Enhancing mechanical properties of chitosan/PVA electrospun nanofibers: a comprehensive review

• Nur Areisman Mohd Salleh,
• Amalina Muhammad Afifi,
• Fathiah Mohamed Zuki and
• Hanna Sofia SalehHudin

Beilstein J. Nanotechnol. 2025, 16, 286–307, doi:10.3762/bjnano.16.22

• industrial applications. It begins by outlining the fundamental properties of chitosan and PVA, highlighting their compatibility and mechanical characteristics. The electrospinning process is discussed, focusing on how various parameters and post-treatment methods influence fiber formation and performance

• recent years, electrospinning has attracted significant attention from scientists because of its easy process [1]. Electrospinning can fabricate polymeric fibers ranging from the micro- to the nanoscale [2]. It is an easy, simple, and low-cost technique that does not require heat, an important factor for

• [9]. In this review, we focus on the background of the electrospinning process, the properties of chitosan/PVA electrospun nanofibers, and fabrication techniques, including the effects of various parameters and post-treatment methods. We also review the characterization of chitosan/PVA electrospun

Electrospun nanofibers: building blocks for the repair of bone tissue

• Tuğrul Mert Serim,
• Gülin Amasya,
• Tuğba Eren-Böncü,
• Ceyda Tuba Şengel-Türk and
• Ayşe Nurten Özdemir

Beilstein J. Nanotechnol. 2024, 15, 941–953, doi:10.3762/bjnano.15.77

• . Electrospinning is an easy and fast method to produce non-woven structures consisting of continuous ultrafine fibers with diameters ranging from micrometers down to nanometers. The simplicity and cost-effectiveness of the electrospinning technique, its ability to use a wide variety of synthetic, natural, and

• research and patents in the field. Keywords: bone regeneration; controlled release; drug delivery; electrospinning; nanofibers; Introduction The nanofiber technology is a recent technology developed for producing implantable systems that can be used for structural support to the bones as well as drug

• the literature including inter-surface polymerization, phase separation, drawing, self-assembly, melt blowing, template melt extrusion, forcespinning, and electrospinning [36][37][38][39][40]. Only electrospinning will be further explained in detail in order to remain within the scope. Electrospinning

Electrospun polysuccinimide scaffolds containing different salts as potential wound dressing material

• Veronika Pálos,
• Krisztina S. Nagy,
• Rita Pázmány,
• Krisztina Juriga-Tóth,
• Bálint Budavári,
• Judit Domokos,
• Dóra Szabó,
• Ákos Zsembery and
• Angela Jedlovszky-Hajdu

Beilstein J. Nanotechnol. 2024, 15, 781–796, doi:10.3762/bjnano.15.65

• of Medical Microbiology, Semmelweis University, Nagyvárad tér 4, 1089, Budapest, Hungary Department of Oral Biology, Semmelweis University, Nagyvárad tér 4, 1089, Budapest, Hungary 10.3762/bjnano.15.65 Abstract In this research, we applied electrospinning to create a two-component biodegradable

• potential cytotoxicity of the scaffolds on human tumorous and healthy cells. Except for the ones containing zinc acetate salt, the scaffolds are not cytotoxic to either tumor or healthy cells. Keywords: antibacterial activity; electrospinning; polysuccinimide; scaffold; wound dressing; Introduction

• fulfill multiple needs: shielding the wound against bacterial infection, facilitating proper gas exchange, providing an environment that promotes healing, and controlling biofluid production [8][9]. Furthermore, it should be nontoxic and hypoallergenic [10]. By using electrospinning, nanofibers can be

Study of the reusability and stability of nylon nanofibres as an antibody immobilisation surface

• Inés Peraile,
• Matilde Gil-García,
• Laura González-López,
• Nushin A. Dabbagh-Escalante,
• Juan C. Cabria-Ramos and
• Paloma Lorenzo-Lozano

Beilstein J. Nanotechnol. 2024, 15, 83–94, doi:10.3762/bjnano.15.8

• electrospinning have been carried out in our laboratory, determining the optimal nanofibre thickness regarding stability and biofunctionalisation [16]. Our results showed that the NFs’ surface provides advantages over a planar nylon surface in terms of increased immunocapture efficiency as the higher surface area

