Nano-engineered skin mesenchymal stem cells: potential vehicles for tumour-targeted quantum-dot delivery

• Liga Saulite,
• Dominyka Dapkute,
• Karlis Pleiko,
• Ineta Popena,
• Simona Steponkiene,
• Ricardas Rotomskis and
• Una Riekstina

Beilstein J. Nanotechnol. 2017, 8, 1218–1230, doi:10.3762/bjnano.8.123

• Liga Saulite Dominyka Dapkute Karlis Pleiko Ineta Popena Simona Steponkiene Ricardas Rotomskis Una Riekstina Faculty of Medicine, University of Latvia, Raina blvd. 19, LV-1586, Riga, Latvia Biomedical Physics Laboratory, National Cancer Institute, P. Baublio Street 3b, LT-08406 Vilnius, Lithuania

• culture Human skin samples were obtained from post-surgery materials with authorized approval from Research Ethics Committee, Institute of Experimental and Clinical Medicine, University of Latvia (issued 04.06.2014). Dermal MSC cultures were obtained as described elsewhere [59]. In brief, skin specimens

Surface-enhanced Raman spectroscopy of cell lysates mixed with silver nanoparticles for tumor classification

• Mohamed Hassoun,
• Iwan W.Schie,
• Tatiana Tolstik,
• Sarmiza E. Stanca,
• Christoph Krafft and
• Juergen Popp

Beilstein J. Nanotechnol. 2017, 8, 1183–1190, doi:10.3762/bjnano.8.120

• Jena, Germany Department of Internal Medicine IV, Division of Gastroenterology, Hepatology and Infectious Diseases, Jena University Hospital, Erlanger Allee 101, 07745 Jena, Germany 10.3762/bjnano.8.120 Abstract The throughput of spontaneous Raman spectroscopy for cell identification applications is

Optical response of heterogeneous polymer layers containing silver nanostructures

• Miriam Carlberg,
• Florent Pourcin,
• Olivier Margeat,
• Judikaël Le Rouzo,
• Gérard Berginc,
• Rose-Marie Sauvage,
• Jörg Ackermann and
• Ludovic Escoubas

Beilstein J. Nanotechnol. 2017, 8, 1065–1072, doi:10.3762/bjnano.8.108

• ; Introduction Noble metal nanoparticles (NPs) are of considerable interest in various domains, ranging from chemistry to medicine and light filtering [1][2][3][4][5][6]. Silver NPs are especially challenging because of the possibility to control the phenomenon of light–matter interaction in the visible

Tuning the spin coherence time of Cu(II)−(bis)oxamato and Cu(II)−(bis)oxamidato complexes by advanced ESR pulse protocols

• Ruslan Zaripov,
• Evgeniya Vavilova,
• Iskander Khairuzhdinov,
• Kev Salikhov,
• Violeta Voronkova,
• Mohammad A. Abdulmalic,
• Francois E. Meva,
• Saddam Weheabby,
• Tobias Rüffer,
• Bernd Büchner and
• Vladislav Kataev

Beilstein J. Nanotechnol. 2017, 8, 943–955, doi:10.3762/bjnano.8.96

• Technische Universität Chemnitz, Fakultät für Naturwissenschaften, Institut für Chemie, Straße der Nationen 62, D-09111 Chemnitz, Germany Department of Pharmaceutical Sciences, Faculty of Medicine and Pharmaceutical Sciences, University of Douala, BP 2701, Cameroon Leibniz Institute for Solid State and

Probing the magnetic superexchange couplings between terminal Cu^II ions in heterotrinuclear bis(oxamidato) type complexes

• Mohammad A. Abdulmalic,
• Saddam Weheabby,
• Francois E. Meva,
• Azar Aliabadi,
• Vladislav Kataev,
• Bernd Büchner,
• Frederik Schleife,
• Berthold Kersting and
• Tobias Rüffer

Beilstein J. Nanotechnol. 2017, 8, 789–800, doi:10.3762/bjnano.8.82

• , Germany Department of Pharmaceutical Sciences, Faculty of Medicine and Pharmaceutical Sciences, University of Douala, BP 2701, Cameroon Leibniz Institute for Solid State and Materials Research IFW Dresden, D-01171 Dresden, Germany Institut für Nanospektroskopie (EM-ISPEK), Helmholtz-Zentrum Berlin für

