Serum heat inactivation diminishes ApoE-mediated uptake of D-Lin-MC3-DMA lipid nanoparticles

• Demian van Straten,
• Luuk van de Schepop,
• Rowan Frunt,
• Pieter Vader and
• Raymond M. Schiffelers

Beilstein J. Nanotechnol. 2025, 16, 740–748, doi:10.3762/bjnano.16.57

• molar ratio of 50:38.5:10:1.5 and a final lipid concentration of 10 mM. siRNA was diluted in an acetate buffer (25 mM, pH 4.0) to a final concentration of 3.3 µM for MC3 LNPs and 12.33 µM for C12 LNPs. For fluorescent LNPs, siRNA and siRNA-AF647 were mixed 2:1 v/v. For MC3 LNPs the Nanoassemblr was set

Synthesis of a multicomponent cellulose-based adsorbent for tetracycline removal from aquaculture water

• Uyen Bao Tran,
• Ngoc Thanh Vo-Tran,
• Khai The Truong,
• Dat Anh Nguyen,
• Quang Nhat Tran,
• Huu-Quang Nguyen,
• Jaebeom Lee and
• Hai Son Truong-Lam

Beilstein J. Nanotechnol. 2025, 16, 728–739, doi:10.3762/bjnano.16.56

• concentration of 60 mg·L–1 at pH 6–7, reaching equilibrium after 12 h. The surface characteristics and structural properties of PGC were determined using various material characterization techniques, including FTIR, SEM, EDX, and BET. Verification experiments under optimal conditions confirmed that the

• high porosity and a large specific surface area, have demonstrated adsorption efficiency across a wide pH range [17]. Although previous studies have offered valuable insights, further research is needed to optimize the structural and compositional properties of materials to improve their performance

• characteristics and morphology of the synthesized adsorbent. Additionally, the study examines the adsorption mechanism of TC on the material’s surface and evaluates the effects of pH value, adsorbent dosage, and matrix composition. As a biodegradable and easily recoverable material derived from natural cellulose

Efficiency of single-pulse laser fragmentation of organic nutraceutical dispersions in a circular jet flow-through reactor

• Tina Friedenauer,
• Maximilian Spellauge,
• Alexander Sommereyns,
• Verena Labenski,
• Tuba Esatbeyoglu,
• Christoph Rehbock,
• Heinz P. Huber and
• Stephan Barcikowski

Beilstein J. Nanotechnol. 2025, 16, 711–727, doi:10.3762/bjnano.16.55

• −1 solution of potassium dihydrogen phosphate previously adjusted to pH 2.0 with phosphoric acid (A) and acetonitrile (B). The initial concentration of mobile phase B is increased from 30% to 70% within the time interval from 0 to 8 min, then further increased to 90%; this concentration is maintained

Colloidal few layered graphene–tannic acid preserves the biocompatibility of periodontal ligament cells

• Teissir Ben Ammar,
• Naji Kharouf,
• Dominique Vautier,
• Housseinou Ba,
• Nivedita Sudheer,
• Philippe Lavalle and
• Vincent Ball

Beilstein J. Nanotechnol. 2025, 16, 664–677, doi:10.3762/bjnano.16.51

• diameter glass coverslips (CML, France) in a 24-well plate and exposed to FLG–TA concentrations ranging from 1 to 200 µg·mL−1. Adherent cells were washed twice with PBS and fixed in 2.5% glutaraldehyde (Euromedex, France) in 0.05 M sodium cacodylate buffer (Euromedex, France) at pH 7.4 for 2 h. Cells were

Aprepitant-loaded solid lipid nanoparticles: a novel approach to enhance oral bioavailability

• Mazhar Hussain,
• Muhammad Farooq,
• Muhammad Asad Saeed,
• Muhammad Ijaz,
• Sherjeel Adnan,
• Zeeshan Masood,
• Muhammad Waqas,
• Wafa Ishaq and
• Nabeela Ameer

