Synthesis and the impact of hydroxyapatite nanoparticles on the viability and activity of rhizobacteria

• Bedah Rupaedah,
• Indrika Novella,
• Atiek Rostika Noviyanti,
• Diana Rakhmawaty Eddy,
• Anna Safarrida,
• Abdul Hapid,
• Zhafira Amila Haqqa,
• Suryana Suryana,
• Irwan Kurnia and
• Fathiyah Inayatirrahmi

Beilstein J. Nanotechnol. 2025, 16, 216–228, doi:10.3762/bjnano.16.17

• application and storage [7]. Nanomaterials have gained significant attention in the development of rhizobacterial carrier materials, as their effective utilization can provide protective benefits to plants, assist in nutrient absorption, and, when in gel form, significantly improve water management efficiency

• efficiency of hydrothermally synthesized nHA as a specialized carrier material for rhizobacterial strains, including Pd and Tb rhizobacteria. The results of this research have the potential to enhance the efficacy of biofertilizers formulated with nanoparticles as carriers with the aim to enhance plant

Recent advances in photothermal nanomaterials for ophthalmic applications

• Jiayuan Zhuang,
• Linhui Jia,
• Chenghao Li,
• Rui Yang,
• Jiapeng Wang,
• Wen-an Wang,
• Heng Zhou and
• Xiangxia Luo

Beilstein J. Nanotechnol. 2025, 16, 195–215, doi:10.3762/bjnano.16.16

• , and inorganic semiconductor materials that absorb light through bandgap transitions [25]. The specific photothermal properties of these materials, encompassing aspects such as range and rate of light absorption, photothermal conversion efficiency, heat transfer capability, and photothermal stability

• efficient process with photothermal conversion nearing 100% efficiency (see below in Figure 2a) [45][46][47]. The specific absorption wavelength of these metals is closely linked to their extinction cross section and particle size and shape, which are greatly influenced by the chemical capping agents and

• photothermal agents [61]. Organic small molecule dyes are easy to remove from the eye, however, they suffer from low photothermal conversion efficiency, easy photobleaching, low water solubility, and low stability [39]. Common organic small molecule dyes include cyanine dyes (e.g., indocyanine green (ICG

A review of metal-organic frameworks and polymers in mixed matrix membranes for CO₂ capture

• Charlotte Skjold Qvist Christensen,
• Nicholas Hansen,
• Mahboubeh Motadayen,
• Nina Lock,
• Martin Lahn Henriksen and
• Jonathan Quinson

Beilstein J. Nanotechnol. 2025, 16, 155–186, doi:10.3762/bjnano.16.14

• much attention [3][4]. Considerable research has been dedicated to enhancing the efficiency of CO2 capture technologies for large-scale applications, particularly in natural gas purification and post-combustion processes [5]. Various technologies are currently under investigation for the capture of CO2

• , including regenerative solvent-based absorption [2][6], fixed-bed adsorption [7], cryogenic separation techniques [8], and membrane separation methods [9][10][11][12]. Of these, membrane technology offers advantages such as exceptional stability, high efficiency, low energy consumption, and ease of

• improve CO2 permeability and selectivity to enhance the efficiency of CO2 capture. A promising approach in this field involves hybrid polymer composite membranes known as mixed matrix membranes (MMMs) [15][16][17][18][19][20][21][22]. Among the diverse range of inorganic fillers integrated into MMMs

Clays enhanced with niobium: potential in wastewater treatment and reuse as pigment with antibacterial activity

• Silvia Jaerger,
• Patricia Appelt,
• Mario Antônio Alves da Cunha,
• Fabián Ccahuana Ayma,
• Ricardo Schneider,
• Carla Bittencourt and
• Fauze Jacó Anaissi

Beilstein J. Nanotechnol. 2025, 16, 141–154, doi:10.3762/bjnano.16.13

• photocatalysts for treating solutions containing the MB dye (400 mg·L−1) at 25 °C. The results showed adsorption and photocatalysis efficiency above 94% for both samples. The blue-colored BEOx and BEPh samples were then applied as a hybrid pigment. The power pigment and its dispersion in colorless paint were

• A-BEOxP to designate the modifications with NbOPO4 and Nb2O5, respectively. The adsorption efficiency of MB by the clays was calculated using Equation 1: where C0 (mg·L−1) is the initial concentration of the solution, and Cf (mg·L−1) is the concentration of the solution after the adsorption

