Magnetic field-assisted assembly of iron oxide mesocrystals: a matter of nanoparticle shape and magnetic anisotropy

• Julian J. Brunner,
• Marina Krumova,
• Helmut Cölfen and
• Elena V. Sturm (née Rosseeva)

Beilstein J. Nanotechnol. 2019, 10, 894–900, doi:10.3762/bjnano.10.90

• presented a way to form “directed mesocrystals” from superparamagnetic iron oxide nanoparticles using a homogeneous magnetic field. These directed mesocrystals are elongated along the magnetic field and their structure differs from regular self-assembled mesocrystals produced under the same conditions but

Cytotoxicity of doxorubicin-conjugated poly[N-(2-hydroxypropyl)methacrylamide]-modified γ-Fe₂O₃ nanoparticles towards human tumor cells

• Zdeněk Plichta,
• Yulia Kozak,
• Rostyslav Panchuk,
• Viktoria Sokolova,
• Matthias Epple,
• Lesya Kobylinska,
• Pavla Jendelová and
• Daniel Horák

Beilstein J. Nanotechnol. 2018, 9, 2533–2545, doi:10.3762/bjnano.9.236

• toxicity [5][6]. Superparamagnetic iron oxide nanoparticles with well-defined sizes, morphologies and surface are extremely useful in many different areas, in particular in biomedicine. As drug-delivery vehicles, such particles offer significant advantages compared to conventional drug formulations [7][8

• (HPMA-MMAA)-Dox) and compared to control (Figure 11). Both free Dox and γ-Fe2O3@P(HPMA-MMAA)-Dox nanoparticles induced cell death as documented by an increased number of dead cells and decreased number of live cells (Figure 11). Conclusion Superparamagnetic iron oxide nanoparticles can be manipulated

Surface characterization of nanoparticles using near-field light scattering

• Eunsoo Yoo,
• Yizhong Liu,
• Chukwuazam A. Nwasike,
• Sebastian R. Freeman,
• Brian C. DiPaolo,
• Bernardo Cordovez and
• Amber L. Doiron

Beilstein J. Nanotechnol. 2018, 9, 1228–1238, doi:10.3762/bjnano.9.114

• )-coated superparamagnetic iron oxide nanoparticles (PEG-SPIOs) with the synthetic pseudotannin polygallol via interpolymer complexation (IPC). Changes in particle size and zeta potential were indirectly assessed via differences between PEG-SPIOs and IPC-SPIOs in particle velocity and scattering intensity

• , namely uncoated superparamagnetic iron oxide nanoparticles, polyethylene glycol-coated superparamagnetic iron oxide nanoparticles, and interpolymer complex-superparamagnetic iron oxide nanoparticles, were studied for changes in collective size and surface properties using an analysis of particle velocity

• on the waveguide. Superparamagnetic iron oxide nanoparticles (SPIOs) have been extensively studied due to their unique chemical, physical, thermal, and mechanical applications in areas such as cell labeling, tissue repair, drug delivery, magnetic resonance (MR) contrast, and hyperthermia [25][26][27

Methionine-mediated synthesis of magnetic nanoparticles and functionalization with gold quantum dots for theranostic applications

• Arūnas Jagminas,
• Agnė Mikalauskaitė,
• Vitalijus Karabanovas and
• Jūrate Vaičiūnienė

Beilstein J. Nanotechnol. 2017, 8, 1734–1741, doi:10.3762/bjnano.8.174

• Biocompatible superparamagnetic iron oxide nanoparticles (NPs) through smart chemical functionalization of their surface with fluorescent species, therapeutic proteins, antibiotics, and aptamers offer remarkable potential for diagnosis and therapy of disease sites at their initial stage of growth. Such NPs can

Improved biocompatibility and efficient labeling of neural stem cells with poly(L-lysine)-coated maghemite nanoparticles

• Igor M. Pongrac,
• Marina Dobrivojević,
• Lada Brkić Ahmed,
• Michal Babič,
• Miroslav Šlouf,
• Daniel Horák and
• Srećko Gajović

Beilstein J. Nanotechnol. 2016, 7, 926–936, doi:10.3762/bjnano.7.84

• track stem cells by magnetic resonance imaging (MRI) [11], and superparamagnetic iron oxide nanoparticles are particularly used for this purpose [12][13][14][15]. The efficient cellular uptake of nanoparticles, which would not interfere with the labeled cell activities is crucial for reliable cell