Selective detection of Mg²⁺ ions via enhanced fluorescence emission using Au–DNA nanocomposites

• Tanushree Basu,
• Khyati Rana,
• Niranjan Das and
• Bonamali Pal

Beilstein J. Nanotechnol. 2017, 8, 762–771, doi:10.3762/bjnano.8.79

• the known concentration (50–120 ppm) of Mg2+ ions in synthetic tap water and a real life sample of Gelusil (300–360 ppm Mg2+), a widely used antacid medicine. Therefore, this method could be a sensitive tool for the estimation of water hardness after careful preparation of a suitably designed Au–DNA

• agents [5]. Currently, most of the research activities on Au–DNA nanocomposites (NCs) are in the field of therapeutics, medicine, and gene therapy. For example, in 2014, Li and co-workers reported the detection of the heavy metals Hg2+ and Cu2+ using a DNA–Ag nanocomposite system [6]. They demonstrated

• medicine. Similarly, using the Au–DNA NC detection system, we determined the amount of Mg2+ present in the tap water. It was obtained as 52 ppm by converting the intensity into concentration using the values of the calibration curve. The concentration values as obtained from the calibration curve were

Silicon microgrooves for contact guidance of human aortic endothelial cells

• Sara Fernández-Castillejo,
• Pilar Formentín,
• Úrsula Catalán,
• Josep Pallarès,
• Lluís F. Marsal and
• Rosa Solà

Beilstein J. Nanotechnol. 2017, 8, 675–681, doi:10.3762/bjnano.8.72

• Sara Fernandez-Castillejo Pilar Formentin Ursula Catalan Josep Pallares Lluis F. Marsal Rosa Sola Unit of Lipids and Atherosclerosis Research, Department of Medicine and Surgery, Universitat Rovira I Virgili, Sant Llorenç 21, 43201 Reus, Tarragona, Spain Nano-electronic and Photonic Systems

Dispersion of single-wall carbon nanotubes with supramolecular Congo red – properties of the complexes and mechanism of the interaction

• Anna Jagusiak,
• Barbara Piekarska,
• Tomasz Pańczyk,
• Małgorzata Jemioła-Rzemińska,
• Elżbieta Bielańska,
• Barbara Stopa,
• Grzegorz Zemanek,
• Janina Rybarska,
• Irena Roterman and
• Leszek Konieczny

Beilstein J. Nanotechnol. 2017, 8, 636–648, doi:10.3762/bjnano.8.68

• Anna Jagusiak Barbara Piekarska Tomasz Panczyk Malgorzata Jemiola-Rzeminska Elzbieta Bielanska Barbara Stopa Grzegorz Zemanek Janina Rybarska Irena Roterman Leszek Konieczny Chair of Medical Biochemistry, Faculty of Medicine, Jagiellonian University Medical College, Kopernika 7, Kraków 31-034

• ; Introduction Carbon nanotubes (CNTs) present enormous application potential in many areas of chemistry, technology and medicine and are currently one of the most intensely studied nanomaterials. Biomedical use of CNTs includes biosensors [1], bioimaging [2][3], drug delivery [4][5][6][7][8][9] and tissue

• medicine" (co-financed by the European Social Fund within the Human Capital Operational Programme) and Ministry of Science and Higher Education (grant no. K/DSC/001370)

α-((4-Cyanobenzoyl)oxy)-ω-methyl poly(ethylene glycol): a new stabilizer for silver nanoparticles

• Jana Lutze,
• Miguel A. Bañares,
• Marcos Pita,
• Andrea Haase,
• Andreas Luch and
• Andreas Taubert

Beilstein J. Nanotechnol. 2017, 8, 627–635, doi:10.3762/bjnano.8.67

• in, e.g., electronics or medicine [1][2][3]. Metallic nanoparticles intended for use in medicine or diagnostics are generally modified with an organic coating designed to prevent or at least to reduce aggregation in aqueous media [4][5][6][7][8][9][10][11][12][13]. A good stabilizing agent is thus

