Recent progress in cancer cell membrane-based nanoparticles for biomedical applications

• Qixiong Lin,
• Yueyou Peng,
• Yanyan Wen,
• Xiaoqiong Li,
• Donglian Du,
• Weibin Dai,
• Wei Tian and
• Yanfeng Meng

Beilstein J. Nanotechnol. 2023, 14, 262–279, doi:10.3762/bjnano.14.24

• resection. Due to the lack of effective therapeutic targets and its insensitivity and resistance to drugs, TNBC has a high possibility of recurrence and a poor prognosis [63][64]. A type of multifunctional NPs encapsulated with the membrane of 4T1 breast cancer cells was prepared to counteract the

• anticancer effects [76]. After QT was delivered to tumor tissue by the active targeting ability of the membrane, the sensitivity to radiotherapy was effectively improved, and a strong anticancer effect was exerted under X-ray irradiation [76]. Gong et al. designed a pH-responsive multifunctional biomimetic

Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer

• Filip Gorachinov,
• Fatima Mraiche,
• Diala Alhaj Moustafa,
• Ola Hishari,
• Yomna Ismail,
• Jensa Joseph,
• Maja Simonoska Crcarevska,
• Marija Glavas Dodov,
• Nikola Geskovski and
• Katerina Goracinova

Beilstein J. Nanotechnol. 2023, 14, 240–261, doi:10.3762/bjnano.14.23

• agents. Precision oncology research to identify targetable biomarkers and optimize tumor homing agents, hand in hand with designing multifunctional and multistage nanocarriers that respond to the inherent heterogeneity of the tumors, may resolve the challenges of inadequate tumor localization, improve

• targeting motifs, multifunctional and multistage nanomicelles and polymer nanoparticles, and nanostructured lipid nanocarriers, combined with precision oncology research to identify additional targetable biomarkers, have emerged. Some have been applied in the co-delivery of clinically relevant combinations

• targeting efficacy of nanomedicines. Various solutions have been proposed to improve mononuclear phagocytic system (MPS) evasion, extravasation at the tumor site, and diffusion through the dense collagen matrix of the solid tumors. Biomimetic, multifunctional, and multistage targeted nanoscale delivery

Bioselectivity of silk protein-based materials and their bio-inspired applications

• Hendrik Bargel,
• Vanessa T. Trossmann,
• Christoph Sommer and
• Thomas Scheibel

Beilstein J. Nanotechnol. 2022, 13, 902–921, doi:10.3762/bjnano.13.81

• tissue formation. Conversely, the adhesion and presence of microbes interferes with important multicellular processes of tissue development. Therefore, tailoring bioselective, biologically active, and multifunctional materials for biomedical applications is a modern focus of biomaterial research

• interacting with members of the integrin family of cell surface proteins. However, fibronectin is a multifunctional adhesion molecule, also binding to other protein constituents of the ECM such as fibrin, collagen, and heparin [24]. Thus, fibronectin is involved in several physiological events such as

• RGD and collagen to an antimicrobial polymeric multilayer composed of dextran sulfate and chitosan [103]. One way to achieve bioselective, biocompatible, and multifunctional materials for biomedical applications is the utilization of natural protein materials shown to accomplish the desired properties

Zinc oxide nanostructures for fluorescence and Raman signal enhancement: a review

• Ioana Marica,
• Fran Nekvapil,
• Maria Ștefan,
• Cosmin Farcău and
• Alexandra Falamaș

Beilstein J. Nanotechnol. 2022, 13, 472–490, doi:10.3762/bjnano.13.40

• ) spectrum of ZnO also consists of a broad band emission in the visible region, which is generally assigned to defect levels [86][87]. The combination of ZnO nanostructures with metal nanoparticles can result in new optical features and the development of a new class of multifunctional optical components

Micro- and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritis

• Zahra Nabizadeh,
• Mahmoud Nasrollahzadeh,
• Hamed Daemi,
• Mohamadreza Baghaban Eslaminejad,
• Ali Akbar Shabani,
• Mehdi Dadashpour,
• Majid Mirmohammadkhani and
• Davood Nasrabadi

Beilstein J. Nanotechnol. 2022, 13, 363–389, doi:10.3762/bjnano.13.31

A comprehensive review on electrospun nanohybrid membranes for wastewater treatment