• experiment. The efficiency of MB photodegradation (X%) was determined by Equation 2: where M0 and Mf are the concentrations of MB at the beginning and at the end of the photocatalytic test, respectively. Dispersion of the pigments clay/Nb and clay/Nb/MB in colorless commercial paint The samples A-BEPh, A

TiO₂ immobilized on 2D mordenite: effect of hydrolysis conditions on structural, textural, and optical characteristics of the nanocomposites

• Marina G. Shelyapina,
• Rosario Isidro Yocupicio-Gaxiola,
• Gleb A. Valkovsky and
• Vitalii Petranovskii

Beilstein J. Nanotechnol. 2025, 16, 128–140, doi:10.3762/bjnano.16.12

• similarly leads to the formation of TiO2. TiO2 is a well-known photocatalyst whose efficiency depends on a number of factors, including the crystalline phase, particle size, and degree of crystallinity. The most active phase of TiO2 is considered to be anatase. Its nanoparticles usually show higher

• efficiency than the bulk phase, but the bandgap of anatase particles smaller than 10 nm is very sensitive to their size [14]. One of the disadvantages of such free photocatalyst nanoparticles is the limitation of mass transfer between solid and liquid phases. From this perspective, the problem of

Comparison of organic and inorganic hole transport layers in double perovskite material-based solar cell

• Deepika K and
• Arjun Singh

Beilstein J. Nanotechnol. 2025, 16, 119–127, doi:10.3762/bjnano.16.11

• , that is, La2NiMnO6 (LNMO), is studied with the organic and inorganic hole transport layers (HTLs) Cu2O and PEDOT:PSS. Our study yields a significant improvement in the power conversion efficiency (PCE) of perovskite solar cells with two types of HTLs. The optimized devices achieved a maximum PCE of

• Karapinar [2] fabricated a dye-sensitized solar cell (DSSC) with selenium@activated carbon (Se@AC) composites as an alternative to the Pt counter electrode (CE) via chemical activation. The fabricated DSSC showed a power conversion efficiency (PCE) of 5.67%, an open-circuit voltage (VOC) of 0.648 V, a short

• % Mn doping and an Eu compact layer, an efficiency of 4.20% was obtained. Currently, perovskite solar cells (PSCs) are attracting the attention of research communities worldwide because of their outstanding and unique properties. PSCs possess desirable characteristics such as cost-effectiveness

Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy

• Naths Grazia Sukubo,
• Paolo Bigini and
• Annalisa Morelli

Beilstein J. Nanotechnol. 2025, 16, 97–118, doi:10.3762/bjnano.16.10

• decades of technological evolution, during which NCs have become indispensable components of drug delivery systems, known for their adaptability and efficiency [2]. The “family” of nanoparticles (NPs) includes a broad range of materials such as lipids, polymers, proteins, dextran, silica [3], and metals

• ultrastructural changes in macrophages, providing nanoscale insights into inflammation. The efficiency of gold NP (AuNP)-loaded macrophages as a targeted delivery system was tested in an ovalbumin-induced asthma mouse model. Findings showed significant macrophage–NP interactions, highlighting the potential of

Characterization of ZnO nanoparticles synthesized using probiotic Lactiplantibacillus plantarum GP258

• Prashantkumar Siddappa Chakra,
• Aishwarya Banakar,
• Shriram Narayan Puranik,
• Vishwas Kaveeshwar,
• C. R. Ravikumar and
• Devaraja Gayathri

Beilstein J. Nanotechnol. 2025, 16, 78–89, doi:10.3762/bjnano.16.8

• (CV) and electrochemical impedance spectroscopy (EIS) were carried out at room temperature using a three-electrode cell with 0.1 M KCl electrolyte. The ZnO NP electrode was measured at scan rates from 10 to 50 mV/s. The measurements revealed reversibility and electrode load efficiency along with

• frequency (ω), Y, and n. The obtained results suggest robust electron transfer and enhanced electrocatalytic efficiency in dextrose oxidation [19][20][21] (Figure 5). Antibacterial activity of ZnO NPs The biogenic ZnO NPs presented a good dispersion and exhibited antibacterial activity against both Gram