• , because the NFs protects the immunocapture system better than a planar surface specialised for anchoring antibodies, they allow the immunocapture system to extend its shelf life. Experimental Chemicals PA6 was made by electrospinning by Tecnalia Research & Innovation, the composition of the ultrathin NFs

Berberine-loaded polylactic acid nanofiber scaffold as a drug delivery system: The relationship between chemical characteristics, drug-release behavior, and antibacterial efficiency

• Le Thi Le,
• Hue Thi Nguyen,
• Liem Thanh Nguyen,
• Huy Quang Tran and
• Thuy Thi Thu Nguyen

Beilstein J. Nanotechnol. 2024, 15, 71–82, doi:10.3762/bjnano.15.7

• prepared by antisolvent precipitation could reach up to 5.0 mg/mL, which notably increased the antibacterial activity of BBR [7]. Electrospinning is a convenient technique that allows one to fabricate nanofiber scaffolds with various compositions and structures. During the electrospinning process, a

• polymer solution blended with additional components is applied under a high-voltage electrostatic field, generating a charged and stretched solution jet following nanofiber formation [8][9]. Drug delivery systems based on nanofiber scaffolds produced by electrospinning method have strongly attracted

• separation during the electrospinning process [17][38][39], leading to the formation of a BBR-rich phase on the surface of nanofibers. The crystallinity of the PLA pellet and electrospun nanofiber scaffolds were examined by X-ray diffraction (XRD) analysis (Figure 3B). The XRD pattern of the PLA pellet shows

Hierarchically patterned polyurethane microgrooves featuring nanopillars or nanoholes for neurite elongation and alignment

• Lester Uy Vinzons,
• Guo-Chung Dong and
• Shu-Ping Lin

Beilstein J. Nanotechnol. 2023, 14, 1157–1168, doi:10.3762/bjnano.14.96

• fabrication. For instance, traditional techniques, such as electron-beam lithography, laser writing, and cleanroom photolithography, have flexibility in design but require costly equipment [13][14]. Relatively cheaper techniques, such as anodization, electroplating, and electrospinning, are limited by the

A wearable nanoscale heart sound sensor based on P(VDF-TrFE)/ZnO/GR and its application in cardiac disease detection

• Yi Luo,
• Jian Liu,
• Jiachang Zhang,
• Yu Xiao,
• Ying Wu and
• Zhidong Zhao

Beilstein J. Nanotechnol. 2023, 14, 819–833, doi:10.3762/bjnano.14.67

• University, Hangzhou 310018, China School of Cyberspace Security, Hangzhou DIANZI University, Hangzhou 310018, China 10.3762/bjnano.14.67 Abstract This paper describes a method for preparing flexible composite piezoelectric nanofilms of P(VDF-TrFE)/ZnO/graphene using a high-voltage electrospinning method

• system designed in this paper can collect heart sound signals in real time and predict whether the heart sounds are normal or abnormal, providing a new solution for the diagnosis of heart diseases. Keywords: composite piezoelectric nanofilm; electrospinning; heart sound classification algorithm; heart

• improved the film-making process by adding fillers to P(VDF-TrFE), using secondary polarization, and applying other methods to enhance its piezoelectric performance. Kumar et al. prepared P(VDF-TrFE)/ZnO matrix composite nanogenerators using electrospinning. Voltage and current of these nanogenerators were

Bismuth-based nanostructured photocatalysts for the remediation of antibiotics and organic dyes

• Akeem Adeyemi Oladipo and
• Faisal Suleiman Mustafa

Beilstein J. Nanotechnol. 2023, 14, 291–321, doi:10.3762/bjnano.14.26

• . The final product might have some impurities, relatively large particles, and only a small degree of homogeneity. Large volumes of nanopowder can be produced using a relatively simple apparatus via solid-state routes. Wet-chemical methods (such as electrospinning, sol–gel, hydrothermal, ultrasound, co

Batch preparation of nanofibers containing nanoparticles by an electrospinning device with multiple air inlets

