidates for applications in such devices owing to the inexpensive, simple and scalable bottom-up synthesis, and robust physical properties [7][8][9]. A high specific surface area of nanowires and a p-type semiconductor structure are suggested for highly

• sensitive and fast responding nanowire-based gas sensors for the detection of CO, C2H5OH, H2S, and NO2 [10][11][12][13][14]. Unusually strong space-charge-limited currents observed in individual CuO nanowires [15] in combination with the mechanical strength [9][16] motivate their application as durable

SERS performance of GaN/Ag substrates fabricated by Ag coating of GaN platforms

• Magdalena A. Zając,
• Bogusław Budner,
• Malwina Liszewska,
• Bartosz Bartosewicz,
• Łukasz Gutowski,
• Jan L. Weyher and
• Bartłomiej J. Jankiewicz

Beilstein J. Nanotechnol. 2023, 14, 552–564, doi:10.3762/bjnano.14.46

• : GaN/Ag; magnetron sputtering; nanofabrication; pulsed laser deposition; SERS substrates; surface-enhanced Raman spectroscopy (SERS); Introduction Surface-enhanced Raman spectroscopy (SERS) is a highly sensitive and specific technique with multiplexing capabilities [1][2][3][4]. It is considered for

Carbon nanotube-cellulose ink for rapid solvent identification

• Tiago Amarante,
• Thiago H. R. Cunha,
• Claudio Laudares,
• Ana P. M. Barboza,
• Ana Carolina dos Santos,
• Cíntia L. Pereira,
• Vinicius Ornelas,
• Bernardo R. A. Neves,
• André S. Ferlauto and
• Rodrigo G. Lacerda

Beilstein J. Nanotechnol. 2023, 14, 535–543, doi:10.3762/bjnano.14.44

• sensor based on a carbon nanotube–cellulose ink that proves to be highly sensitive to various solvents and water with different impurity levels and can detect glycerin in water down to the 10–100 ppm range. We provide insights into the liquid detection mechanism, combining the well-known swelling

Characterisation of a micrometer-scale active plasmonic element by means of complementary computational and experimental methods

• Ciarán Barron,
• Giulia Di Fazio,
• Samuel Kenny,
• Silas O’Toole,
• Robin O’Reilly and
• Dominic Zerulla

Beilstein J. Nanotechnol. 2023, 14, 110–122, doi:10.3762/bjnano.14.12

• changes in the far-field reflectivity resulting from Joule heating. A clear modulation of the materials’ optical constants can be inferred from the changed reflectivity, which is highly sensitive and dependent on the input current. The changed electrical permittivity of the active element is due to Joule

• ) investigating the changes in the reflectivity induced by a modulated electric current. The acquisition of a surface plasmon resonance (SPR) curve is a common method to characterise a plasmonic far-field response [31] which is highly sensitive to small changes in the refractive index of the metal and dielectric

• -component signal of the lock-in amplifier, which originates from the changes in the temperature and is highly sensitive to a modification of the systems morphology with a fixed phase relationship. As the temperature is modulated, these alterations occur in tandem with the driving frequency. The increased

Combining physical vapor deposition structuration with dealloying for the creation of a highly efficient SERS platform

• Adrien Chauvin,
• Walter Puglisi,
• Damien Thiry,
• Cristina Satriano,
• Rony Snyders and
• Carla Bittencourt

Beilstein J. Nanotechnol. 2023, 14, 83–94, doi:10.3762/bjnano.14.10

• of the surface of the film was probed by XPS. The SERS properties of a structure are driven by the presence of ‘hot spots’. These are highly sensitive to the composition of the surface since the presence of impurities can hinder the SERS properties [30]. The XPS composition of the surface of the

Two-step single-reactor synthesis of oleic acid- or undecylenic acid-stabilized magnetic nanoparticles by thermal decomposition

• Mykhailo Nahorniak,
• Pamela Pasetto,
• Jean-Marc Greneche,
• Volodymyr Samaryk,
• Sandy Auguste,
• Anthony Rousseau,
• Nataliya Nosova and
• Serhii Varvarenko

Beilstein J. Nanotechnol. 2023, 14, 11–22, doi:10.3762/bjnano.14.2

• technique is highly sensitive to the valence state of Fe species and thus enables the identification of magnetite and maghemite and the estimation of their respective proportions. Measurements were performed in a transmission geometry with a 925 MBq γ-source of 57Co/Rh mounted using a conventional constant

Rapid and sensitive detection of box turtles using an electrochemical DNA biosensor based on a gold/graphene nanocomposite

• Abu Hashem,
• M. A. Motalib Hossain,
• Ab Rahman Marlinda,
• Mohammad Al Mamun,
• Khanom Simarani and
• Mohd Rafie Johan

Beilstein J. Nanotechnol. 2022, 13, 1458–1472, doi:10.3762/bjnano.13.120

• thermodynamically more stable than longer ones [27] and choosing a shorter target is favourable since it can withstand decomposition states [28]. To ameliorate these limitations and in order to rapidly verify the products, low-cost, highly sensitive, miniaturised, easily and onsite-applicable [29], health- and

