Instance maps as an organising concept for complex experimental workflows as demonstrated for (nano)material safety research

• Benjamin Punz,
• Maja Brajnik,
• Joh Dokler,
• Jaleesia D. Amos,
• Litty Johnson,
• Katie Reilly,
• Anastasios G. Papadiamantis,
• Amaia Green Etxabe,
• Lee Walker,
• Diego S. T. Martinez,
• Steffi Friedrichs,
• Klaus M. Weltring,
• Nazende Günday-Türeli,
• Claus Svendsen,
• Christine Ogilvie Hendren,
• Mark R. Wiesner,
• Martin Himly,
• Iseult Lynch and
• Thomas E. Exner

Beilstein J. Nanotechnol. 2025, 16, 57–77, doi:10.3762/bjnano.16.7

• polyvinylpyrrolidone (PVP) surface by reduction of silver nitrate in ethylene glycol with 10k PVP. The PVP-AgNPs are characterised regarding some of their physical attributes such as the particles’ shape, size, and crystalline phase. The particles are then sulfidised using different specified concentrations of the PVP

The round-robin approach applied to nanoinformatics: consensus prediction of nanomaterials zeta potential

• Dimitra-Danai Varsou,
• Arkaprava Banerjee,
• Joyita Roy,
• Kunal Roy,
• Giannis Savvas,
• Haralambos Sarimveis,
• Ewelina Wyrzykowska,
• Mateusz Balicki,
• Tomasz Puzyn,
• Georgia Melagraki,
• Iseult Lynch and
• Antreas Afantitis

Beilstein J. Nanotechnol. 2024, 15, 1536–1553, doi:10.3762/bjnano.15.121

• CuO) were represented as 0 and metals (e.g., Ag, Au, and Cu) were represented as 1. For the shape group descriptor, the string names “Spherical”, “Square Plates” and “Rod” were one-hot encoded. Lastly, out of 22 unique coatings, five categories were created (sodium citrate, ʟ-arginine, PVP, uncoated

Nanoarchitectonics with cetrimonium bromide on metal nanoparticles for linker-free detection of toxic metal ions and catalytic degradation of 4-nitrophenol

• Akash Kumar and
• Raja Gopal Rayavarapu

Beilstein J. Nanotechnol. 2024, 15, 1312–1332, doi:10.3762/bjnano.15.106

• agents on the metal surface and further dominates functionalization. Various capping agents such as citrate, PVP, and surfactants have been the choice for metal nanoparticles. Controlled size, shape, and surface properties have been achieved using strong capping and reducing agents. Capping agents

Effect of wavelength and liquid on formation of Ag, Au, Ag/Au nanoparticles via picosecond laser ablation and SERS-based detection of DMMP

• Sree Satya Bharati Moram,
• Chandu Byram and
• Venugopal Rao Soma

Beilstein J. Nanotechnol. 2024, 15, 1054–1069, doi:10.3762/bjnano.15.86

• , cetyltrimethylammonium chloride (CTAC), polyvinylpyrrolidone (PVP), and sodium dodecyl sulfate (SDS). Their outcomes revealed that the productivity of Ag NPs was higher in acetone, followed by CTAC, water, PVP, and SDS. The order of NP formation efficiency was reported to be acetone >CTAC >water >PVP >SDS. Morphological

Electrospun polysuccinimide scaffolds containing different salts as potential wound dressing material

• Veronika Pálos,
• Krisztina S. Nagy,
• Rita Pázmány,
• Krisztina Juriga-Tóth,
• Bálint Budavári,
• Judit Domokos,
• Dóra Szabó,
• Ákos Zsembery and
• Angela Jedlovszky-Hajdu

Beilstein J. Nanotechnol. 2024, 15, 781–796, doi:10.3762/bjnano.15.65

• al. investigated polyvinylpyrrolidone (PVP) film doped with silver and zinc oxide nanoparticles. They reported that the presence of the nanoparticles increased the fiber diameter of the PVP polymer film [47]. Evaluation of mechanical tests For wound dressing applications, mechanical properties