• Dong Wei,
• Chengwei Ye,
• Adnan Ahmed and
• Lan Xu

Beilstein J. Nanotechnol. 2023, 14, 141–150, doi:10.3762/bjnano.14.15

• has become a research hotspot. As the distribution uniformity of nanoparticles in functional nanofibers has a great impact on their performance, an electrospinning device with multiple air inlets, which has a copper porous spinneret, is proposed to obtain functional nanofibers with higher yield and

• were higher than those prepared by other high-yield electrospinning devices. Keywords: batch preparation; electric field simulation; electrospinning device; functional nanofibers; nanoparticles; Introduction In recent years, due to the characteristics of high specific surface area, good electrical

• conductivity, stable physical and chemical properties, as well as fast charge and discharge, the application of electrospun nanofiber-based materials in supercapacitor electrode materials has attracted great attention [1][2]. Although traditional single-needle electrospinning (SNE) devices are widely used and

Recent trends in Bi-based nanomaterials: challenges, fabrication, enhancement techniques, and environmental applications

• Vishal Dutta,
• Ankush Chauhan,
• Ritesh Verma,
• C. Gopalkrishnan and
• Van-Huy Nguyen

Beilstein J. Nanotechnol. 2022, 13, 1316–1336, doi:10.3762/bjnano.13.109

• of one semiconductor to the VB of the other in an S-scheme heterojunction photocatalyst due to an IEF that typically exists at the interface of the two semiconductors [104]. Lately, Xu et al. reported the fabrication of a MoS2/BiVO4 heterojunction via solvothermal and electrospinning techniques [105

Laser-processed antiadhesive bionic combs for handling nanofibers inspired by nanostructures on the legs of cribellate spiders

• Sebastian Lifka,
• Kristóf Harsányi,
• Erich Baumgartner,
• Lukas Pichler,
• Dariya Baiko,
• Karsten Wasmuth,
• Johannes Heitz,
• Marco Meyer,
• Anna-Christin Joel,
• Jörn Bonse and
• Werner Baumgartner

Beilstein J. Nanotechnol. 2022, 13, 1268–1283, doi:10.3762/bjnano.13.105

• randomly rough surfaces. The latter revealed that the adhesion of electrospun nanofiber nonwoven is significantly lowered on the nanostructured surfaces compared with the polished surfaces. Keywords: biomimetics; electrospinning; laser-induced periodic surface structures (LIPSS); nanofibers

• as electrospinning [1][2][6][7][8] or microfluidic spinning [4] have been established. Despite a lot of effort to facilitate the production and handling of nanofibers [3][4][5][6][7], the stickiness of freshly produced and, thus, fragile nanofiber nonwoven mats remains a problem. This is mainly

• fibers In order to test the theory derived above, electrospinning of polyamide 6 (PA-6) in a laboratory setup onto structured metal samples (aluminum alloy, steel, and titanium alloy) was performed and the peel-off forces were determined using a custom-made peel-test device. PA-6 has an elastic modulus E

Application of nanoarchitectonics in moist-electric generation

• Jia-Cheng Feng and
• Hong Xia

Beilstein J. Nanotechnol. 2022, 13, 1185–1200, doi:10.3762/bjnano.13.99

• Harvest from Moist Air Flow”, Adv. Funct. Mater., with permission from John Wiley and Sons. Copyright © 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This content is not subject to CC BY 4.0. (h) Schematic diagram of the electrospinning apparatus and (i) large-area, flexible, and deformable nanofiber

Biomimetic chitosan with biocomposite nanomaterials for bone tissue repair and regeneration

• Se-Kwon Kim,
• Sesha Subramanian Murugan,
• Pandurang Appana Dalavi,
• Sebanti Gupta,
• Sukumaran Anil,
• Gi Hun Seong and
• Jayachandran Venkatesan

Beilstein J. Nanotechnol. 2022, 13, 1051–1067, doi:10.3762/bjnano.13.92

• osteoblasts [63]. In another study, Li et al. (2015) used the electrospinning method to fabricate chitosan and MSN-containing nanofibers. In addition, an increase in mechanical strength was observed with an increase in the MSN content. Further in vitro assays reveal that nanofibres slowly degrade and have a

