The role of adatoms in chloride-activated colloidal silver nanoparticles for surface-enhanced Raman scattering enhancement

• Nicolae Leopold,
• Andrei Stefancu,
• Krisztian Herman,
• István Sz. Tódor,
• Stefania D. Iancu,
• Vlad Moisoiu and
• Loredana F. Leopold

Beilstein J. Nanotechnol. 2018, 9, 2236–2247, doi:10.3762/bjnano.9.208

• Medicine, Manastur 3-5, 400372 Cluj-Napoca, Romania 10.3762/bjnano.9.208 Abstract Chloride-capped silver nanoparticles (Cl-AgNPs) allow for high-intensity surface-enhanced Raman scattering (SERS) spectra of cationic molecules to be obtained (even at nanomolar concentration) and may also play a key role in

Fabrication of photothermally active poly(vinyl alcohol) films with gold nanostars for antibacterial applications

• Mykola Borzenkov,
• Maria Moros,
• Claudia Tortiglione,
• Serena Bertoldi,
• Nicola Contessi,
• Silvia Faré,
• Angelo Taglietti,
• Agnese D’Agostino,
• Piersandro Pallavicini,
• Maddalena Collini and
• Giuseppe Chirico

Beilstein J. Nanotechnol. 2018, 9, 2040–2048, doi:10.3762/bjnano.9.193

• Mykola Borzenkov Maria Moros Claudia Tortiglione Serena Bertoldi Nicola Contessi Silvia Fare Angelo Taglietti Agnese D'Agostino Piersandro Pallavicini Maddalena Collini Giuseppe Chirico Department of Medicine and Surgery, Nanomedicine Center, University of Milano-Bicocca, Piazza dell’Ateneo Nuovo

Biomimetic and biodegradable cellulose acetate scaffolds loaded with dexamethasone for bone implants

• Aikaterini-Rafailia Tsiapla,
• Varvara Karagkiozaki,
• Veroniki Bakola,
• Foteini Pappa,
• Panagiota Gkertsiou,
• Eleni Pavlidou and
• Stergios Logothetidis

Beilstein J. Nanotechnol. 2018, 9, 1986–1994, doi:10.3762/bjnano.9.189

• inflammations along with a simultaneous controlled release of the drug. Keywords: drug delivery; electrospinning; nanocoatings; orthopedics; tissue engineering; Introduction The application of nanotechnology in medicine, known as nanomedicine, aims to overcome problems associated with diseases at the

Preparation of micro/nanopatterned gelatins crosslinked with genipin for biocompatible dental implants

• Reika Makita,
• Tsukasa Akasaka,
• Seiichi Tamagawa,
• Yasuhiro Yoshida,
• Saori Miyata,
• Hirofumi Miyaji and
• Tsutomu Sugaya

Beilstein J. Nanotechnol. 2018, 9, 1735–1754, doi:10.3762/bjnano.9.165

• Reika Makita Tsukasa Akasaka Seiichi Tamagawa Yasuhiro Yoshida Saori Miyata Hirofumi Miyaji Tsutomu Sugaya Department of Periodontology and Endodontology, Graduate School of Dental Medicine, Hokkaido University, Sapporo 060-8586, Japan Department of Biomaterials and Bioengineering, Faculty of

• Dental Medicine, Hokkaido University, Sapporo 060-8586, Japan School of Dental Medicine, Hokkaido University, Sapporo 060-8586, Japan Department of Periodontology and Endodontology, Faculty of Dental Medicine, Hokkaido University, Sapporo 060-8586, Japan 10.3762/bjnano.9.165 Abstract Background

Atomic-level characterization and cilostazol affinity of poly(lactic acid) nanoparticles conjugated with differentially charged hydrophilic molecules

• María Francisca Matus,
• Martín Ludueña,
• Cristian Vilos,
• Iván Palomo and
• Marcelo M. Mariscal

Beilstein J. Nanotechnol. 2018, 9, 1328–1338, doi:10.3762/bjnano.9.126

• , Talca, Chile INFIQC, CONICET, Departamento de Química Teórica y Computacional, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, XUA5000 Córdoba, Argentina Laboratory of Nanomedicine and Targeted Delivery, Center for Integrative Medicine and Innovative Science (CIMIS), Faculty of Medicine

• promising field for numerous diseases and represents the forefront of modern medicine. In the present work, full atomistic computer simulations were applied to study poly(lactic acid) (PLA) nanoparticles conjugated with polyethylene glycol (PEG). The formation of this complex system was simulated using the

