Radiosensitizing properties of dual-functionalized carbon nanostructures loaded with temozolomide

• Radmila Milenkovska,
• Nikola Geskovski,
• Dushko Shalabalija,
• Ljubica Mihailova,
• Petre Makreski,
• Dushko Lukarski,
• Igor Stojkovski,
• Maja Simonoska Crcarevska and
• Kristina Mladenovska

Beilstein J. Nanotechnol. 2025, 16, 229–251, doi:10.3762/bjnano.16.18

• ]. These findings are supported by several publications in which CNs were evaluated as potential drug carriers or inherent drugs for brain targeting and (synergistic) treatment of Alzheimer disease [20], Parkinson disease [21], and brain tumors [22][23][24][25], and as agents for the detection of brain

Recent advances in photothermal nanomaterials for ophthalmic applications

• Jiayuan Zhuang,
• Linhui Jia,
• Chenghao Li,
• Rui Yang,
• Jiapeng Wang,
• Wen-an Wang,
• Heng Zhou and
• Xiangxia Luo

Beilstein J. Nanotechnol. 2025, 16, 195–215, doi:10.3762/bjnano.16.16

• PAI contrast agents [195][196]. Gold nanorods [197], gold nanostars [198], hollow gold nanocages [199], chains of gold nanoparticles [200], and ultraminiature chain-like gold nanoparticle clusters [201] have been used for the detection of ocular structures such as retinal blood vessels, choroidal

Modeling and simulation of carbon-nanocomposite-based gas sensors

• Roopa Hegde,
• Punya Prabha V,
• Shipra Upadhyay and
• Krishna S B

Beilstein J. Nanotechnol. 2025, 16, 90–96, doi:10.3762/bjnano.16.9

• , its composites, and their application in electrochemical sensors have been discussed [6][7][8]. There are research contributions on pristine graphene and ammonia gas sensors for detection of very low ammonia content [9]. The thin-film sensor fabricated on polyethylenimine- (PEI) functionalized SWCNTs

• showed high sensitivity towards strong electron-withdrawing molecules for NO2 gas detection [10]. To simulate gas adsorption in COMSOL Multiphysics for a gas sensor, several adsorption models can be employed depending on the physical and chemical behavior of the sensor. Commonly used models include the

Characterization of ZnO nanoparticles synthesized using probiotic Lactiplantibacillus plantarum GP258

• Prashantkumar Siddappa Chakra,
• Aishwarya Banakar,
• Shriram Narayan Puranik,
• Vishwas Kaveeshwar,
• C. R. Ravikumar and
• Devaraja Gayathri

Beilstein J. Nanotechnol. 2025, 16, 78–89, doi:10.3762/bjnano.16.8

• procedure was used. Denaturation at 96 °C for 5 min was preceded by denaturation at the same temperature for 30 s, hybridization at 50 °C for 30 s for thirty cycles, with a final elongation step at 60 °C for 90 s. Later, the amplicons were sequenced using the ABI 3130 Genetic Analyzer sequence detection

Instance maps as an organising concept for complex experimental workflows as demonstrated for (nano)material safety research

• Benjamin Punz,
• Maja Brajnik,
• Joh Dokler,
• Jaleesia D. Amos,
• Litty Johnson,
• Katie Reilly,
• Anastasios G. Papadiamantis,
• Amaia Green Etxabe,
• Lee Walker,
• Diego S. T. Martinez,
• Steffi Friedrichs,
• Klaus M. Weltring,
• Nazende Günday-Türeli,
• Claus Svendsen,
• Christine Ogilvie Hendren,
• Mark R. Wiesner,
• Martin Himly,
• Iseult Lynch and
• Thomas E. Exner

Beilstein J. Nanotechnol. 2025, 16, 57–77, doi:10.3762/bjnano.16.7

• functionalised SiO2 nanomaterials under varying conditions. They also compared artificial and real allergen mixtures by applying genuine detection assays suitable for allergenic molecules in vitro and assessed two recently developed in silico protein corona prediction tools regarding the results from

Advanced atomic force microscopy techniques V

• Philipp Rahe,
• Ilko Bald,
• Nadine Hauptmann,
• Regina Hoffmann-Vogel,
• Harry Mönig and
• Michael Reichling

Beilstein J. Nanotechnol. 2025, 16, 54–56, doi:10.3762/bjnano.16.6

• . Khachartryan et al. highlight the strength of cantilever displacement detection with a Michelson-type fibre interferometer and provide a model for interferometric signal generation [4]. The interferometer response is slightly nonlinear under typical NC-AFM working conditions, while a large cantilever