• analysis, (b) Fourier-transform infrared (FTIR) spectroscopy, (c) UV–vis spectroscopy, and (d) photocatalytic efficiency of ZnO NPs. (a, b) Transmission electron microscopy (TEM) micrographs showing the morphology and size of the nanoparticles. (c) Selected area electron diffraction (SAED) pattern of ZnO

Bioinspired nanofilament coatings for scale reduction on steel

• Siad Dahir Ali,
• Mette Heidemann Rasmussen,
• Jacopo Catalano,
• Christian Husum Frederiksen and
• Tobias Weidner

Beilstein J. Nanotechnol. 2025, 16, 25–34, doi:10.3762/bjnano.16.3

• applications of mimicking the liquid-repelling properties of their skin to address a common industrial challenge: The scaling of steel surfaces. Scaling, a pervasive issue in various industries, results from unwanted water adhesion and mineral deposition, leading to corrosion, reduced efficiency, and increased

A nanocarrier containing carboxylic and histamine groups with dual action: acetylcholine hydrolysis and antidote atropine delivery

• Elina E. Mansurova,
• Andrey A. Maslennikov,
• Anna P. Lyubina,
• Alexandra D. Voloshina,
• Irek R. Nizameev,
• Marsil K. Kadirov,
• Anzhela A. Mikhailova,
• Polina V. Mikshina,
• Albina Y. Ziganshina and
• Igor S. Antipin

Beilstein J. Nanotechnol. 2025, 16, 11–24, doi:10.3762/bjnano.16.2

• carried out in a manner similar to that of p(Hist-CA). After the reaction, dialysis was carried out using a 12000 Da dialysis bag to remove unencapsulated Fl, resulting in a solution of Fl@p(Hist-CA). The encapsulation efficiency (%EE) was found to be 55%. In the UV spectra of Fl@p(Hist-CA) (PB, pH 7.4

Orientation-dependent photonic bandgaps in gold-dust weevil scales and their titania bioreplicates

• Norma Salvadores Farran,
• Limin Wang,
• Primoz Pirih and
• Bodo D. Wilts

Beilstein J. Nanotechnol. 2025, 16, 1–10, doi:10.3762/bjnano.16.1

• volumes with differing refractive indices. The diamond TPMS structure is special as it provides optimal diffraction efficiency and can form photonic bandgaps even with lower refractive index contrasts (i.e., with refractive index contrasts above 2.1) [15][17]. This makes these structures rather

Mechanistic insights into endosomal escape by sodium oleate-modified liposomes

• Ebrahim Sadaqa,
• Satrialdi,
• Fransiska Kurniawan and
• Diky Mudhakir

Beilstein J. Nanotechnol. 2024, 15, 1667–1685, doi:10.3762/bjnano.15.131

• , and AUR-Lipo formulations. The particle sizes were 102.2 ± 3.30 nm for Unmodified-Lipo, 109.6 ± 7.65 nm for SO-Lipo, and 151.9 ± 5.88 nm for AUR-Lipo, with polydispersity indices below 0.25, indicating uniform size distribution. Endosomal escape efficiency was evaluated through confocal microscopy by

• Figure 3 illustrates the assessment of endosomal escape efficiency for Unmodified-Lipo, SO-Lipo, and AUR-Lipo after 2 and 6 h of incubation. The colocalization of the DiD-labeled liposomes (red) with LysoTracker-stained lysosomes (green) is a key indicator of whether the liposomes remain trapped within

• six-hour time point (Figure 3c,d), Unmodified-Lipo continued to exhibit notable colocalization, as evidenced by the yellow areas, albeit slightly diminished. In contrast, SO-Lipo and AUR-Lipo demonstrated further decreases in Pearson’s coefficients, confirming their superior escape efficiency over

Biomimetic nanocarriers: integrating natural functions for advanced therapeutic applications

• Hugo Felix Perini,
• Beatriz Sodré Matos,
• Carlo José Freire de Oliveira and
• Marcos Vinicius da Silva

Beilstein J. Nanotechnol. 2024, 15, 1619–1626, doi:10.3762/bjnano.15.127

• such as: loss of stability, low efficiency in crossing biological barriers, inadequate efficacy in reaching target active molecules, and poor biodistribution [13][14]. Nanocarriers are employed to transport raw materials, which can be vesicles or solid nanoparticles [15]. Despite the significant

