Polyurethane/silk fibroin-based electrospun membranes for wound healing and skin substitute applications

• Iqra Zainab,
• Zohra Naseem,
• Syeda Rubab Batool,
• Muhammad Waqas,
• Ahsan Nazir and
• Muhammad Anwaar Nazeer

Beilstein J. Nanotechnol. 2025, 16, 591–612, doi:10.3762/bjnano.16.46

• more effective wound-healing substitutes [50]. Recent advancements in tissue regeneration have further led to the development of innovative wound dressings such as hydrogels and electrospun scaffolds [51]. Electrospinning is an extremely flexible technique that can convert liquids, suspensions, or

Nanomaterials in targeting amyloid-β oligomers: current advances and future directions for Alzheimer's disease diagnosis and therapy

• Shiwani Randhawa,
• Trilok Chand Saini,
• Manik Bathla,
• Rahul Bhardwaj,
• Rubina Dhiman and
• Amitabha Acharya

Beilstein J. Nanotechnol. 2025, 16, 561–580, doi:10.3762/bjnano.16.44

• specificity allow for efficient capture even at low concentrations, crucial in the complex biological environment of the brain. Recent advancements in immunoassay technology have led to the development of ultrasensitive methods for detecting Aβ-derived diffusible ligands (ADDLs) and AβOs. A novel immunoassay

• NPs led to a higher permeability of RA and CUR across the BBB. This suggests that the antibody plays a crucial role in improving the uptake of NPs by cells and drug delivery to the brain [65]. Additionally, antibody conjugation can help to reduce the immunogenicity of NPs, enhancing their safety and

• amyloid oligomers have led to side effects such as hydrocephalus, inflammation, and amyloid-related imaging abnormalities [90]. These side effects can be attributed to the activation of the complement system by the interaction of amyloid oligomers and antibodies, leading to the release of proinflammatory

Retrieval of B1 phase from high-pressure B2 phase for CdO nanoparticles by electronic excitations in Cd_xZn_1−xO composite thin films

• Arkaprava Das,
• Marcin Zając and
• Carla Bittencourt

Beilstein J. Nanotechnol. 2025, 16, 551–560, doi:10.3762/bjnano.16.43

• irradiation stability of the B2 phase through SHI with 120 MeV silver and 80 MeV oxygen ions, revealing distinct behaviors in response to each ion type. Silver ion irradiation was shown to induce amorphization in the B2 phase, while oxygen ion irradiation led to the notable recovery of the B1 phase. This

Water in nanoporous hexagonal boron nitride nanosheets: a first-principles study

• Juliana A. Gonçalves,
• Ronaldo J. C. Batista and
• Marcia C. Barbosa

Beilstein J. Nanotechnol. 2025, 16, 510–519, doi:10.3762/bjnano.16.39

• recent decades, technological advances such as membrane technology and energy recovery equipment have led to a considerable reduction in the energy required to desalinate seawater [2][3]. The proposal to use membranes that exhibit superior selectivity and high water flux has been a major focus for

N₂⁺-implantation-induced tailoring of structural, morphological, optical, and electrical characteristics of sputtered molybdenum thin films

• Usha Rani,
• Kafi Devi,
• Divya Gupta and
• Sanjeev Aggarwal

Beilstein J. Nanotechnol. 2025, 16, 495–509, doi:10.3762/bjnano.16.38

• lower thickness, the films exhibit higher tensile stress due to grain boundary contacts and point defects generated during the first phase of film growth. The increased thickness of films led to larger crystallites and improved crystallinity, which reduced tensile stress by decreasing atomic-scale

• to 300 nm also led to noticeable changes in morphology. With the increase in thickness, rough peaks evolved into broader and flatter shapes. The fast Fourier transform images indicate random distribution with different orientations of particles. The surface morphology parameters are listed in Table 3

Synthetic-polymer-assisted antisense oligonucleotide delivery: targeted approaches for precision disease treatment

• Ana Cubillo Alvarez,
• Dylan Maguire and
• Ruairí P. Brannigan

Beilstein J. Nanotechnol. 2025, 16, 435–463, doi:10.3762/bjnano.16.34

• . sLPD assemblies exhibited higher colloidal stability and cellular internalisation compared to free G3139 and non-stabilised counterparts. As a result, significantly higher inhibition of Bcl-2 proteins was observed in sLPD-treated groups, which led to induced apoptosis of KB cells and increased

