Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer

• Filip Gorachinov,
• Fatima Mraiche,
• Diala Alhaj Moustafa,
• Ola Hishari,
• Yomna Ismail,
• Jensa Joseph,
• Maja Simonoska Crcarevska,
• Marija Glavas Dodov,
• Nikola Geskovski and
• Katerina Goracinova

Beilstein J. Nanotechnol. 2023, 14, 240–261, doi:10.3762/bjnano.14.23

• in mortality. Also, it is the second most frequently diagnosed cancer (11.4% of the total cases), surpassed only by female breast cancer (11.7%) [1][2][3]. According to the WHO International Agency for Research on Cancer in 2020 (GLOBOCAN database), around 1.8 million new lung mortalities were

Liquid phase exfoliation of talc: effect of the medium on flake size and shape

• Samuel M. Sousa,
• Helane L. O. Morais,
• Joyce C. C. Santos,
• Ana Paula M. Barboza,
• Bernardo R. A. Neves,
• Elisângela S. Pinto and
• Mariana C. Prado

Beilstein J. Nanotechnol. 2023, 14, 68–78, doi:10.3762/bjnano.14.8

• talc, when compared with the crystallographic database, and many are labeled. The insert shows the structure and chemical formula of talc [23]. Figure 1b shows the mineral that was milled to a fine powder. The powder was mixed with the exfoliation medium and subjected to mechanical energy provided by

Two-step single-reactor synthesis of oleic acid- or undecylenic acid-stabilized magnetic nanoparticles by thermal decomposition

• Mykhailo Nahorniak,
• Pamela Pasetto,
• Jean-Marc Greneche,
• Volodymyr Samaryk,
• Sandy Auguste,
• Anthony Rousseau,
• Nataliya Nosova and
• Serhii Varvarenko

Beilstein J. Nanotechnol. 2023, 14, 11–22, doi:10.3762/bjnano.14.2

• refinement. The collected XRD patterns were compared with the standard of maghemite and magnetite available in the International Centre for Diffraction Database (ICDD). Specific structural and magnetic properties of the synthesized NPM were studied using 57Fe Mössbauer spectroscopy at 77 K. The samples were

In search of cytotoxic selectivity on cancer cells with biogenically synthesized Ag/AgCl nanoparticles

• Mitzi J. Ramírez-Hernández,
• Mario Valera-Zaragoza,
• Omar Viñas-Bravo,
• Ariana A. Huerta-Heredia,
• Miguel A. Peña-Rico,
• Erick A. Juarez-Arellano,
• David Paniagua-Vega,
• Eduardo Ramírez-Vargas and
• Saúl Sánchez-Valdes

Beilstein J. Nanotechnol. 2022, 13, 1505–1519, doi:10.3762/bjnano.13.124

• letter number 56540 (Inorganic Crystal Structure Database, ICSD). This pattern corresponds to the crystallographic planes (111), (200), (220), (311), and (222) of the NaCl-type face-centered cubic crystal structure. According to the results, the pineapple peel extract (PPeel extract) is amorphous (i.e

Frequency-dependent nanomechanical profiling for medical diagnosis

• Santiago D. Solares and
• Alexander X. Cartagena-Rivera

Beilstein J. Nanotechnol. 2022, 13, 1483–1489, doi:10.3762/bjnano.13.122

• enable the generation of a database with rigorous nanomechanical measurements in a variety of healthy and diseased tissues, either classified by demographics and biometric factors, or according to disease progress for a specific patient. Figure 1 exemplifies an overall strategy for integrating AFM-based

• nanomechanical measurements into medical diagnosis, which includes specialized in vivo sensing, computer analysis (AFM force spectroscopy analysis), communication with the healthcare provider, and mining of the aggregate community database. Given the mechanical nature of AFM, the above strategy naturally fits

• evaluate when and where there is value added when introducing the desired method, and such evaluation should be based on quantifiable indicators. Fifth, if a clear benefit is identified, the team could proceed to a pilot evaluation stage at the clinical or hospital level, where a database of patient