• this context, biomimetic strategies using natural components emerge as revolutionary tools to overcome these challenges. The utilization of cellular components or parts thereof, such as macromolecules or membranes, can enhance drug delivery and therapeutic efficiency in the human body, representing a

• voltage and exposure time, can be optimized to improve efficiency. Though costly, this method is suitable for industrial applications [34][45]. Another strategy exploits electrostatic charges of nanocarriers and membrane vesicles. Opposite charges (negative for vesicles and positive for carriers) foster

Liver-targeting iron oxide nanoparticles and their complexes with plant extracts for biocompatibility

• Shushanik A. Kazaryan,
• Seda A. Oganian,
• Gayane S. Vardanyan,
• Anatolie S. Sidorenko and
• Ashkhen A. Hovhannisyan

Beilstein J. Nanotechnol. 2024, 15, 1593–1602, doi:10.3762/bjnano.15.125

• interdisciplinary approach is to integrate advances in biotechnology, nanomaterials, biomedical robotics, and genetic engineering into the broader field of nanomedicine. On a larger scale, the application of nanotechnology in medicine enhances efficiency, accelerates processes, and improves functional performance

• activity, membrane leakage, and morphological changes. Toxic NPs can adversely affect cell viability, proliferation rate, and metabolic activity; also, they can reduce the therapeutic efficiency of the treatment [55]. The toxicity of NPs on biological entities fundamentally depends on the characteristics

Facile synthesis of size-tunable L-carnosine-capped silver nanoparticles and their role in metal ion sensing and catalytic degradation of p-nitrophenol

• Akash Kumar,
• Ridhima Chadha,
• Abhishek Das,
• Nandita Maiti and
• Rayavarapu Raja Gopal

Beilstein J. Nanotechnol. 2024, 15, 1576–1592, doi:10.3762/bjnano.15.124

• intensity. The catalytic efficiency was quantified using the following equation: where C0 represents the initial concentration at t = 0 and Ct denotes the concentration at time t. Results and Discussion Synthesis of ʟ-carnosine-capped tunable silver nanoparticles ʟ-car-AgNPs were synthesized using a wet

• -AgNP1 led to the degradation of 0.25 mM P-NP within 90 s of the reaction, achieving a degradation efficiency of 95.5% (Figure 9a). In comparison, ʟ-car-AgNP2, ʟ-car-AgNP3, ʟ-car-AgNP4, and ʟ-car-AgNP5 achieved complete P-NP degradation within 100, 160, 140, and 220 s, respectively, with catalytic

• -AgNP4, ʟ-car-AgNP3, and ʟ-car-AgNP2 are nearly the same, but the lower rate constant in case of AgNP5 might be due to the formation of larger aggregates, which was confirmed by optical spectroscopy and TEM analysis. The high efficiency of AgNP2 might be due to its quasi-spherical shape. The catalytic

Ultrablack color in velvet ant cuticle

• Vinicius Marques Lopez,
• Wencke Krings,
• Juliana Reis Machado,
• Stanislav Gorb and
• Rhainer Guillermo-Ferreira

Beilstein J. Nanotechnol. 2024, 15, 1554–1565, doi:10.3762/bjnano.15.122

• distribution and organization of such microstructures influence the absorption efficiency and potential adaptive significance of ultrablack coloration in different ecological contexts. The role of ultrablack colors in nature is still a topic of debate, with limited evidence regarding the selective pressures

• pigment absorption that results in these remarkably absorptive surface. Especially, this kind of wasp-inspired technology may have its application in increasing efficiency of solar panels [20]. Further research is needed to uncover the mechanisms and functional roles of ultrablack coloration in velvet

The round-robin approach applied to nanoinformatics: consensus prediction of nanomaterials zeta potential

• Dimitra-Danai Varsou,
• Arkaprava Banerjee,
• Joyita Roy,
• Kunal Roy,
• Giannis Savvas,
• Haralambos Sarimveis,
• Ewelina Wyrzykowska,
• Mateusz Balicki,
• Tomasz Puzyn,
• Georgia Melagraki,
• Iseult Lynch and
• Antreas Afantitis