• adhesion and migration of mesenchymal stem cells confirmed by cell adhesion and morphology studies. The cell differentiation activity of 3D-printed scaffolds was confirmed by the alkaline phosphatase activity assay on the 14th day [127]. Liu et al. (2020) has used 3D printing and electrospinning for the

• fabrication of scaffolds for cartilage tissue engineering applications. The 2 cm × 2 cm PLGA electrospun nanofibers were prepared by electrospinning which incorporated those with hydroxybutyl chitosan hydrogels. The polycaprolactone scaffold was 3D printed and reinforced with hydrogel scaffolds to mimic the

Micro- and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritis

• Zahra Nabizadeh,
• Mahmoud Nasrollahzadeh,
• Hamed Daemi,
• Mohamadreza Baghaban Eslaminejad,
• Ali Akbar Shabani,
• Mehdi Dadashpour,
• Majid Mirmohammadkhani and
• Davood Nasrabadi

Beilstein J. Nanotechnol. 2022, 13, 363–389, doi:10.3762/bjnano.13.31

• different characteristics and kinds of behavior of compounds on submicrometer and nanometer scales and resulted in the development of new methods such as electrospinning, self-assembly, phase separation, nano-imprinting, and photolithography for the generation of new biomaterials with improved properties

• nature. They are constructed as NPs, nanofibers, nanocrystals, nanotubes, and nanofilms by high-tech methods of photolithography, electrospinning, nanoimprinting, and phase separation. Due to the hierarchical structure of articular cartilage ECM, there is considerable enthusiasm regarding the use of

• , electrospinning, weaving, phase separation, and template synthesis [102]. Electrospinning is widely used given its simplicity, cost effectiveness, unlimited substrate use, appreciable surface to volume ratio, tunable porosity, and ability to generate nanofibers over a wide range of sizes and shapes [102

Effects of drug concentration and PLGA addition on the properties of electrospun ampicillin trihydrate-loaded PLA nanofibers

• Tuğba Eren Böncü and
• Nurten Ozdemir

Beilstein J. Nanotechnol. 2022, 13, 245–254, doi:10.3762/bjnano.13.19

• produce ampicillin trihydrate-loaded poly(lactic acid) (PLA) and PLA/poly(lactic-co-glycolic acid) (PLA/PLGA) polymeric nanofibers via electrospinning using 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) as the solvent for local application in tissue engineering. The effects of ampicillin trihydrate

• desired properties (average nanofiber diameter, morphology, in vitro drug release, and mechanical properties) of PLA nanofibers. Keywords: ampicillin trihydrate; electrospinning; nanofiber; PLA nanofiber; PLA/PLGA nanofiber; Introduction Polymeric nanofibers have been widely used in many fields such as

• tissue engineering and drug delivery systems. Electrospinning is the most commonly used polymeric nanofiber preparation method, because it is an easy, single-step, low-cost, and reproducible method. It allows for the production of extracellular matrix-like nanofibers that can be easily scaled up and has

Engineered titania nanomaterials in advanced clinical applications

• Padmavati Sahare,
• Paulina Govea Alvarez,
• Juan Manual Sanchez Yanez,
• Gabriel Luna-Bárcenas,
• Samik Chakraborty,
• Sujay Paul and
• Miriam Estevez

Beilstein J. Nanotechnol. 2022, 13, 201–218, doi:10.3762/bjnano.13.15

• standard glass surface [82]. Another recent study stated that hollow, calcined TiO2 nanospheres (CSTiO2), synthesized by the combination of electrospinning and atomic layer deposition, have high antimicrobial activity against multidrug-resistant bacteria such as S. aureus strains compared to commercial

Piezoelectric nanogenerator for bio-mechanical strain measurement

• Zafar Javed,
• Lybah Rafiq,
• Muhammad Anwaar Nazeer,
• Saqib Siddiqui,
• Muhammad Babar Ramzan,
• Muhammad Qamar Khan and
• Muhammad Salman Naeem

