Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

• Shakhzodjon Uzokboev,
• Khojimukhammad Akhmadbekov,
• Ra’no Nuritdinova,
• Salah M. Tawfik and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

• [126]. The biosensing capabilities of alginate-based nanoparticles have been established by several studies. For example, glucose oxidase encapsulated in an alginate biopolymer can detect glucose levels in human blood samples with excellent precision and sensitivity. Similarly, scientists created an

• alginate–CuO–glucose oxidase-based biosensor for glucose detection, which demonstrated high repeatability and long-term stability. Another research used horseradish peroxidase coated in calcium alginate beads to detect hydrogen peroxide in ambient water samples [127]. Ionotropic alginate hydrogel

• meet the specific needs of glucose detection, such as incorporating glucose oxidase for enzymatic sensing, allowing for efficient and accurate glucose detection [140]. The fabrication of alginate-based nanoparticles for glucose detection involves several steps. First, alginate is mixed with a cross

Classification and application of metal-based nanoantioxidants in medicine and healthcare

• Nguyen Nhat Nam,
• Nguyen Khoi Song Tran,
• Tan Tai Nguyen,
• Nguyen Ngoc Trai,
• Nguyen Phuong Thuy,
• Hoang Dang Khoa Do,
• Nhu Hoa Thi Tran and
• Kieu The Loan Trinh

Beilstein J. Nanotechnol. 2024, 15, 396–415, doi:10.3762/bjnano.15.36

• -, peroxidase (POD)-, glucose oxidase (GOx)-, and nitric oxide synthase (NOS)-like activities. More interestingly, both in vitro and in vivo experiments demonstrated that the nanocomposite spray can be activated by the diabetic foot ulcer microenvironment to accelerate diabetic wound healing through decreasing

Carboxylic acids and light interact to affect nanoceria stability and dissolution in acidic aqueous environments

• Matthew L. Hancock,
• Eric A. Grulke and
• Robert A. Yokel

Beilstein J. Nanotechnol. 2023, 14, 762–780, doi:10.3762/bjnano.14.63

• glucose oxidase, suggesting the use of this phenomenon as a colorimetric sensor for bioanalysis [49]. This color transition is an important observation since nanoceria degradation will likely result in the change in oxidation state of surface cerium ions from Ce4+ to Ce3+. Results and Discussion Nanoceria

Interaction between honeybee mandibles and propolis

• Leonie Saccardi,
• Franz Brümmer,
• Jonas Schiebl,
• Oliver Schwarz,
• Alexander Kovalev and
• Stanislav Gorb

Beilstein J. Nanotechnol. 2022, 13, 958–974, doi:10.3762/bjnano.13.84

• that due to gland development, only older stingless bees are able to handle propolis [20]. Mandibular glands of honeybees have been found to have a high potential to produce lipids [41]. Glucose oxidase, produced in the mandibular glands, has been found in propolis [42][43]. Which could be an indicator

Nanogenerator-based self-powered sensors for data collection

• Yicheng Shao,
• Maoliang Shen,
• Yuankai Zhou,
• Xin Cui,
• Lijie Li and
• Yan Zhang

Beilstein J. Nanotechnol. 2021, 12, 680–693, doi:10.3762/bjnano.12.54

• direction of future medicine. Zhang et al. [31] developed a self-powered implantable blood glucose meter based on the piezo-enzymatic-reaction coupling effect of GOx@ZnO (GOx: glucose oxidase) nanowires. By collecting the mechanical energy generated by human movement, the output voltage provided information

Multilayer capsules made of weak polyelectrolytes: a review on the preparation, functionalization and applications in drug delivery

• Varsha Sharma and
• Anandhakumar Sundaramurthy

Beilstein J. Nanotechnol. 2020, 11, 508–532, doi:10.3762/bjnano.11.41

Poly(1-vinylimidazole) polyplexes as novel therapeutic gene carriers for lung cancer therapy

• Gayathri Kandasamy,
• Elena N. Danilovtseva,
• Vadim V. Annenkov and
• Uma Maheswari Krishnan

Beilstein J. Nanotechnol. 2020, 11, 354–369, doi:10.3762/bjnano.11.26

• and the enzyme glucose oxidase for glucose-sensing applications [11]. A hydrogel of xanthan gum and poly(1-vinylimidazole) was recently explored for protein encapsulation and delivery. The system exerted no toxic effects on cells and maintained the functionality of the protein [12]. A pyrrole

Molecular architectonics of DNA for functional nanoarchitectures

• Debasis Ghosh,
• Lakshmi P. Datta and
• Thimmaiah Govindaraju

Beilstein J. Nanotechnol. 2020, 11, 124–140, doi:10.3762/bjnano.11.11

• scaffold embedded with Ru(bpy)32+-conjugated silica nanoparticles. The DNA tetrahedron geometry acted as a capture DNA that repelled the nonspecific DNA entanglement along the ECL platform and stimulated the hybridization of glucose oxidase (GOD) enzyme-conjugated DNA (GOD-S). In a programmable cyclic

Use of data processing for rapid detection of the prostate-specific antigen biomarker using immunomagnetic sandwich-type sensors

• Camila A. Proença,
• Tayane A. Freitas,
• Thaísa A. Baldo,
• Elsa M. Materón,
• Flávio M. Shimizu,
• Gabriella R. Ferreira,
• Frederico L. F. Soares,
• Ronaldo C. Faria and
• Osvaldo N. Oliveira Jr.