• Senuri Kumarage,
• Imalka Munaweera and
• Nilwala Kottegoda

Beilstein J. Nanotechnol. 2022, 13, 137–159, doi:10.3762/bjnano.13.10

Sputtering onto liquids: a critical review

• Anastasiya Sergievskaya,
• Adrien Chauvin and
• Stephanos Konstantinidis

Beilstein J. Nanotechnol. 2022, 13, 10–53, doi:10.3762/bjnano.13.2

Polarity in cuticular ridge development and insect attachment on leaf surfaces of Schismatoglottis calyptrata (Araceae)

• Venkata A. Surapaneni,
• Tobias Aust,
• Thomas Speck and
• Marc Thielen

Beilstein J. Nanotechnol. 2021, 12, 1326–1338, doi:10.3762/bjnano.12.98

• .12.98 Abstract The plant cuticle is a multifunctional barrier that separates the organs of the plant from the surrounding environment. Cuticular ridges are microscale wrinkle-like cuticular protrusions that occur on many flower and leaf surfaces. These microscopic ridges can help against pest insects by

Morphology-driven gas sensing by fabricated fractals: A review

• Vishal Kamathe and
• Rupali Nagar

Beilstein J. Nanotechnol. 2021, 12, 1187–1208, doi:10.3762/bjnano.12.88

Progress and innovation of nanostructured sulfur cathodes and metal-free anodes for room-temperature Na–S batteries

• Marina Tabuyo-Martínez,
• Bernd Wicklein and
• Pilar Aranda

Beilstein J. Nanotechnol. 2021, 12, 995–1020, doi:10.3762/bjnano.12.75

Self-assembly of Eucalyptus gunnii wax tubules and pure ß-diketone on HOPG and glass

• Miriam Anna Huth,
• Axel Huth and
• Kerstin Koch

Beilstein J. Nanotechnol. 2021, 12, 939–949, doi:10.3762/bjnano.12.70

• multifunctional wax coating on their surfaces made of branched ß-diketone tubules. ß-diketone tubules have a different size, shape, and chemical composition than the well-described nonacosanol tubules of the superhydrophobic leaves of lotus (Nelumbo nucifera). Until now the formation process of ß-diketone tubules

• interface, covers all aerial non-lignified parts of higher plants [1]. It is an extracellular membrane of epidermal cells, consisting of a matrix of the polymer cutin and a mixture of hydrophobic compounds, the cuticular waxes [2][3]. This interface is a multifunctional surface optimized by evolution to

Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications

• Sepand Tehrani Fateh,
• Lida Moradi,
• Elmira Kohan,
• Michael R. Hamblin and
• Amin Shiralizadeh Dezfuli

Beilstein J. Nanotechnol. 2021, 12, 808–862, doi:10.3762/bjnano.12.64

• free radicals [150]. Masuda et al. proposed that there is a relation between the quality and quantity of free radical formation and the frequency of the US applied in the presence of MBs [151]. The combination of free-radical-generating components and other materials could lead to multifunctional

Recent progress in magnetic applications for micro- and nanorobots

• Ke Xu,
• Shuang Xu and
• Fanan Wei

Beilstein J. Nanotechnol. 2021, 12, 744–755, doi:10.3762/bjnano.12.58

• method to complete medical tasks with the optimal trajectory of controllable movement of MNRs in cardiovascular system was proposed. Some multiferroic nanomaterials exhibit ferromagnetism and antiferromagnetism by adjusting electricity and magnetism. A variety of multifunctional devices can be prepared

Nanogenerator-based self-powered sensors for data collection

• Yicheng Shao,
• Maoliang Shen,
• Yuankai Zhou,
• Xin Cui,
• Lijie Li and
• Yan Zhang

Beilstein J. Nanotechnol. 2021, 12, 680–693, doi:10.3762/bjnano.12.54

• intelligence. Wang et al. proposed a hydrophobic polytetrafluoroethylene film and sponge-like graphene/polydimethylsiloxane composite material to prepare a multifunctional self-powered sensor [51]. The sensor can infer the performance of the material through the difference in the output of the electrical

The impact of molecular tumor profiling on the design strategies for targeting myeloid leukemia and EGFR/CD44-positive solid tumors

• Nikola Geskovski,
• Nadica Matevska-Geshkovska,
• Simona Dimchevska Sazdovska,
• Marija Glavas Dodov,
• Kristina Mladenovska and
• Katerina Goracinova

Beilstein J. Nanotechnol. 2021, 12, 375–401, doi:10.3762/bjnano.12.31

• sensitivity of the cancer cells against the antineoplastic agents, (ii) functionalized nanoscale systems carrying anticancer agents that target multiple receptors, or (iii) other multifunctional approaches involving gene therapy for receptor knockdown administered with anticancer agents in targeted