Beilstein J. Nanotechnol. 2022, 13, 192–200, doi:10.3762/bjnano.13.14

• . Keywords: electrospinning; human body angle measurement; nanofibers; piezoelectric; PVDF; Introduction Smart textiles are normally elevated to value-added textile products with improved properties and characteristics [1]. They exhibit properties of a textile with some added characteristics. Smart textiles

• electrospinning. A conventional electrospinning process was used to create the piezoelectric electrospun nanofibers. The polymeric solution was pumped from a metallic syringe needle of 0.4 mm inner diameter at a flow rate of 3.5 mL/h. The fibers were collected on a stationary collector placed at a working

A comprehensive review on electrospun nanohybrid membranes for wastewater treatment

• Senuri Kumarage,
• Imalka Munaweera and
• Nilwala Kottegoda

Beilstein J. Nanotechnol. 2022, 13, 137–159, doi:10.3762/bjnano.13.10

• for Advanced Materials Research (CAMR), Faculty of Applied Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka 10.3762/bjnano.13.10 Abstract Electrospinning, being a versatile and straightforward method to produce nanofiber membranes, has shown significant advancement in

• discussed. Finally, an outlook on the future research pathways to fill the gaps existing in water remediation have been suggested. Keywords: electrospinning; environmental remediation; membrane technologies; nanohybrids; water purification; Review 1 Introduction Nanotechnology is a technique that exploits

• , and phase inversion [1] to fabricate porous nanomembranes, electrospinning is a straightforward emerging technology that uses electrostatic forces to produce ultrathin fibers with diameters at the nanometer scale. In comparison to the membranes developed via other methodologies, electrospinning

The effect of cobalt on morphology, structure, and ORR activity of electrospun carbon fibre mats in aqueous alkaline environments

• Markus Gehring,
• Tobias Kutsch,
• Osmane Camara,
• Alexandre Merlen,
• Hermann Tempel,
• Hans Kungl and
• Rüdiger-A. Eichel

Beilstein J. Nanotechnol. 2021, 12, 1173–1186, doi:10.3762/bjnano.12.87

• at an overpotential of 100 mV and low overpotentials at current densities of 333 μA·cm−2 were found for all electrodes made from cobalt-decorated fibre mats carbonised at temperatures between 800 and 1000 °C. Keywords: carbon fibres; cobalt-decorated fibres; electrospinning; metal–air batteries

• three main groups: electroplating, electroless plating, and bottom-up methods such as vapour deposition. Another way to introduce metals to a carbon fibre system in form of nanoparticles was reported by groups who prepared cobalt/cobalt oxide-decorated carbon nanofibres from electrospinning by adding a

• electrospinning are a convenient and promising material for air electrodes in metal–air batteries. These studies used the cobalt-enhanced fibre material either as a bottom-up catalyst material in aqueous alkaline systems [21][22] or as free-standing electrodes in non-aqueous systems with a lab-scale geometric

Solution combustion synthesis of a nanometer-scale Co₃O₄ anode material for Li-ion batteries

• Monika Michalska,
• Huajun Xu,
• Qingmin Shan,
• Shiqiang Zhang,
• Yohan Dall'Agnese,
• Yu Gao,
• Amrita Jain and
• Marcin Krajewski

Beilstein J. Nanotechnol. 2021, 12, 424–431, doi:10.3762/bjnano.12.34

• been proposed including sol–gel methods [4][6][13][14][15], sol–electrospinning techniques [16][17][18][19], hydrothermal and solvothermal syntheses [20][21][22][23][24][25][26][27][28], precipitation and co-precipitation [29][30][31], chemical thermal decomposition and pyrolysis [32][33][34][35][36

Bulk chemical composition contrast from attractive forces in AFM force spectroscopy

• Dorothee Silbernagl,
• Media Ghasem Zadeh Khorasani,
• Natalia Cano Murillo,
• Anna Maria Elert and
• Heinz Sturm

