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Search for "engulfment" in Full Text gives 6 result(s) in Beilstein Journal of Nanotechnology.
Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy
Beilstein J. Nanotechnol. 2025, 16, 97–118, doi:10.3762/bjnano.16.10
- saturation of the uptake with other non-toxic NPs administered as a pre-treatment. The disruption of lysosome and endocytotic processes causes the engulfment of KCs and the temporary blockade of the MPS. Although the induced modulation of innate immunity is effective, these strategies may lead to an
Dual-functionalized architecture enables stable and tumor cell-specific SiO2NPs in complex biological fluids
Beilstein J. Nanotechnol. 2024, 15, 1238–1252, doi:10.3762/bjnano.15.100
- -1-antiproteinase) are called opsonins, so when present in high amounts in the protein corona they will induce macrophage recognition and engulfment of NPs, leading to the fast removal of NPs out of the body [43][45]. Finally, it should be noted that alpha and beta hemoglobins, classified in the
pH-driven enhancement of anti-tubercular drug loading on iron oxide nanoparticles for drug delivery in macrophages
Beilstein J. Nanotechnol. 2021, 12, 1127–1139, doi:10.3762/bjnano.12.84
- identical treatment conditions (Figure 6a). The increased uptake could be due to active engulfment of nanoparticles by macrophages, due to their larger size (20–120 nm size range) and surface charge (+29 mV or −16.5 mV) [46], which results in simultaneous internalization of larger amounts of drug. Figure 6b
On the pathway of cellular uptake: new insight into the interaction between the cell membrane and very small nanoparticles
Beilstein J. Nanotechnol. 2016, 7, 1296–1311, doi:10.3762/bjnano.7.121
- suspension was added to the cell culture medium, yielding the final concentration for exposure. For transmission electron microscopy and for cytotoxicity assays, cells were incubated with SiNPs for 10 min to 24 h at 37 °C and 5% CO2 before further processing. To check if the observed particle engulfment is
Silica-coated upconversion lanthanide nanoparticles: The effect of crystal design on morphology, structure and optical properties
Beilstein J. Nanotechnol. 2015, 6, 2290–2299, doi:10.3762/bjnano.6.235
- specific application. Thus, various ligands and functionalities have to be attached to the particle surface to provide efficient drug delivery, to ensure engulfment by the cells, or to control the release of biomolecules and their specific target. Finally, the surface modification must ensure that the
Intake of silica nanoparticles by giant lipid vesicles: influence of particle size and thermodynamic membrane state
Beilstein J. Nanotechnol. 2014, 5, 2468–2478, doi:10.3762/bjnano.5.256
- of nanoparticles into cells often involves their engulfment by the plasma membrane and a fission of the latter. Understanding the physical mechanisms underlying these uptake processes may be achieved by the investigation of simple model systems that can be compared to theoretical models. Here, we
- models and indicate that these models have to be extended in order to capture the interaction between nanomaterials and biological membranes correctly. Keywords: cells; endocytosis; engulfment; fission; gel phase; giant unilamellar lipid vesicles (GUV); lipid membranes; liquid phase; nanoparticle
- . Especially the dependence of the uptake efficiency on the particle size is still an important topic [11][12]. Usually, a complex cell machinery is involved in endocytosis. However, particle uptake including the engulfment by the membrane has also been reported for red blood cells, which are known for not
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