Label-free highly sensitive probe detection with novel hierarchical SERS substrates fabricated by nanoindentation and chemical reaction methods

• Jingran Zhang,
• Tianqi Jia,
• Yongda Yan,
• Li Wang,
• Peng Miao,
• Yimin Han,
• Xinming Zhang,
• Guangfeng Shi,
• Yanquan Geng,
• Zhankun Weng,
• Daniel Laipple and
• Zuobin Wang

Beilstein J. Nanotechnol. 2019, 10, 2483–2496, doi:10.3762/bjnano.10.239

• food are detected by using many methods including gas chromatography, gas chromatography mass spectrometry, and liquid chromatography. These methods suffer from the need of preprocessing and long analysis time. However, SERS technology is a new option to detect pesticide residues in a fast, simple, and

Mobility of charge carriers in self-assembled monolayers

• Zhihua Fu,
• Tatjana Ladnorg,
• Hartmut Gliemann,
• Alexander Welle,
• Asif Bashir,
• Michael Rohwerder,
• Qiang Zhang,
• Björn Schüpbach,
• Andreas Terfort and
• Christof Wöll

Beilstein J. Nanotechnol. 2019, 10, 2449–2458, doi:10.3762/bjnano.10.235

• . Time-of-flight secondary ion mass spectrometry (TOF-SIMS) measurements were carried out in a TOF-SIMS 5 device (ION-TOF GmbH, Münster, Germany). The spectrometry was performed in static SIMS mode (primary ion beam dose < 2 × 1011 ions/cm2) with Bi3+ primary ions at 25 keV. Spectra were calibrated on

Long-term entrapment and temperature-controlled-release of SF₆ gas in metal–organic frameworks (MOFs)

• Hana Bunzen,
• Andreas Kalytta-Mewes,
• Leo van Wüllen and
• Dirk Volkmer

Beilstein J. Nanotechnol. 2019, 10, 1851–1859, doi:10.3762/bjnano.10.180

•  1). The analysis revealed a gradual mass loss between 150–500 °C. When heated above 500 °C, a second mass loss was observed which corresponded to the framework decomposition. By utilizing mass spectrometry, we analyzed the gaseous products that were released during sample heating. We recorded that

• decomposition, a study of temperature-induced gas release followed by mass spectrometry was carried out. In this measurement only signals corresponding to the SF6 fragments (such as SF5· and SF4·) [41] and no signals of its thermal decomposition products [42] could be detected, confirming that the gas release

• phase by mass spectrometry (Figure S12 in Supporting Information File 1). As expected, upon adding the acid to the reaction vessel, the framework decomposed and an immediate evolution of gas bubbles was observed. The SF6 release could be followed by mass spectrometry; however, a precise quantification

Biocatalytic oligomerization-induced self-assembly of crystalline cellulose oligomers into nanoribbon networks assisted by organic solvents

• Yuuki Hata,
• Yuka Fukaya,
• Toshiki Sawada,
• Masahito Nishiura and
• Takeshi Serizawa

Beilstein J. Nanotechnol. 2019, 10, 1778–1788, doi:10.3762/bjnano.10.173

• structure of the products was analyzed by 1H NMR spectroscopy and MALDI–TOF mass spectrometry. The NMR spectra of the representative products showed proton signals for cellulose oligomers (Figure 5). In addition, the mass spectra further revealed the successful synthesis of cellulose oligomers (Figure 6

• robustness. Experimental Materials αG1P disodium salt n-hydrate and 40% sodium deuteroxide (NaOD)/deuterium oxide (D2O) solution were purchased from Wako Pure Chemical Industries. ProteoMass MALDI–MS standard, 1% trifluoroacetic acid, MeCN used for preparing MALDI–TOF mass spectrometry samples, 2,5

• centrifugation (20,400g)/redispersion cycles to remove more than 99.999% of the soluble fraction of the reaction mixtures. For MALDI–TOF mass spectrometry, the purified product dispersions were stored at 4 °C until use. For the quantification of the insoluble products, a volume of the purified product

Synthesis of nickel/gallium nanoalloys using a dual-source approach in 1-alkyl-3-methylimidazole ionic liquids