• . Grévin et al. further push the boundaries of the detection by implementing an open-loop variant of KPFM which accesses the spectrum of a time-periodic surface potential [5]. By exploiting a double heterodyne frequency mixing effect, they can selectively transfer each harmonic component to the second

• cantilever eigenmode, which is particularly relevant when generating the time-periodic potential by optical or electrical pumping. With this development, the authors could present the detection of modulated components that are below the detection limit of other KPFM measurement modes. Da Lisca et al

A nanocarrier containing carboxylic and histamine groups with dual action: acetylcholine hydrolysis and antidote atropine delivery

• Elina E. Mansurova,
• Andrey A. Maslennikov,
• Anna P. Lyubina,
• Alexandra D. Voloshina,
• Irek R. Nizameev,
• Marsil K. Kadirov,
• Anzhela A. Mikhailova,
• Polina V. Mikshina,
• Albina Y. Ziganshina and
• Igor S. Antipin

Beilstein J. Nanotechnol. 2025, 16, 11–24, doi:10.3762/bjnano.16.2

• to use. Elution was carried out using 0.05 M K2HPO4, pH 7.4, at a flow rate of 0.5 mL·min−1 and a column temperature of 40 °C with refractive index detection on a 1260 Infinity detector (Agilent, Germany) at an optical unit temperature of 35 °C. Polyacrylic acid standards of 240, 5, and 1.8 kDa (Alfa

Orientation-dependent photonic bandgaps in gold-dust weevil scales and their titania bioreplicates

• Norma Salvadores Farran,
• Limin Wang,
• Primoz Pirih and
• Bodo D. Wilts

Beilstein J. Nanotechnol. 2025, 16, 1–10, doi:10.3762/bjnano.16.1

• detection pathway, we obtained reciprocal space images (Figure 3b). The domains oriented close to the {111} direction produced reciprocal space images with a greenish or yellowish central hexagon shape (Figure 3b II,VII), while the domains close to {110} orientation produced images with two partially

Liver-targeting iron oxide nanoparticles and their complexes with plant extracts for biocompatibility

• Shushanik A. Kazaryan,
• Seda A. Oganian,
• Gayane S. Vardanyan,
• Anatolie S. Sidorenko and
• Ashkhen A. Hovhannisyan

Beilstein J. Nanotechnol. 2024, 15, 1593–1602, doi:10.3762/bjnano.15.125

• , biochemistry, biophysics, and other disciplines within biology and medicine [1][2][3][4][5]. The development of nanotechnology has provided resources for various applications in the medical field, leading to significant advances in diagnosis, biological detection, therapy, and drug delivery [6][7][8][9]. An

• colorimetric method using the stable radical 2,2-diphenyl-1-picrylhydrazyl (DPPH, Alfa Aeser, Germany) at 30 °C. Optical density (OD) detection was carried out at 517 nm wavelength (UV-VIS 18, MRC, Israel), and ARA was estimated according to the following equation: where ODc is the optical density of the

Facile synthesis of size-tunable L-carnosine-capped silver nanoparticles and their role in metal ion sensing and catalytic degradation of p-nitrophenol

• Akash Kumar,
• Ridhima Chadha,
• Abhishek Das,
• Nandita Maiti and
• Rayavarapu Raja Gopal

Beilstein J. Nanotechnol. 2024, 15, 1576–1592, doi:10.3762/bjnano.15.124

• , and Raman spectroscopy, as well as EDX and XRD revealed controlled aggregation, successful capping, and crystalline growth of the ʟ-car-AgNPs. The ʟ-car-AgNPs exhibited promising sensing capabilities with limits of detection of 141.79 ppb (1.2 μM) for Cd2+, 131.33 ppb (0.63 μM) for Pb2+, 215.35 ppb

• -car-AgNPs for both heavy metal ion detection and catalytic degradation of P-NP, indicating their suitability for environmental monitoring and remediation applications. Further optimization and research are needed to expand their environmental applications and to understand their interaction mechanisms

• biomagnification [1]. Similarly, organic pollutants such as p-nitrophenol (P-NP), from agricultural and industrial processes, are of significant concern because of their toxicity and resistance to degradation [2]. Consequently, detection and removal of these contaminants have become crucial for environmental

Electrochemical nanostructured CuBTC/FeBTC MOF composite sensor for enrofloxacin detection

• Thi Kim Ngan Nguyen,
• Tien Dat Doan,
• Huy Hieu Luu,
• Hoang Anh Nguyen,
• Thi Thu Ha Vu,
• Quang Hai Tran,
• Ha Tran Nguyen,
• Thanh Binh Dang,
• Thi Hai Yen Pham and
• Mai Ha Hoang

