Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics

• Mamta Kumari,
• Amitabha Acharya and
• Praveen Thaggikuppe Krishnamurthy

Beilstein J. Nanotechnol. 2023, 14, 912–926, doi:10.3762/bjnano.14.75

• Herceptin® to improve cellular uptake and cytotoxicity in breast cancer cells [41]. Similarly, Rayavarapu et al. conjugated HER2 antibodies on the surface of gold nanoparticles using a noncovalent conjugation method in order to increase intracellular uptake into cancer cells [42]. The adsorption results

N-Heterocyclic carbene-based gold etchants

• Robert B. Chevalier,
• Justin Pantano,
• Matthew K. Kiesewetter and
• Jason R. Dwyer

Beilstein J. Nanotechnol. 2023, 14, 865–871, doi:10.3762/bjnano.14.71

• reported the use of a benzimidazolium gold complex in dichloromethane (DCM) that readily functionalizes gold nanoparticles (AuNPs) in aqueous solution [15][19]. In our work using solution-based approaches to form NHC monolayers on gold thin films, we observed a loss of gold from our substrates. It is

• species (Figure 1) and prepared solutions in THF, DCM, and toluene in which we immersed gold-coated glass slide tokens. We additionally exposed selected solutions to gold nanoparticles in aqueous solutions. Results and Discussion The photograph in Figure 2 shows the loss of gold after immersion for 2 h of

• using the EDS software AZtec from Oxford Instruments (Concord, MA, USA). Gold nanoparticles were synthesized following a modified Fren’s method [33]. Raman spectra were collected using a Snowy Range Instruments Sierra 2.0 spectrometer with laser excitation at 785 nm at a laser power of 74.1 mW and an

Silver nanoparticles loaded on lactose/alginate: in situ synthesis, catalytic degradation, and pH-dependent antibacterial activity

• Nguyen Thi Thanh Tu,
• T. Lan-Anh Vo,
• T. Thu-Trang Ho,
• Kim-Phuong T. Dang,
• Van-Dung Le,
• Phan Nhat Minh,
• Chi-Hien Dang,
• Vinh-Thien Tran,
• Van-Su Dang,
• Tran Thi Kim Chi,
• Hieu Vu-Quang,
• Radek Fajgar,
• Thi-Lan-Huong Nguyen,
• Van-Dat Doan and
• Thanh-Danh Nguyen

Beilstein J. Nanotechnol. 2023, 14, 781–792, doi:10.3762/bjnano.14.64

• 73.9 ± 19.2 nm and 80.2 ± 24.1 nm for AgNPs@Lac/Alg-0.3 and AgNPs@Lac/Alg-0.7, respectively. These findings are consistent with a previous study on the synthesis of gold nanoparticles using this nanocomposite [37]. Figure 4 presents the FTIR spectra of the AgNPs@Lac/Alg nanocomposites. Both spectra

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

• the sensor. A novel electrochemical aptasensor based on Fe MOFs was reported by Song and co-workers [70]. In order to increase the sensor’s sensitivity to the detection of antibiotics, the MOF was further modified using carbon nanofibres and gold nanoparticles using a variety of techniques. In the

Plasmonic nanotechnology for photothermal applications – an evaluation

• A. R. Indhu,
• L. Keerthana and
• Gnanaprakash Dharmalingam

Beilstein J. Nanotechnol. 2023, 14, 380–419, doi:10.3762/bjnano.14.33

Concentration-dependent photothermal conversion efficiency of gold nanoparticles under near-infrared laser and broadband irradiation

• Vikas,
• Raj Kumar and
• Sanjeev Soni

Beilstein J. Nanotechnol. 2023, 14, 205–217, doi:10.3762/bjnano.14.20

• applications. Keywords: broadband irradiation; gold nanoparticles; laser; near-infrared; photothermal conversion efficiency; plasmonics; Introduction Plasmonic photothermal properties of gold nanoparticles (GNPs) are useful for a variety of applications including those in biomedicine, such as drug delivery