Surface characterization of nanoparticles using near-field light scattering

• Eunsoo Yoo,
• Yizhong Liu,
• Chukwuazam A. Nwasike,
• Sebastian R. Freeman,
• Brian C. DiPaolo,
• Bernardo Cordovez and
• Amber L. Doiron

Beilstein J. Nanotechnol. 2018, 9, 1228–1238, doi:10.3762/bjnano.9.114

• reaction kinetics at the particle surface. Keywords: nanoparticle surface properties; nanoparticles; nanophotonic force microscopy; near-field light scattering; superparamagnetic iron oxide; Introduction Nanotechnology is an increasingly integral part of modern medicine, predominantly in the fields of

Bioinspired self-healing materials: lessons from nature

• Joseph C. Cremaldi and
• Bharat Bhushan

Beilstein J. Nanotechnol. 2018, 9, 907–935, doi:10.3762/bjnano.9.85

• ] states that regenerative medicine “…seeks to repair or regenerate damaged tissue and organs…without leaving scar tissue behind, thereby restoring both structure and function of tissues/organs.” The overall goal of life is to survive, and healing is one of the tools an organism uses to achieve this goal

Comparative study of antibacterial properties of polystyrene films with TiO_x and Cu nanoparticles fabricated using cluster beam technique

• Vladimir N. Popok,
• Cesarino M. Jeppesen,
• Peter Fojan,
• Anna Kuzminova,
• Jan Hanuš and
• Ondřej Kylián

Beilstein J. Nanotechnol. 2018, 9, 861–869, doi:10.3762/bjnano.9.80

• 10.3762/bjnano.9.80 Abstract Background: Antibacterial materials are of high importance for medicine, and for the production and conservation of food. Among these materials, polymer films with metal nanoparticles (NPs) are of considerable interest for many practical applications. Results: The paper

• of consumables for medicine (for example, catheters for drug delivery) [7][8]. There are different ways for the formation of polymers with metal NPs. Particles can be synthesized in situ using the organic matrix as the reaction medium or ex situ by chemical or physical means and then incorporated

Heavy-metal detectors based on modified ferrite nanoparticles

• Urszula Klekotka,
• Ewelina Wińska,
• Elżbieta Zambrzycka-Szelewa,
• Dariusz Satuła and
• Beata Kalska-Szostko

Beilstein J. Nanotechnol. 2018, 9, 762–770, doi:10.3762/bjnano.9.69

• nanoparticles can be widely used in medicine for drug delivery, implants manufacture, as components of contrast agents in magnetic resonance imaging (MRI) as well as active centers in hyperthermia treatment [1]. The use of magnetic nanoparticles in drug delivery allows for a significant reduction of the amount

Nanoparticle delivery to metastatic breast cancer cells by nanoengineered mesenchymal stem cells

• Liga Saulite,
• Karlis Pleiko,
• Ineta Popena,
• Dominyka Dapkute,
• Ricardas Rotomskis and
• Una Riekstina

Beilstein J. Nanotechnol. 2018, 9, 321–332, doi:10.3762/bjnano.9.32

• Liga Saulite Karlis Pleiko Ineta Popena Dominyka Dapkute Ricardas Rotomskis Una Riekstina Faculty of Medicine, University of Latvia, Raina Blvd. 19, LV-1586 Riga, Latvia Biomedical Physics Laboratory, National Cancer Institute, P. Baublio Street 3b, LT-08406 Vilnius, Lithuania Life Science Center

• nanoparticle delivery vehicles to specifically target metastatic breast cancer cells. Experimental Cell culture Primary human skin mesenchymal stem cells (MSCs) from frozen primary cell stock were used in accordance with authorised approval from the Institute of Experimental and Clinical Medicine Ethics

Dynamic behavior of a nematic liquid crystal with added carbon nanotubes in an electric field

• Emil Petrescu and
• Cristina Cirtoaje

Beilstein J. Nanotechnol. 2018, 9, 233–241, doi:10.3762/bjnano.9.25

• : Fréedericksz transition, nanotubes; Introduction The increased interest for nanomaterials in different domains such as chemistry, medicine or engineering, makes their characterization quite necessary. This might be the reason why there are so many research papers presenting new materials and new experiments

Liquid-crystalline nanoarchitectures for tissue engineering

• Baeckkyoung Sung and
• Min-Ho Kim

Beilstein J. Nanotechnol. 2018, 9, 205–215, doi:10.3762/bjnano.9.22

• challenges for applying LC nanoarchitectures in tissue engineering fields is discussed. Keywords: biocolloid; biopolymer; cell-matrix interaction; mesophase; regenerative medicine; Review Introduction Liquid crystals (LCs) are ubiquitous in our life [1]. On one hand, LC materials play a central role in