Beilstein J. Nanotechnol. 2024, 15, 1522–1535, doi:10.3762/bjnano.15.120

• /bjnano.15.120 Abstract A novel electrochemical sensor for the detection of enrofloxacin (ENR) in aqueous solutions has been developed using a carbon paste electrode modified with a mixture of metal-organic frameworks (MOFs) of CuBTC and FeBTC. These MOFs were successfully synthesized via a solvothermal

• significantly enhanced the electrochemical response of ENR, increasing the signal by more than ten times compared to the unmodified electrode. Under optimal analytical conditions, the sensor exhibited three dynamic ranges for ENR detection, that is, 0.005 to 0.100 µM, 0.1 to 1.0 µM, and 1 to 13 µM, with

• coefficients of determination of 0.9990, 0.9954, and 0.9992, respectively, depending on the accumulation duration. The sensor achieved a low detection limit of 3 nM and demonstrated good reproducibility, with a relative standard deviation of 3.83%. Furthermore, the sensor demonstrated effective performance in

Lithium niobate on insulator: an emerging nanophotonic crystal for optimized light control

• Midhun Murali,
• Amit Banerjee and
• Tanmoy Basu

Beilstein J. Nanotechnol. 2024, 15, 1415–1426, doi:10.3762/bjnano.15.114

• , and spin–photon entanglement), and detection (involving single-photon detectors). Keywords: integrated photonics; lithium niobate; photonic bandgap; photonic crystal; titanium dioxide; Introduction One-dimensional photonic crystals (PhCs) are electromagnetic media in which materials are periodically

Out-of-plane polarization induces a picosecond photoresponse in rhombohedral stacked bilayer WSe₂

• Guixian Liu,
• Yufan Wang,
• Zhoujuan Xu,
• Zhouxiaosong Zeng,
• Lanyu Huang,
• Cuihuan Ge and
• Xiao Wang

Beilstein J. Nanotechnol. 2024, 15, 1362–1368, doi:10.3762/bjnano.15.109

• intrinsic photoresponse time of approximately 3 ps. The ultrafast response time remains consistent across varying detection powers, demonstrating environmental stability and highlighting the potential in optoelectronic applications. Our study presents an effective strategy for enhancing the response time of

• photoelectric detection. Experimental Device fabrication The 2D materials, WSe2 and graphene, were obtained from high-quality bulk crystals using the mechanical exfoliation method. The monolayer WSe2 nanoflakes were exfoliated onto a transparent polydimethylsiloxane (PDMS) film, selected based on optical

Investigation of Hf/Ti bilayers for the development of transition-edge sensor microcalorimeters

• Victoria Y. Safonova,
• Anna V. Gordeeva,
• Anton V. Blagodatkin,
• Dmitry A. Pimanov,
• Anton A. Yablokov and
• Andrey L. Pankratov

Beilstein J. Nanotechnol. 2024, 15, 1353–1361, doi:10.3762/bjnano.15.108

• , for example, for the detection of dark matter, as single-photon detectors (X-ray, visible, and infrared ranges) [1], and the detection of individual excimers [2]. One of the new applications is the detection of the recoil energy of 4He atoms evaporated from a superfluid condensate (helium II). This

• generally also means a shorter thermal response time, allowing the detector to respond more quickly to small temperature changes. Second, the active area is reduced, which allows for a more efficient detection of a useful signal because of the higher energy density and, therefore, a higher signal-to-noise

Hymenoptera and biomimetic surfaces: insights and innovations

• Vinicius Marques Lopez,
• Carlo Polidori and
• Rhainer Guillermo Ferreira

Beilstein J. Nanotechnol. 2024, 15, 1333–1352, doi:10.3762/bjnano.15.107

• tiny structures belong to two main functional types. They are either mechanosensory and belong to the peripheral nervous system or they have no sensing role and serve to prevent wetting of, for example, wings and legs [41][42][43][44]. Other functions include the detection of airflow patterns, for

• the result of co-evolution of these traits with ecological requirements [56][92][93][94]. Furthermore, they are essentially in both intra- and interspecific communications [95][96][97]. These antennal sensors have inspired the development of devices for the detection of volatile compounds, which have

Nanoarchitectonics with cetrimonium bromide on metal nanoparticles for linker-free detection of toxic metal ions and catalytic degradation of 4-nitrophenol