Beilstein J. Nanotechnol. 2025, 16, 652–663, doi:10.3762/bjnano.16.50

• microscopy (SEM), X-ray diffraction (XRD), differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA), in vitro drug release in 0.1 M HCl (pH 1.2) and phosphate-buffered saline (PBS, pH 7.4), and pharmacokinetic studies. The optimal formulation (APT-CD-NP4) containing the highest

• concentration of β-CD showed the highest drug solubility (93.50% ± 3.73%) in PBS (pH 7.4) and drug content (96.75% ± 0.24%); particle size, zeta potential, and polydispersity index of APT-CD-NP4 were 121.1 ± 0.72 nm, −18.8 ± 0.94 mV, and 0.15 ± 0.35, respectively. SEM analysis showed that APT was converted from

• release (98.89% ± 4.11%) in PBS (pH 7.4) and followed the Higuchi release model (with exponent n = 0.542), indicating non-Fickian diffusion (anomalous transport). The maximum concentration of drug in plasma and the bioavailability of optimal formulation APT-CD-NP4 were higher than those of pure APT

A formulation containing Cymbopogon flexuosus essential oil: improvement of biochemical parameters and oxidative stress in diabetic rats

• Ailton Santos Sena-Júnior,
• Cleverton Nascimento Santana Andrade,
• Pedro Henrique Macedo Moura,
• Jocsã Hémany Cândido dos Santos,
• Cauãn Torres Trancoso,
• Eloia Emanuelly Dias Silva,
• Deise Maria Rego Rodrigues Silva,
• Ênio Pereira Telles,
• Luiz André Santos Silva,
• Isabella Lima Dantas Teles,
• Sara Fernanda Mota de Almeida,
• Daniel Alves de Souza,
• Jileno Ferreira Santos,
• Felipe José Aidar Martins,
• Ana Mara de Oliveira e Silva,
• Sandra Lauton-Santos,
• Guilherme Rodolfo Souza de Araujo,
• Cristiane Bani Correa,
• Rogéria De Souza Nunes,
• Lysandro Pinto Borges and
• Ana Amélia Moreira Lira

Beilstein J. Nanotechnol. 2025, 16, 617–636, doi:10.3762/bjnano.16.48

• obtained after consulting the corresponding pseudoternary phase diagram and showed stability, isotropy, Newtonian behavior, nanometric size (15.2 nm), and pH 4.2. Both EOCF and the ME showed high antioxidant activity, but the ME resulted in greater antioxidant activity, potentiating the activity of

• diagram Various surfactants in different combinations were tested to obtain the ME. In general, non-ionic surfactants are most commonly used because they have a low critical micelle concentration, low toxicity, and greater stability to changes in pH and charge when compared to other classes of surfactants

• ][27], improving patient acceptance [28]. The pH value is also capable of inducing changes in stability and chemical phenomena, such as deterioration and oxidation of compounds and bacterial growth, and is a precise and specific measure for quality control of the formulation. The pH found for M7-EOCF

Functionalized gold nanoflowers on carbon screen-printed electrodes: an electrochemical platform for biosensing hemagglutinin protein of influenza A H1N1 virus

• Carlos Enrique Torres-Méndez,
• Sharmilee Nandi,
• Klara Martinovic,
• Patrizia Kühne,
• Yifan Liu,
• Sam Taylor,
• Maria Lysandrou,
• Maria Ines Berrojo Romeyro Mascarenhas,
• Viktoria Langwallner,
• Javier Enrique Sebastián Alonso,
• Ivana Jovanovic,
• Maike Lüftner,
• Georgia-Vasiliki Gkountana,
• David Bern,
• Abdul-Raouf Atif,
• Ehsan Manouchehri Doulabi,
• Gemma Mestres and
• Masood Kamali-Moghaddam

Beilstein J. Nanotechnol. 2025, 16, 540–550, doi:10.3762/bjnano.16.42

• , potassium chloride, potassium hexacyanoferrate(II) trihydrate, potassium hexacyanoferrate(III), N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC), N-hydroxy succinimide (NHS), phosphate-buffered saline pH 7.4 (PBS), and bovine serum albumin (BSA) were all purchased from Sigma-Aldrich

