Real-time monitoring of calcium carbonate and cationic peptide deposition on carboxylate-SAM using a microfluidic SAW biosensor

• Anna Pohl and
• Ingrid M. Weiss

Beilstein J. Nanotechnol. 2014, 5, 1823–1835, doi:10.3762/bjnano.5.193

• Anna Pohl Ingrid M. Weiss INM – Leibniz Institute for New Materials, Campus D2 2, 66123 Saarbrücken, Germany Saarland University, Campus D2 2, 66123 Saarbrücken, Germany 10.3762/bjnano.5.193 Abstract A microfluidic biosensor with surface acoustic wave technology was used in this study to monitor

• is influenced by the adjacent medium. Phase and amplitude of the propagating wave vary as a function of viscosity changes related to mass deposited on the surface [32]. Advanced microfluidic biosensor technology is based on the propagation of a surface acoustic wave within a thin film [33

• , especially from native shell extracts [40], but even from recombinant sources [41][42]. The aim of the present study was to evaluate the suitability of microfluidic SAW biosensor systems with respect to elucidating the interaction between small biomolecules and calcium carbonate, one of the most common

Analytical development and optimization of a graphene–solution interface capacitance model

• Hediyeh Karimi,
• Rasoul Rahmani,
• Reza Mashayekhi,
• Leyla Ranjbari,
• Amir H. Shirdel,
• Niloofar Haghighian,
• Parisa Movahedi,
• Moein Hadiyan and
• Razali Ismail

Beilstein J. Nanotechnol. 2014, 5, 603–609, doi:10.3762/bjnano.5.71

• these days. Geim, in 2004, demonstrated that the six-membered rings are the basis of all carbon materials in electrochemical biosensor research [7]. The remarkable electrical properties of graphene such as fast electron transport, tunable energy bandgap, high thermal conductivity, and ballistic

DNA origami deposition on native and passivated molybdenum disulfide substrates

• Xiaoning Zhang,
• Masudur Rahman,
• David Neff and
• Michael L. Norton

Beilstein J. Nanotechnol. 2014, 5, 501–506, doi:10.3762/bjnano.5.58

• -pyrenemethylamine and pyrene can prevent immediate DNA origami structural disruption caused by interaction with the MoS2 substrate, the protective effect of the 1-pyrenemethylamine surface layer is much greater than that of pyrene. Conclusion MoS2 has a great potential as a transducer material in future biosensor

A catechol biosensor based on electrospun carbon nanofibers

• Dawei Li,
• Zengyuan Pang,
• Xiaodong Chen,
• Lei Luo,
• Yibing Cai and
• Qufu Wei

Beilstein J. Nanotechnol. 2014, 5, 346–354, doi:10.3762/bjnano.5.39

• carbonization technique. And a polyphenol biosensor was fabricated by blending the obtained CNFs with laccase and Nafion. Raman spectroscopy, Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscope (FE-SEM) were, respectively, employed to investigate the structures and

• morphologies of the CNFs and of the mixtures. Cyclic voltammetry and chronoamperometry were employed to study the electrocatalysis of the catechol biosensor. The results indicated that the sensitivity of the biosensor was 41 µA·mM−1, the detection limit was 0.63 µM, the linear range was 1–1310 µM and the

• response time was within 2 seconds, which excelled most other laccase-based biosensor reported. Furthermore, the biosensor showed good repeatability, reproducibility, stability and tolerance to interferences. This novel biosensor also demonstrated its promising application in detecting catechol in real

Evolution of microstructure and related optical properties of ZnO grown by atomic layer deposition

• Adib Abou Chaaya,
• Roman Viter,
• Mikhael Bechelany,
• Zanda Alute,
• Donats Erts,
• Anastasiya Zalesskaya,
• Kristaps Kovalevskis,
• Vincent Rouessac,
• Valentyn Smyntyna and
• Philippe Miele

Beilstein J. Nanotechnol. 2013, 4, 690–698, doi:10.3762/bjnano.4.78

• interstitials and adsorbed molecular oxygen on the surface of grains. The ultra-thin ZnO ALD films are attractive for optical sensor/biosensor applications due to their high oxygen to zinc ratio and variable optical properties. In addition, the presence of hydroxyl terminals leads to the hydrophilicity of the

• films and improves the immobilization of selected kinds of bio-molecules, thus increasing the suitability for biosensor applications. Experimental Synthesis of ZnO thin films by ALD Diethyl zinc (DEZ) (Zn(CH2CH3)2, 95% purity, CAS: 557-20-0) purchased from Sterm Chemical, a p-type silicon(100) wafer