• not yet been sufficiently recognized among scientists in the field of tissue engineering and regenerative medicine, or even among experts in fields of LC technology. The objective of this review article is to deal with this issue with a multidisciplinary point of view. First, the ultrastructures and

• discussed, in the context of their applications to cell templates and scaffolds for regenerative medicine. In particular, it is discussed how varying nanoarchitectures in different LC orders have been realized in several tissue engineering topics. Lastly, a perspective on the opportunities and challenges

Co-reductive fabrication of carbon nanodots with high quantum yield for bioimaging of bacteria

• Jiajun Wang,
• Xia Liu,
• Gesmi Milcovich,
• Tzu-Yu Chen,
• Edel Durack,
• Sarah Mallen,
• Yongming Ruan,
• Xuexiang Weng and
• Sarah P. Hudson

Beilstein J. Nanotechnol. 2018, 9, 137–145, doi:10.3762/bjnano.9.16

• medicine. Within this class of materials, carbon nanodots (C-dots) are deemed a major breakthrough for the development of fluorescent nanomaterials. They are a promising alternative to fluorescent inorganic semiconductor nanocrystals and organic dyes due to their chemical stability, good dispersibility in

Hyperthermic intracavitary nanoaerosol therapy (HINAT) as an improved approach for pressurised intraperitoneal aerosol chemotherapy (PIPAC): Technical description, experimental validation and first proof of concept

• Daniel Göhler,
• Stephan Große,
• Alexander Bellendorf,
• Thomas Albert Falkenstein,
• Mehdi Ouaissi,
• Jürgen Zieren,
• Michael Stintz and
• Urs Giger-Pabst

Beilstein J. Nanotechnol. 2017, 8, 2729–2740, doi:10.3762/bjnano.8.272

• -01062 Dresden, Germany Technologieorientierte Partikel-, Analysen- und Sensortechnik, Topas GmbH, Oskar-Röder Straße 12, D-01237 Dresden, Germany Clinic for Nuclear Medicine, University Hospital Essen, Hufelandstraße 55, D-45147 Essen, Germany Basic Research Laboratory Department of Surgery, St. Mary’s

Dry adhesives from carbon nanofibers grown in an open ethanol flame

• Christian Lutz,
• Julia Syurik,
• C. N. Shyam Kumar,
• Christian Kübel,
• Michael Bruns and
• Hendrik Hölscher

Beilstein J. Nanotechnol. 2017, 8, 2719–2728, doi:10.3762/bjnano.8.271

• ], manufacturing processes to transfer objects [23] and plasters in medicine [24]. Polymer-based dry adhesives [25][26][27] benefit from easy fabrication routes and low production cost. However, there are several polymer-related problems, such as thermal instability at elevated temperatures and creep [28

Synthesis of [{AgO₂CCH₂OMe(PPh₃)}_n] and theoretical study of its use in focused electron beam induced deposition

• Jelena Tamuliene,
• Julian Noll,
• Peter Frenzel,
• Tobias Rüffer,
• Alexander Jakob,
• Bernhard Walfort and
• Heinrich Lang

Beilstein J. Nanotechnol. 2017, 8, 2615–2624, doi:10.3762/bjnano.8.262

• metals [5]. In this context, the deposition of, for example, silver is challenging, since there is a lack of volatile silver precursors for FEBID processes [5]. Silver (nano)structures are of importance, for example, in circuits, batteries, LED or RFID chips, medicine and photovoltaics [1]. Recently, it

Involvement of two uptake mechanisms of gold and iron oxide nanoparticles in a co-exposure scenario using mouse macrophages

• Dimitri Vanhecke,
• Dagmar A. Kuhn,
• Dorleta Jimenez de Aberasturi,
• Sandor Balog,
• Ana Milosevic,
• Dominic Urban,
• Diana Peckys,
• Niels de Jonge,
• Wolfgang J. Parak,
• Alke Petri-Fink and
• Barbara Rothen-Rutishauser

Beilstein J. Nanotechnol. 2017, 8, 2396–2409, doi:10.3762/bjnano.8.239

• rise of nanotechnology-containing products [1]. Numerous contemporary developments in consumer products (e.g., food additives, cosmetics and sporting equipment), environmental remediation, medicine and information technology heavily rely on innovative nanomaterial-driven industrial technology [2]. A

Molecular dynamics simulations of nanoindentation and scratch in Cu grain boundaries

• Shih-Wei Liang,
• Ren-Zheng Qiu and
• Te-Hua Fang

Beilstein J. Nanotechnol. 2017, 8, 2283–2295, doi:10.3762/bjnano.8.228

• in nanotechnology have allowed the related research techniques to be applied to diverse fields including physics, energy, medicine, and industrial engineering, among others [1][2]. In this sense, nanoindentation [3][4][5][6][7][8][9][10][11][12] and nanoscratch [13][14][15][16][17][18][19][20][21