Beilstein J. Nanotechnol. 2021, 12, 58–71, doi:10.3762/bjnano.12.5

• surface was modified with taurine (coverage of ≈16%) which was found to enable the subsequent electrospinning process. The nanoparticles were mixed in a solution of methylene chloride (CH2Cl2) and PC. The solution was electrospun to form fibers at 30 kV and at distance of 10 cm from the collector. The

Piezoelectric sensor based on graphene-doped PVDF nanofibers for sign language translation

• Shuai Yang,
• Xiaojing Cui,
• Rui Guo,
• Zhiyi Zhang,
• Shengbo Sang and
• Hulin Zhang

Beilstein J. Nanotechnol. 2020, 11, 1655–1662, doi:10.3762/bjnano.11.148

• PVDF nanofibers. The fiber properties after electrospinning were measured, and a potential application of the PES in the translation of sign language was successfully demonstrated. The designed PES shows a high sensitivity regarding both pressure and bending. In particular, a stable angle mapping under

• concentrated in the bent part of the material, and the potential is generated on the opposite side of the device. Electrospinning is used to manufacture GR-doped PVDF fibers. The overall process is shown in Figure 2a. Firstly, GR is dispersed in dimethylformamide (DMF). After ultrasonic treatment, PVDF powder

• is added under stirring to yield the spinning solution for electrospinning. After preparation of the fibers, an aqueous solution of Ti3C2 MXene and Ag NWs is sprayed on both sides of the material and then dried. Finally, the nanowire membrane is covered on both sides with PDMS to obtain the

High-responsivity hybrid α-Ag₂S/Si photodetector prepared by pulsed laser ablation in liquid

• Raid A. Ismail,
• Hanan A. Rawdhan and
• Duha S. Ahmed

Beilstein J. Nanotechnol. 2020, 11, 1596–1607, doi:10.3762/bjnano.11.142

• hydrothermal methods, chemical bath deposition, laser ablation in liquid reverse microemulsion, electrospinning, sol–gel, electrochemical method, template method, sonochemical method, and hydrochemical bath deposition [10][11][12][13]. The size of Ag2S NPs depends on the preparation conditions [14]. Ag2S NPs

Antimicrobial metal-based nanoparticles: a review on their synthesis, types and antimicrobial action

• Matías Guerrero Correa,
• Fernanda B. Martínez,
• Cristian Patiño Vidal,
• Camilo Streitt,
• Juan Escrig and
• Carol Lopez de Dicastillo

Beilstein J. Nanotechnol. 2020, 11, 1450–1469, doi:10.3762/bjnano.11.129

• , Lopez de Dicastillo et al. (2018, 2019) have recently developed hollow titanium dioxide nanotubes and nanospheres through the deposition of tetrakis(dimethylamide) titanium and water, as precursors, on polymeric structures obtained via electrospinning. The resulting hollow nanotubes and nanospheres had

• NPs has been directed towards water disinfection, food packaging in addition to their known use as a UV filter to prevent skin cancer [114]. Lopez de Dicastillo et al. (2019) developed hollow TiO2 nanotubes and nanospheres with high antimicrobial activity through the combination of electrospinning and

Structure and electrochemical performance of electrospun-ordered porous carbon/graphene composite nanofibers

• Yi Wang,
• Yanhua Song,
• Chengwei Ye and
• Lan Xu

Beilstein J. Nanotechnol. 2020, 11, 1280–1290, doi:10.3762/bjnano.11.112

• configurations were used as a material to fabricate supercapacitor electrodes. These nanofibers were synthesized by applying a modified parallel electrode to the electrospinning method (MPEM) in order to generate electrospun polyacrylonitrile (PAN) nanofibers containing graphene. After synthesis, these fibers

• ; electrochemistry; electrode material; electrospinning method; ordered and porous nanofibers; supercapacitor; Introduction As the technology sector develops, societal demands for energy storage devices also increases. Supercapacitors, including electric double-layer capacitors (EDLCs) and pseudo-capacitance

• improvement of the current supercapacitor electrochemical performance, the capacitance and cycle stability of supercapacitors are still subjects of research interest. Electrospinning is one of the most convenient methods to synthesize nanofibers in a continuous manner. Electrospinning has many advantages over