Structural studies and selected physical investigations of LiCoO₂ obtained by combustion synthesis

• Monika Michalska,
• Paweł Ławniczak,
• Tomasz Strachowski,
• Adam Ostrowski and
• Waldemar Bednarski

Beilstein J. Nanotechnol. 2022, 13, 1473–1482, doi:10.3762/bjnano.13.121

• values (a0 = 2.81498 Å, c0 = 14.0493 Å, V0 = 96.41 Å3) of the ICDD PDF card. All the lattice constants are similar to “ideal” patterns (in the PDF4+2021 ICDD database, the lattice constants for a fixed stoichiometric dispersion pattern are a = 2.792–2.856 Å, c = 14.033–14.289 Å) and are within the range

Rapid and sensitive detection of box turtles using an electrochemical DNA biosensor based on a gold/graphene nanocomposite

• Abu Hashem,
• M. A. Motalib Hossain,
• Ab Rahman Marlinda,
• Mohammad Al Mamun,
• Khanom Simarani and
• Mohd Rafie Johan

Beilstein J. Nanotechnol. 2022, 13, 1458–1472, doi:10.3762/bjnano.13.120

• NCBI database (https://www.ncbi.nlm.nih.gov/) and aligned using the MEGA5.2 [73] sequence alignment software followed by ClustalW [74] to find intraspecies conserved and interspecies hypervariable regions. The specific DNA sequence of BT was selected as a probe by comparing the BT cytb gene sequence

• sequences in the online database. The designed probe was modified with a thiol modifier to facilitate covalent attachment with AuNPs on the modified electrode surface, and a six-carbon spacer arm was added to facilitate extrusion from the electrode surface. The designed DNA sequences were synthesised from

Straight roads into nowhere – obvious and not-so-obvious biological models for ferrophobic surfaces

• Wilfried Konrad,
• Christoph Neinhuis and
• Anita Roth-Nebelsick

Beilstein J. Nanotechnol. 2022, 13, 1345–1360, doi:10.3762/bjnano.13.111

• -down strategy. They were included into various information resources on functional biological models, such as the popular and widely used “Ask nature” database (Biomimicry Institute, 2020. AskNature – Innovation Inspired by Nature. https://asknature.org/, [6]). In other words, once their functional

Design and selection of peptides to block the SARS-CoV-2 receptor binding domain by molecular docking

• Kendra Ramirez-Acosta,
• Ivan A. Rosales-Fuerte,
• J. Eduardo Perez-Sanchez,
• Alfredo Nuñez-Rivera,
• Josue Juarez and
• Ruben D. Cadena-Nava

Beilstein J. Nanotechnol. 2022, 13, 699–711, doi:10.3762/bjnano.13.62

• peptides to neutralize the infective mechanism of SARS-CoV-2 through the RBD is an interesting strategy. The binding ability of 104 peptides (University of Nebraska Medical Center’s Antimicrobial Peptide Database) to the RBD was assessed using molecular docking. Based on the molecular docking results

• was used to perform molecular docking of 104 biological peptides, selected from the University of Nebraska Medical Center’s Antimicrobial Peptide Database (APD) [22][23][24], and theoretical peptides with the region of the SARS-CoV-2 RBD that binds to the cellular receptor ACE2 (called the RBD active

• Database [22][23][24]. The peptides were selected based on their previously reported antiviral activity in order to perform a massive docking experiment. PDB files were gathered for those peptides that possess a reported three-dimensional structure and a 3D structure was predicted through I-TASSER’s and

Interfacial nanoarchitectonics for ZIF-8 membranes with enhanced gas separation

• Season S. Chen,
• Zhen-Jie Yang,
• Chia-Hao Chang,
• Hoong-Uei Koh,
• Sameerah I. Al-Saeedi,
• Kuo-Lun Tung and
• Kevin C.-W. Wu

