Microstructural and plasmonic modifications in Ag–TiO₂ and Au–TiO₂ nanocomposites through ion beam irradiation

• Venkata Sai Kiran Chakravadhanula,
• Yogendra Kumar Mishra,
• Venkata Girish Kotnur,
• Devesh Kumar Avasthi,
• Thomas Strunskus,
• Vladimir Zaporotchenko,
• Dietmar Fink,
• Lorenz Kienle and
• Franz Faupel

Beilstein J. Nanotechnol. 2014, 5, 1419–1431, doi:10.3762/bjnano.5.154

• significant research interest due their multifunctional properties appropriate for various applications ranging from solar cells to targeted drug delivery [1][2][3][4]. The plasmonic properties of the nanocomposite films mainly depend upon the type of nanoparticles (Au or Ag), their morphology and the

Model systems for studying cell adhesion and biomimetic actin networks

• Dorothea Brüggemann,
• Johannes P. Frohnmayer and
• Joachim P. Spatz

Beilstein J. Nanotechnol. 2014, 5, 1193–1202, doi:10.3762/bjnano.5.131

• synthetic cells will certainly pave the way for model systems with tailored properties, which can also play an important role in targeted drug delivery or the development of novel implant materials. Schematic view of active integrin molecules linking the ECM to the actin cytoskeleton. The heads of the

Nanodiamond-DGEA peptide conjugates for enhanced delivery of doxorubicin to prostate cancer

• Amanee D Salaam,
• Patrick Hwang,
• Roberus McIntosh,
• Hadiyah N Green,
• Ho-Wook Jun and
• Derrick Dean

Beilstein J. Nanotechnol. 2014, 5, 937–945, doi:10.3762/bjnano.5.107

• targeted drug delivery systems can provide an avenue to overcome these issues. Nanodiamonds (ND), in particular, have been researched over the past five years for use in various drug delivery systems but minimal work has been done that incorporates targeting capability. In this study, a novel targeted drug

• ; doxorubicin; nanodiamond; prostate cancer; targeted drug delivery; Introduction Prostate cancer is the most frequently diagnosed malignancy in men [1]. Typically the disease is slow growing, but in some cases it progresses to an aggressively metastatic state. When prostate cancer becomes metastatic, the

• carriers [17][18][19][20]. NDs have been used as a vehicle for targeted drug delivery platforms [16][21][22][23][24][25]. NDs have already been shown to improve the efficacy of DOX for treating breast cancers and gliomas [26][27][28]. Even though pre-clinical work has been done with targeted NDs, the

Manipulation of isolated brain nerve terminals by an external magnetic field using D-mannose-coated γ-Fe₂O₃ nano-sized particles and assessment of their effects on glutamate transport

• Tatiana Borisova,
• Natalia Krisanova,
• Arsenii Borуsov,
• Roman Sivko,
• Ludmila Ostapchenko,
• Michal Babic and
• Daniel Horak

Beilstein J. Nanotechnol. 2014, 5, 778–788, doi:10.3762/bjnano.5.90

• candidates to increase the efficiency of targeted drug delivery not because of the possibility to attach antibodies to their surfaces, but also because of the possibly to use external magnetic guidance [3]. Superparamagnetism is an important characteristic because when the external magnetic field is taken

In vitro toxicity and bioimaging studies of gold nanorods formulations coated with biofunctional thiol-PEG molecules and Pluronic block copolymers

• Tianxun Gong,
• Douglas Goh,
• Malini Olivo and
• Ken-Tye Yong

Beilstein J. Nanotechnol. 2014, 5, 546–553, doi:10.3762/bjnano.5.64

• the NIR region so that heat is generated to damage cells and tissues. This property renders them useful for photothermal therapy and imaging of cancer [7][8]. In addition, the AuNRs surface can be functionalized with ligands for targeted drug delivery to support cancer therapy in vitro and in vivo [9

Plasma-assisted synthesis and high-resolution characterization of anisotropic elemental and bimetallic core–shell magnetic nanoparticles

• M. Hennes,
• A. Lotnyk and
• S. G. Mayr

Beilstein J. Nanotechnol. 2014, 5, 466–475, doi:10.3762/bjnano.5.54

• as powerful nanotools in many areas of biology, biophysics and medicine [1]. Possible applications include their use as contrast agents for cell tracking via magnetic resonance imaging (MRI) [2], as colloidal mediators in cancer therapy (hyperthermia) [3] or as nanocarriers for targeted drug delivery

Effect of spherical Au nanoparticles on nanofriction and wear reduction in dry and liquid environments

• Dave Maharaj and
• Bharat Bhushan

Beilstein J. Nanotechnol. 2012, 3, 759–772, doi:10.3762/bjnano.3.85

• include, but are not limited to, their use in targeted drug delivery and chemical sensors in the identification of oil, removal of contaminants and enhanced oil recovery (EOR). Au, iron oxide, polymer and silica nanoparticles have been studied in targeted drug delivery [3][4][5][6][7][8]. In cancer

• diffuses into the diseased cell resulting in cell death. Several factors need to be considered for the successful use of nanoparticles in targeted drug delivery. Biological barriers, including physical surfaces and the reticulo-endothelial system (RES), which detects and sequesters blood-borne particles

Characterization of protein adsorption onto FePt nanoparticles using dual-focus fluorescence correlation spectroscopy

• Pauline Maffre,
• Karin Nienhaus,
• Faheem Amin,
• Wolfgang J. Parak and
• G. Ulrich Nienhaus

Beilstein J. Nanotechnol. 2011, 2, 374–383, doi:10.3762/bjnano.2.43

• subcellular compartments. Consequently, they hold great promise as tools for biomedical applications such as targeted drug delivery [1] or gene therapy [2]. However, NPs often exhibit properties distinctly different from those of the bulk material. For example, an enhanced surface reactivity may be observed