On the additive artificial intelligence-based discovery of nanoparticle neurodegenerative disease drug delivery systems

• Shan He,
• Julen Segura Abarrategi,
• Harbil Bediaga,
• Sonia Arrasate and
• Humberto González-Díaz

Beilstein J. Nanotechnol. 2024, 15, 535–555, doi:10.3762/bjnano.15.47

• ) and n(cn4) = 16 coating agents (UC, PEG-Si(OMe)3, PVA, sodium citrate, 11-mercaptoundecanoic acid, PVP, propylamonium fragment, undecylazide fragment, CTAB, N,N,N-trimethyl-3(1-propene) ammonium fragment, potato starch, N-acetylcysteine, CMC-90, 2,3-dimercaptopropanesulfonate, 3

• = guanidinonaltrindole, 12 = semagacestat, 13 = huprine X, 14= carproctamide, 15= tacrine, 16 = tramiprosate, 17 = preladenant, 18 = piracetam, 19 = istradefylline, and 20 = rivastigmine. These systems include the following coating agents: PEG = polyethylene glycol, PVP = polyvinylpyrrolidone, PPF = propylammonium

Plasmonic nanotechnology for photothermal applications – an evaluation

• A. R. Indhu,
• L. Keerthana and
• Gnanaprakash Dharmalingam

Beilstein J. Nanotechnol. 2023, 14, 380–419, doi:10.3762/bjnano.14.33

Enhanced electronic transport properties of Te roll-like nanostructures

• E. R. Viana,
• N. Cifuentes and
• J. C. González

Beilstein J. Nanotechnol. 2022, 13, 1284–1291, doi:10.3762/bjnano.13.106

• charges have been studied in p-type Te NBs [13]. In this work, we have studied the electronic transport properties of a distinct one-dimensional t-Te nanostructure with a roll-like morphology, which resembles cinnamon sticks. The nanostructures were obtained by a facile PVP-assisted hydrothermal route

• environmentally friendly solvothermal method by the reduction of Na2TeO3 and passivation with polyvinylpyrrolidone (PVP), as reported elsewhere [15]. The procedure described by Wu et al. [15] for the synthesis of Te NWs was followed, with the modification of increasing the autoclave heating to 200 °C. All

Application of nanoarchitectonics in moist-electric generation

• Jia-Cheng Feng and
• Hong Xia

Beilstein J. Nanotechnol. 2022, 13, 1185–1200, doi:10.3762/bjnano.13.99

• available in MEGs, such as polymers, proteins, and natural fibers, poly(4-vinylphenol) (PVP) [75], polyvinyl alcohol (PVA) [76][77], fluorinated ethylene propylene (FEP) [21], and polyvinylidene difluoride (PVDF). These materials show good performance in the application of hydropower conversion. In addition

• , there are also some novel innovations in energy-harvesting structures, such as the construction of lateral gradients of nanomaterials, the construction of multilayer structures, and the direct use of ion distribution gradients in liquids. With a PVP thin film of 290 nm thickness as the dielectric layer

Microneedle-based ocular drug delivery systems – recent advances and challenges

• Piotr Gadziński,
• Anna Froelich,
• Monika Wojtyłko,
• Antoni Białek,
• Julia Krysztofiak and
• Tomasz Osmałek

Beilstein J. Nanotechnol. 2022, 13, 1167–1184, doi:10.3762/bjnano.13.98

• if the needles break and are deposited in the tissue [117][118]. Other non-degradable materials utilized to fabricate microneedles, include metals such as stainless steel [119] and titanium [120], ceramics, such as aluminum oxide [121], or synthetic polymers comprising polyvinylpyrrolidone (PVP) [122

• glaucoma, was developed by Roy et al. The MN matrix consisted of PVA and PVP and contained 1 mg of the drug. The patches were fabricated by micromolding and mimicked the shape of commercial contact lenses (Figure 4). The patches were tested ex vivo with the use of excised human cornea and porcine eye globe