• in a 1.5 mL Eppendorf vial by adding 100 μL of 38 μg/mL mABs solution in PBS, 100 μL of 10 mM EDC aqueous solution, and 100 μL of 10 mM NHS aqueous solution. The pH of the mixture was 6.5 as determined by litmus paper. Then, 10 μL of the mixture was added on top of the 4-ATP/AuNFs/CSPE as working

Synthetic-polymer-assisted antisense oligonucleotide delivery: targeted approaches for precision disease treatment

• Ana Cubillo Alvarez,
• Dylan Maguire and
• Ruairí P. Brannigan

Beilstein J. Nanotechnol. 2025, 16, 435–463, doi:10.3762/bjnano.16.34

• delivery in tumour therapy. Poly(ʟ-glutamic acid). Poly(ʟ-glutamic acid) (PLG) is a biodegradable, water-soluble synthetic polymer composed of repeating units of the amino acid ʟ-glutamic acid. Owing to the presence of the carboxyl side chains, PLG is anionic under physiological conditions (pH ≈ 7.4). This

Quantification of lead through rod-shaped silver-doped zinc oxide nanoparticles using an electrochemical approach

• Ravinder Lamba,
• Gaurav Bhanjana,
• Neeraj Dilbaghi,
• Vivek Gupta and
• Sandeep Kumar

Beilstein J. Nanotechnol. 2025, 16, 422–434, doi:10.3762/bjnano.16.33

• presents the comparison of this work with other similar works. The fabricated sensor showed a slightly higher limit of detection (LOD) value, which is due to the use of PBS and the higher impedance of the electrode. An acidic pH provides better sensitivity, but it also brings health and safety issues

• , environmental impact, can cause electrode corrosion, enhances interference, and is incompatible with real-life or biological samples. Therefore, PBS with pH 7 has been used for electrochemical studies since it provides a stable pH, which is crucial for maintaining consistent electrochemical conditions during

• zinc nitrate hexahydrate solution. The resulting solution was stirred for approximately 10 min at room temperature. After the reaction time, a 1 M potassium hydroxide (KOH) solution was gradually added drop by drop. This step adjusted the pH of the mixture to 10. Then the mixture underwent further

Engineered PEG–PCL nanoparticles enable sensitive and selective detection of sodium dodecyl sulfate: a qualitative and quantitative analysis

• Soni Prajapati and
• Ranjana Singh

Beilstein J. Nanotechnol. 2025, 16, 385–396, doi:10.3762/bjnano.16.29

• , UK). Dried 10 mg/mL PEG–PCL NPs were dissolved in PBS and sonicated for 30 min. The sonicated sample was taken in a cuvette for measurement. The sample pH was in the range of 7.2–7.4. Separate cuvettes (DTS1072 and DTS0012) were used to measure the surface charge and average size of the nanoparticles

Development of a mucoadhesive drug delivery system and its interaction with gastric cells

• Ahmet Baki Sahin,
• Serdar Karakurt and
• Deniz Sezlev Bilecen

Beilstein J. Nanotechnol. 2025, 16, 371–384, doi:10.3762/bjnano.16.28

• positive charge. A peptide, as a model drug, was loaded onto the nanoparticles with an encapsulation efficiency of 58%. The release of the model drug from the delivery system was pH-independent and lasted for 7 days. The periodic acid–Schiff stain assay indicated 69% mucin interaction for the nanoparticles

• systems because of their ability to form gel-like structures in the presence of divalent cations such as Ca2+. Despite the advantages of alginate polymer such as its biodegradability, biocompatibility, and gelation ability, its instability, fast wettability, and rapid release at high pH result in the

• , effective encapsulation, pH-responsive release, and enhanced stability. Eudragit RS 100 is a copolymer of ethyl acrylate, methyl methacrylate, and a low proportion of methacrylic acid ester with quaternary ammonium groups. It is known for its mucoadhesive properties [16], which are independent of the site

