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Search for "dissolution" in Full Text gives 274 result(s) in Beilstein Journal of Nanotechnology. Showing first 200.

Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study

  • Nittiya Suwannasom,
  • Netsai Sriaksorn,
  • Chutamas Thepmalee,
  • Krissana Khoothiam,
  • Ausanai Prapan,
  • Hans Bäumler and
  • Chonthida Thephinlap

Beilstein J. Nanotechnol. 2023, 14, 1127–1140, doi:10.3762/bjnano.14.93

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  • poorly water-soluble CUR. An effective submicron particle fabrication technique, namely co-precipitation–cross-linking–dissolution (CCD), has been established to produce biopolymer particles [24][25][26]. In this method, biopolymer particles are produced via co-precipitation, by simply mixing MnCl2 and
  • -HSA-MPs and HSA was cross-linked. After dissolution of the MnCO3 template with EDTA, a colloidal particle suspension of CUR-HSA-MPs was obtained. Comparison of the different CUR samples demonstrated that the color of CUR in DMSO is light brown, indicating dissolved CUR; CUR in water is bright yellow
  • albumin proteins [30]. CUR showed strong binding affinity towards HSA, likely at the tryptophan residue, which is present in the hydrophobic cavities of HSA [23][31]. The final CUR-HSA-MPs are obtained after dissolution of the MnCO3 template with EDTA. Characterization of CUR-HSA-MPs Dynamic light
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Published 21 Nov 2023

Recognition mechanisms of hemoglobin particles by monocytes – CD163 may just be one

  • Jonathan-Gabriel Nimz,
  • Pichayut Rerkshanandana,
  • Chiraphat Kloypan,
  • Ulrich Kalus,
  • Saranya Chaiwaree,
  • Axel Pruß,
  • Radostina Georgieva,
  • Yu Xiong and
  • Hans Bäumler

Beilstein J. Nanotechnol. 2023, 14, 1028–1040, doi:10.3762/bjnano.14.85

Graphical Abstract
  • coprecipitation–crosslinking–dissolution (CCD) are promising as HBOCs. CCD provides particles that are malleable and show a consistent morphology and narrow size distribution, as well as a negative zeta potential [19][31][32][33]. It could be shown that neither NO scavenging nor vasoconstriction can be detected
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Published 19 Oct 2023

N-Heterocyclic carbene-based gold etchants

  • Robert B. Chevalier,
  • Justin Pantano,
  • Matthew K. Kiesewetter and
  • Jason R. Dwyer

Beilstein J. Nanotechnol. 2023, 14, 865–871, doi:10.3762/bjnano.14.71

Graphical Abstract
  • dissolution of gold. We present scanning electron micrographs and elemental imaging analyses by energy dispersive X-ray spectroscopy to examine the effect of solutions of each species on the gold film. This work highlights the risk of unwanted etching during some routes to NHC-based surface functionalization
  • solubility) of 2 and 3 must also be considered as a contributing factor. Similarly, Figure S4 (Supporting Information File 1) shows no apparent gold film loss in a solution of triethylamine and potassium iodide in acetone (chosen instead of THF or DCM to allow for dissolution of KI) tested as a control for
  • the present work we show that one must carefully consider the particular NHC-related species, the solvent, the exposure time, and the concentration in order to avoid deleterious effects such as dissolution of the gold film or nanoparticle substrate. At the same time, we introduce a molecular etchant
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Published 21 Aug 2023

Nanostructured lipid carriers containing benznidazole: physicochemical, biopharmaceutical and cellular in vitro studies

  • Giuliana Muraca,
  • María Esperanza Ruiz,
  • Rocío C. Gambaro,
  • Sebastián Scioli-Montoto,
  • María Laura Sbaraglini,
  • Gisel Padula,
  • José Sebastián Cisneros,
  • Cecilia Yamil Chain,
  • Vera A. Álvarez,
  • Cristián Huck-Iriart,
  • Guillermo R. Castro,
  • María Belén Piñero,
  • Matias Ildebrando Marchetto,
  • Catalina Alba Soto,
  • Germán A. Islan and
  • Alan Talevi