FTIR nanobiosensors for Escherichia coli detection

• Stefania Mura,
• Gianfranco Greppi,
• Maria Laura Marongiu,
• Pier Paolo Roggero,
• Sandeep P. Ravindranath,
• Lisa J. Mauer,
• Nicoletta Schibeci,
• Francesco Perria,
• Massimo Piccinini,
• Plinio Innocenzi and
• Joseph Irudayaraj

Beilstein J. Nanotechnol. 2012, 3, 485–492, doi:10.3762/bjnano.3.55

• Discussion An optical biosensor was developed for the detection of pathogenic E. coli O157:H7, by using FTIR spectroscopy to provide mid-infrared fingerprints of pathogens present in buffer. The spectroscopic fingerprint of pathogens originates from the various functional groups related to proteins, lipids

• capture of E. coli in less than 30 min. The benefit of this approach is specificity due to the antibodies and the characteristic fingerprint of the pathogens. In this way we demonstrated, as with the new biosensor, through a FTIR measurement and a short time for the analysis, that it is possible to

Self-assembly of octadecyltrichlorosilane: Surface structures formed using different protocols of particle lithography

• ChaMarra K. Saner,
• Kathie L. Lusker,
• Zorabel M. LeJeune,
• Wilson K. Serem and
• Jayne C. Garno

Beilstein J. Nanotechnol. 2012, 3, 114–122, doi:10.3762/bjnano.3.12

• helpful for new applications and developments in the patterning of biomolecules or nanoparticles for optical measurements and biosensor surfaces. The morphology of SAMs or nanostructures of OTS reflects a balance of the interactions that occur between the silane precursor and the silanol groups

Towards multiple readout application of plasmonic arrays

• Dana Cialla,
• Karina Weber,
• René Böhme,
• Uwe Hübner,
• Henrik Schneidewind,
• Matthias Zeisberger,
• Roland Mattheis,
• Robert Möller and
• Jürgen Popp

Beilstein J. Nanotechnol. 2011, 2, 501–508, doi:10.3762/bjnano.2.54

• more detailed information, SERS was employed as a readout technique for the same biosensor. The detected mean value SERS spectra, shown in Figure 2B, are dominated by contributions of the Cy3.5 label (see therefore the reference spectrum in [29]). The detected background signal, which can be attributed

• binding efficiency of the dye labeled target DNA and moreover the SERS signal was decreased for the noncomplementary case (Figure 2C). Thus, the established biosensor allowed the distinction between a complementary and a noncomplementary binding of target DNA through both a fluorescence and SERS detection

Biomimetics inspired surfaces for drag reduction and oleophobicity/philicity

• Bharat Bhushan

Beilstein J. Nanotechnol. 2011, 2, 66–84, doi:10.3762/bjnano.2.9

• superhydrophobic, self-cleaning, low adhesion, and drag reduction surfaces Drag reduction in fluid flow is of interest in various commercial applications. These include transportation vehicles and micro/nanofluidics based biosensor applications [3]. To reduce pressure drop and volume loss in micro/nanochannels

Magnetic nanoparticles for biomedical NMR-based diagnostics

• Huilin Shao,
• Tae-Jong Yoon,
• Monty Liong,
• Ralph Weissleder and
• Hakho Lee

Beilstein J. Nanotechnol. 2010, 1, 142–154, doi:10.3762/bjnano.1.17

• enabled parallel and sensitive measurements to be made from small volume samples. Thus, the DMR technology is a highly attractive platform for portable, low-cost, and efficient biomolecular detection within a biomedical setting. Keywords: biosensor; diagnostics; magnetic nanoparticle; microfluidics

• for DMR biosensing [13][40]. However, these systems lack the capability for performing multiplexed measurements, and require large sample volumes (>100 μL) to achieve accurate measurements. Chip-NMR biosensor To overcome the limitations of conventional detectors and to address the need for fast

Electrochemical behavior of dye-linked L-proline dehydrogenase on glassy carbon electrodes modified by multi-walled carbon nanotubes

• Haitao Zheng,
• Leyi Lin,
• Yosuke Okezaki,
• Ryushi Kawakami,
• Haruhiko Sakuraba,
• Toshihisa Ohshima,
• Keiichi Takagi and
• Shin-ichiro Suye

Beilstein J. Nanotechnol. 2010, 1, 135–141, doi:10.3762/bjnano.1.16

• -proline. Because electroactive ferrocene groups were used as the electron mediator, the above sensors should operate at an applied potential of +0.45 V to satisfy the redox reaction of ferrocene. In order to improve the sensitivity of electrochemical L-proline biosensor at lower applied potentials, multi