Pulsed laser in liquid grafting of gold nanoparticle–carbon support composites

• Madeleine K. Wilsey,
• Teona Taseska,
• Qishen Lyu,
• Connor P. Cox and
• Astrid M. Müller

Beilstein J. Nanotechnol. 2025, 16, 349–361, doi:10.3762/bjnano.16.26

• pulsed laser-grafted gold nanoparticle–carbon fiber paper composite would lead to enhanced electrocatalytic performance. Therefore, we applied the laser-grafted gold nanoparticle–carbon fiber paper composites as cathodes for electrocatalytic bicarbonate reduction in aqueous 0.5 M KHCO3, pH 8.3

• (2H2O + 2e− ⇌ H2 + 2OH−) or bicarbonate (2HCO3− + 2e− ⇌ H2 + 2CO32−) in aqueous 0.5 M KHCO3, pH 8.3, electrolyte [66], where water reduction is kinetically more sluggish [71]. When protons are present, CO2 can be formed from bicarbonate in a non-faradaic reaction via HCO3− + H+ ⇌ CO2 + H2O. Protons are

• carbon fiber paper (FuelCell Store, AvCarb MGL190) was sonicated in 1.0 M aqueous sodium dodecyl sulfate solution (AG Scientific, ≥99%) and subsequently electrooxidized at +1.63 V vs Ag/AgCl for 20 min in aqueous 0.1 M KHCO3 solution (pH 8.3, Alfa Aesar, 99.7–100.5%). Laser-grafted gold nanoparticle

Graphene oxide–chloroquine conjugate induces DNA damage in A549 lung cancer cells through autophagy modulation

• Braham Dutt Arya,
• Sandeep Mittal,
• Prachi Joshi,
• Alok Kumar Pandey,
• Jaime E. Ramirez-Vick,
• Govind Gupta and
• Surinder P. Singh

Beilstein J. Nanotechnol. 2025, 16, 316–332, doi:10.3762/bjnano.16.24

• ice to allow gelation. Duplicate slides for each sample were prepared and were kept in freshly prepared and chilled lysis solution (146.1 g NaCl, 37.2 g EDTA, 1.2 g Tris, pH 10 with 1% Triton X 100 added just before use) at 4 °C overnight. Further, the slides were placed in a horizontal gel

• electrophoresis tank containing freshly prepared chilled electrophoresis solution (1 mM of EDTA, 300 mM of NaOH, pH > 13) for 20 min for DNA unwinding and subsequently subjected to electrophoresis with a 300 mA current, 0.7 V/cm at 4 °C under dimmed light for 30 min. After electrophoresis, the slides were treated

• with Tris buffer (0.4 M, pH 7.5) 3× at 5 min per cycle to neutralize excess alkaline solution, stained with 75 μL of ethidium bromide (20 µg/mL), and stored in a humidified slide box until scoring. The slides were scored using a fluorescent microscope (DMLB, Leica, Germany) coupled with a CCD camera

Enhancing mechanical properties of chitosan/PVA electrospun nanofibers: a comprehensive review

• Nur Areisman Mohd Salleh,
• Amalina Muhammad Afifi,
• Fathiah Mohamed Zuki and
• Hanna Sofia SalehHudin

Beilstein J. Nanotechnol. 2025, 16, 286–307, doi:10.3762/bjnano.16.22

• adsorbing heavy metals and radionuclides [16]. However, chitosan exhibits limited mechanical stability, is sensitive to pH variations, and tends to swell [17]. To improve the spinnability of chitosan during the electrospinning process, it is commonly blended with other polymers, such as PVA [18

Emerging strategies in the sustainable removal of antibiotics using semiconductor-based photocatalysts

• Yunus Ahmed,
• Keya Rani Dutta,
• Parul Akhtar,
• Md. Arif Hossen,
• Md. Jahangir Alam,
• Obaid A. Alharbi,
• Hamad AlMohamadi and
• Abdul Wahab Mohammad