• controlled release through disulfide bond cleavage [139]. Following dendrimer PEGylation (PEG5000 modified with a synthetic luteinizing-hormone-releasing hormone (LHRH) analogue) provided greater particle stability and active targeting to specific cancer cells, which led to increased intratumoral

Engineered PEG–PCL nanoparticles enable sensitive and selective detection of sodium dodecyl sulfate: a qualitative and quantitative analysis

• Soni Prajapati and
• Ranjana Singh

Beilstein J. Nanotechnol. 2025, 16, 385–396, doi:10.3762/bjnano.16.29

• through various pathways. This has led to significant concerns regarding developing rapid onsite qualitative and quantitative methods for estimating SDS in aqueous solutions. Although a range of high-throughput techniques is currently utilized for SDS quantification, these methods are often expensive

• sulfate group, with sodium as the counter-ion. The amphiphilic structure of SDS, integrating a hydrophobic alkyl chain and a hydrophilic headgroup, confers unique physicochemical properties that are leveraged in various applications. However, the widespread use of SDS in different applications led to the

Fabrication and evaluation of BerNPs regarding the growth and development of Streptococcus mutans

• Tuyen Huu Nguyen,
• Hong Thanh Pham,
• Kieu Kim Thanh Nguyen,
• Loan Hong Ngo,
• Anh Ngoc Tuan Mai,
• Thu Hoang Anh Lam,
• Ngan Thi Kim Phan,
• Dung Tien Pham,
• Duong Thuy Hoang,
• Thuc Dong Nguyen and
• Lien Thi Xuan Truong

Beilstein J. Nanotechnol. 2025, 16, 308–315, doi:10.3762/bjnano.16.23

• , ultimately triggering cell death [32]. The findings of Peng et al. on Streptococcus agalactiae indicated that berberine significantly disrupted the cell membrane structure. SDS-PAGE electrophoresis results showed that some protein bands were blurred or absent, suggesting that berberine led to complete or

Enhancing mechanical properties of chitosan/PVA electrospun nanofibers: a comprehensive review

• Nur Areisman Mohd Salleh,
• Amalina Muhammad Afifi,
• Fathiah Mohamed Zuki and
• Hanna Sofia SalehHudin

Beilstein J. Nanotechnol. 2025, 16, 286–307, doi:10.3762/bjnano.16.22

• chitosan/PVA nanofibers using dielectric barrier discharge (DBD) plasma and reported enhanced wettability, mechanical properties, and biocompatibility of the fibers. The argon and oxygen plasma treatments led to significant cross-linking of the fibers, which improved tensile strength and Young’s modulus

Emerging strategies in the sustainable removal of antibiotics using semiconductor-based photocatalysts

• Yunus Ahmed,
• Keya Rani Dutta,
• Parul Akhtar,
• Md. Arif Hossen,
• Md. Jahangir Alam,
• Obaid A. Alharbi,
• Hamad AlMohamadi and
• Abdul Wahab Mohammad

Beilstein J. Nanotechnol. 2025, 16, 264–285, doi:10.3762/bjnano.16.21

• with a suitable transition metal and synthesizing composite materials. Several advanced photocatalysts have been developed and successfully used to prevent antibiotics contamination, a list of which is shown below in Table 1. These modifications have led to improved charge separation rates, reduced

Radiosensitizing properties of dual-functionalized carbon nanostructures loaded with temozolomide

• Radmila Milenkovska,
• Nikola Geskovski,
• Dushko Shalabalija,
• Ljubica Mihailova,
• Petre Makreski,
• Dushko Lukarski,
• Igor Stojkovski,
• Maja Simonoska Crcarevska and
• Kristina Mladenovska

Beilstein J. Nanotechnol. 2025, 16, 229–251, doi:10.3762/bjnano.16.18

• . Such a trend was observed in a study of Jun et al. [47] in which MWCNTs conjugated with chitosan oligomers and with incorporated tea polyphenols for cancer treatment were irradiated by gamma rays from 60Co for 30 min with a dose of 1.5 Gy. The irradiation also led to changes in zeta potential to lower