• , therapeutics, and diagnostics [1][2][3][4][5]. The interaction of free electrons of gold nanoparticles with electromagnetic fields leads to oscillations of the electrons at plasmonic resonance frequencies. Nonradioactive decay of these oscillations causes the conversion of electromagnetic energy into heat [6

• concentration-dependent photothermal conversion efficiency of various shapes and sizes of gold nanoparticles under broadband irradiation has not been reported to date. In this study, the net temperature rise and the photothermal conversion efficiency of gold nanoparticles are evaluated under irradiation using a

Rapid and sensitive detection of box turtles using an electrochemical DNA biosensor based on a gold/graphene nanocomposite

• Abu Hashem,
• M. A. Motalib Hossain,
• Ab Rahman Marlinda,
• Mohammad Al Mamun,
• Khanom Simarani and
• Mohd Rafie Johan

Beilstein J. Nanotechnol. 2022, 13, 1458–1472, doi:10.3762/bjnano.13.120

• probe using bioinformatics tools, and it was also validated in wet-lab experiments. As a detection platform, a screen-printed carbon electrode (SPCE) enhanced with a nanocomposite containing gold nanoparticles and graphene was used. The morphology of the nanoparticles was analysed by field-emission

• the applications of impedance DNA hybridisation biosensors for the detection of a number of analytes [31][32][33][34]. Nanomaterials may significantly enhance biosensor performance, stability, repeatability, and sensitivity [35][36][37][38][39]. Among various nanomaterials, graphene (Gr) [40] and gold

• nanoparticles (AuNPs) [32] based nanocomposites are well established [41] due to their excellent performance. In particular, self-decorated AuNPs in the honeycomb-structured graphene lattice could facilitate the accommodation of a greater number of recognition probes. In addition, Gr is a nanomaterial with a

Facile preparation of Au- and BODIPY-grafted lipid nanoparticles for synergized photothermal therapy

• Yuran Wang,
• Xudong Li,
• Haijun Chen and
• Yu Gao

Beilstein J. Nanotechnol. 2022, 13, 1432–1444, doi:10.3762/bjnano.13.118

• Synthesis and Function Discovery (Fujian Province University), Fuzhou University, Fuzhou 350116, Fujian, China 10.3762/bjnano.13.118 Abstract Gold nanoparticles with large size exhibit preferable properties for photothermal therapy (PTT). However, the prolonged tissue retention and slow elimination of gold

• effects in comparison to neat gold nanoparticles. To further improve the photothermal activity, we introduced the organic photothermal agent boron dipyrromethene (BODIPY) to Au-LNPs for synergistic PTT. Au- and BODIPY-grafted LNPs (AB-LNPs) were formed by simply mixing Au-LNPs with BODIPY. The BODIPY

• synergistic PTT in the treatment of cancer and other diseases. Keywords: BODIPY; gold nanoparticles; lipid nanoparticles; photothermal therapy; synergism; Introduction Photothermal therapy (PTT) relies on photothermal agents (PTAs) to convert light into heat energy to burn cancer cells. Due to its spatial

Biomimetic chitosan with biocomposite nanomaterials for bone tissue repair and regeneration

• Se-Kwon Kim,
• Sesha Subramanian Murugan,
• Pandurang Appana Dalavi,
• Sebanti Gupta,
• Sukumaran Anil,
• Gi Hun Seong and
• Jayachandran Venkatesan

Beilstein J. Nanotechnol. 2022, 13, 1051–1067, doi:10.3762/bjnano.13.92

• . Further, the developed material shows apatite formation in SBF and it stimulates the growth of MG-63 osteoblast-like cells. In addition, antibacterial activity was discovered against Staphylococcus aureus [85]. Chitosan–gold nanocomposites Gold nanoparticles (AuNPs) have been extensively studied for