• Ilka Simon,
• Julius Hornung,
• Juri Barthel,
• Jörg Thomas,
• Maik Finze,
• Roland A. Fischer and
• Christoph Janiak

Beilstein J. Nanotechnol. 2019, 10, 1754–1767, doi:10.3762/bjnano.10.171

• samples of copper, silver and gold at 50 eV and 10 eV pass energy and comparison with reference values. Spectra were obtained with an Al Kα X-ray source, using C 1s as a reference for the binding energy [50]. Gas chromatography–mass spectrometry (GC–MS) data were recorded on a Thermo Finnigan Trace DSQ

Serum type and concentration both affect the protein-corona composition of PLGA nanoparticles

• Katrin Partikel,
• Robin Korte,
• Dennis Mulac,
• Hans-Ulrich Humpf and
• Klaus Langer

Beilstein J. Nanotechnol. 2019, 10, 1002–1015, doi:10.3762/bjnano.10.101

• assay, zeta potential measurements, and liquid chromatography–mass spectrometry/mass spectrometry (LC–MS/MS). Additionally, the time-dependent cell interaction of PLGA NPs in the absence or presence of a preformed protein corona was assessed by in vitro incubation experiments with the human liver cancer

• complexes from excess serum proteins we used sodium dodecylsulfate polyacrylamide gel electrophoresis (SDS-PAGE), zeta potential measurements, and liquid chromatography–mass spectrometry/mass spectrometry (LC–MS/MS) to study the composition of adsorbed proteins in detail. A quantitative analysis of corona

• carried out overnight under slight shaking (37 °C, 900 rpm). Finally, the reaction was stopped by adjusting the pH to below 6 with glacial acetic acid and the samples were filled up to a total volume of 2 mL with ultrapure water for the further experimental procedure. Sample preparation for mass

Structural and optical properties of penicillamine-protected gold nanocluster fractions separated by sequential size-selective fractionation

• Xiupei Yang,
• Zhengli Yang,
• Fenglin Tang,
• Jing Xu,
• Maoxue Zhang and
• Martin M. F. Choi

Beilstein J. Nanotechnol. 2019, 10, 955–966, doi:10.3762/bjnano.10.96

• -molecule impurities. Based on the results from the mass spectrometry and thermogravimetric analysis, the average composition of the four fractions can be represented by Au38(SR)18, Au28(SR)15, Au18(SR)12, and Au11(SR)8, respectively. This indicates that the SSSP separation is mainly dependent on the core

• synthesized penicillamine-protected AuNCs in aqueous medium. The product was isolated and purified by sequential size-selective precipitation (SSSP) and characterized by mass spectrometry (MS) [20]. In order to further explore the different structures and properties of NCs of different sizes after

• chemical shift at 1.42, 1.51, 1.73, 1.79, 3.77 and 3.98 ppm (Figure 5, spectrum 7), indicating that the main disulfide with a small amount of free ligand and gold(I) complex are separated from other fractions. The assignments are also confirmed by mass spectrometry (vide infra). That is to say that not

In situ AFM visualization of Li–O₂ battery discharge products during redox cycling in an atmospherically controlled sample cell

• Kumar Virwani,
• Younes Ansari,
• Khanh Nguyen,
• Francisco José Alía Moreno-Ortiz,
• Jangwoo Kim,
• Maxwell J. Giammona,
• Ho-Cheol Kim and
• Young-Hye La

Beilstein J. Nanotechnol. 2019, 10, 930–940, doi:10.3762/bjnano.10.94

• surface are still visible. We speculate that under these conditions the cell dies due to the depletion of O2 as a result of slow transport through the electrolyte limited by diffusion in contrast with conventional differential electrochemical mass spectrometry (DEMS) cells where oxygen is bubbled through

Polymorphic self-assembly of pyrazine-based tectons at the solution–solid interface