Optical techniques for cervical neoplasia detection

• Tatiana Novikova

Beilstein J. Nanotechnol. 2017, 8, 1844–1862, doi:10.3762/bjnano.8.186

• medicine [69][70][71][72]. Due to its ability to provide real-time structural information on superficial layers of tissue this technique was also applied for the detection of precancerous lesions of the uterine cervix [73][74][75][76]. A fiber-optic reflectance confocal microscope was used by Carlson et al

Evaluation of preparation methods for suspended nano-objects on substrates for dimensional measurements by atomic force microscopy

• Petra Fiala,
• Daniel Göhler,
• Benno Wessely,
• Michael Stintz,
• Giovanni Mattia Lazzerini and
• Andrew Yacoot

Beilstein J. Nanotechnol. 2017, 8, 1774–1785, doi:10.3762/bjnano.8.179

• , nanotechnology is an increasingly important part of particle technology, owing to the diversity of applications of nanoparticles (NP) in product improvement and development especially in food industry [1], pharmacy, cosmetics and medicine [2]. According to ISO/TS 80004-1:2010 [3], nanomaterials can be classified

Uptake and intracellular accumulation of diamond nanoparticles – a metabolic and cytotoxic study

• Antonín Brož,
• Lucie Bačáková,
• Pavla Štenclová,
• Alexander Kromka and
• Štěpán Potocký

Beilstein J. Nanotechnol. 2017, 8, 1649–1657, doi:10.3762/bjnano.8.165

• are tailorable on demand [2]. This work investigates the use of diamond nanomaterials, or nanodiamonds (NDs), especially in life sciences, tissue engineering and regenerative medicine [3][4][5][6]. Diamond is biocompatible [7][8], and for advanced biomedical applications, it is particularly promising

Development of an advanced diagnostic concept for intestinal inflammation: molecular visualisation of nitric oxide in macrophages by functional poly(lactic-co-glycolic acid) microspheres

• Kathleen Lange,
• Christian Lautenschläger,
• Maria Wallert,
• Stefan Lorkowski,
• Andreas Stallmach and
• Alexander Schiller

Beilstein J. Nanotechnol. 2017, 8, 1637–1641, doi:10.3762/bjnano.8.163

• Kathleen Lange Christian Lautenschlager Maria Wallert Stefan Lorkowski Andreas Stallmach Alexander Schiller Jena University Hospital, Department of Internal Medicine IV (Gastroenterology, Hepatology, Infectiology), Am Klinikum 1, 07743 Jena, Germany Atherothrombosis and Vascular Laboratory, Baker

Luminescent supramolecular hydrogels from a tripeptide and nitrogen-doped carbon nanodots

• Maria C. Cringoli,
• Slavko Kralj,
• Marina Kurbasic,
• Massimo Urban and
• Silvia Marchesan

Beilstein J. Nanotechnol. 2017, 8, 1553–1562, doi:10.3762/bjnano.8.157

• materials. Peptide self-assembled hydrogels are inherently biocompatible and biodegradable and thus are promising biomaterials for cell culture, regenerative medicine, tissue engineering, and drug delivery applications [22]. The identification of self-assembling peptides that are as short as possible is

Nanostructures for sensors, electronics, energy and environment III

• Nunzio Motta

Beilstein J. Nanotechnol. 2017, 8, 1530–1531, doi:10.3762/bjnano.8.154

• medicine and pharmacology, where nanoparticles are the carriers of drugs targeted on the disease (i.e., only the sick cells). In the middle there is a plethora of different materials and approaches, including nanotubes and two-dimensional materials such as graphene, and graphene-like materials (e.g

A biofunctionalizable ink platform composed of catechol-modified chitosan and reduced graphene oxide/platinum nanocomposite

• Peter Sobolewski,
• Agata Goszczyńska,
• Małgorzata Aleksandrzak,
• Karolina Urbaś,
• Joanna Derkowska,
• Agnieszka Bartoszewska,
• Jacek Podolski,
• Ewa Mijowska and
• Mirosława El Fray

Beilstein J. Nanotechnol. 2017, 8, 1508–1514, doi:10.3762/bjnano.8.151

• ; catechol; chitosan; graphene; piezoelectric printing; Introduction Biosensors are a key enabling technology for the paradigm shift towards decentralized, personalized and targeted medicine. They offer the potential to utilize the wealth of information provided by modern molecular biology (genomics and