Beilstein J. Nanotechnol. 2025, 16, 264–285, doi:10.3762/bjnano.16.21

• that of pure TiO2 and Fe2O3 under visible light illumination (500 W halogen lamp and wavelengths above 400 nm) [72]. At a dosage of 0.012 g/L of α-Fe2O3@TiO2 and pH 4.76, 98.8% of an initial CFX concentration of 20.5 mg/L was effectively removed after 103 min. The heterojunction formed between TiO2 and

• Fe2O3 promoted the electron–holes segregation rate and reduced the rate of recombination. A TiO2/GO/chitosan photocatalyst was synthesized by Erim et al. [73] for the degradation of CFX under UV-A irradiation. Under optimized conditions (catalyst dose of 0.327 g/L, CFX concentration of 20.29 mg/L, pH

• 4.1, and UV-A irradiation of 60 W), the TiO2/GO/chitosan photocatalyst exhibited a prominent degradation efficiency of 95.34%. They also reported in another article that the SWCNT/ZnO/Fe3O4 combination exhibited a CFX decomposition efficiency of 94.19% at pH 5.93, 22.76 ppm CFX, and 0.46 g/L

Radiosensitizing properties of dual-functionalized carbon nanostructures loaded with temozolomide

• Radmila Milenkovska,
• Nikola Geskovski,
• Dushko Shalabalija,
• Ljubica Mihailova,
• Petre Makreski,
• Dushko Lukarski,
• Igor Stojkovski,
• Maja Simonoska Crcarevska and
• Kristina Mladenovska

Beilstein J. Nanotechnol. 2025, 16, 229–251, doi:10.3762/bjnano.16.18

• -methyl-1-triazene-1-yl)imidazole-4-carboxamide) (MITC) is a first-line therapy for primary and recurrent GBM, especially O6-methylguanine-DNA methyltransferase (MGMT)-promotor-methylated tumors. MITC, acting via its metabolite methyl diazonium cation generated at physiological pH (>7), develops O6

• limited efficacy (due to the high level of DNA repair by MGMT and other mechanisms of resistance) [34]. In addition, the high hydrolytic instability of TMZ at pH ≥ 7 limits its efficacy, because the formed MTIC exhibits high systemic toxicity and cannot pass the BBTB and accumulate in the GBM, unlike TMZ

• . Therefore, it is of paramount importance to prolong the half-life of TMZ at physiological pH and to increase its accumulation in the tumor cells prior to degradation in the central circulation. Several strategies have been exploited to stabilize TMZ and overcome the disadvantages. Among them is the

Synthesis and the impact of hydroxyapatite nanoparticles on the viability and activity of rhizobacteria

• Bedah Rupaedah,
• Indrika Novella,
• Atiek Rostika Noviyanti,
• Diana Rakhmawaty Eddy,
• Anna Safarrida,
• Abdul Hapid,
• Zhafira Amila Haqqa,
• Suryana Suryana,
• Irwan Kurnia and
• Fathiyah Inayatirrahmi

Beilstein J. Nanotechnol. 2025, 16, 216–228, doi:10.3762/bjnano.16.17

• sustaining rhizobacterial viability with pH 8.95 and an electrical conductivity of 55.4 μS/cm. Rhizobacteria loaded onto the nHA carrier maintained comparable viability to those without carriers. The highest viability of the rhizobacterial strains Pd and Tb loaded onto the nHA carrier was observed on the

• the material, while the white areas represent the voids or pores within the material. For an overview of the characteristics of the nHA carrier, please refer to Table 1. The pH and EC values are important factors that influence the psychochemical properties of a material. Changes in pH and EC values

• can affect the stability of a substance, ion interactions, and molecular ionization in a solution. However, the effect of pH and EC values on the psychochemical properties highly depends on the material’s application [28][29]. Pd rhizobacterium typically thrives optimally at pH 7.5 and exhibits

Recent advances in photothermal nanomaterials for ophthalmic applications

• Jiayuan Zhuang,
• Linhui Jia,
• Chenghao Li,
• Rui Yang,
• Jiapeng Wang,
• Wen-an Wang,
• Heng Zhou and
• Xiangxia Luo