• Akash Kumar and
• Raja Gopal Rayavarapu

Beilstein J. Nanotechnol. 2024, 15, 1312–1332, doi:10.3762/bjnano.15.106

• nanoparticle-based systems capable of efficient detection and degradation. However, conventional approaches utilizing strong capping agents like cetrimonium bromide (CTAB) on nanoparticles lead to limitations due to the rigid nature of CTAB. This restricts its utility in heavy metal detection and 4-NP

• degradation, requiring additional surface modifications using linker molecules, thereby increasing process complexity and cost. To overcome these limitations, there is a critical need for the development of an easy-to-use, dual-functional, linker-free nanosystem capable of simultaneous detection of heavy

• metals and efficient degradation of 4-NP. For enabling linker-free/ligand-free detection of heavy metal ions and catalytic degradation of 4-NP, CTAB was engineered as a versatile capping agent on gold and silver nanoparticles. Various factors, including nanoparticle characteristics such as shape, size

Mn-doped ZnO nanopowders prepared by sol–gel and microwave-assisted sol–gel methods and their photocatalytic properties

• Cristina Maria Vlăduț,
• Crina Anastasescu,
• Silviu Preda,
• Oana Catalina Mocioiu,
• Simona Petrescu,
• Jeanina Pandele-Cusu,
• Dana Culita,
• Veronica Bratan,
• Ioan Balint and
• Maria Zaharescu

Beilstein J. Nanotechnol. 2024, 15, 1283–1296, doi:10.3762/bjnano.15.104

• /mc space group. No other phases, including Mn-based compounds, were detected within the detection limits of the instrument, suggesting that the dopant has been incorporated into the zincite lattice. The patterns of the two samples, SG and MW, are very similar, with slightly more intense diffraction

Dual-functionalized architecture enables stable and tumor cell-specific SiO₂NPs in complex biological fluids

• Iris Renata Sousa Ribeiro,
• Raquel Frenedoso da Silva,
• Romênia Ramos Domingues,
• Adriana Franco Paes Leme and
• Mateus Borba Cardoso

Beilstein J. Nanotechnol. 2024, 15, 1238–1252, doi:10.3762/bjnano.15.100

• equipment (Malvern Instruments Ltd., UK – detection angle of 173° and laser wavelength of 633 nm). For DLS measurements, NPs were dispersed in MilliQ water (1.0 mg·mL–1). To determine the zeta potential, the NPs were diluted in 10 Mm of phosphate buffer at a concentration of 1.0 mg·mL–1. All measurements

• -ZW-NH2 samples was visualized. The low concentration of the functional groups was probably not significant enough for detection. The SiO2NPs-ZW-FO showed a less negative zeta potential value than the previous functionalization steps, which is opposite to what was expected after adding folate [38][41

Realizing active targeting in cancer nanomedicine with ultrasmall nanoparticles

• André F. Lima,
• Giselle Z. Justo and
• Alioscka A. Sousa

Beilstein J. Nanotechnol. 2024, 15, 1208–1226, doi:10.3762/bjnano.15.98

• therapeutic target for MM [161]. Based on this, the Gd construct was utilized for the detection of malignant plasma cells in MM using magnetic resonance imaging (MRI). Competitive cell-binding assays confirmed the maintenance of antibody specificity after conjugation to usNPs. The resulting targeted usNPs

• -noise ratio for MM detection, surpassing levels achievable with other clinically approved imaging modalities. As early as 30 min post-administration, animals treated with the targeted usNPs demonstrated a ≈3-fold improvement in SNR for plasmacytomas in the spine. Song et al. synthesized AuNCs protected

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

• Shakhzodjon Uzokboev,
• Khojimukhammad Akhmadbekov,
• Ra’no Nuritdinova,
• Salah M. Tawfik and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

• disease diagnosis, quick detection of diverse drugs and chemicals, and long-term monitoring [9]. In the recent decade, sensor technology has seen breakthroughs thanks to the usage of nanomaterials with superior physicochemical properties [10][11][12][13]. Nowadays, the development of sensors based on

• several hours for results. The development of compact and portable miniaturized sensors has enabled the detection of different biomarkers for continuous, real-time human health monitoring [1][2]. Temperature, heart rate, electrical conductivity, dehydration, and glucose are some of the indicators that

• nanoparticles have demonstrated enormous advantages for sensing applications. First, alginate-based nanoparticles have a high surface area-to-volume ratio. This feature allows for increased interaction with the target analyte, leading to enhanced sensitivity and detection capabilities. Additionally, alginate

Signal generation in dynamic interferometric displacement detection

• Knarik Khachatryan,
• Simon Anter,
• Michael Reichling and
• Alexander von Schmidsfeld