Beilstein J. Nanotechnol. 2023, 14, 804–818, doi:10.3762/bjnano.14.66

Graphical Abstract
  • BNZ within NLC because of its small quantity or to dissolution inside the NLC. The long period Bragg diffraction peaks for Myristyl myristate could be observed in SAXS patterns at the q range between 0.15 and 0.2 Å−1 (Figure 6). Bare myristyl myristate confirmed the presence of a β’ polymorph with
  • at 324 nm. The volume of injection was 20 μL. In vitro benznidazole release assay The release of BNZ from the nanoparticles was performed in a rotating paddle apparatus (Vision Classic 6, Hanson Research, Chatsworth, CA, USA) at 75 rpm using 500 mL of KH2PO4 buffer (pH 6.8) as the dissolution medium
  • . The bath temperature was set at 37.0 ± 0.5 °C. A volume of 5 mL of each formulation was placed in a pre-hydrated dialysis membrane (MWCO 10 kDa) and submerged into the dissolution vessels. A solution of free BNZ at the same concentration was used as control. At 0, 5, 10, 15, and 30 min, and at 1, 2, 3
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Published 28 Jul 2023

Carboxylic acids and light interact to affect nanoceria stability and dissolution in acidic aqueous environments

  • Matthew L. Hancock,
  • Eric A. Grulke and
  • Robert A. Yokel

Beilstein J. Nanotechnol. 2023, 14, 762–780, doi:10.3762/bjnano.14.63

Graphical Abstract
  • of nanoceria (i.e., cerium oxide in the form of nanoparticles) can store or release oxygen, cycling between Ce3+ and Ce4+; therefore, they can cause or relieve oxidative stress within living systems. Nanoceria dissolution occurs in acidic environments. Nanoceria stabilization is a known problem even
  • dissolution and stabilization have been previously studied in vitro using acidic aqueous environments. Nanoceria agglomerated in the presence of some carboxylic acids over 30 weeks, and degraded in others, at pH 4.5 (i.e., the pH value in phagolysosomes). Plants release carboxylic acids, and cerium
  • did not occur in the dark in the presence of most carboxylic acids. Light initiates free radicals generated by ceria nanoparticles. Nanoceria completely dissolved in the presence of citric, malic, and isocitric acid when exposed to light, attributed to nanoceria dissolution, release of Ce3+ ions, and
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Published 27 Jun 2023

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

  • Akeem Adeyemi Oladipo,
  • Saba Derakhshan Oskouei and
  • Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

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Published 01 Jun 2023

Evaluation of electrosynthesized reduced graphene oxide–Ni/Fe/Co-based (oxy)hydroxide catalysts towards the oxygen evolution reaction

  • Karolina Cysewska,
  • Marcin Łapiński,
  • Marcin Zając,
  • Jakub Karczewski,
  • Piotr Jasiński and
  • Sebastian Molin

Beilstein J. Nanotechnol. 2023, 14, 420–433, doi:10.3762/bjnano.14.34

Graphical Abstract
  • friendly nature [11]. Even though transition-metal-based catalysts still suffer from low surface areas [12], dissolution and aggregation of metallic phase and metal oxides during the active OER process occurs [13]. Hence, Ni-, Fe- and/or Co-based catalysts have been synthesized as hybrid catalysts with
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Published 29 Mar 2023

Quercetin- and caffeic acid-functionalized chitosan-capped colloidal silver nanoparticles: one-pot synthesis, characterization, and anticancer and antibacterial activities

  • Akif Hakan Kurt,
  • Elif Berna Olutas,
  • Fatma Avcioglu,
  • Hamza Karakuş,
  • Mehmet Ali Sungur,
  • Cansu Kara Oztabag and
  • Muhammet Yıldırım

Beilstein J. Nanotechnol. 2023, 14, 362–376, doi:10.3762/bjnano.14.31

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  • biggest problems in the development of new drugs [3]. One of the approaches to overcome these problems is nanoparticle carriers. These carriers are advantageous because their high surface area and good adhesion to biological surfaces increase solubility and dissolution rate [4]. The Gram-positive
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Published 20 Mar 2023

Polymer nanoparticles from low-energy nanoemulsions for biomedical applications

  • Santiago Grijalvo and
  • Carlos Rodriguez-Abreu

Beilstein J. Nanotechnol. 2023, 14, 339–350, doi:10.3762/bjnano.14.29

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  • nanomedicine has yielded several relevant advancements since its beginnings in the early 2000s. The dissolution kinetics of poorly soluble drugs have been improved by the production of drug nanocrystals, enabling continuous drug release. Lipid molecular structures have been manipulated at the nanoscale to
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Published 13 Mar 2023

Cyclodextrins as eminent constituents in nanoarchitectonics for drug delivery systems

  • Makoto Komiyama

Beilstein J. Nanotechnol. 2023, 14, 218–232, doi:10.3762/bjnano.14.21

Graphical Abstract
  • enhances the hydrophobic interactions of the poly(N-isopropylacrylamide) segments, stabilizing the hydrogel. The anticancer drug DOX encapsulated in the hydrophobic core is slowly released through the dissolution of the hydrogel to micelles. By modifying β-CyD with both N-acetyl-ʟ-cysteine and arginine
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Published 09 Feb 2023