Beilstein J. Nanotechnol. 2025, 16, 195–215, doi:10.3762/bjnano.16.16

• rich functional groups and surface dangling bonds, enables the effective loading of drugs, targeting molecules, and antibodies [15]. When combined with thermal/pH-sensitive materials, shape memory materials, and hydrogels, they form an efficient platform for photothermal therapy [16]. The efficient

• sources, high adjustability, and ease of access, have paved the way for precise and controllable photothermal therapies. Notably, therapeutic platforms that integrate photothermal nanomaterials with drugs, antibodies, liposomes, hydrogels, heat/pH-sensitive materials, and shape memory materials have

Probing the potential of rare earth elements in the development of new anticancer drugs: single molecule studies

• Josiane A. D. Batista,
• Rayane M. de Oliveira,
• Carlos H. M. Lima,
• Milton L. Lana Júnior,
• Virgílio C. dos Anjos,
• Maria J. V. Bell and
• Márcio S. Rocha

Beilstein J. Nanotechnol. 2025, 16, 187–194, doi:10.3762/bjnano.16.15

• the stock solutions in a phosphate-buffered saline (PBS) buffer with [Na+] = 150 mM, pH 7.4. The samples used for OT assays consist of biotin-labeled λ DNA molecules (New England Biolabs N3011S) tethered by the ends between a streptavidin-coated coverslip and a streptavidin-coated polystyrene bead (3

• SM1711) in 10 mM Tris-HCl buffer with the addition of 10 mM of MgCl2 (pH 8.0), which is needed to reliably deposit the DNA molecules on mica substrates. PBS buffer cannot be used here since its high NaCl concentration disturbs the DNA adsorption on the substrates. The solution of DNA + ligand is first

Clays enhanced with niobium: potential in wastewater treatment and reuse as pigment with antibacterial activity

• Silvia Jaerger,
• Patricia Appelt,
• Mario Antônio Alves da Cunha,
• Fabián Ccahuana Ayma,
• Ricardo Schneider,
• Carla Bittencourt and
• Fauze Jacó Anaissi

Beilstein J. Nanotechnol. 2025, 16, 141–154, doi:10.3762/bjnano.16.13

• ) was used. A sodium hydroxide solution (NaOH, 1 mol·L−1) was dripped onto the clay powders until reaching a pH between 8 and 10. Subsequently, this suspension was blended with the transparent paint. Plaster molds were painted with both colorless and pigmented paint. After the paint dried, the color was

Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy

• Naths Grazia Sukubo,
• Paolo Bigini and
• Annalisa Morelli

Beilstein J. Nanotechnol. 2025, 16, 97–118, doi:10.3762/bjnano.16.10

• high buffering capacities in the acidic pH range of endosomes (pH 5–6). Lipid nanoparticles (LNPs), which include cationic and ionizable materials, exhibit such intracellularly triggered delivery mechanisms and are often used to carry nucleic acids into cells. In this case, the endosomal escape is

• polarization by targeting TERF2IP, activating STAT3, and inhibiting NF-κB [70][71]. Innovative delivery systems for miRNAs have further advanced their therapeutic application. Liu et al. developed a hybrid nanovector with dual redox/pH-responsive properties for targeted miRNA delivery in cancer therapy. This

• system, comprising galactose-functionalized polypeptides (GLC) coated with PEG-PLL copolymers (sPEG), was designed to release miR-155 specifically in the acidic tumor microenvironment. At neutral pH, the sPEG coating masked the cationic core, minimizing off-target effects, while at acidic pH, the coating

Characterization of ZnO nanoparticles synthesized using probiotic Lactiplantibacillus plantarum GP258

• Prashantkumar Siddappa Chakra,
• Aishwarya Banakar,
• Shriram Narayan Puranik,
• Vishwas Kaveeshwar,
• C. R. Ravikumar and
• Devaraja Gayathri