• numerous inflammatory conditions to the posterior segment of the eye. A microneedle scleral patch (MSP) and a microneedle corneal patch (MCP) were obtained by micromolding with the use of PVP. The ex vivo experiments performed on porcine eye globe showed that, in comparison to MCP and TA nanosuspension

Electrocatalytic oxygen reduction activity of AgCoCu oxides on reduced graphene oxide in alkaline media

• Iyyappan Madakannu,
• Indrajit Patil,
• Bhalchandra Kakade and
• Kasibhatta Kumara Ramanatha Datta

Beilstein J. Nanotechnol. 2022, 13, 1020–1029, doi:10.3762/bjnano.13.89

• electrocatalyst. Results and Discussion The microwave-assisted one-pot synthesis connecting graphene oxide (GO) nanosheets with bi- and trimetallic precursors under alkaline conditions is presented in Figure 1. GO serves as functional network and conducting matrix, while PVP acts as structure-directing agent

Influence of thickness and morphology of MoS₂ on the performance of counter electrodes in dye-sensitized solar cells

• Lam Thuy Thi Mai,
• Hai Viet Le,
• Ngan Kim Thi Nguyen,
• Van La Tran Pham,
• Thu Anh Thi Nguyen,
• Nguyen Thanh Le Huynh and
• Hoang Thai Nguyen

Beilstein J. Nanotechnol. 2022, 13, 528–537, doi:10.3762/bjnano.13.44

• %), valeronitrile (CH3(CH2)3CN, 99.5%), chloroplatinic acid hexahydrate (H2PtCl6·6H2O, ≥37.50% Pt), sulfuric acid (H2SO4, 95–98%), polyvinylpyrrolidone (PVP, (C6H9NO)n, average Mw 10,000), and sodium borohydride (NaBH4, 99%) were purchased from Sigma-Aldrich (Germany). Low-temperature thermoplastic sealant (Surlyn

• , a Pt-based CE (Pt/FTO) was fabricated by soaking the cleaned FTO glasses in PVP–platinum suspension at 45 °C for 5 min, followed by washing with distilled water. The PVP–platinum suspension was prepared as follows: First, 1.0 g of H2PtCl6 was dissolved in 150 mL of distilled water, then 0.5 g PVP

Ciprofloxacin-loaded dissolving polymeric microneedles as a potential therapeutic for the treatment of S. aureus skin infections

• Sharif Abdelghany,
• Walhan Alshaer,
• Yazan Al Thaher,
• Maram Al Fawares,
• Amal G. Al-Bakri,
• Saja Zuriekat and
• Randa SH. Mansour

Beilstein J. Nanotechnol. 2022, 13, 517–527, doi:10.3762/bjnano.13.43

• dissolving polymeric microneedles prepared by a two-layer centrifugation method as a potential treatment of skin infections such as cellulitis. The polymers used were polyvinyl alcohol (PVA) and polyvinylpyrrolidone (PVP). Two formulations were investigated, namely CIP_MN1, composed of 10 mg ciprofloxacin

• incorporated into a polymer matrix of PVA and PVP with a weight ratio of (9:1), and CIP_MN2, composed of 10 mg ciprofloxacin incorporated into PVA polymer. CIP_MN1 and CIP_MN2 showed a mean microneedle height of 188 and 179 µm, respectively. Since Parafilm has been proven as a model to examine the perforation

• results suggest that CIP_MN1 can be a potential delivery system for the treatment of S. aureus skin infections. Keywords: dissolving microneedles; microneedles; polyvinyl alcohol (PVA); polyvinylpyrrolidone (PVP); skin infection; Introduction Topical and transdermal drug delivery is a major route for

Design and characterization of polymeric microneedles containing extracts of Brazilian green propolis

• Camila Felix Vecchi,
• Rafaela Said dos Santos,
• Jéssica Bassi da Silva and
• Marcos Luciano Bruschi