Antimicrobial and mechanical properties of functionalized textile by nanoarchitectured photoinduced Ag@polymer coating

  • Jessica Plé,
  • Marine Dabert,
  • Helene Lecoq,
  • Sophie Hellé,
  • Lydie Ploux and
  • Lavinia Balan

Beilstein J. Nanotechnol. 2023, 14, 95–109, doi:10.3762/bjnano.14.11

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  • (PEG600DA) and pentaerythritol triacrylate monomer (PETIA) used as comonomer (PEG600DA/PETIA with a 1:1 weight ratio) were mixed under magnetic stirring with diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide (0.5 wt %) and the metal precursor AgNO3 (3 wt % and 5 wt %) for 1 h. After complete dissolution, this
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Published 12 Jan 2023

Solvent-induced assembly of mono- and divalent silica nanoparticles

  • Bin Liu,
  • Etienne Duguet and
  • Serge Ravaine

Beilstein J. Nanotechnol. 2023, 14, 52–60, doi:10.3762/bjnano.14.6

Graphical Abstract
  • , 9, and 14 iterative silica growth steps, with measured diameter of the silica cap of 130, 165, 195, 250, and 315 nm, respectively. The selective dissolution of the physically entangled PS chains by three centrifugation/redispersion cycles in 20 mL of THF was thus performed to get the 1-PSN with
  • next generation. The final diameter of the silica core of the bipods was 190 nm. Dissolution of the PS nodules For dissolving the PS nodules of the monopods and bipods, three centrifugation/redispersion cycles in 20 mL of THF (12,000g; 10 min) were performed. The concentration of 1-PSN and 2-PSN
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Published 06 Jan 2023

Induced electric conductivity in organic polymers

  • Konstantin Y. Arutyunov,
  • Anatoli S. Gurski,
  • Vladimir V. Artemov,
  • Alexander L. Vasiliev,
  • Azat R. Yusupov,
  • Danfis D. Karamov and
  • Alexei N. Lachinov

Beilstein J. Nanotechnol. 2022, 13, 1551–1557, doi:10.3762/bjnano.13.128

Graphical Abstract
  • amount of solvent until complete dissolution, then the solvent was added in the required amount, and the solution was kept for another day in the dark. For fabrication of films of various thicknesses, solutions of polymers in cyclohexanone with concentrations of 0.1–15 wt % were used. The polymer
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Published 19 Dec 2022

Hydroxyapatite–bioglass nanocomposites: Structural, mechanical, and biological aspects

  • Olga Shikimaka,
  • Mihaela Bivol,
  • Bogdan A. Sava,
  • Marius Dumitru,
  • Christu Tardei,
  • Beatrice G. Sbarcea,
  • Daria Grabco,
  • Constantin Pyrtsac,
  • Daria Topal,
  • Andrian Prisacaru,
  • Vitalie Cobzac and
  • Viorel Nacu

Beilstein J. Nanotechnol. 2022, 13, 1490–1504, doi:10.3762/bjnano.13.123

Graphical Abstract
  • , which exhibits a strong correlation with porosity, as well as on the mineralization capability and cell viability due to the different dissolution rate. Keywords: bioactivity; hardness; microstructure; nanocomposites; porosity; Introduction Within the last decades increasing emphasis is placed on the
  • bioactivity of the glass, which has a higher dissolution rate and promotes the formation of a carbonated hydroxyapatite (CHA) layer on its surface, which is responsible for implant–bone bonding [6]. The composition of the most famous bioglass, 45S5 Bioglass [7], includes the principal elements of the bone, Ca
  • , therefore, higher dissolution rate. HAP-based composites with a denser structure need a longer period of immersion in SBF for solubilization and the beginning of the mineralization process. And indeed, after 5 days of soaking, a well-pronounced precipitate was observed on HAP-based composites, too (Figure
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Published 12 Dec 2022

Structural studies and selected physical investigations of LiCoO2 obtained by combustion synthesis

  • Monika Michalska,
  • Paweł Ławniczak,
  • Tomasz Strachowski,
  • Adam Ostrowski and
  • Waldemar Bednarski

Beilstein J. Nanotechnol. 2022, 13, 1473–1482, doi:10.3762/bjnano.13.121

Graphical Abstract
  • by the phase transition from a hexagonal structure to a monoclinic structure, which occurs during cathode charging at a potential of approximately 4.2 V [5][6][7][8][9]. A decrease in capacity (approx. 50%) is observed during the cycling charging–discharging processes, caused by the dissolution of
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Published 07 Dec 2022