• the nanoparticle dispersion. The new polymeric stabilizer CBAmPEG may thus be interesting for application in biology, medicine, or diagnostics. A) 1H NMR spectrum, B) magnified view of the NMR signals, C) overview FTIR spectrum, and D) detailed view of the spectral region with the most intense signals

Physics, chemistry and biology of functional nanostructures III

• Anatolie S. Sidorenko

Beilstein J. Nanotechnol. 2017, 8, 590–591, doi:10.3762/bjnano.8.63

• century, influencing many areas such as electronics, biology, medicine, aerospace, agriculture, and the engineering of novel materials. Recently a new aspect of nanoscience and nanotechnology appeared and has been rising rapidly ever since: functional nanostructures, intelligent nanostructures for

Innovations from the “ivory tower”: Wilhelm Barthlott and the paradigm shift in surface science

• Christoph Neinhuis

Beilstein J. Nanotechnol. 2017, 8, 394–402, doi:10.3762/bjnano.8.41

• their conception. In this regard, Leonardo da Vinci is one of the most frequently mentioned names, because he was obviously ahead of his time in many fields of natural history, medicine, and various aspects of engineering. Quite a number of such developments took place in a small space like the iconic

Association of aescin with β- and γ-cyclodextrins studied by DFT calculations and spectroscopic methods

• Ana I. Ramos,
• Pedro D. Vaz,
• Susana S. Braga and
• Artur M. S. Silva

Beilstein J. Nanotechnol. 2017, 8, 348–357, doi:10.3762/bjnano.8.37

• oleanoic [17][18][19], ursolic [18][19] and betulinic [18][20][21][22] acids. Ammonium glycyrrhizinate or glyciram (from licorice roots), sold in Russia and Japan as a natural anti-inflammatory, antiallergic and anti-spasmodic medicine, was also reported to become more stable against epoxidation upon

Microfluidic setup for on-line SERS monitoring using laser induced nanoparticle spots as SERS active substrate

• Oana-M. Buja,
• Ovidiu D. Gordan,
• Nicolae Leopold,
• Andreas Morschhauser,
• Jörg Nestler and
• Dietrich R. T. Zahn

Beilstein J. Nanotechnol. 2017, 8, 237–243, doi:10.3762/bjnano.8.26

• for Advanced Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Louis Pasteur 4–6, 400349 Cluj-Napoca, Romania Fraunhofer Institute for Electronic Nano Systems, Technologie-Campus 3, 09126 Chemnitz, Germany 10.3762/bjnano.8.26 Abstract A microfluidic setup which enables on-line monitoring

From iron coordination compounds to metal oxide nanoparticles

• Mihail Iacob,
• Carmen Racles,
• Codrin Tugui,
• George Stiubianu,
• Adrian Bele,
• Liviu Sacarescu,
• Daniel Timpu and
• Maria Cazacu

Beilstein J. Nanotechnol. 2016, 7, 2074–2087, doi:10.3762/bjnano.7.198

• exhibit different properties from their bulk form [2], numerous researchers became interested in discovering new properties and applications. Nanometer-sized iron oxides proved to be of interest in several fields such as medicine, applied physics, chemistry and engineering [3][4][5][6]. The interest in

• groups on the surface of nanoparticles [17][18] is useful for broadening the field of applications in medicine or catalysis [5][17]. Although there are currently numerous methods for the preparation of iron oxides nanoparticles, scientists are working to further improve existing methods and are

A novel electrochemical nanobiosensor for the ultrasensitive and specific detection of femtomolar-level gastric cancer biomarker miRNA-106a

• Maryam Daneshpour,
• Kobra Omidfar and
• Hossein Ghanbarian

Beilstein J. Nanotechnol. 2016, 7, 2023–2036, doi:10.3762/bjnano.7.193

• Maryam Daneshpour Kobra Omidfar Hossein Ghanbarian Biotechnology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran

• Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran 10.3762/bjnano.7.193 Abstract Gastric cancer (GC) is the second leading cause of cancer-related deaths all over the world. miR-106a is a circulatory oncogenic microRNA (miRNA), which overexpresses in various

Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling

• Nadezhda M. Zholobak,
• Anton L. Popov,
• Alexander B. Shcherbakov,
• Nelly R. Popova,
• Mykhailo M. Guzyk,
• Valeriy P. Antonovich,
• Alla V. Yegorova,
• Yuliya V. Scrypynets,
• Inna I. Leonenko,
• Alexander Ye. Baranchikov and
• Vladimir K. Ivanov

Beilstein J. Nanotechnol. 2016, 7, 1905–1917, doi:10.3762/bjnano.7.182

• centrifuged and rinsed three times with EDTA, and then three times with pure water. Cell cultures The effects of O-dots on living cells were studied using reference diploid epithelial swine testicular cell line (ST-cells), from the collection of the Institute of Veterinary Medicine, UAAS, and malignant breast

Low temperature co-fired ceramic packaging of CMOS capacitive sensor chip towards cell viability monitoring

• Niina Halonen,
• Joni Kilpijärvi,
• Maciej Sobocinski,
• Timir Datta-Chaudhuri,
• Antti Hassinen,
• Someshekar B. Prakash,
• Peter Möller,
• Pamela Abshire,
• Sakari Kellokumpu and
• Anita Lloyd Spetz

Beilstein J. Nanotechnol. 2016, 7, 1871–1877, doi:10.3762/bjnano.7.179

• of Oulu, Finland Department of Electrical & Computer Engineering and the Institute for Systems Research, University of Maryland, College Park, MD 20742, USA Faculty of Biochemistry and Molecular Medicine, University of Oulu, P.O. Box 5400, FI-90014 University of Oulu, Finland Advanced Design

Chitosan-based nanoparticles for improved anticancer efficacy and bioavailability of mifepristone

• Huijuan Zhang,
• Fuqiang Wu,
• Yazhen Li,
• Xiping Yang,
• Jiamei Huang,
• Tingting Lv,
• Yingying Zhang,
• Jianzhong Chen,
• Haijun Chen,
• Yu Gao,
• Guannan Liu and
• Lee Jia

Beilstein J. Nanotechnol. 2016, 7, 1861–1870, doi:10.3762/bjnano.7.178

• Huijuan Zhang Fuqiang Wu Yazhen Li Xiping Yang Jiamei Huang Tingting Lv Yingying Zhang Jianzhong Chen Haijun Chen Yu Gao Guannan Liu Lee Jia College of Chemistry, Fuzhou University, Fuzhou 350108, China School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350108, China

Influence of hydrothermal synthesis parameters on the properties of hydroxyapatite nanoparticles

• Sylwia Kuśnieruk,
• Jacek Wojnarowicz,
• Agnieszka Chodara,
• Tadeusz Chudoba,
• Stanislaw Gierlotka and
• Witold Lojkowski

Beilstein J. Nanotechnol. 2016, 7, 1586–1601, doi:10.3762/bjnano.7.153

• and investors. Hydroxyapatite is characterized by its biocompatibility and osteoconductivity. The material has been commonly and successfully used in regenerative medicine and in drug delivery systems [3][4]. Nanostructured hydroxyapatite particles can be applied as building blocks for damaged enamel

Development of adsorptive membranes by confinement of activated biochar into electrospun nanofibers

• Mehrdad Taheran,
• Mitra Naghdi,
• Satinder K. Brar,
• Emile Knystautas,
• Mausam Verma,
• Rao. Y. Surampalli and
• Jose. R. Valero

Beilstein J. Nanotechnol. 2016, 7, 1556–1563, doi:10.3762/bjnano.7.149

• effects on human health and environment. Chlortetracycline (CTC), a broad-spectrum antimicrobial agent, is commonly used as veterinary medicine for poultry, swine, and livestock [20]. This compound can enter the environment through the application of animal manure for agriculture, moving to rivers, ground

Antitumor magnetic hyperthermia induced by RGD-functionalized Fe₃O₄ nanoparticles, in an experimental model of colorectal liver metastases

• Oihane K. Arriortua,
• Eneko Garaio,
• Borja Herrero de la Parte,
• Maite Insausti,
• Luis Lezama,
• Fernando Plazaola,
• Jose Angel García,
• Jesús M. Aizpurua,
• Maialen Sagartzazu,
• Mireia Irazola,
• Nestor Etxebarria,
• Ignacio García-Alonso,
• Alberto Saiz-López and
• José Javier Echevarria-Uraga