Surface coating affects behavior of metallic nanoparticles in a biological environment

• Darija Domazet Jurašin,
• Marija Ćurlin,
• Ivona Capjak,
• Tea Crnković,
• Marija Lovrić,
• Michal Babič,
• Daniel Horák,
• Ivana Vinković Vrček and
• Srećko Gajović

Beilstein J. Nanotechnol. 2016, 7, 246–262, doi:10.3762/bjnano.7.23

• Republic, Heyrovský Sq. 2, 162 06 Prague 6, Czech Republic Institute for Medical Research and Occupational Health, Ksaverska cesta 2, 10 000 Zagreb, Croatia 10.3762/bjnano.7.23 Abstract Silver (AgNPs) and maghemite, i.e., superparamagnetic iron oxide nanoparticles (SPIONs) are promising candidates for new

• currently in use for medical purposes [3], for example silver nanoparticles (AgNPs) and superparamagnetic iron oxide nanoparticles (SPIONs). AgNPs are exploited in medicine for biocidal therapy owing to their antibacterial, antifungal, antiviral, and anti-inflammatory properties. In addition, they attract

• (BSAAgNP), poly(L-lysine) (PLLAgNP), and cetyltrimethylammonium bromide (CTAAgNP). Scale bars are 100 nm. Transmission electron micrographs (TEM) of differently coated superparamagnetic iron oxide nanoparticles: uncoated (UNSPION) and coated with D-mannose (MANSPION) and poly(L-lysine) (PLLSPION). Scale

Caveolin-1 and CDC42 mediated endocytosis of silica-coated iron oxide nanoparticles in HeLa cells

• Nils Bohmer and
• Andreas Jordan

Beilstein J. Nanotechnol. 2015, 6, 167–176, doi:10.3762/bjnano.6.16

• line. Cells were transfected with specific siRNAs against Caveolin-1, Dynamin 2, Flotillin-1, Clathrin, PIP5Kα and CDC42. Knockdown of Caveolin-1 reduces endocytosis of superparamagnetic iron oxide nanoparticles (SPIONs) and silica-coated iron oxide nanoparticles (SCIONs) between 23 and 41%, depending

• nanoparticle species, which are taken up specifically by target cells and exploit their maximum potential. In this study differently modified silica coated superparamagnetic iron oxide nanoparticles (SPIONs) and silica coated iron oxide nanoparticles (SCIONs), which were all comparable in their primary size

• and surface charge, were tested in HeLa cells as a model cell line. To elucidate, which molecular pathways are involved in their endocytosis, well-known endocytotic mechanisms [26][27][28] were inhibited by specific knockdown of key proteins via siRNA (Figure 1). Experimental Superparamagnetic iron

The distribution and degradation of radiolabeled superparamagnetic iron oxide nanoparticles and quantum dots in mice

• Denise Bargheer,
• Artur Giemsa,
• Barbara Freund,
• Markus Heine,
• Christian Waurisch,
• Gordon M. Stachowski,
• Stephen G. Hickey,
• Alexander Eychmüller,
• Jörg Heeren and
• Peter Nielsen

Beilstein J. Nanotechnol. 2015, 6, 111–123, doi:10.3762/bjnano.6.11

• , Germany Institute of Physical Chemistry and Electrochemistry, Technical University of Dresden, Bergstr. 66b, 01069 Dresden, Germany 10.3762/bjnano.6.11 Abstract 51Cr-labeled, superparamagnetic, iron oxide nanoparticles (51Cr-SPIOs) and 65Zn-labeled CdSe/CdS/ZnS-quantum dots (65Zn-Qdots) were prepared

Functionalized polystyrene nanoparticles as a platform for studying bio–nano interactions

• Cornelia Loos,
• Tatiana Syrovets,
• Anna Musyanovych,
• Volker Mailänder,
• Katharina Landfester,
• G. Ulrich Nienhaus and
• Thomas Simmet

Beilstein J. Nanotechnol. 2014, 5, 2403–2412, doi:10.3762/bjnano.5.250

• used superparamagnetic iron oxide nanoparticles. Keywords: amino groups; apoptosis; carboxyl groups; cell proliferation; leukemia cell lines; macrophages; mTOR; polystyrene nanoparticles; Review Applications of polystyrene Polystyrene, one of the most extensively used types of plastic [1], is an