Facile preparation of Au- and BODIPY-grafted lipid nanoparticles for synergized photothermal therapy

  • Yuran Wang,
  • Xudong Li,
  • Haijun Chen and
  • Yu Gao

Beilstein J. Nanotechnol. 2022, 13, 1432–1444, doi:10.3762/bjnano.13.118

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  • –visible (UV–vis) absorption spectra were measured with an UV–vis spectrometer (Q-5000, Quawell, America). The amounts of BDP in AB-LNPs were analyzed using UV–vis spectroscopy after the dissolution of AB-LNPs in DMSO by measuring the absorbance at a wavelength of 600 nm. The loading efficiency (LE, %) was
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Published 02 Dec 2022

Orally administered docetaxel-loaded chitosan-decorated cationic PLGA nanoparticles for intestinal tumors: formulation, comprehensive in vitro characterization, and release kinetics

  • Sedat Ünal,
  • Osman Doğan and
  • Yeşim Aktaş

Beilstein J. Nanotechnol. 2022, 13, 1393–1407, doi:10.3762/bjnano.13.115

Graphical Abstract
  • release profile is that CS on the NP surface absorbed the DCX molecules. The first interaction between the formulations and the low pH medium caused a release of DCX molecules attached to the CS surface of the NPs. Another reason why CS-coated PLGA NPs exhibited fast dissolution in acidic medium might be
  • models although both formulations have similar dissolution profiles. The main difference between the two formulations is the CS coating. The release profiles were different at the beginning, and a faster release was observed from CS-coated nanoparticles. However, in the following process, the film layer
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Published 23 Nov 2022

Microneedle-based ocular drug delivery systems – recent advances and challenges

  • Piotr Gadziński,
  • Anna Froelich,
  • Monika Wojtyłko,
  • Antoni Białek,
  • Julia Krysztofiak and
  • Tomasz Osmałek

Beilstein J. Nanotechnol. 2022, 13, 1167–1184, doi:10.3762/bjnano.13.98

Graphical Abstract
  • advantage of soluble inserts is that they do not have to be removed from the eye. The rate of drug release is influenced by dissolution or erosion of the polymer matrix. Ophthalmic therapeutic systems belong to the group of non-biodegradable inserts from which the drug substance is released by diffusion at
  • intended to deliver active ingredients that are sensitive to heat, as these systems can be prepared from water-based polymer solutions at room temperature. The polymer dissolves in the tissue after the administration and the incorporated drug is released in this way. The dissolution time required to
  • dissolution, approximately 30 s, in which the active substance was completely released, followed by a rapid onset of action. At the same time, it was emphasized that the manufacturing process did not reduce the antifungal activity of the drug [176]. Shi et al. proposed PLA/HA MNs for the ocular delivery of
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Published 24 Oct 2022

Temperature and chemical effects on the interfacial energy between a Ga–In–Sn eutectic liquid alloy and nanoscopic asperities

  • Yujin Han,
  • Pierre-Marie Thebault,
  • Corentin Audes,
  • Xuelin Wang,
  • Haiwoong Park,
  • Jian-Zhong Jiang and
  • Arnaud Caron

Beilstein J. Nanotechnol. 2022, 13, 817–827, doi:10.3762/bjnano.13.72

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  • Au. For this reason, we assume that a small amount of gold dissolved in the metallic melt investigated here. However, the dissolution of Au should be small since it is thermally activated. In the current study, we could not observe any degradation of the Au tip nor measure traces of Au in liquid Ga
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Published 23 Aug 2022

Antibacterial activity of a berberine nanoformulation

  • Hue Thi Nguyen,
  • Tuyet Nhung Pham,
  • Anh-Tuan Le,
  • Nguyen Thanh Thuy,
  • Tran Quang Huy and
  • Thuy Thi Thu Nguyen

Beilstein J. Nanotechnol. 2022, 13, 641–652, doi:10.3762/bjnano.13.56

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  • nanoparticles produced by EPN and ASP techniques have notably increased solubility and dissolution rate due to their semicrystalline form. The small size of the nanoparticles can be obtained by adjusting the drug concentration, flow rate, stirring rate, and antisolvent volume in EPN and ASP methods [28]. Many
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Published 11 Jul 2022

Ciprofloxacin-loaded dissolving polymeric microneedles as a potential therapeutic for the treatment of S. aureus skin infections