Beilstein J. Nanotechnol. 2019, 10, 2171–2181, doi:10.3762/bjnano.10.210

• Prussian blue (PB) interlayer and a gold shell. The enzymes horseradish peroxidase and glucose oxidase were immobilized to improve sensitivity, with linear ranges between 0.01 and 80.0 ng·mL−1 for CEA and from 0.014 to 142 ng·mL−1 for AFP, and detection limits of 4 pg·mL−1 and 7 pg·mL−1, respectively [25

Materials nanoarchitectonics at two-dimensional liquid interfaces

• Katsuhiko Ariga,
• Michio Matsumoto,
• Taizo Mori and
• Lok Kumar Shrestha

Beilstein J. Nanotechnol. 2019, 10, 1559–1587, doi:10.3762/bjnano.10.153

Multicomponent bionanocomposites based on clay nanoarchitectures for electrochemical devices

• Giulia Lo Dico,
• Bernd Wicklein,
• Lorenzo Lisuzzo,
• Giuseppe Lazzara,
• Pilar Aranda and
• Eduardo Ruiz-Hitzky

Beilstein J. Nanotechnol. 2019, 10, 1303–1315, doi:10.3762/bjnano.10.129

• glucose oxidase (GOx) into the lumen of HNTs has been chosen here as an example for the immobilization of bioactive species, which can be crucial to design (bio)electrochemical devices with high performance and long life-time. The SEP, GNP, and MWCNT components are also expected to behave as polymer

• material in aqueous media. Moreover, the successful incorporation of HNTs as nanoreactor prompted the use of these bionanocomposite materials in bioelectrocatalysis applications (see below). Immobilization of glucose oxidase in the lumen of HNTs The developed multicomponent bionanocomposites were used for

• the immobilization of the enzyme glucose oxidase in the search of multifunctional properties of interest in bioelectrochemical applications. GOx was chosen as a prototypic bioactive component because of its properties and compatibility with HNTs, i.e., an appropriate size (5.4 nm) as well as an

Characterization of ferrite nanoparticles for preparation of biocomposites

• Urszula Klekotka,
• Magdalena Rogowska,
• Dariusz Satuła and
• Beata Kalska-Szostko

Beilstein J. Nanotechnol. 2017, 8, 1257–1265, doi:10.3762/bjnano.8.127

• with a bioparticle was studied. In subsequent steps, the nanoparticles were immobilized with enzymes such as albumin, glucose oxidase, lipase and trypsin as a test bioparticles. The characterization of the nanoparticles was acheived by transmission electron microscopy, X-ray diffraction, energy

• dispersive X-ray and Mössbauer spectroscopy. The effect of the obtained biocomposites was monitored by Fourier transform infrared spectroscopy. The obtained results show that in some cases the use of glutaraldehyde was crucial (albumin). Keywords: albumin; EDX; glucose oxidase; IR spectroscopy; lipase

• , we have used nanoparticles with or without attached glutaraldehyde that served as a linker between the nanoparticle and enzymes and gives more space for interaction. The enzymes tested in this paper were: albumin, glucose oxidase, lipase, and trypsin. This study is a continuation of our previous

Novel roles for well-known players: from tobacco mosaic virus pests to enzymatically active assemblies

• Claudia Koch,
• Fabian J. Eber,
• Carlos Azucena,
• Alexander Förste,
• Stefan Walheim,
• Thomas Schimmel,
• Alexander M. Bittner,
• Holger Jeske,
• Hartmut Gliemann,
• Sabine Eiben,
• Fania C. Geiger and
• Christina Wege

Beilstein J. Nanotechnol. 2016, 7, 613–629, doi:10.3762/bjnano.7.54

• and ZYMV particles. Since diagnostic assays could profit particularly from novel nanosculptured high-density presentation platforms, a glucose-sensing enzyme combination of glucose oxidase (GOx) and signal-generating horseradish peroxidase (HRP) was applied (see below in Figure 5 and Figure 6). Due to

Optimized design of a nanostructured SPCE-based multipurpose biosensing platform formed by ferrocene-tethered electrochemically-deposited cauliflower-shaped gold nanoparticles

• Wicem Argoubi,
• Maroua Saadaoui,
• Sami Ben Aoun and
• Noureddine Raouafi

Beilstein J. Nanotechnol. 2015, 6, 1840–1852, doi:10.3762/bjnano.6.187

• through a ethylenediamine spacer was prepared by Fan et al. and used as an efficient electron transfer (ET) shuttle to build a sensor for H2O2 [16]. Also, a nanocomposite formed with ferrocene-branched silica material reduced graphene oxide and glucose oxidase entrapped in chitosan matrix and was used for

Protein-coated pH-responsive gold nanoparticles: Microwave-assisted synthesis and surface charge-dependent anticancer activity

• Dickson Joseph,
• Nisha Tyagi,
• Christian Geckeler and
• Kurt E.Geckeler

Beilstein J. Nanotechnol. 2014, 5, 1452–1462, doi:10.3762/bjnano.5.158

• observed after the reaction for all of the proteins except trypsin (TRY) and glucose oxidase (GOX). The AuNPs formed in the presence of the different proteins were characterized by UV–vis spectroscopy (Figure 1). The addition of Ag ions played an important role in the formation of the AuNPs, which is

• histone (HIS), chicken egg white lysozyme (LYS), ovalbumin (OVA), bovine serum albumin (BSA), bovine hemoglobin (BHG), bovine gamma globulin (BGG), glucose oxidase (Aspergillus niger) (GOX), and trypsin (porcine pancreas, TRY), used for the experiments were obtained from Sigma (USA) as a lyophilized

Functionalization of vertically aligned carbon nanotubes

• Eloise Van Hooijdonk,
• Carla Bittencourt,
• Rony Snyders and
• Jean-François Colomer

Beilstein J. Nanotechnol. 2013, 4, 129–152, doi:10.3762/bjnano.4.14