• Achintya Jana,
• Puneet Mishra and
• Neeladri Das

Beilstein J. Nanotechnol. 2019, 10, 494–499, doi:10.3762/bjnano.10.50

• pyrazine ring at the para-positions, making an angle of 180° between the two binding sites, giving it a linear shape (Figure 1). Details of the synthesis of the molecule, and its characterization by means of FTIR, 1H and 13C NMR, mass spectrometry, and single crystal X-ray diffraction are provided in

Reduced graphene oxide supported C₃N₄ nanoflakes and quantum dots as metal-free catalysts for visible light assisted CO₂ reduction

• Md Rakibuddin and
• Haekyoung Kim

Beilstein J. Nanotechnol. 2019, 10, 448–458, doi:10.3762/bjnano.10.44

• prepared metal-free GCN-5 is highly stable and can be reused for the photoreduction tests. The photoreduction of CO2 to HCHO is also verified by gas chromatography mass spectrometry (GC–MS). A sample is examined for GC analysis after 4 h of photoirradiation with GCN-5 under identical conditions, and the

• absorbance spectra were measured using a UV–visible spectrophotometer (Thermo Fisher Scientific). Gas chromatography coupled with mass spectrometry (GC–MS) was carried out on an Agilent 7890A instrument with both a thermal conductivity detector and a flame ionization detector and using helium as a carrier

Relation between thickness, crystallite size and magnetoresistance of nanostructured La_1−xSr_xMn_yO_3±δ films for magnetic field sensors

• Rasuole Lukose,
• Valentina Plausinaitiene,
• Milita Vagner,
• Nerija Zurauskiene,
• Skirmantas Kersulis,
• Virgaudas Kubilius,
• Karolis Motiejuitis,
• Birute Knasiene,
• Voitech Stankevic,
• Zita Saltyte,
• Martynas Skapas,
• Algirdas Selskis and
• Evaldas Naujalis

Beilstein J. Nanotechnol. 2019, 10, 256–261, doi:10.3762/bjnano.10.24

• SU70). The structural analysis was performed in cross section geometry by TEM (FEI Tecnai G2 F20 X-TWIN). The elemental composition analysis was performed by inductively coupled plasma high-resolution mass spectrometry (ICP-MS) - Thermo Scientific Element2, where the films were totally dissolved in 2

Mechanism of silica–lysozyme composite formation unravelled by in situ fast SAXS

• Tomasz M. Stawski,
• Daniela B. van den Heuvel,
• Rogier Besselink,
• Dominique J. Tobler and
• Liane G. Benning

Beilstein J. Nanotechnol. 2019, 10, 182–197, doi:10.3762/bjnano.10.17

• water to remove excess lysozyme and salts followed by a 2nd drying step at 40 °C. The amount of lysozyme associated with the composites was quantified by determining the total carbon content in solids by mass spectrometry (DELTAplusXL ThermoFisher) with a Carlo-Erba NC2500. From these analyses the

Scanning probe microscopy for energy-related materials

• Rüdiger Berger,
• Benjamin Grévin,
• Philippe Leclère and
• Yi Zhang

Beilstein J. Nanotechnol. 2019, 10, 132–134, doi:10.3762/bjnano.10.12

• major topic in our daily life. Jonathan Op de Beeck and co-workers identify the ionic processes occurring inside Li-ion composites in order to understand the impact on the entire battery cell [9]. In particular, the authors combine cAFM and secondary-ion mass spectrometry to correlate the presence of

Time-resolved universal temperature measurements using NaYF₄:Er³⁺,Yb³⁺ upconverting nanoparticles in an electrospray jet

• Kristina Shrestha,
• Arwa A. Alaulamie,
• Ali Rafiei Miandashti and
• Hugh H. Richardson

Beilstein J. Nanotechnol. 2018, 9, 2916–2924, doi:10.3762/bjnano.9.270

• -invasively image and measure temperatures in complex systems such as in vivo imaging, cellular biological systems and matrices, whole-blood samples, and electrospray jets used in mass spectrometry [1]. Optical thermometers using UCNPs are well suited for these applications because near-IR excitation of the

Accurate control of the covalent functionalization of single-walled carbon nanotubes for the electro-enzymatically controlled oxidation of biomolecules