Recent advances in green carbon dots (2015–2022): synthesis, metal ion sensing, and biological applications

• Aisha Kanwal,
• Naheed Bibi,
• Sajjad Hyder,
• Arif Muhammad,
• Hao Ren,
• Jiangtao Liu and
• Zhongli Lei

Beilstein J. Nanotechnol. 2022, 13, 1068–1107, doi:10.3762/bjnano.13.93

Efficiency of electron cooling in cold-electron bolometers with traps

• Dmitrii A. Pimanov,
• Vladimir A. Frost,
• Anton V. Blagodatkin,
• Anna V. Gordeeva,
• Andrey L. Pankratov and
• Leonid S. Kuzmin

Beilstein J. Nanotechnol. 2022, 13, 896–901, doi:10.3762/bjnano.13.80

• , Gothenburg, SE-412 96, Sweden Institute for Physics of Microstructures of the Russian Academy of Sciences, GSP-105, Nizhny Novgorod, 603950, Russia 10.3762/bjnano.13.80 Abstract Electron on-chip cooling from the base temperature of 300 mK is very important for highly sensitive detectors operating in space

• due to thinner tunneling barriers with higher quality. Conclusion Electron cooling is very important for highly sensitive measurements. At modern space applications, it may be the only reliable method to cool down the detector in 3He cryostats to achieve better sensitivity. Cold-electron bolometers

DNA aptamer selection and construction of an aptasensor based on graphene FETs for Zika virus NS1 protein detection

• Nathalie B. F. Almeida,
• Thiago A. S. L. Sousa,
• Viviane C. F. Santos,
• Camila M. S. Lacerda,
• Thais G. Silva,
• Rafaella F. Q. Grenfell,
• Flavio Plentz and
• Antero S. R. Andrade

Beilstein J. Nanotechnol. 2022, 13, 873–881, doi:10.3762/bjnano.13.78

• proteins of the four DENV serotypes and YFV. These attributes make ZIKV60 aptamer superior to other ZIKV NS1 aptamers reported so far. In addition, we validated the combination of ZIKV60 aptamer with FET devices based on graphene as a platform to assist the construction of highly sensitive aptasensors for

Modeling a multiple-chain emeraldine gas sensor for NH₃ and NO₂ detection

• Hana Sustkova and
• Jan Voves

Beilstein J. Nanotechnol. 2022, 13, 721–729, doi:10.3762/bjnano.13.64

• gradient approximated (GGA) Perdew–Burke–Ernzerhof (PBE) exchange–correlation functional was used. Guo et al. [5] investigated the graphene/polyaniline adsorption energy of NH3, CO, NO, and H2 using DFT and molecular dynamics computations. From this, graphene/PANI is highly sensitive to NH3 in comparison

Detection and imaging of Hg(II) in vivo using glutathione-functionalized gold nanoparticles

• Gufeng Li,
• Shaoqing Li,
• Rui Wang,
• Min Yang,
• Lizhu Zhang,
• Yanli Zhang,
• Wenrong Yang and
• Hongbin Wang

Beilstein J. Nanotechnol. 2022, 13, 549–559, doi:10.3762/bjnano.13.46

• GNPs-GSH-Rh6G2 In order to fabricate a robust and highly sensitive fluorescent probe, we optimized the synthesis conditions of GNPs-GSH-Rh6G2 including the molar ratio between GSH and Rh6G2 and the concentrations of GNPs and GSH. It was reported that the amino group in the GSH molecule and the aldehyde

Polarity in cuticular ridge development and insect attachment on leaf surfaces of Schismatoglottis calyptrata (Araceae)

• Venkata A. Surapaneni,
• Tobias Aust,
• Thomas Speck and
• Marc Thielen

Beilstein J. Nanotechnol. 2021, 12, 1326–1338, doi:10.3762/bjnano.12.98

• Surapaneni and co-workers [23]. A highly sensitive force transducer (FORT 25, force range: 0–0.25 N, World Precision Instruments Inc., Sarasota, USA) was used to measure maximum walking frictional forces of insects on the leaf surfaces. The elytra of each beetle was attached to the force transducer using a

Modification of a SERS-active Ag surface to promote adsorption of charged analytes: effect of Cu²⁺ ions

• Bahdan V. Ranishenka,
• Andrei Yu. Panarin,
• Irina A. Chelnokova,
• Sergei N. Terekhov,
• Peter Mojzes and
• Vadim V. Shmanai

Beilstein J. Nanotechnol. 2021, 12, 902–912, doi:10.3762/bjnano.12.67

• of metallic NP arrays with controllable parameters such as size, shape, interparticle distance, and ordering degree [5][6][7][8][9][10][11][12], with a focus on plasmonic structures with a high density of “hot spots”. Due to the progress in nanotechnology, a large number of highly sensitive SERS