Search results
Search for "HBOC" in Full Text gives 2 result(s) in Beilstein Journal of Nanotechnology.
Recognition mechanisms of hemoglobin particles by monocytes – CD163 may just be one
Beilstein J. Nanotechnol. 2023, 14, 1028–1040, doi:10.3762/bjnano.14.85
- might exist, independent of CD163 and also Hb. Keywords: CD163; HBOC; hemoglobin-based oxygen carriers; monocytes; phagocytosis; Introduction Blood transfusions save lives every day and have become an indispensable part of clinical practice in modern medicine. However, there have always been numerous
- HBOCs. This fits with a case report by Drieghe et al., which suggests that hemopexin (Hpx) may also play a role in the elimination of HBOCs [25][29]. Hpx was depleted before a change in Hp levels could be observed when catecholamine-requiring patients were treated with an HBOC for intentional NO
- scavenging and consecutive increase in peripheral vascular resistance. Whether binding between cell surface proteins and Hb/HBOC can occur, and how high the corresponding affinity is, probably depends on modifications made to Hb. Intramolecular crosslinking has an impact, depending on whether the binding
Bacterial safety study of the production process of hemoglobin-based oxygen carriers
Beilstein J. Nanotechnol. 2022, 13, 114–126, doi:10.3762/bjnano.13.8
- attracted particular attention in the last years. Many of the different approaches are using hemoglobin as a starting material to produce hemoglobin-based oxygen carriers (HBOC). Thus, hemoglobin from human and animal (especially bovine) sources or recombinant hemoglobin is used, which can then be
- chemically modified, cross-linked, polymerized, or encapsulated by various methods [1][2][3]. We produce biopolymer microparticles as HBOC with the simple coprecipitation–cross-linking–dissolution (CCD) technique while utilizing hemoglobin. Depending on the biopolymer used, there are also various other
Other Beilstein-Institut Open Science Activities