Beilstein J. Nanotechnol. 2022, 13, 313–324, doi:10.3762/bjnano.13.26

• synthesis method. Figure 1a shows that the XRD patterns of the as-synthesized free-standing ZIF-8 thin film was identical to that of a ZIF-8 crystal simulated with data from Crystallography Open Database (Mercury, version 3.6), indicating the success of the synthesis of ZIF-8 crystals by interfacial

Chemical vapor deposition of germanium-rich CrGe_x nanowires

• Vladislav Dřínek,
• Stanislav Tiagulskyi,
• Roman Yatskiv,
• Jan Grym,
• Radek Fajgar,
• Věra Jandová,
• Martin Koštejn and
• Jaroslav Kupčík

Beilstein J. Nanotechnol. 2021, 12, 1365–1371, doi:10.3762/bjnano.12.100

• with the database PDF (00-004-0545) for cubic germanium (d111 = 0.3266 nm). The atomic elemental ratio [Cr]/[Ge] in the coating was in the range of 1:(6–7) (Supporting Information File 1, Figure S8). XP spectra showed the presence of Ge, Cr, and O. In order to reduce surface contamination and oxidized

Biocompatibility and cytotoxicity in vitro of surface-functionalized drug-loaded spinel ferrite nanoparticles

• Sadaf Mushtaq,
• Khuram Shahzad,
• Tariq Saeed,
• Anwar Ul-Hamid,
• Bilal Haider Abbasi,
• Nafees Ahmad,
• Waqas Khalid,
• Muhammad Atif,
• Zulqurnain Ali and
• Rashda Abbasi

Beilstein J. Nanotechnol. 2021, 12, 1339–1364, doi:10.3762/bjnano.12.99

• of 0.47, 0.25, 0.24, and 0.20 nm for FeO, CFO, NFO and ZFO, respectively, corresponding to (111), (311), (311), and (400), respectively. These planes are well-matched with the interplanar distance of the diffraction pattern standards obtained from their standard JCPDS database. Weight and atomic % of

Identifying diverse metal oxide nanomaterials with lethal effects on embryonic zebrafish using machine learning

• Richard Liam Marchese Robinson,
• Haralambos Sarimveis,
• Philip Doganis,
• Xiaodong Jia,
• Marianna Kotzabasaki,
• Christiana Gousiadou,
• Stacey Lynn Harper and
• Terry Wilkins

Beilstein J. Nanotechnol. 2021, 12, 1297–1325, doi:10.3762/bjnano.12.97

• […] with the convenience of cell culture” [25] and that “zebrafish exhibit remarkable similarity to other high-order vertebrates including humans” [23]. Hence, the Nanomaterial Biological Interactions (NBI) Knowledgebase [26], a publicly available database of ENM embryonic zebrafish test results for

• various lethal and sub-lethal biological endpoints, determined at a range of test concentrations, is a valuable resource for developing human safety relevant nano-QSAR models. Importantly, all biological data from this database were obtained in the same laboratory (Harper Laboratory, Oregon State

pH-driven enhancement of anti-tubercular drug loading on iron oxide nanoparticles for drug delivery in macrophages

• Karishma Berta Cotta,
• Sarika Mehra and
• Rajdip Bandyopadhyaya

Beilstein J. Nanotechnol. 2021, 12, 1127–1139, doi:10.3762/bjnano.12.84

• distribution of these particles was also high, i.e., FWHM of 670.94 nm, resulting from the variation in particle aggregate sizes. The XRD pattern obtained for the synthesized particles were in accordance with the pattern observed in the XRD database for iron oxide (COD: 9013529) [32] (Figure 2c). The zeta

Fate and transformation of silver nanoparticles in different biological conditions

• Barbara Pem,
• Marija Ćurlin,
• Darija Domazet Jurašin,
• Valerije Vrček,
• Rinea Barbir,
• Vedran Micek,
• Raluca M. Fratila,
• Jesus M. de la Fuente and
• Ivana Vinković Vrček