Beilstein J. Nanotechnol. 2024, 15, 1536–1553, doi:10.3762/bjnano.15.121

• possessing modest individual predictive prowess. However, when integrated into an ensemble, they collectively augment the predictive efficiency of the model. A notable distinction between the random forest algorithm and AdaBoost lies in their operational frameworks. In the random forest, individual

• -across and QSPR, has been recently introduced and applied to the prediction of NM cytotoxicity [44], power conversion efficiency of organic dyes in dye-sensitized solar cells [45][46], detonation heat for nitrogen containing compounds [47], and to the prediction of surface area of perovskite materials

• materials being studied, (ii) a random forest model, and (iii) an AdaBoost regression model, both of which stand out for their speed and computational efficiency. Last, two quantitative read-across structure-property relationship (q-RASPR) models were included that combine the advantages of read-across and

Integrating high-performance computing, machine learning, data management workflows, and infrastructures for multiscale simulations and nanomaterials technologies

• Fabio Le Piane,
• Mario Vozza,
• Matteo Baldoni and
• Francesco Mercuri

Beilstein J. Nanotechnol. 2024, 15, 1498–1521, doi:10.3762/bjnano.15.119

• efficiency of materials research. The integration of digital technologies into materials science has, thus, opened up exciting new possibilities for materials design, discovery, and innovation [14]. New, fully digitalized research directions for materials development are therefore emerging at the convergence

• computational challenges with greater speed and efficiency. The availability of powerful processors, increased memory capacity, and enhanced parallel computing architectures has significantly accelerated materials simulations and modelling [17]. In parallel, software technologies have undergone remarkable

• in materials development. Beside the implementation of automation and robotics in the development, synthesis, and characterization of materials, automation in modelling has emerged as a powerful approach to streamline and enhance the efficiency of computational studies. By leveraging digital

Polymer lipid hybrid nanoparticles for phytochemical delivery: challenges, progress, and future prospects

• Iqra Rahat,
• Pooja Yadav,
• Aditi Singhal,
• Mohammad Fareed,
• Jaganathan Raja Purushothaman,
• Mohammed Aslam,
• Raju Balaji,
• Sonali Patil-Shinde and
• Md. Rizwanullah

Beilstein J. Nanotechnol. 2024, 15, 1473–1497, doi:10.3762/bjnano.15.118

• . We discuss the obstacles in the conventional delivery of phytochemicals, the fundamental architecture of PLHNPs, and the types of PLHNPs, highlighting their ability to improve encapsulation efficiency, stability, and controlled release of the encapsulated phytochemicals. In addition, the surface

• polyethylene glycol (PEG), poly(lactic-co-glycolic acid) (PLGA), polycaprolactone (PCL), and chitosan (CHS), provides structural integrity, controlled release properties, and protection against premature degradation [14][15]. This hybrid structure improves the encapsulation efficiency of phytochemicals/drugs

• include their small particle size, high encapsulation efficiency, enhanced stability, and improved dissolution in harsh gastrointestinal (GI) fluids. Following oral administration, PLHNPs demonstrate superior intestinal absorption and bioavailability, attributed to their enhanced stability and dissolution

Ion-induced surface reactions and deposition from Pt(CO)₂Cl₂ and Pt(CO)₂Br₂

• Mohammed K. Abdel-Rahman,
• Patrick M. Eckhert,
• Atul Chaudhary,
• Johnathon M. Johnson,
• Jo-Chi Yu,
• Lisa McElwee-White and
• D. Howard Fairbrother

Beilstein J. Nanotechnol. 2024, 15, 1427–1439, doi:10.3762/bjnano.15.115

• atoms before the residual metal atoms are ultimately removed by physical sputtering, is analogous to the ion-induced reactions with adsorbed Ru(CO)4I2 [23]. In the present study, the relative efficiency of Pt atom sputtering is expected to be greatest for the heavier Ar+ ions [37][41]. Indeed, other

Lithium niobate on insulator: an emerging nanophotonic crystal for optimized light control

• Midhun Murali,
• Amit Banerjee and
• Tanmoy Basu

Beilstein J. Nanotechnol. 2024, 15, 1415–1426, doi:10.3762/bjnano.15.114

• to capture a wider range of sunlight compared to traditional materials, potentially leading to higher solar energy conversion efficiency [43]. Bae et al. focussed on lead sulfide (PbS) CQDs solar cells where they addressed the major challenge of charge carrier recombination which limits the