Beilstein J. Nanotechnol. 2022, 13, 503–516, doi:10.3762/bjnano.13.42

• and lower toxicity [26][27]. In our previous studies, polymeric systems composed of polyvinyl alcohol (PVA), polyvinylpyrrolidone (PVP), and poloxamer 407 (P407) were obtained and characterized. P407 could improve structuring and rapid dispersion of polymeric matrices, which showed promising

• physicochemical characteristics for potential application as nanostructured platforms for controlled drug delivery [28][29][30]. To our knowledge, MNs containing PRP have not been proposed before. Therefore, the aim of this study was to design microneedles composed of PVA, PVP, and P407 for the delivery of

• time, the design of MNs composed of PVA, PVP, and P407 as a polymeric platform for the delivery of alcoholic and glycolic green propolis extracts. MN formulations were characterized regarding their morphology, dimensions, and mechanical properties. Selected MN formulations (E3, E6, E9, and G6

Photothermal ablation of murine melanomas by Fe₃O₄ nanoparticle clusters

• Xue Wang,
• Lili Xuan and
• Ying Pan

Beilstein J. Nanotechnol. 2022, 13, 255–264, doi:10.3762/bjnano.13.20

• micelles and the formation of Fe3O4 nanoparticle clusters, which were then coated with polyvinylpyrrolidone (PVP) to improve stability, biocompatibility and chemical features of the nanoparticles. Further SEM measurements revealed the as-formed Fe3O4 NPCs to be spherical and uniformly sized with an average

• acetylacetonate (Fe(acac)3, 99.9+%), dibenzyl ether (99%), oleic acid (90%), oleylamine (>70%), dodecyltrimethylammonium bromide (DTAB, 99%), tetradecyltrimethylammonium bromide (TTAB, 99%), and polyvinylpyrrolidone (PVP, molecular weight 58,000) were purchased from Sigma-Aldrich. Decayltrimethylammonium bromide

• ethanol and dispersed in chloroform at a concentration of 1 mg/mL for later use. Synthesis of clustered Fe3O4 nanoparticles Step 1: PVP (0.58 g, molecular weight 58,000) was dissolved in 5 mL ethylene glycol under magnetic stirring. Step 2: DTAB or TTAB or DeTAB (0.02 g) were dissolved in 1 mL pure water

A comprehensive review on electrospun nanohybrid membranes for wastewater treatment

• Senuri Kumarage,
• Imalka Munaweera and
• Nilwala Kottegoda

Beilstein J. Nanotechnol. 2022, 13, 137–159, doi:10.3762/bjnano.13.10

• into cross-linked polyvinylpyrrolidone (PVP) [15]. ENH membranes, along with their high porosity and high aspect ratio, possess a high permeation ability, adsorbability, and selectivity, which makes them excellent for environmental remediation, specifically for the adsorption and filtration of

• membrane to remove Pb2+ and Cu2+ ions from aqueous solutions by electrospinning PVP and 3-mercaptopropyltrimethoxysilane (TMPTMS) infused with cerium oxide [62]. Also, they have modified the PVP/CeO2/TMPTMS nanofibers with a surfactant (Pluronic123) to obtain smaller fiber diameters and greater pore volume

• and average pore diameters. The analysis showed that PVP/CeO2/TMPTMS/P123 had a five times larger surface area than PVP/CeO2, which resulted in a maximum adsorption capacity of 272.3 mg/g for Pb2+ and 263.4 mg/g for Cu2+ ion, approximately three times greater than the adsorption capacity of PVP/CeO2

Tin dioxide nanomaterial-based photocatalysts for nitrogen oxide oxidation: a review

• Viet Van Pham,
• Hong-Huy Tran,
• Thao Kim Truong and
• Thi Minh Cao

Beilstein J. Nanotechnol. 2022, 13, 96–113, doi:10.3762/bjnano.13.7

• , nanobelts, and nanotubes. These morphologies can be controllably obtained by using polyvinylpyrrolidone (PVP), sodium dodecyl sulfonate (SDS), cetyl trimethyl ammonium bromide (CTAB), or tetrapropyl ammonium bromide (TPAB) as surfactants in a hydrothermal method [56][57][58][59]. The difference of