• Naoual Allali,
• Veronika Urbanova,
• Mathieu Etienne,
• Xavier Devaux,
• Martine Mallet,
• Brigitte Vigolo,
• Jean-Joseph Adjizian,
• Chris P. Ewels,
• Sven Oberg,
• Alexander V. Soldatov,
• Edward McRae,
• Yves Fort,
• Manuel Dossot and
• Victor Mamane

Beilstein J. Nanotechnol. 2018, 9, 2750–2762, doi:10.3762/bjnano.9.257

• core line and setting adventitious carbon signal (C sp3 signal) to 284.6 eV. For thermogravimetric analyses coupled to mass spectrometry (TGA-MS) experiments, 5–6 mg of the sample powder were placed in an alumina crucible. The TGA-MS instrument included a Setaram Setsys evolution 1750 Thermal

• temperature associated with departure of some chemical groups attached to SWCNT sidewalls. Mass spectrometry channels used to show the departure peaks of the cyclopentadienyl group and its main fragments at m/z = 66 and m/z = 39. Inset: the departure peak of the iron atoms of the ferrocene groups. Raman data

Cytotoxicity of doxorubicin-conjugated poly[N-(2-hydroxypropyl)methacrylamide]-modified γ-Fe₂O₃ nanoparticles towards human tumor cells

• Zdeněk Plichta,
• Yulia Kozak,
• Rostyslav Panchuk,
• Viktoria Sokolova,
• Matthias Epple,
• Lesya Kobylinska,
• Pavla Jendelová and
• Daniel Horák

Beilstein J. Nanotechnol. 2018, 9, 2533–2545, doi:10.3762/bjnano.9.236

• Bruker DPX 300 spectrometer (Billerica; MA, USA) and a Perkin Elmer PARAGON 1000 PC spectrometer (Bucks, UK), respectively. Gas and HPLC SEC chromatography was performed on a Clarus 500 Perkin Elmer gas chromatograph (Shelton, CT, USA) and a Shimadzu HPLC chromatograph (Kyoto, Japan) equipped with a mass

• spectrometry and UV–vis, RID, or DAWN 8 MALS detectors (Wyatt Technology; Santa Barbara, CA, USA), respectively. Agilent DB-35MS GC column (30 m × 0.25 mm id, 0.25 µm film; helium carrier gas) and Chromolith RP-18 e HPLC column (100 mm × 4.6 mm id) with a flow rate of 5 mL acetonitrile/water mixture per min

Non-agglomerated silicon–organic nanoparticles and their nanocomplexes with oligonucleotides: synthesis and properties

• Asya S. Levina,
• Marina N. Repkova,
• Nadezhda V. Shikina,
• Zinfer R. Ismagilov,
• Svetlana A. Yashnik,
• Dmitrii V. Semenov,
• Yulia I. Savinovskaya,
• Natalia A. Mazurkova,
• Inna A. Pyshnaya and
• Valentina F. Zarytova

Beilstein J. Nanotechnol. 2018, 9, 2516–2525, doi:10.3762/bjnano.9.234

• coupled plasma mass spectrometry (ICP-MS). The experimental Si/P value (10.9) showed a reasonable correlation with the calculated data (10.0). The atomic force microscopy (AFM) image of the Si–NH2 nanoparticles was not obtained in a satisfactory quality because of the very small size of the particles

• monomers (Glen Research, USA). The optical absorption of oligonucleotides and their derivatives was measured on a Shimadzu U-1800 spectrophotometer (Shimadzu, Japan). Inductively coupled plasma mass spectrometry (ICP-MS) was performed using an Agilent 7700 ICP MS (USA) spectrometer. The IR spectrum of the

• stirred at this temperature for 15 h and then cooled to the room temperature. The concentration of the product (0.46 M) was evaluated by inductively coupled plasma mass spectrometry (ICP-MS) on an Agilent 7700 ICP-MS spectrometer or by titration of the amino groups with hydrochloric acid. The yield of the

Phosphorus monolayer doping (MLD) of silicon on insulator (SOI) substrates

• Noel Kennedy,
• Ray Duffy,
• Luke Eaton,
• Dan O’Connell,
• Scott Monaghan,
• Shane Garvey,
• James Connolly,
• Chris Hatem,
• Justin D. Holmes and
• Brenda Long