• oxidation, the content of functional groups increased because of the increase in the effective surface for functionalization (or decrease in size) and the increase in number of defective sites on the MWCNTs created by the gamma photons. In addition, an exposure of SWCNTs to gamma radiation led to a

• significantly higher extent of functionalization with single-stranded DNA [64]. It was also shown that gamma radiation with low doses, 25 and 50 kGy, improved the graphite arrangement of MWCNTs; higher doses, 100 and 150 kGy, led to major structural deteriorations, while very high doses above 200 kGy distorted

Recent advances in photothermal nanomaterials for ophthalmic applications

• Jiayuan Zhuang,
• Linhui Jia,
• Chenghao Li,
• Rui Yang,
• Jiapeng Wang,
• Wen-an Wang,
• Heng Zhou and
• Xiangxia Luo

Beilstein J. Nanotechnol. 2025, 16, 195–215, doi:10.3762/bjnano.16.16

• damage to surrounding tissues due to inadequate control over the heat distribution [100][101][102][103][104][105]. Innovations in this field have led to the development of transparent polylactic acid (PLA) thin films with embedded iron oxide nanoclusters prepared via spin coating [51]. The efficient

• a frequent complication following ophthalmic surgery [146][147][148]. While antibiotics remain the most effective treatment against microbial infections, their global overuse has led to the emergence of drug-resistant bacterial strains [149][150][151]. In response, Zhou et al. developed a

• showed that ICG liposomes led to subtle disruption effects in the ILM, in which completely ablated ILM regions alternate with intact regions. Photoporation strategies to overcome the ILM have the potential to improve the efficacy of all retinal therapies impeded by ILM delivery barriers, including

A review of metal-organic frameworks and polymers in mixed matrix membranes for CO₂ capture

• Charlotte Skjold Qvist Christensen,
• Nicholas Hansen,
• Mahboubeh Motadayen,
• Nina Lock,
• Martin Lahn Henriksen and
• Jonathan Quinson

Beilstein J. Nanotechnol. 2025, 16, 155–186, doi:10.3762/bjnano.16.14

• synthesis [32]. The resulting constructions have pore sizes ranging from microporous (<2 nm) to mesoporous (2–50 nm) [30][36]. This simple strategy has led to substantial exploration of various MOFs with different structures and properties for various applications in heterogeneous catalysis, biomedicine

• displayed severe curling and exhibited poor MOF distributions, attributed to the prolonged evaporation times required, as well as the low viscosity and density of this solvent. In contrast, the MMMs produced in oxolane, dichloromethane, and chloroform led to generally well-formed MMMs with reasonable

• modification expanded the pore-limiting diameter marginally from 2.8 to 2.9 Å, while maintaining the overall MOF topology. This isoreticular fine-tuning led to an increase in CO2/N2 selectivity from 180 to 500 in simulations of a 15/85 binary CO2/N2 mixture at 1 bar and 293 K. Alternatively, incorporating pro

Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy

• Naths Grazia Sukubo,
• Paolo Bigini and
• Annalisa Morelli

Beilstein J. Nanotechnol. 2025, 16, 97–118, doi:10.3762/bjnano.16.10

• . Intranasal delivery has emerged as a promising strategy for targeting the central nervous system by bypassing the blood–brain barrier (BBB). This approach was demonstrated by the nose-to-brain administration of D6-cholestrol-loaded liposomes, which led to an accumulation of D6-cholesterol in the brain in

Characterization of ZnO nanoparticles synthesized using probiotic Lactiplantibacillus plantarum GP258

• Prashantkumar Siddappa Chakra,
• Aishwarya Banakar,
• Shriram Narayan Puranik,
• Vishwas Kaveeshwar,
• C. R. Ravikumar and
• Devaraja Gayathri

Beilstein J. Nanotechnol. 2025, 16, 78–89, doi:10.3762/bjnano.16.8

• peak current, though a steady addition led to decreased currents, possibly due to surface accumulation. The Nyquist plots display a larger impedance for ZnO electrodes. To fit the data into an analogous circuit, an uninterrupted phase element (Q1) was introduced with the adjustable parameters angular