• tissue engineering, drug delivery, diagnostic, and bioimaging applications due to its biocompatibility, tuneable size, and ability to cover different kinds of therapeutic agents. Gold nanoparticles control osteoclastic differentiation [113][114][115]. Osteogenic properties of AuNPs were proven by in

• vitro cell interaction with mesenchymal stem cells through the p38 MAPK signalling pathway [17]. Gold nanoparticles show promising results in bone marrow mesenchymal stem cell differentiation towards osteogenic lineages, which might be due to the size and intrinsic factors of AuNPs. Mahmoud et al. (2020

Bioselectivity of silk protein-based materials and their bio-inspired applications

• Hendrik Bargel,
• Vanessa T. Trossmann,
• Christoph Sommer and
• Thomas Scheibel

Beilstein J. Nanotechnol. 2022, 13, 902–921, doi:10.3762/bjnano.13.81

Temperature and chemical effects on the interfacial energy between a Ga–In–Sn eutectic liquid alloy and nanoscopic asperities

• Yujin Han,
• Pierre-Marie Thebault,
• Corentin Audes,
• Xuelin Wang,
• Haiwoong Park,
• Jian-Zhong Jiang and
• Arnaud Caron

Beilstein J. Nanotechnol. 2022, 13, 817–827, doi:10.3762/bjnano.13.72

• exhibits a eutectic between AuSn4 and Sn at 211 °C. A reaction between Au and Sn can thus be ruled out for our experimental conditions. In [23], the authors calculated the surface energy of gold nanoparticles of different shapes. The authors found that the surface energy sharply increases for diameters

Detection and imaging of Hg(II) in vivo using glutathione-functionalized gold nanoparticles

• Gufeng Li,
• Shaoqing Li,
• Rui Wang,
• Min Yang,
• Lizhu Zhang,
• Yanli Zhang,
• Wenrong Yang and
• Hongbin Wang

Beilstein J. Nanotechnol. 2022, 13, 549–559, doi:10.3762/bjnano.13.46

• University, Waurn Ponds, Victoria 3216, Australia 10.3762/bjnano.13.46 Abstract The optical and biological properties of functionalized gold nanoparticles (GNPs) have been widely used in sensing applications. GNPs have a strong binding ability to thiol groups. Furthermore, thiols are used to bind functional

• the fluorescent “ON” form. Keywords: cell imaging; fluorescence probes; glutathione; gold nanoparticles; mercury ions; rhodamine 6G derivatives; Introduction Metal nanoparticles have been widely used in the development and construction of sensor systems and drug carriers due to their excellent

• biocompatibility, large specific surface area, and remarkable photoelectric properties [1][2][3]. Among them, gold nanoparticles (GNPs) have been frequently employed for drug delivery, sensing, imaging, and photodynamic therapy owing to their high extinction coefficient, distinct optical properties, excellent

Impact of device design on the electronic and optoelectronic properties of integrated Ru-terpyridine complexes

• Max Mennicken,
• Sophia Katharina Peter,
• Corinna Kaulen,
• Ulrich Simon and
• Silvia Karthäuser

Beilstein J. Nanotechnol. 2022, 13, 219–229, doi:10.3762/bjnano.13.16

• of gold nanoparticles and contacted by nanoelectrodes. The resulting small-area nanodevices were thoroughly electrically characterized as a function of temperature and light exposure. Differences in the resulting device conductance could be attributed to the device design and the respective transport

• transfer in the Ru-terpyridine complexes used as switching ligands. Finally, our results reveal a superior device performance of nanoparticle-based devices compared to molecular wire devices based on Ru-terpyridine complexes as functional units. Keywords: conductance switching; gold nanoparticles

• the wire-growth protocol developed recently and, thus, to assemble Ru(TP)2-complex wire nanodevices [19]. Additionally, we will use our already successfully applied approach to fabricate nanodevices from ligand-stabilized gold nanoparticles (AuNPs) immobilized between nanoelectrodes [21][22][23][24