Beilstein J. Nanotechnol. 2018, 9, 2106–2113, doi:10.3762/bjnano.9.199

• the Si substrate. MLD-doped 66 nm SOI was further examined using secondary ion mass spectrometry (SIMS) to attain a more detailed view of total dopant distribution in the substrate, which is complementary to previous measurements of active carrier concentrations through ECV. Data shown in Figure 7

• under neutral conditions. Controlled-voltage etching was carried out with step widths of 2–5 nm. Secondary ion mass spectrometry data was acquired on a Phi Adept 1010 using a 0.5–1.0 keV Cs+ bombardment with negative ion detection. X-ray photoelectron spectroscopy XPS spectra were acquired on an Oxford

• under inert conditions. Secondary ion mass spectrometry analysis of a P-MLD-doped 66 nm silicon on insulator substrate. Blue line: P concentration, red line: O concentration. Hall effect data of 66 nm and 13 nm MLD-doped SOI. Supporting Information Comprehensive Hall effect analysis data and ECV of

Defect formation in multiwalled carbon nanotubes under low-energy He and Ne ion irradiation

• Santhana Eswara,
• Jean-Nicolas Audinot,
• Brahime El Adib,
• Maël Guennou,
• Tom Wirtz and
• Patrick Philipp

Beilstein J. Nanotechnol. 2018, 9, 1951–1963, doi:10.3762/bjnano.9.186

• secondary ion mass spectrometry experiments as described elsewhere, which leads to a modified octagon and pole-pieces [59]. The bright-field (BF) TEM images were recorded in the He+ and Ne+ craters using Gatan on-axis CCD camera with 2k × 2k pixel array (Figure 8). Raman spectroscopy was done prior to TEM

Sulfur-, nitrogen- and platinum-doped titania thin films with high catalytic efficiency under visible-light illumination

• Boštjan Žener,
• Lev Matoh,
• Giorgio Carraro,
• Bojan Miljević and
• Romana Cerc Korošec

Beilstein J. Nanotechnol. 2018, 9, 1629–1640, doi:10.3762/bjnano.9.155

• dispersions [45]. The prepared samples were analyzed using thermogravimetric analysis–differential scanning calorimetry–mass spectrometry (TGA-DSC-MS), X-ray diffraction spectroscopy (XRD), specific surface area measurements via Brunauer–Emmett–Teller method (BET), X-ray photoelectron spectroscopy (XPS

• durations of illumination with visible light. The concentration of the dye was calculated using the Beer–Lambert law. Thermogravimetric analysis–differential scanning calorimetry–mass spectrometry (TGA-DSC-MS) curves of different xerogel samples: a) REF, b) S1 and c) S3. X-ray diffraction patterns for

Nanoscale electrochemical response of lithium-ion cathodes: a combined study using C-AFM and SIMS

• Jonathan Op de Beeck,
• Nouha Labyedh,
• Alfonso Sepúlveda,
• Valentina Spampinato,
• Alexis Franquet,
• Thierry Conard,
• Philippe M. Vereecken,
• Wilfried Vandervorst and
• Umberto Celano

Beilstein J. Nanotechnol. 2018, 9, 1623–1628, doi:10.3762/bjnano.9.154

• established nanoscale analysis techniques namely conductive atomic force microscopy (C-AFM) and secondary ion mass spectrometry (SIMS). We present a platform to study Li-ion composites with nanometer resolution that allows one to sense a multitude of key characteristics including structural, electrical and

• indicated. Keywords: all-solid-state microbatteries (ASB); conductive atomic force microscopy (C-AFM); Li-ion kinetics; secondary ion mass spectrometry (SIMS); 3D thin-film batteries; Findings Conventional Li-ion battery technology is undergoing continuous improvements in order to fulfil the increasing

• conductive atomic force microscopy (C-AFM) and secondary ion mass spectrometry (SIMS). As model systems, we focus on LiMn2O4 (LMO) as cathode material [7] deposited by wet electrodeposition (thickness 260 nm) and RF-sputtered (thickness 100 nm) and compare their properties on a local (sub-100 nm) scale. In