Beilstein J. Nanotechnol. 2021, 12, 665–679, doi:10.3762/bjnano.12.53

• ) were dispersed in ultrapure water (UPW) and examined by TEM to confirm their original morphology. These coating agents were selected according to their relevance in biomedicine, as they are the most frequently used stabilization agents for AgNPs according to the Web of Science database [41]. Moreover

• three. The proton at position six overlapped with the solvent signal and thus is not shown. The peaks were assigned according to AIST Spectral Database for Organic Compounds [55]. Then, a 5 mM solution of AgNO3 was added and the mixture was left to react for 2 h. During that time, the solution became

A review of defect engineering, ion implantation, and nanofabrication using the helium ion microscope

• Frances I. Allen

Beilstein J. Nanotechnol. 2021, 12, 633–664, doi:10.3762/bjnano.12.52

A review on the biological effects of nanomaterials on silkworm (Bombyx mori)

• Sandra Senyo Fometu,
• Guohua Wu,
• Lin Ma and
• Joan Shine Davids

Beilstein J. Nanotechnol. 2021, 12, 190–202, doi:10.3762/bjnano.12.15

• studying cellular toxicity, response to new drugs [78] and environmental pollution. Silkworm (Bombyx mori) is an invertebrate insect widely used as a model organism in life sciences [79] since it has diverse mutant strains, a complete genome sequenced, and a protein database available [80][81]. There are

Oxidation of Au/Ag films by oxygen plasma: phase separation and generation of nanoporosity

• Abdel-Aziz El Mel,
• Said A. Mansour,
• Mujaheed Pasha,
• Atef Zekri,
• Janarthanan Ponraj,
• Akshath Shetty and
• Yousef Haik

Beilstein J. Nanotechnol. 2020, 11, 1608–1614, doi:10.3762/bjnano.11.143

• microspheres were hollow or not. Scale bar: 1 µm. XRD patterns recorded on Au/Ag samples exposed to oxygen plasma for different durations. The powder diagrams represented by the columns were plotted using the following database files: Au/Ag JCDPS 01-071-9134; AgO cubic phase JCDPS 01-076-1489; AgO silver(I,III

Cu₂O nanoparticles for the degradation of methyl parathion

• Juan Rizo,
• David Díaz,
• Benito Reyes-Trejo and
• M. Josefina Arellano-Jiménez

Beilstein J. Nanotechnol. 2020, 11, 1546–1555, doi:10.3762/bjnano.11.137

• mm, a step width of 0.01407°, and 0.5 s time per step were used. Qualitative analysis was performed with the DiffracPlus Eva software package (Bruker AXS, Germany) using the PDF-2 database. High-resolution transmission electron microscopy (HRTEM) images were obtained in a JEOL 2010F microscope

Magnetic-field-assisted synthesis of anisotropic iron oxide particles: Effect of pH

• Andrey V. Shibaev,
• Petr V. Shvets,
• Darya E. Kessel,
• Roman A. Kamyshinsky,
• Anton S. Orekhov,
• Sergey S. Abramchuk,
• Alexei R. Khokhlov and
• Olga E. Philippova

Beilstein J. Nanotechnol. 2020, 11, 1230–1241, doi:10.3762/bjnano.11.107

• diffractogramms represent the diffraction pattern of the reference sample (commercial Fe3O4). Attribution of the diffraction rings for the reference sample was obtained from the International Centre for Diffraction Data (ICDD) database. 1D electron diffraction patterns obtained by the radial averaging of 2D

Applications of superparamagnetic iron oxide nanoparticles in drug and therapeutic delivery, and biotechnological advancements

• Maria Suciu,
• Corina M. Ionescu,
• Alexandra Ciorita,
• Septimiu C. Tripon,
• Dragos Nica,
• Hani Al-Salami and
• Lucian Barbu-Tudoran

Beilstein J. Nanotechnol. 2020, 11, 1092–1109, doi:10.3762/bjnano.11.94

• 2015 and January 2020. The graphics of publication counts per year were obtained using the values obtained from Web of Science Core Collection database and Medline (PubMed) trend website [22][23], using the following keywords: "superparamagnetic iron oxide", "SPION", "iron oxide medical" for the period