Electrical, electrochemical and structural studies of a chlorine-derived ionic liquid-based polymer gel electrolyte

• Ashish Gupta,
• Amrita Jain,
• Manju Kumari and
• Santosh K. Tripathi

Beilstein J. Nanotechnol. 2021, 12, 1252–1261, doi:10.3762/bjnano.12.92

• -dimethylimidazolium chloride ([BDiMIM][Cl]), tested its application in polymer electrolytes, and obtained a maximum room-temperature conductivity of 2.7 × 10−6 S·cm−1. Among various polymer matrix systems, such as polyethylene oxide (PEO) [18][19], polyvinyl alcohol (PVA) [20][21], and polyvinylpyrrolidone (PVP) [22

An overview of microneedle applications, materials, and fabrication methods

• Zahra Faraji Rad,
• Philip D. Prewett and
• Graham J. Davies

Beilstein J. Nanotechnol. 2021, 12, 1034–1046, doi:10.3762/bjnano.12.77

• microneedles of soluble poly(lactic-co-glycolic acid) (PLGA) and PLGA–polyvinylpyrrolidone (PLGA–PVP) layered combinations have been used to provide controlled drug delivery of bovine serum albumin (BSA), rather than instantaneous release [60]. There are only a few published studies demonstrating the

Progress and innovation of nanostructured sulfur cathodes and metal-free anodes for room-temperature Na–S batteries

• Marina Tabuyo-Martínez,
• Bernd Wicklein and
• Pilar Aranda

Beilstein J. Nanotechnol. 2021, 12, 995–1020, doi:10.3762/bjnano.12.75

• consisting of choline chloride and Na2S2O3 [61]. This cathode material retained 900 mAh·g−1 over 100 cycles. A modified precipitation method for S NPs is flash nanoprecipitation using a confined impingement jet mixer, in which Na2S2O3, H2O, HCl, and a stabilizing copolymer (polyvinylpyrrolidone, PVP) form

• sub-micrometer-sized sulfur NPs within milliseconds [62]. The resulting sulfur–PVP composite cathode had a capacity of 808 mAh·g−1 after 50 cycles at 0.1C. Sodium metal-free anodes The reason for the widespread use of metal Na anodes in Na–S batteries is the very high capacity of 1165 mAh·g−1 of

Silver nanoparticles nucleated in NaOH-treated halloysite: a potential antimicrobial material

• Yuri B. Matos,
• Rodrigo S. Romanus,
• Mattheus Torquato,
• Edgar H. de Souza,
• Rodrigo L. Villanova,
• Marlene Soares and
• Emilson R. Viana

Beilstein J. Nanotechnol. 2021, 12, 798–807, doi:10.3762/bjnano.12.63

• the industrial mass-production of Ag-NPs. Amongst the most scalable synthesis routes for Ag-NPs, some techniques stand out by using stabilizers, such as PVP [13] or PEG [14] capping agents, to ensure that silver nucleates and stabilizes into nanosized particles, instead of dissolving back into Ag

Fate and transformation of silver nanoparticles in different biological conditions

• Barbara Pem,
• Marija Ćurlin,
• Darija Domazet Jurašin,
• Valerije Vrček,
• Rinea Barbir,
• Vedran Micek,
• Raluca M. Fratila,
• Jesus M. de la Fuente and
• Ivana Vinković Vrček

Beilstein J. Nanotechnol. 2021, 12, 665–679, doi:10.3762/bjnano.12.53

• ]. Here, we exposed Wistar rats to poly(vinylpyrrolidone) (PVP)-coated AgNPs for 28 days. A microscopic examination of liver tissues of treated animals revealed an interesting result (described below) that initiated our subsequent research (presented here) on a possible transformation pattern of AgNPs in

• absorption spectroscopy (GF-AAS), nuclear magnetic resonance (NMR) spectroscopy, and transmission electron microscopy (TEM) experiments. Physicochemical characteristics of freshly prepared AgNPs Freshly prepared AgNPs coated with PVP, sodium bis(2-ethylhexyl)sulfosuccinate (AOT), and poly(ʟ-lysine) (PLL