Beilstein J. Nanotechnol. 2024, 15, 1070–1076, doi:10.3762/bjnano.15.87

• . Keywords: amplitude calibration; displacement detection; force microscopy; interferometer signal; NC-AFM; Introduction Optical interferometry is a reliable technique utilizing light waves to measure distance and displacement with high precision [1][2]. With the light wavelength as the length standard, a

• curve, where the slope of IM(d) is a maximum. Such an adjustment facilitates a most sensitive displacement detection. Note, that it is not possible to adjust the interferometer to d0 with a small number m because of limitations in positioning the fiber end face parallel to the cantilever surface. Upon

Effect of wavelength and liquid on formation of Ag, Au, Ag/Au nanoparticles via picosecond laser ablation and SERS-based detection of DMMP

• Sree Satya Bharati Moram,
• Chandu Byram and
• Venugopal Rao Soma

Beilstein J. Nanotechnol. 2024, 15, 1054–1069, doi:10.3762/bjnano.15.86

• implications for developing more efficient and stable SERS substrates for chemical detection applications. Keywords: dimethyl methyl phosphonate; laser material interaction; metal nanoparticles; picosecond laser ablation; SERS; thiram; Introduction Metal nanoparticles (NPs) are versatile materials widely

• capable of trace detection. Dimethyl methyl phosphonate (DMMP) is commonly used as a less toxic simulant for sarin, a G-series nerve agent. DMMP can, in general, be used in making chemical weapons. Zheng et al. [30] reviewed various methods for DMMP detection, including mass-sensitive sensors, surface

• substrates is the central aspect of the sensing field because of its simple sample collection from any rough surface [36][40]. Filter paper (FP) SERS substrates are rigorously investigated for the detection of hazardous dye molecules such as crystal violet (CV) and malachite green (MG) on fish [41

Bolometric IR photoresponse based on a 3D micro-nano integrated CNT architecture

• Yasameen Al-Mafrachi,
• Sandeep Yadav,
• Sascha Preu,
• Jörg J. Schneider and
• Oktay Yilmazoglu

Beilstein J. Nanotechnol. 2024, 15, 1030–1040, doi:10.3762/bjnano.15.84

• numerous advantages at room temperature operation. New thermally isolated micro-nano architectures equipped with integrated temperature sensors should outperform their predecessors regarding various critical aspects, such as ultra-broadband detection from ultraviolet (UV) to terahertz radiation [1

• attractive options for non-cryogenic IR microbolometer and thermal detection technology. The sensitivity of a bolometer is quantified by its responsivity, which is given by the expression [11]: where ΔV is the corresponding voltage change, ΔP represents the incident power on the active detection area, Ibias

• minimum power that can be detected by the bolometer for a 1 Hz detection bandwidth. The experimental setups for the responsivity and noise measurements included several devices, such as a DC power supply, an IR laser source, an optical chopper (Thorlabs MC2000B), a low-noise transimpedance amplifier (TIA

Atomistic insights into the morphological dynamics of gold and platinum nanoparticles: MD simulations in vacuum and aqueous media

• Evangelos Voyiatzis,
• Eugenia Valsami-Jones and
• Antreas Afantitis

Beilstein J. Nanotechnol. 2024, 15, 995–1009, doi:10.3762/bjnano.15.81

• surfaces of the large NPs. This is in agreement with previous findings for Ag NPs with a similar diameter range [49]. It should be noted that the considered variations in the NP size are rather subtle and below detection for current analytical capabilities [85]. There are slight disparities between Au and

Recent progress on field-effect transistor-based biosensors: device perspective

• Billel Smaani,
• Fares Nafa,
• Mohamed Salah Benlatrech,
• Ismahan Mahdi,
• Hamza Akroum,
• Mohamed walid Azizi,
• Khaled Harrar and
• Sayan Kanungo

Beilstein J. Nanotechnol. 2024, 15, 977–994, doi:10.3762/bjnano.15.80

• to detect a wide range of biomolecules, such as proteins, DNA, and antibodies. This article presents a comprehensive review of advancements in the architectures of FET-based biosensors aiming to enhance device performance in terms of sensitivity, detection time, and selectivity. The review

• FET-based biosensors. Finally, this article proposes intriguing avenues for further research on the topology of FET-based biosensors. Keywords: biomolecule detection; biosensors; charge modulation; dielectric modulation; field-effect transistor; Review 1 Introduction In recent years, biosensor

• water bodies. Therefore, the detection of harmful pollutants in the environment is a critical issue. Numerous works have reported on the application of biosensors for environmental monitoring, especially those based on optical or electrochemical transduction platforms [10][11][12][13]. Moreover