A comprehensive review on electrospun nanohybrid membranes for wastewater treatment

• Senuri Kumarage,
• Imalka Munaweera and
• Nilwala Kottegoda

Beilstein J. Nanotechnol. 2022, 13, 137–159, doi:10.3762/bjnano.13.10

• predominant PEMs [13]. Zhang et al. developed nanohybrid PVDF membranes by incorporating zeolite with enhanced thermal and electrochemical performance for lithium-ion batteries [14]. ENHs have also been used as a heterogeneous catalyst in indole synthesis by Savva et al. by incorporating gold nanoparticles

Sputtering onto liquids: a critical review

• Anastasiya Sergievskaya,
• Adrien Chauvin and
• Stephanos Konstantinidis

Beilstein J. Nanotechnol. 2022, 13, 10–53, doi:10.3762/bjnano.13.2

Identifying diverse metal oxide nanomaterials with lethal effects on embryonic zebrafish using machine learning

• Richard Liam Marchese Robinson,
• Haralambos Sarimveis,
• Philip Doganis,
• Xiaodong Jia,
• Marianna Kotzabasaki,
• Christiana Gousiadou,
• Stacey Lynn Harper and
• Terry Wilkins

Beilstein J. Nanotechnol. 2021, 12, 1297–1325, doi:10.3762/bjnano.12.97

Morphology-driven gas sensing by fabricated fractals: A review

• Vishal Kamathe and
• Rupali Nagar

Beilstein J. Nanotechnol. 2021, 12, 1187–1208, doi:10.3762/bjnano.12.88

• –Bi2O3 porous fractal structures contained abundant active sites for the adsorption of carbon dioxide and other VOCs. An improvement of the electron density was attributed to gold nanoparticles. The resulting fractal structures showed excellent sensing properties towards VOCs (100 ppm at room temperature

Assessment of the optical and electrical properties of light-emitting diodes containing carbon-based nanostructures and plasmonic nanoparticles: a review

• Keshav Nagpal,
• Erwan Rauwel,
• Frédérique Ducroquet and
• Protima Rauwel

Beilstein J. Nanotechnol. 2021, 12, 1078–1092, doi:10.3762/bjnano.12.80

• reference. Figure 4a and Figure 4b were adapted from [45] (“Enhanced optical output power of blue light-emitting diodes with quasi-aligned gold nanoparticles“, © 2014 Y. Jin et al., distributed under the terms of the Creative Commons Attribution 2.0 International License, https://creativecommons.org

The role of deep eutectic solvents and carrageenan in synthesizing biocompatible anisotropic metal nanoparticles

• Nabojit Das,
• Akash Kumar and
• Raja Gopal Rayavarapu

Beilstein J. Nanotechnol. 2021, 12, 924–938, doi:10.3762/bjnano.12.69

• nanoparticles, especially rod-shaped gold nanoparticles. The most approved and widely used surfactants for synthesizing anisotropic nanoparticles are quaternary ammonium surfactants with halides (bromide, chloride, or iodide) as counterions. Hexadecyltrimethylammonium bromide (CTAB) is the most commonly used

• the year 2003 [26]. The first work on using DESs as a solvent in synthesizing anisotropic gold nanoparticles was reported in 2008 [27]. The synthesis involved no surfactant or seed in the reaction mixture. Later on, several studies were carried out to synthesize nanomaterials using DESs that embrace

• only at the beginning. To be more specific, carrageenan was used in the synthesis of plasmonic metal nanomaterials much later than DESs. The excellent properties of carrageenan as a stabilizing/capping and a reducing agent was reported in a recent study for gold nanoparticles [32]. To understand the

Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications

• Sepand Tehrani Fateh,
• Lida Moradi,
• Elmira Kohan,
• Michael R. Hamblin and
• Amin Shiralizadeh Dezfuli