Instance maps as an organising concept for complex experimental workflows as demonstrated for (nano)material safety research

• Benjamin Punz,
• Maja Brajnik,
• Joh Dokler,
• Jaleesia D. Amos,
• Litty Johnson,
• Katie Reilly,
• Anastasios G. Papadiamantis,
• Amaia Green Etxabe,
• Lee Walker,
• Diego S. T. Martinez,
• Steffi Friedrichs,
• Klaus M. Weltring,
• Nazende Günday-Türeli,
• Claus Svendsen,
• Christine Ogilvie Hendren,
• Mark R. Wiesner,
• Martin Himly,
• Iseult Lynch and
• Thomas E. Exner

Beilstein J. Nanotechnol. 2025, 16, 57–77, doi:10.3762/bjnano.16.7

• properties can be tailored by changing their size, shape, surface chemistry, and functionality, have led to the designation of nanomaterials as a key enabling technology and to their subsequent inclusion in the broader categorisation of advanced materials [1][2]. Applications of nanomaterials derive in many

A nanocarrier containing carboxylic and histamine groups with dual action: acetylcholine hydrolysis and antidote atropine delivery

• Elina E. Mansurova,
• Andrey A. Maslennikov,
• Anna P. Lyubina,
• Alexandra D. Voloshina,
• Irek R. Nizameev,
• Marsil K. Kadirov,
• Anzhela A. Mikhailova,
• Polina V. Mikshina,
• Albina Y. Ziganshina and
• Igor S. Antipin

Beilstein J. Nanotechnol. 2025, 16, 11–24, doi:10.3762/bjnano.16.2

• concentration range (13–1650 μM) and did not cause hemolysis even at the highest concentration of 825 μM (Table 2 and Supporting Information File 1, Figure S4). Hist-RA at 220 μM led to nearly 100% hemolysis (Supporting Information File 1, Figure S4), while at concentrations of 110 and 55 μM, agglutination was

Attempts to preserve and visualize protein corona on the surface of biological nanoparticles in blood serum using photomodification

• Julia E. Poletaeva,
• Anastasiya V. Tupitsyna,
• Alina E. Grigor’eva,
• Ilya S. Dovydenko and
• Elena I. Ryabchikova

Beilstein J. Nanotechnol. 2024, 15, 1654–1666, doi:10.3762/bjnano.15.130

• on the bio-NPs was lost during the isolation process. Long-term exposure of bio-NPs to 30% sucrose at 100,000g led to the disruption of their ultrastructure. Isolation on a sucrose cushion did not preserve the protein corona on EVs and LPs, but it did not damage their ultrastructure. In the samples

Facile synthesis of size-tunable L-carnosine-capped silver nanoparticles and their role in metal ion sensing and catalytic degradation of p-nitrophenol

• Akash Kumar,
• Ridhima Chadha,
• Abhishek Das,
• Nandita Maiti and
• Rayavarapu Raja Gopal

Beilstein J. Nanotechnol. 2024, 15, 1576–1592, doi:10.3762/bjnano.15.124

• temperature and the ratio of NaBH4 to NaOH led to the formation of ʟ-car-AgNPs with different colors. The color of the obtained nanoparticles suggested that they were in a controlled aggregated state. Further characterization was performed to analyze the physicochemical properties of the synthesized ʟ

• is assumed that the higher temperature, along with the ratio of NaOH to NaBH4, led to the formation of aggregated ʟ-car-AgNPs. These results contradict earlier reports and confirm the formation of aggregated ʟ-car-AgNPs with two absorption bands. However, despite the different shapes, absorption

• -AgNP1 led to the degradation of 0.25 mM P-NP within 90 s of the reaction, achieving a degradation efficiency of 95.5% (Figure 9a). In comparison, ʟ-car-AgNP2, ʟ-car-AgNP3, ʟ-car-AgNP4, and ʟ-car-AgNP5 achieved complete P-NP degradation within 100, 160, 140, and 220 s, respectively, with catalytic

Electrochemical nanostructured CuBTC/FeBTC MOF composite sensor for enrofloxacin detection