Beilstein J. Nanotechnol. 2025, 16, 78–89, doi:10.3762/bjnano.16.8

• according to [24] with slight modifications. The GP258 isolate was inoculated to MRS broth and incubated for 24 h at 37 °C. Further, the mixture was diluted fourfold using sterile distilled water and again incubated for 24 h. The culture broth was adjusted to pH 6 using 1 M NaOH, then to the culture broth

Instance maps as an organising concept for complex experimental workflows as demonstrated for (nano)material safety research

• Benjamin Punz,
• Maja Brajnik,
• Joh Dokler,
• Jaleesia D. Amos,
• Litty Johnson,
• Katie Reilly,
• Anastasios G. Papadiamantis,
• Amaia Green Etxabe,
• Lee Walker,
• Diego S. T. Martinez,
• Steffi Friedrichs,
• Klaus M. Weltring,
• Nazende Günday-Türeli,
• Claus Svendsen,
• Christine Ogilvie Hendren,
• Mark R. Wiesner,
• Martin Himly,
• Iseult Lynch and
• Thomas E. Exner

Beilstein J. Nanotechnol. 2025, 16, 57–77, doi:10.3762/bjnano.16.7

• nanomaterial properties, which can change as the surroundings change (such as zeta potential, which depends on the pH value and ionic strength of the surrounding medium [17]), and intrinsic nanomaterial properties, which are not affected by the surroundings (such as bandgap and structural arrangement) [18

• example are nodes relating to the components prior to their addition to the experiment, that is, information on the pristine nanomaterial, medium and soil, suppliers, batch numbers, CAS numbers, pH, and any other pre-processing steps before the addition into the experiment (mesocosm). For the first

• into raw and processed data, as well as the processes of their collection. The pink section nodes represent the raw data sets collected, such as the pH value of soil after the addition of the nanomaterial, organism biomass data, metal concentrations in organism tissues, and any processed data derived

Bioinspired nanofilament coatings for scale reduction on steel

• Siad Dahir Ali,
• Mette Heidemann Rasmussen,
• Jacopo Catalano,
• Christian Husum Frederiksen and
• Tobias Weidner

Beilstein J. Nanotechnol. 2025, 16, 25–34, doi:10.3762/bjnano.16.3

• . Synthetic seawater (pH 6), containing calcium carbonate, was pumped from one tank while soda ash (pH 11), containing sodium carbonate, was pumped from another tank. The solution had pH 9, leading to the formation of calcium carbonate. The flow rate was maintained at 0.88 L/min and the experiment was

A nanocarrier containing carboxylic and histamine groups with dual action: acetylcholine hydrolysis and antidote atropine delivery

• Elina E. Mansurova,
• Andrey A. Maslennikov,
• Anna P. Lyubina,
• Alexandra D. Voloshina,
• Irek R. Nizameev,
• Marsil K. Kadirov,
• Anzhela A. Mikhailova,
• Polina V. Mikshina,
• Albina Y. Ziganshina and
• Igor S. Antipin

Beilstein J. Nanotechnol. 2025, 16, 11–24, doi:10.3762/bjnano.16.2

• present in Figures S1 and S2 of Supporting Information File 1. The nanocarrier (p(Hist-CA)) was prepared, using the microemulsion technique [32][33], through the condensation of CA-RA and Hist-RA with phenylboronic acid (BA) in phosphate buffer (PB) at pH 8.5 [34][35]. CA-RA and Hist-RA are amphiphilic

• molecules. Within a microemulsion system, they self-assemble at the interface between water and oil. The hydrophilic groups face the aqueous phase, while the resorcinarene scaffold with tails on the lower rim points towards the dispersed (oil) phase. Under slightly basic conditions (pH 8.5), resorcinarenes

• react with BA to form boronate esters through cross-linking (Scheme 1). To synthesize p(Hist-CA), 4 mL of BA solution (1.25 mM) in PB, pH 8.5, and 7.3 μL of triolein (TO) were added to a mixture of Hist-RA (2 mM) and CA-RA (4.4 mM) in 1 mL of water. The mixture was vortexed for 1.5 min until an emulsion