  • Sharif Abdelghany,
  • Walhan Alshaer,
  • Yazan Al Thaher,
  • Maram Al Fawares,
  • Amal G. Al-Bakri,
  • Saja Zuriekat and
  • Randa SH. Mansour

Beilstein J. Nanotechnol. 2022, 13, 517–527, doi:10.3762/bjnano.13.43

Graphical Abstract
  • model. This was evidenced by a zone of inhibition of 29 mm for the microneedle formulation of ciprofloxacin (CIP_MN1) compared to 2 mm for the free gel of ciprofloxacin. Furthermore, the CIP_MN1 showed complete dissolution in human skin after 60 min from application. Finally, the skin deposition of
  • . aureus skin infections was investigated. Recent studies showed that dissolving polymeric microneedles are a promising approach in topical and transdermal drug delivery because of the rapid dissolution and/or degradation of the polymer, which, in turn, releases the incorporated drug [18]. These dissolving
  • human skin. Also, the dissolution of these microneedles in excised human skin and the concentration of ciprofloxacin in each layer of the excised human skin was studied. We designed an in vitro model of skin infection to compare the microneedles with free gel and, consequently, the antimicrobial
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Published 15 Jun 2022

A non-enzymatic electrochemical hydrogen peroxide sensor based on copper oxide nanostructures

  • Irena Mihailova,
  • Vjaceslavs Gerbreders,
  • Marina Krasovska,
  • Eriks Sledevskis,
  • Valdis Mizers,
  • Andrejs Bulanovs and
  • Andrejs Ogurcovs

Beilstein J. Nanotechnol. 2022, 13, 424–436, doi:10.3762/bjnano.13.35

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  • explains why it is impossible to obtain the developed nanostructured CuO surface at room temperature. However, after increasing the concentration of NaOH to 10–15 M, the dissolution–secondary precipitation mechanism takes effect: Cu(OH)2 reacts with OH− ions to form the complex ion [Cu(OH)4]2− (Equation 2
  • short time. The particles begin to agglomerate in order to minimize the total surface energy, forming spherical seeds, which, according to the mechanism of dissolution–secondary precipitation [78][80], overgrow with CuO petals, thereby forming 3D structures in solution. Then, under the influence of
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Published 03 May 2022

Photothermal ablation of murine melanomas by Fe3O4 nanoparticle clusters

  • Xue Wang,
  • Lili Xuan and
  • Ying Pan

Beilstein J. Nanotechnol. 2022, 13, 255–264, doi:10.3762/bjnano.13.20

Graphical Abstract
  • . Photothermal ablation of tumor cells in vitro The dissolution behavior of our finely dispersed Fe3O4 NPCs was confirmed by DLS results (Figure 1d,e). Furthermore, the successful uptake of Fe3O4-based nanoparticles by A375 cells has been verified in our previous report [4]. Thus, to test the therapeutic effect
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Published 22 Feb 2022

Effects of drug concentration and PLGA addition on the properties of electrospun ampicillin trihydrate-loaded PLA nanofibers

  • Tuğba Eren Böncü and
  • Nurten Ozdemir

Beilstein J. Nanotechnol. 2022, 13, 245–254, doi:10.3762/bjnano.13.19

Graphical Abstract
  • heterogeneous matrix instead of a homogeneous one. The addition of PLGA with different concentrations did not cause any changes in the encapsulation efficiency. All PLA/PLGA nanofibers were shown to have favorable encapsulation efficiency (approx. 90%). Dissolution studies In vitro drug release from PLA and PLA
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Published 21 Feb 2022

Relationship between corrosion and nanoscale friction on a metallic glass

  • Haoran Ma and
  • Roland Bennewitz

Beilstein J. Nanotechnol. 2022, 13, 236–244, doi:10.3762/bjnano.13.18

Graphical Abstract
  • surface dissolution at the interface of the two layers. The findings contribute to the understanding of mechanical contacts with metallic glasses under corrosive conditions by exploring the interrelation of microscopic corrosion mechanisms and nanoscale friction. Keywords: atomic force microscopy (AFM
  • layer [18][21][30][31][32]. The outer layer originates from the dissolution of the underlying dense layer and the MG substrate. The characteristics of the friction results reported in Figure 2 and Figure 3 reflect the double layer structure of surface oxide films. A similar correspondence between
  • is recorded on a different spot of the surface. In phosphate buffer, the perfect regularity of the linear dependence of friction on load in the outer layer indicates a similar plowing resistance in different spots and, thus, a laterally uniform outer layer. The dissolution process is uniform on the
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Published 18 Feb 2022
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