Nickel nanoparticles supported on a covalent triazine framework as electrocatalyst for oxygen evolution reaction and oxygen reduction reactions

• Secil Öztürk,
• Yu-Xuan Xiao,
• Dennis Dietrich,
• Beatriz Giesen,
• Juri Barthel,
• Jie Ying,
• Xiao-Yu Yang and
• Christoph Janiak

Beilstein J. Nanotechnol. 2020, 11, 770–781, doi:10.3762/bjnano.11.62

• crystallographic open database (CrOD) files. TEM images of Ni/CTF-1-600-22 showing (a) Ni nanoparticles supported on CTF, (b,c) the aggregation of the primary Ni nanoparticles and (d) the lattice planes of the Ni nanoparticles. SEM images and EDX elemental mappings of Ni for (a) Ni/CTF-1-400-20, (b) Ni/CTF1-400-35

Stochastic excitation for high-resolution atomic force acoustic microscopy imaging: a system theory approach

• Edgar Cruz Valeriano,
• José Juan Gervacio Arciniega,
• Christian Iván Enriquez Flores,
• Susana Meraz Dávila,
• Joel Moreno Palmerin,
• Martín Adelaido Hernández Landaverde,
• Yuri Lizbeth Chipatecua Godoy,
• Aime Margarita Gutiérrez Peralta,
• Rafael Ramírez Bon and
• José Martín Yañez Limón

Beilstein J. Nanotechnol. 2020, 11, 703–716, doi:10.3762/bjnano.11.58

• cantilever using white-noise as an excitation signal and the FFT algorithm. These resonance frequencies were fitted according to a database, which was computed using the free cantilever model described in Equation 21 and the particle swarm optimization algorithm [33][34][35][36], in order to obtain the

• geometrical parameters for the experimental cantilever. The database describes each cantilever according to length L, width a, thickness b, inertia moment I = ab3/12, linear mass m = ρA, where A is the cross-sectional area of the cantilever and ρ = 2330 kg/m3 [37] is the density of the cantilever. The

• database has 10000 cantilevers where L ∈ [440,500] µm, a ∈ [40,50] µm, b ∈ [1,3] µm. The optimization criteria are where erms is the root mean square error, fn is the n-th measured free resonance frequency, and is the n-th theoretical free resonance frequency. For this work, using this optimization

Identification of physicochemical properties that modulate nanoparticle aggregation in blood

• Ludovica Soddu,
• Duong N. Trinh,
• Eimear Dunne,
• Dermot Kenny,
• Giorgia Bernardini,
• Ida Kokalari,
• Arianna Marucco,
• Marco P. Monopoli and
• Ivana Fenoglio

Beilstein J. Nanotechnol. 2020, 11, 550–567, doi:10.3762/bjnano.11.44

• were sequentially isolated and fragmented by higher-energy C-trap dissociation. MS raw files were processed with MaxQuant software (version 1.6.2). The peak lists were searched against the human FASTA database. The search included the modifications of cysteine carbamidomethylation, methionine oxidation

• and protein N-terminal acetylation. A maximum of two missed trypsin cleavages were allowed in the database search. The false discovery rate for both peptides and proteins was set at 1%. After that, the ProteinGroup file from Maxquant was processed, filtered and analysed with Perseus software to

Correction: Photocatalytic antibacterial performance of TiO₂ and Ag-doped TiO₂ against S. aureus. P. aeruginosa and E. coli

• Kiran Gupta,
• R. P. Singh,
• Ashutosh Pandey and
• Anjana Pandey

Beilstein J. Nanotechnol. 2020, 11, 547–549, doi:10.3762/bjnano.11.43

• the measured XRD pattern to powder diffraction patterns in the International Centre for Diffraction Data (ICDD) database. The characteristic peaks of the TiO2 nanoparticle sample indicate an anatase phase (2θ = 24.8°, 44.5°, compared with JCPDS file no. 00-021-1272) with some indication of a rutile