• Thi Kim Ngan Nguyen,
• Tien Dat Doan,
• Huy Hieu Luu,
• Hoang Anh Nguyen,
• Thi Thu Ha Vu,
• Quang Hai Tran,
• Ha Tran Nguyen,
• Thanh Binh Dang,
• Thi Hai Yen Pham and
• Mai Ha Hoang

Beilstein J. Nanotechnol. 2024, 15, 1522–1535, doi:10.3762/bjnano.15.120

• Ω and significantly better conductivity [37], to the (Cu)(Fe)BTC@CPE led to reduction to about a third in Rct. This reduction in charge transfer resistance is advantageous for the enhancement of electrochemical oxidation on the electrode surface. Electrochemical behaviour of enrofloxacin on the (Cu

Effect of radiation-induced vacancy saturation on the first-order phase transformation in nanoparticles: insights from a model

• Aram Shirinyan and
• Yuriy Bilogorodskyy

Beilstein J. Nanotechnol. 2024, 15, 1453–1472, doi:10.3762/bjnano.15.117

• effects led to a polymorphic phase change, transforming the high-density fcc structure to a low-density hexagonal close-packed crystallographic phase. The investigation of the radiation stability of nanocrystalline single-phase multicomponent alloys (NiFe, NiCoFe, and NiCoCr) using molecular dynamics

Ion-induced surface reactions and deposition from Pt(CO)₂Cl₂ and Pt(CO)₂Br₂

• Mohammed K. Abdel-Rahman,
• Patrick M. Eckhert,
• Atul Chaudhary,
• Johnathon M. Johnson,
• Jo-Chi Yu,
• Lisa McElwee-White and
• D. Howard Fairbrother

Beilstein J. Nanotechnol. 2024, 15, 1427–1439, doi:10.3762/bjnano.15.115

• techniques is that they produce deposits with relatively low metal contents as compared to CVD and ALD. Indeed, creating deposits with high metal contents is one of the biggest challenges for FIBID and FEBID, and recent advances in precursor design and fine-tuning of deposition parameters led to deposits of

Lithium niobate on insulator: an emerging nanophotonic crystal for optimized light control

• Midhun Murali,
• Amit Banerjee and
• Tanmoy Basu

Beilstein J. Nanotechnol. 2024, 15, 1415–1426, doi:10.3762/bjnano.15.114

• ]. However, a major challenge in their development is maximizing the light that escapes the micro-LED. By incorporating a DBR onto the bottom of a flip-chip micro-LED, engineers can capture light that would normally be lost downward and redirect it upwards, significantly improving the overall light output

Nanotechnological approaches for efficient N2B delivery: from small-molecule drugs to biopharmaceuticals

• Selin Akpinar Adscheid,
• Akif E. Türeli,
• Nazende Günday-Türeli and
• Marc Schneider

Beilstein J. Nanotechnol. 2024, 15, 1400–1414, doi:10.3762/bjnano.15.113

• revealed that an increase in particle size led to a shift towards caveolae-mediated internalization, the primary pathway for particles sized around 500 nm [69]. This shows the possibility of an even more extended particle size range to be considered for N2B delivery [69]. Regarding surface characteristics

• administration. The optimization process yielded optimized NLCs with a particle size of 178 nm of and an entrapment efficiency of 77%. The in vivo pharmacokinetic study showed that intranasal administration of the optimized NLC formulation led to significantly faster drug absorption and greater clozapine

• monoclonal antibody onto the NPs led to an increase in particle size and influenced the distribution of NPs in the hippocampus, indicating another critical factor for N2B delivery, namely, the particle size of NPs [153]. In another study with mAbs, Ferreira et al. developed and optimized a system of PLGA and

Various CVD-grown ZnO nanostructures for nanodevices and interdisciplinary applications

• The-Long Phan,
• Le Viet Cuong,
• Vu Dinh Lam and
• Ngoc Toan Dang

Beilstein J. Nanotechnol. 2024, 15, 1390–1399, doi:10.3762/bjnano.15.112

• comparison to other compounds [4][5][6]. Specifically, its large bandgap energy Eg ≈ 3.4 eV is comparable to GaN – a typical material for blue-light-emitting diode (LED) technology [7][8]. Also, its exciton binding energy is higher than the thermal energy at 300 K, and it has high-quality optical