Beilstein J. Nanotechnol. 2016, 7, 1532–1542, doi:10.3762/bjnano.7.147

• , University of the Basque Country, UPV/EHU, 48080, Bilbao, Spain Faculty of Medicine and Nursing, University of the Basque Country, UPV/EHU, P.O. Box 644, 48080, Bilbao, Spain BCMaterials, Basque Center for Materials, Applications and Nanostructures, 48160, Derio, Spain José Mari Korta Center, University of

Viability and proliferation of endothelial cells upon exposure to GaN nanoparticles

• Tudor Braniste,
• Ion Tiginyanu,
• Tibor Horvath,
• Simion Raevschi,
• Serghei Cebotari,
• Marco Lux,
• Axel Haverich and
• Andres Hilfiker

Beilstein J. Nanotechnol. 2016, 7, 1330–1337, doi:10.3762/bjnano.7.124

• Moldova 10.3762/bjnano.7.124 Abstract Nanotechnology is a rapidly growing and promising field of interest in medicine; however, nanoparticle–cell interactions are not yet fully understood. The goal of this work was to examine the interaction between endothelial cells and gallium nitride (GaN

On the pathway of cellular uptake: new insight into the interaction between the cell membrane and very small nanoparticles

• Claudia Messerschmidt,
• Daniel Hofmann,
• Anja Kroeger,
• Katharina Landfester,
• Volker Mailänder and
• Ingo Lieberwirth

Beilstein J. Nanotechnol. 2016, 7, 1296–1311, doi:10.3762/bjnano.7.121

• Claudia Messerschmidt Daniel Hofmann Anja Kroeger Katharina Landfester Volker Mailander Ingo Lieberwirth Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany Ostwestfalen-Lippe University of Applied Sciences, Liebigstr. 87, 32657 Lemgo, Germany Dept. of Medicine III

High antiviral effect of TiO₂·PL–DNA nanocomposites targeted to conservative regions of (−)RNA and (+)RNA of influenza A virus in cell culture

• Asya S. Levina,
• Marina N. Repkova,
• Elena V. Bessudnova,
• Ekaterina I. Filippova,
• Natalia A. Mazurkova and
• Valentina F. Zarytova

Beilstein J. Nanotechnol. 2016, 7, 1166–1173, doi:10.3762/bjnano.7.108

• Asya S. Levina Marina N. Repkova Elena V. Bessudnova Ekaterina I. Filippova Natalia A. Mazurkova Valentina F. Zarytova Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, pr. Lavrent’eva 8, Novosibirsk, 630090, Russia Institute of Catalysis

• subtypes of influenza A virus; TiO2·PL–DNA nanocomposites; Introduction The fundamental scientific problem of life sciences, especially modern molecular biology and fundamental medicine, is the development of approaches to the directed action on the genetic material of cells. Fragments of nucleic acids

• infectious, hereditary, cancer, and cardiovascular diseases is an important task of modern medicine and pharmacology. The selective recognition of molecular targets by NA-based therapeutics may minimize negative side effects compared to conventional pharmaceuticals that typically have less specificity

Multiwalled carbon nanotube hybrids as MRI contrast agents

• Nikodem Kuźnik and
• Mateusz M. Tomczyk

Beilstein J. Nanotechnol. 2016, 7, 1086–1103, doi:10.3762/bjnano.7.102

• nanotechnology crossing over domains of chemistry, physics, material science, engineering, biology and medicine has been somewhat harnessed to enhance both the quality and safety of human life. Parallel investigations at both a macroscopic and nano-/molecular level have already led, or at least are close to

• , myriads of applications. Medicine is one such field in which nanomaterials can help in therapy and diagnosis. Yet the unusual features of nanomaterials have raised natural concerns, especially regarding potential medical applications because of their exogenous origin and unknown physiology. Nevertheless

• carbon nanotubes (CNT) drug and genetic material delivery, immunotherapy or photothermal cancer therapy [1][2]. The 'quantum leap' [3] of bionanomaterials has also affected magnetic resonance imaging (MRI). This technique, which has already matured into a basic diagnostic tool in medicine, has an edge