• development and survival have fostered the parallel development of multifunctional bioactive nanomedicines capable of attacking multiple targets, which hold potential to overcome current deficiencies of targeted therapy. Targeting strategies with innovative ligands for nanoparticle surface engineering

Doxorubicin-loaded gold nanorods: a multifunctional chemo-photothermal nanoplatform for cancer management

• Uzma Azeem Awan,
• Abida Raza,
• Shaukat Ali,
• Rida Fatima Saeed and
• Nosheen Akhtar

Beilstein J. Nanotechnol. 2021, 12, 295–303, doi:10.3762/bjnano.12.24

• study was to fabricate biocompatible multifunctional drug-loaded nanoscale moieties for co-therapy (chemo-photothermal therapy) with maximum efficacy and minimum side effects. Herein, we report in vitro anticancerous effects of doxorubicin (DOX) loaded on gold nanorods coated with the polyelectrolyte

• site [11]. Nanotechnology provides a means to overcome these hurdles as nanocarriers, which improve the pharmacological properties of free drugs, contribute to enhanced therapeutic efficacy in physiological environment [12]. Nanocarriers as multifunctional tumor targeting and therapeutic agents exhibit

• nanocomplex compared to free DOX, herein, we have used the same strategy as described in an earlier report [18] to design a multifunctional PSS-coated GNRs-based nano-platform that facilitate chemotherapy by delivering anticancerous drug at the site of action. DOX release with precise temporal and spatial

Differences in surface chemistry of iron oxide nanoparticles result in different routes of internalization

• Barbora Svitkova,
• Vlasta Zavisova,
• Veronika Nemethova,
• Martina Koneracka,
• Miroslava Kretova,
• Filip Razga,
• Monika Ursinyova and
• Alena Gabelova

Beilstein J. Nanotechnol. 2021, 12, 270–281, doi:10.3762/bjnano.12.22

• eligible for the targeted delivery of the drug-loaded particles to the tumor mass via an external magnetic field [2]. Furthermore, MNPs are promising biosensors [3] and antimicrobial tools [4], and they play an important role in the development of multifunctional theranostics to combat cancer [5]. MNPs are

Paper-based triboelectric nanogenerators and their applications: a review

• Jing Han,
• Nuo Xu,
• Yuchen Liang,
• Mei Ding,
• Junyi Zhai,
• Qijun Sun and
• Zhong Lin Wang

Beilstein J. Nanotechnol. 2021, 12, 151–171, doi:10.3762/bjnano.12.12

• paper-based 3D foldable device submitted to a direct laser patterning method, which can convert ink-soaked paper substrates to multifunctional carbide/graphene (MCG) composites [92]. The composites have shown good conductivity even after repeated mechanical bending and folding tests. Moreover, the laser

PEG/PEI-functionalized single-walled carbon nanotubes as delivery carriers for doxorubicin: synthesis, characterization, and in vitro evaluation

• Shuoye Yang,
• Zhenwei Wang,
• Yahong Ping,
• Yuying Miao,
• Yongmei Xiao,
• Lingbo Qu,
• Lu Zhang,
• Yuansen Hu and
• Jinshui Wang

Beilstein J. Nanotechnol. 2020, 11, 1728–1741, doi:10.3762/bjnano.11.155

• attributed to their good dispersibility and comparably higher affinity to tumor cells due to the difunctionalization. In summary, the PEG- and PEI-conjugated CNTs may be used as novel nanocarriers and the findings will contribute to the rational design of multifunctional delivery vehicles for anticancer

Antimicrobial metal-based nanoparticles: a review on their synthesis, types and antimicrobial action

• Matías Guerrero Correa,
• Fernanda B. Martínez,
• Cristian Patiño Vidal,
• Camilo Streitt,
• Juan Escrig and
• Carol Lopez de Dicastillo

Beilstein J. Nanotechnol. 2020, 11, 1450–1469, doi:10.3762/bjnano.11.129

• properties in comparison to commercial TiO2 NPs [38]. Youssef et al. (2018) developed a biocomposite in the nanoscale with 2 wt % of TiO2 NPs which prevented mold growth on a cheese surface during an antimicrobial assay [3]. Nickel oxide nanoparticles have a multifunctional nature with interesting

Triboelectric nanogenerator based on Teflon/vitamin B1 powder for self-powered humidity sensing