Beilstein J. Nanotechnol. 2021, 12, 808–862, doi:10.3762/bjnano.12.64

• (conventional and echogenic), niosomes, nanoemulsions, polymeric nanoparticles, chitosan nanocapsules, dendrimers, hydrogels, nanogels, gold nanoparticles, titania nanostructures, carbon nanostructures, mesoporous silica nanoparticles, fuel-free nano/micromotors. Keywords: smart nanomaterials; sonodynamic

Silver nanoparticles induce the cardiomyogenic differentiation of bone marrow derived mesenchymal stem cells via telomere length extension

• Khosro Adibkia,
• Ali Ehsani,
• Asma Jodaei,
• Ezzatollah Fathi,
• Raheleh Farahzadi and
• Mohammad Barzegar-Jalali

Beilstein J. Nanotechnol. 2021, 12, 786–797, doi:10.3762/bjnano.12.62

• culture medium outside the cells [11]. According to a previous study by Fröhlich et al., the access of Ag-NPs into other organelles depends on the particle size [32]. In the same way, Berry et al. demonstrated that the uptake of NPs is limited by the dimensions of the nuclear pores. Gold nanoparticles (Au

Surface-enhanced Raman scattering of water in aqueous dispersions of silver nanoparticles

• Paulina Filipczak,
• Krzysztof Hałagan,
• Jacek Ulański and
• Marcin Kozanecki

Beilstein J. Nanotechnol. 2021, 12, 497–506, doi:10.3762/bjnano.12.40

• near gold nanoparticles protected by various ligands [38][39]. The results of hydrogen bond dynamics and calculated far-IR spectra showed that a well-defined multilayered structure of water is formed close to the surface of the metal nanoparticle. The stabilization of this structure may be additionally

A review on nanostructured silver as a basic ingredient in medicine: physicochemical parameters and characterization

• Gabriel M. Misirli,
• Kishore Sridharan and
• Shirley M. P. Abrantes

Beilstein J. Nanotechnol. 2021, 12, 440–461, doi:10.3762/bjnano.12.36

• the synthesis of gold nanoparticles in solution using trisodium citrate to reduce AuCl4−. Since then, this methodology is popularly known as the Turkevich method and it has been extended to other metals such as silver [137][138]. Following the same principle, this method is used to reduce Ag+. The

The impact of molecular tumor profiling on the design strategies for targeting myeloid leukemia and EGFR/CD44-positive solid tumors

• Nikola Geskovski,
• Nadica Matevska-Geshkovska,
• Simona Dimchevska Sazdovska,
• Marija Glavas Dodov,
• Kristina Mladenovska and
• Katerina Goracinova

Beilstein J. Nanotechnol. 2021, 12, 375–401, doi:10.3762/bjnano.12.31

• internalization, the chemical sensitivity of the cancer cells, and the efficacy of the gold nanoparticles, using different types of EGFR-expressing NSCLC cancer cell lines. C225-AuNPs showed the largest inhibitory effect on cell growth and cell proliferation when the NSCLC cell line A549 with high EGFR expression

Doxorubicin-loaded gold nanorods: a multifunctional chemo-photothermal nanoplatform for cancer management

• Uzma Azeem Awan,
• Abida Raza,
• Shaukat Ali,
• Rida Fatima Saeed and
• Nosheen Akhtar

Beilstein J. Nanotechnol. 2021, 12, 295–303, doi:10.3762/bjnano.12.24

• -conjugated gold nanorods are highly biocompatible vehicles for sustained drug delivery, reduce cardiotoxicity in vivo, and have high photothermal efficacy [34]. A previous report showed that DOX-loaded tiopronin-coated gold nanoparticles (Au-TIOP-DOX) had a better efficacy in killing cancer cells than free

• DOX [35]. Similarly, a study showed an improved toxicity of DOX-loaded DNA-wrapped gold nanoparticles in drug-resistant cancer cells [36]. Our results are opposite to this study, it might be due to the higher sensitivity of HepG2 cells to DOX, which could induce more toxicity of free drug compared to