A calix[4]arene-based supramolecular nanoassembly targeting cancer cells and triggering the release of nitric oxide with green light

• Cristina Parisi,
• Loredana Ferreri,
• Tassia J. Martins,
• Francesca Laneri,
• Samantha Sollima,
• Antonina Azzolina,
• Antonella Cusimano,
• Nicola D’Antona,
• Grazia M. L. Consoli and
• Salvatore Sortino

Beilstein J. Nanotechnol. 2025, 16, 1003–1013, doi:10.3762/bjnano.16.75

• activatable with blue light, and encouraging the NO release with the more biocompatible green light probably by an intra-cage photoinduced electron transfer. Keywords: calixarenes; cell targeting; fluorescence; light; nitric oxide; Introduction Calix[n]arenes are a family of polyphenolic macrocycles

• , characterized by the presence of a cavity with remarkable hosting properties and synthetic versatility [1][2][3][4][5]. Water soluble calixarenes can be obtained by the introduction of appropriate hydrophilic moieties in the calixarene molecular scaffold, leading to a good biocompatibility and low

A nanocarrier containing carboxylic and histamine groups with dual action: acetylcholine hydrolysis and antidote atropine delivery

• Elina E. Mansurova,
• Andrey A. Maslennikov,
• Anna P. Lyubina,
• Alexandra D. Voloshina,
• Irek R. Nizameev,
• Marsil K. Kadirov,
• Anzhela A. Mikhailova,
• Polina V. Mikshina,
• Albina Y. Ziganshina and
• Igor S. Antipin

Beilstein J. Nanotechnol. 2025, 16, 11–24, doi:10.3762/bjnano.16.2

• calixarenes, have been extensively utilized in the creation of different smart systems [13][14]. Owing to their unique structural features, these macrocycles are employed in catalysis, such as in the breakdown of OPs [15][16][17][18], as carriers for drug delivery [19][20][21][22], and in the creation of

Design of surface nanostructures for chirality sensing based on quartz crystal microbalance

• Yinglin Ma,
• Xiangyun Xiao and
• Qingmin Ji

Beilstein J. Nanotechnol. 2022, 13, 1201–1219, doi:10.3762/bjnano.13.100

• sensibility. Calixarenes. Chiral calixarenes are a class of important host compounds which have wide applications in chiral recognition, enantiomer separation, and asymmetrical catalysis [70][71][72]. Calix[4]arene compounds are the most investigated molecules due to their stable bowl-shaped conformation and

• easy derivatization. The intramolecular cavities of calixarenes are known to be able to selectively interact with structurally complementary molecular species for molecular recognition purposes. Chirality in calixarenes may derive from binding (at least) one chiral subunit to the rims or asymmetric

• placement of achiral subunits on the macrocycle [73][74][75]. Akpinar et al. reported a simple and quick chiral discrimination strategy for ascorbic acid (AA) enantiomers based on calixarenes films (Figure 6) [76]. A chiral calix[4]arene-bearing chiral phenyl glycinol moiety on the lower rim and a thiol

Multilayer capsules made of weak polyelectrolytes: a review on the preparation, functionalization and applications in drug delivery

• Varsha Sharma and
• Anandhakumar Sundaramurthy

Beilstein J. Nanotechnol. 2020, 11, 508–532, doi:10.3762/bjnano.11.41

• found within the supramolecular assemblies. Supramolecular polymers such as cyclodextrins, calixarenes, resorcinarenes and crown ethers play as host monomer units. The cup-like shape of calixerene, resorcinarenes units represents the host for their homoditopic or heterodipotic structures, i.e., two

• capsules is host–guest interactions as in the case of polymers such as cyclodextrins, calixarenes, resorcinarenes and crown ethers, wherein they play as host monomer units [59][86]. Such capsules made from strong PE assemblies showed pH switchable on–off capability of the polymers without breaking their

Charged particle single nanometre manufacturing

• Philip D. Prewett,
• Cornelis W. Hagen,
• Claudia Lenk,
• Steve Lenk,
• Marcus Kaestner,
• Tzvetan Ivanov,
• Ahmad Ahmad,
• Ivo W. Rangelow,
• Xiaoqing Shi,
• Stuart A. Boden,
• Alex P. G. Robinson,
• Dongxu Yang,
• Sangeetha Hari,
• Marijke Scotuzzi and
• Ejaz Huq

Beilstein J. Nanotechnol. 2018, 9, 2855–2882, doi:10.3762/bjnano.9.266

Nanoconjugates of a calixresorcinarene derivative with methoxy poly(ethylene glycol) fragments for drug encapsulation

• Alina M. Ermakova,
• Julia E. Morozova,
• Yana V. Shalaeva,
• Victor V. Syakaev,
• Aidar T. Gubaidullin,
• Alexandra D. Voloshina,
• Vladimir V. Zobov,
• Irek R. Nizameev,
• Olga B. Bazanova,
• Igor S. Antipin and
• Alexander I. Konovalov

Beilstein J. Nanotechnol. 2018, 9, 2057–2070, doi:10.3762/bjnano.9.195

• near the hydrophobic core, whereas the shell, which is composed of hydrophilic groups, ensures the stability of the system in solution. Examples for these amphiphilic compounds are surfactants [1], liposomes [2], polymers [3], and synthetic macrocycles [4]. Calixarenes and calixresorcinarenes are

• higher population of ending groups than linear polymers. Earlier, syntheses of amphiphilic derivatives of calixarenes and oligolactic acid [10][11], calixarenes and PEG [12][13][14][15][16][17][18], calixarene and calixresorcinarene polylactides [19] and polycaprolactones [20][21], as well as block

Self-assembly of chiral fluorescent nanoparticles based on water-soluble L-tryptophan derivatives of p-tert-butylthiacalix[4]arene

• Pavel L. Padnya,
• Irina A. Khripunova,
• Olga A. Mostovaya,
• Timur A. Mukhametzyanov,
• Vladimir G. Evtugyn,
• Vyacheslav V. Vorobev,
• Yuri N. Osin and
• Ivan I. Stoikov

Beilstein J. Nanotechnol. 2017, 8, 1825–1835, doi:10.3762/bjnano.8.184

• difference in emission wavelengths for the two calixarenes with bulk Boc groups in the tryptophan nitrogen atom, which differ only in the linker length between the macrocyclic and tryptophan parts. Therefore, we assert that only the length of the linker exerts an influence on the emission spectra. There is