• Liangyi Zhang,
• Huan Li,
• Yiyuan Xie,
• Jing Guo and
• Zhiyuan Zhu

Beilstein J. Nanotechnol. 2020, 11, 1394–1401, doi:10.3762/bjnano.11.123

• , TENGs should be seamlessly integrated and fabricated using a simple process, particularly regarding multifunctional sensing applications. In the present study, a novel Teflon/vitamin B1 powder based triboelectric nanogenerator (TVB-TENG) is proposed. Vitamin B1 is an essential water-soluble vitamin

• approximately CN¥ 0.5. An oscilloscope (probe: 100 MΩ) was used to measure the voltage across the external load (a variable resistor) and a high-precision multifunctional electronic scale, with an accuracy of 0.001 g, was used to measure the required amount of vitamin B1 powder. Results and Discussion As shown

Transient coating of γ-Fe₂O₃ nanoparticles with glutamate for its delivery to and removal from brain nerve terminals

• Konstantin Paliienko,
• Artem Pastukhov,
• Michal Babič,
• Daniel Horák,
• Olga Vasylchenko and
• Tatiana Borisova

Beilstein J. Nanotechnol. 2020, 11, 1381–1393, doi:10.3762/bjnano.11.122

• transient glutamate biocoating can be useful for multifunctional theranostics. Keywords: blood plasma; brain nerve terminals; glutamate biocoating; maghemite (γ-Fe2O3) nanoparticles; protein biocorona; Introduction Glutamate is a main fast excitatory neurotransmitter in the central nervous system. Normal

Revealing the local crystallinity of single silicon core–shell nanowires using tip-enhanced Raman spectroscopy

• Marius van den Berg,
• Ardeshir Moeinian,
• Arne Kobald,
• Yu-Ting Chen,
• Anke Horneber,
• Steffen Strehle,
• Alfred J. Meixner and
• Dai Zhang

Beilstein J. Nanotechnol. 2020, 11, 1147–1156, doi:10.3762/bjnano.11.99

• serving as multifunctional platforms for field-effect transistors [4][5][6], photovoltaic devices [7][8][9][10] and miniaturized chemical sensors [5][11][12]. A key element for many of those devices are high-quality nanometer-scale semiconductor junctions, such as pn-junctions that ensure the intended

Photothermally active nanoparticles as a promising tool for eliminating bacteria and biofilms

• Mykola Borzenkov,
• Piersandro Pallavicini,
• Angelo Taglietti,
• Laura D’Alfonso,
• Maddalena Collini and
• Giuseppe Chirico

Beilstein J. Nanotechnol. 2020, 11, 1134–1146, doi:10.3762/bjnano.11.98

• irradiated gold nanocrosses attached to the bacteria was effective in eliminating and preventing bacterial regrowth. By combining the magnetic and optical properties of Fe3O4 and gold nanoparticles, respectively, multifunctional nanohybrids based on Fe3O4@Au (i.e., magnetite nanoparticles decorated with gold

• nanoparticles with a magnetic Fe3O4 shell, displaying strong magnetic responsiveness and tunable plasmonic properties (absorption maximum in the 480–825 nm range), were prepared as a multifunctional tool for bacterial disinfection [72]. The prepared nanoparticles displayed enhanced photothermal stability, high

• terms of their photothermally induced antibacterial activity [80][81]. Currently, there are still a few studies relating the application of the photothermal effect on CuS to eradicate bacteria. A multifunctional core/satellite nanostructure was engineered by decorating CuS nanoparticles onto the surface

Gram-scale synthesis of splat-shaped Ag–TiO₂ nanocomposites for enhanced antimicrobial properties

• Mohammad Jaber,
• Asim Mushtaq,
• Kebiao Zhang,
• Jindan Wu,
• Dandan Luo,
• Zihan Yi,
• M. Zubair Iqbal and
• Xiangdong Kong

Beilstein J. Nanotechnol. 2020, 11, 1119–1125, doi:10.3762/bjnano.11.96

• , surface functionalities, high surface-to-volume ratio and tunable physiochemical properties are unique characteristics that make nanomaterials promising for biomedical applications [6][7]. Multifunctional nanomaterials have been developed to decontaminate surfaces infested with infectious pathogens

• which have significant antimicrobial activity against Gram-positive and Gram-negative bacteria [16][17]. Importantly, Ag and TiO2 NPs have been reported to be less toxic to humans [2][18][19][20]. In comparison to single NPs, the nanocomposites have advantages in terms of multifunctional use