• percentage of 20 nm particles in the case of AOT- and PVP-coated AgNPs. The major difference between different AgNPs was their potential values ζ, which were consistent with the charges of coating molecules used for their decoration. The ζ potential of AOT-AgNPs was strongly negative (−35.8 ± 6.9 mV), while

High-yield synthesis of silver nanowires for transparent conducting PET films

• Gul Naz,
• Hafsa Asghar,
• Muhammad Ramzan,
• Muhammad Arshad,
• Rashid Ahmed,
• Muhammad Bilal Tahir,
• Bakhtiar Ul Haq,
• Nadeem Baig and
• Junaid Jalil

Beilstein J. Nanotechnol. 2021, 12, 624–632, doi:10.3762/bjnano.12.51

• (AgNWs) with ultrahigh purity and high yield were successfully synthesized by employing a modified facile polyol method using PVP as a capping and stabilizing agent. The reaction was carried out at a moderate temperature of 160 °C under mild stirring for about 3 h. The prepared AgNWs exhibited parallel

• ]. This method involves the reduction of metallic salts in the presence of a polyol. This synthetic method was first proposed by Figlarz and co-workers for the synthesis of rod-like silver particles. They employed ethylene glycol as polyol to reduce silver salt in the presence of polyvinylpyrrolidone (PVP

• synthesis, ethylene glycol was used as a reducing agent in the presence of PVP as capping agent. Silver nitrate and CuCl2 were used as sources of silver and metallic salt, respectively. The resultant nanowires grew 3.3–4.7 µm in length and 75–97 nm in diameter. A silver nanowire ink was then transferred to

A review on nanostructured silver as a basic ingredient in medicine: physicochemical parameters and characterization

• Gabriel M. Misirli,
• Kishore Sridharan and
• Shirley M. P. Abrantes

Beilstein J. Nanotechnol. 2021, 12, 440–461, doi:10.3762/bjnano.12.36

• polyol synthesis method involves the reduction of a metal salt in the presence of a boiling solvent at elevated temperatures (>160 °C). In order to protect the nucleated particles and avoid agglomeration, the most commonly used adjuvant is PVP [139]. One of the advantages of this method is that ethylene

• , due to the fact that the silver ion does not absorb in the visible region [55][63]. Zhang et al. carried out a systematic study of the production of spherical AgNPs with PVP and citrate. The reactions produced spherical AgNPs which exhibited an acute plasmon resonance peak at ≈400 nm in the UV–vis

• absorption spectrum. However, by modifying the reaction medium with peroxide, citrate, and PVP they noticed the formation of AgNPs in the form of nanoplates, which had an absorption peak at ≈560 nm [151]. Gustav Mie was the first to rigorously explain the colors exhibited by metal colloids by using Maxwell's

Characterization, bio-uptake and toxicity of polymer-coated silver nanoparticles and their interaction with human peripheral blood mononuclear cells

• Sahar Pourhoseini,
• Reilly T. Enos,
• Angela E. Murphy,
• Bo Cai and
• Jamie R. Lead

Beilstein J. Nanotechnol. 2021, 12, 282–294, doi:10.3762/bjnano.12.23

• of issues such as poor control of NP properties and lack of proper characterization. The aim of this study was to investigate the combined characterization, bio-uptake, and toxicity of well-characterized polyvinylpyrrolidone (PVP)-coated AgNPs in exposure media during exposure time using primary

• dissolved Ag in PBMCs to distinguish between the effects of metallic Ag and metal ions. In addition, we investigated if there was significant variability across different individuals during various comparisons. Results PVP-AgNP characterization In this study we used a multimethod approach to characterize

• 0.18, indicating an acceptably monodisperse particle suspension and an absence of larger agglomerates in ultrahigh-purity water (UHPW) (Table 1). A representative curve is shown in Supporting Information File 1, Figure S1a. The zeta potential was measured as −23.3 ± 2.1 mV for PVP-coated AgNPs (PVP