• resonant wavelength of the DBR can be selectively enhanced without increasing the CQD film thickness, thereby overcoming the inherent tradeoff in these devices. The combination of FP resonance and DBR increases the power conversion efficiency (PCE) of PbS CQD solar cells by 54% and enables a very thin PbS

• layer to absorb four times more near-infrared light [43]. Flip-chip micro light-emitting diodes (micro-LEDs) are a revolutionary technology with the potential to create next-generation HDR displays due to their tiny size, exceptional brightness, wide color gamut, and energy efficiency [44][45][46

Nanotechnological approaches for efficient N2B delivery: from small-molecule drugs to biopharmaceuticals

• Selin Akpinar Adscheid,
• Akif E. Türeli,
• Nazende Günday-Türeli and
• Marc Schneider

Beilstein J. Nanotechnol. 2024, 15, 1400–1414, doi:10.3762/bjnano.15.113

• . While the systemic route of administration with the combination of drug delivery systems (DDSs) to cross the BBB has been promising, the efficiency is often not yet satisfactory [17]. Another noninvasive technique, nose-to-brain delivery or nasal-to-brain delivery (N2B delivery), in contrast, bypasses

• opportunity to modify the release profile of the drugs, enhance targeting efficiency, and improve nasal permeation during intranasal administration [21][22][23][24]. In general, the encapsulation of active pharmaceutical ingredients (APIs) into mucoadhesive DDSs can mitigate rapid mucociliary clearance [25

• showed higher encapsulation efficiency for the positively charged ghrelin at pH 7.4, indicating that the choice of the anionic/cationic liposomes should be based on the desired application as well as the encapsulated substance. Moreover, a chitosan chloride coating increased mucin adsorption by

Out-of-plane polarization induces a picosecond photoresponse in rhombohedral stacked bilayer WSe₂

• Guixian Liu,
• Yufan Wang,
• Zhoujuan Xu,
• Zhouxiaosong Zeng,
• Lanyu Huang,
• Cuihuan Ge and
• Xiao Wang

Beilstein J. Nanotechnol. 2024, 15, 1362–1368, doi:10.3762/bjnano.15.109

• .15.109 Abstract Constructing van der Waals materials with spontaneous out-of-plane polarization through interlayer engineering expands the family of two-dimensional ferroelectrics and provides an excellent platform for enhancing the photoelectric conversion efficiency. Here, we reveal the effect of

• lead to a high-efficiency photoelectric conversion that has the potential to surpasses the Shockley–Queisser limit [24][31][32][33][34]. In this regard, constructing 2D vdW semiconductors with OOP polarization and moderate bandgap holds great promise for high-performance self-powered BPVE devices. More

Hymenoptera and biomimetic surfaces: insights and innovations

• Vinicius Marques Lopez,
• Carlo Polidori and
• Rhainer Guillermo Ferreira

Beilstein J. Nanotechnol. 2024, 15, 1333–1352, doi:10.3762/bjnano.15.107

• materials and devices that replicate the efficiency and functionality of insect body structures, driving progress in medical technology, robotics, environmental monitoring, and beyond. Keywords: arthropods; bio-inspired surfaces; bioengineering; cuticle; nanoscale structures; Introduction The body

• , scientists and engineers can develop innovative materials and devices that mirror the efficiency and functionality of Hymenopteran anatomy. Here we describe the structural adaptations on the surfaces of the body of Hymenoptera (Figure 2) with potential biomimetic applications. By analyzing their unique

• of some species reduce friction and wear, inspiring the development of low-friction materials and coatings. By mimicking these natural textures, it is possible to create synthetic materials that exhibit similar friction-reducing properties, leading to significant advancements in mechanical efficiency

Nanoarchitectonics with cetrimonium bromide on metal nanoparticles for linker-free detection of toxic metal ions and catalytic degradation of 4-nitrophenol

• Akash Kumar and
• Raja Gopal Rayavarapu

Beilstein J. Nanotechnol. 2024, 15, 1312–1332, doi:10.3762/bjnano.15.106

• , metal composition, centrifugation, and NaOH amount, were investigated for their impact on the performance of CTAB-capped nanoparticles in heavy metal detection and 4-NP degradation. CTAB-Au nanospheres demonstrated limited heavy metal ion detection capability but exhibited remarkable efficiency in