Influence of surface-modified maghemite nanoparticles on in vitro survival of human stem cells

• Michal Babič,
• Daniel Horák,
• Lyubov L. Lukash,
• Tetiana A. Ruban,
• Yurii N. Kolomiets,
• Svitlana P. Shpylova and
• Oksana A. Grypych

Beilstein J. Nanotechnol. 2014, 5, 1732–1737, doi:10.3762/bjnano.5.183

• for the above mentioned purposes [9]. Monosized iron oxide nanoparticles, sometimes called ultra-small superparamagnetic iron oxide nanoparticles, play the dominant role. Quantum dots, gold and, recently, also upconversion nanoparticles are used less frequently. The main advantages of iron oxides

A sonochemical approach to the direct surface functionalization of superparamagnetic iron oxide nanoparticles with (3-aminopropyl)triethoxysilane

• Bashiru Kayode Sodipo and
• Azlan Abdul Aziz

Beilstein J. Nanotechnol. 2014, 5, 1472–1476, doi:10.3762/bjnano.5.160

• Sains Malaysia, 11800 Pulau Pinang, Malaysia 10.3762/bjnano.5.160 Abstract We report a sonochemical method of functionalizing superparamagnetic iron oxide nanoparticles (SPION) with (3-aminopropyl)triethoxysilane (APTES). Mechanical stirring, localized hot spots and other unique conditions generated by

• ; superparamagnetic iron oxide nanoparticles (SPION); Findings Superparamagnetic iron oxide nanoparticles (SPION) have a wide range of applications in biomedical research and development. The main drawbacks of SPION are a high surface energy, van der Waals forces of attraction and dipole to dipole interactions that

PEGylated versus non-PEGylated magnetic nanoparticles as camptothecin delivery system

• Paula M. Castillo,
• Mario de la Mata,
• Maria F. Casula,
• José A. Sánchez-Alcázar and
• Ana P. Zaderenko

Beilstein J. Nanotechnol. 2014, 5, 1312–1319, doi:10.3762/bjnano.5.144

• by means of nano-formulations cover a wide range of organic nanomaterials [11][12][13][14][15][16][17][18][19]. Noticeably, a cyclodextrin-containing polymer–CPT nano-formulation is currently undergoing phase II clinical trials [20]. Superparamagnetic iron oxide nanoparticles (SPION) are particularly

Manipulation of isolated brain nerve terminals by an external magnetic field using D-mannose-coated γ-Fe₂O₃ nano-sized particles and assessment of their effects on glutamate transport

• Tatiana Borisova,
• Natalia Krisanova,
• Arsenii Borуsov,
• Roman Sivko,
• Ludmila Ostapchenko,
• Michal Babic and
• Daniel Horak

Beilstein J. Nanotechnol. 2014, 5, 778–788, doi:10.3762/bjnano.5.90

• showed both negative and positive effects [1]. One of the concerns is that nanoparticles can potentially harm the function of or have toxic effects on human nerve cells owing to their ability to pass through biological membranes [2]. Superparamagnetic iron oxide nanoparticles are considered as promising

• acidification of synaptic vesicles in nerve terminals by using pH-sensitive fluorescent dye acridine orange. Results D-Mannose-coated superparamagnetic γ-Fe2O3 nanoparticles: Synthesis and characterization In this paper, superparamagnetic iron oxide nanoparticles were synthesized by the well-known precipitation

• -fifth of the nanoparticles deposited on the olfactory mucosa can move to the olfactory bulb of rat brain providing a portal for entry into the central nervous system circumventing the blood–brain barrier [25]. In an in vitro model, it was shown that the ability of superparamagnetic iron oxide

Effect of spherical Au nanoparticles on nanofriction and wear reduction in dry and liquid environments

• Dave Maharaj and
• Bharat Bhushan

Beilstein J. Nanotechnol. 2012, 3, 759–772, doi:10.3762/bjnano.3.85

• release of this agent on contact with hydrocarbons is used as an indication of the presence of oil on recovery of the nanoparticles [10]. In contaminant removal, nanocomposites composed of collagen and superparamagnetic iron-oxide nanoparticles (SPIONs) have been investigated. The collagen selectively