Absence of free carriers in silicon nanocrystals grown from phosphorus- and boron-doped silicon-rich oxide and oxynitride

• Daniel Hiller,
• Julian López-Vidrier,
• Keita Nomoto,
• Michael Wahl,
• Wolfgang Bock,
• Tomáš Chlouba,
• František Trojánek,
• Sebastian Gutsch,
• Margit Zacharias,
• Dirk König,
• Petr Malý and
• Michael Kopnarski

Beilstein J. Nanotechnol. 2018, 9, 1501–1511, doi:10.3762/bjnano.9.141

• measurements were post-annealed in the same furnace in pure H2 gas at 450 °C for 1 h to enable the passivation of dangling bond defects [18]. For electrical measurements, MOS capacitors were processed by thermal evaporation of Al-contacts. Molecular Cs+ secondary ion mass spectrometry (MCs+-SIMS [19]; Cameca

Effect of annealing treatments on CeO₂ grown on TiN and Si substrates by atomic layer deposition

• Silvia Vangelista,
• Rossella Piagge,
• Satu Ek and
• Alessio Lamperti

Beilstein J. Nanotechnol. 2018, 9, 890–899, doi:10.3762/bjnano.9.83

• distribution as in [26]. Time-of-flight secondary ion mass spectrometry (ToF-SIMS) investigation of the compositional depth profile of the CeO2/TiN/Si and CeO2/Si structures has been performed by means of a Cs+ ion beam (energy of 0.5 keV, ion current 38.0 nA) sputtering a 200 μm × 200 μm area, and a Ga+ ion

Electron interactions with the heteronuclear carbonyl precursor H₂FeRu₃(CO)₁₃ and comparison with HFeCo₃(CO)₁₂: from fundamental gas phase and surface science studies to focused electron beam induced deposition

• Ragesh Kumar T P,
• Paul Weirich,
• Lukas Hrachowina,
• Marc Hanefeld,
• Ragnar Bjornsson,
• Helgi Rafn Hrodmarsson,
• Sven Barth,
• D. Howard Fairbrother,
• Michael Huth and
• Oddur Ingólfsson

Beilstein J. Nanotechnol. 2018, 9, 555–579, doi:10.3762/bjnano.9.53

• ), reflection-absorption IR spectroscopy (RAIRS), and/or high-resolution electron energy loss spectroscopy (HREELS), while mass spectrometry has been used to identify gas phase species generated as a result of electron irradiation. As such the surface science experiments represent an increased level of

• monitored in situ by X-ray photoelectron spectroscopy (XPS) and mass spectrometry. Figure 9 shows the evolution of the O 1s, Fe 2p and Ru 3d/C 1s XPS regions of a nanometer-thick film of H2FeRu3(CO)13 adsorbed onto a gold substrate at 213 K, plotted as a function of increasing electron dose. Area analysis

Green synthesis of fluorescent carbon dots from spices for in vitro imaging and tumour cell growth inhibition

• Nagamalai Vasimalai,
• Vânia Vilas-Boas,
• Juan Gallo,
• María de Fátima Cerqueira,
• Mario Menéndez-Miranda,
• José Manuel Costa-Fernández,
• Lorena Diéguez,
• Begoña Espiña and
• María Teresa Fernández-Argüelles

Beilstein J. Nanotechnol. 2018, 9, 530–544, doi:10.3762/bjnano.9.51

• involved in the toxicity in both cell types. Black pepper C-dots showed the most noticeable effect on the LN-229 cells. Thus, in order to elucidate whether the black pepper C-dots effect might be attributed to the presence of molecules existing in the starting material, mass spectrometry measurements of

• , Germany) and the C-dots samples were prepared on a glass substrate. Fourier transform infrared (FTIR) spectra were recorded using a Perkin Elmer Spectra 100 FTIR Spectrometer (Perkin Elmer, USA). Electrospray ionization coupled to quantitative time of flight mass spectrometry measurements were performed