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Search for "nanoemulsion" in Full Text gives 8 result(s) in Beilstein Journal of Nanotechnology.
Nanotechnological approaches for efficient N2B delivery: from small-molecule drugs to biopharmaceuticals
Beilstein J. Nanotechnol. 2024, 15, 1400–1414, doi:10.3762/bjnano.15.113
- nanoemulsion formulation with a particle size of 91.20 nm increased the drug absorption into the brain via the intranasal route compared to the mucoadhesive suspension form [115]. The encapsulation of a poorly soluble drug, cannabidiol, into nanoemulsions for the treatment of epilepsy was also evaluated. The
Therapeutic effect of F127-folate@PLGA/CHL/IR780 nanoparticles on folate receptor-expressing cancer cells
Beilstein J. Nanotechnol. 2024, 15, 954–964, doi:10.3762/bjnano.15.78
- pluronic F127 (F127), can be used in the water phase to lower the surface tension of the organic phase and to produce the nanoemulsion during the homogenization process [5][6][7]. F127 is a copolymer made up of blocks of poly(ethylene oxide)–poly(propylene oxide)–poly(ethylene oxide), PEO100–PPO65–PEO100
Development and characterization of potential larvicidal nanoemulsions against Aedes aegypti
Beilstein J. Nanotechnol. 2024, 15, 104–114, doi:10.3762/bjnano.15.10
- involving Galleria mellonella larvae. Additionally, we investigated the insecticidal efficacy of monoterpenes against the mosquito Aedes aegypti, the primary dengue vector, via larval bioassay. Employing a low-energy approach, we successfully generated nanoemulsions. The cymene-based nanoemulsion exhibited
- a hydrodynamic diameter of approximately 98 nm and a zeta potential of −25 mV. The myrcene-based nanoemulsion displayed a hydrodynamic diameter of 118 nm and a zeta potential of −20 mV. Notably, both nanoemulsions demonstrated stability over 60 days, accompanied by controlled release properties and
- HLB, one can obtain the nanoemulsion with the smallest droplet size, leading to more stable formulations [20]. The rHLB is usually determined by preparing NEs with different ratios of surfactant blends and choosing the most stable formulation to determine the rHLB of the oil phase [21
Nanotechnological approaches in the treatment of schistosomiasis: an overview
Beilstein J. Nanotechnol. 2024, 15, 13–25, doi:10.3762/bjnano.15.2
- permeability through the cellular membrane by making a nanoemulsion of Curcuma longa extract (i.e., the curcumin plant source). The nanoemulsion showed an effect against adults of S. mansoni in vitro (especially males). This is an interesting finding because data from the literature reports that females are
- mechanism by which the nanoemulsion could reduce the worm burden is its antimicrobial activity, connecting changes in microbiota with the response to parasites. However, the mechanism of action of carvacrol remains unknown [67]. Repositioned drugs Works utilizing compounds repositioned from other diseases
- schistosomiasis treatment. Araújo et al. [76] developed a cationic nanoemulsion to increase solubility. This nanoemulsion increases efficiency in vitro, causing the death of female worms within three hours, alterations in tegument within 48 hours, and reduced male worm motility. A hypothesis suggested by the
Polymer nanoparticles from low-energy nanoemulsions for biomedical applications
Beilstein J. Nanotechnol. 2023, 14, 339–350, doi:10.3762/bjnano.14.29
- liquid phase. They are out-of-equilibrium nanocolloids in which phase separation is expected from thermodynamics, but is delayed by the presence of surfactants adsorbed on the droplets surface. Accordingly, nanoemulsion formation depends on the way the sample is prepared, for example, on the order of
- component addition or on the thermal history. Nanoemulsions are not to be confused with microemulsions, which are equilibrium systems with thermodynamic stability [4]. Because of their very small drop size, the main mechanism for nanoemulsion destabilization is commonly attributed to Ostwald ripening
- ] proceeds at constant temperature (Figure 1b). Here, the change in the curvature of the surfactant layer from negative to positive or vice versa is driven by the addition of water (which increases POE hydration) to a mixture of oil + surfactant to produce an O/W nanoemulsion [14]. Under continued dilution
Use of nanosystems to improve the anticancer effects of curcumin
Beilstein J. Nanotechnol. 2021, 12, 1047–1062, doi:10.3762/bjnano.12.78
- used to produce their CUR-nicotinamide nanococrystal. The nanosystem showed a higher dissolution rate, in addition to antinociceptive and anti-inflammatory effects. In contrast to their advantages, cocrystals are not easily obtained. Another option is to formulate a nanoemulsion that contains CUR as
- the molecule of interest alongside another bioactive entity (i.e., coadministration). Curcumin–piperine nanoemulsion (CUR–PIP) is a great example of this combination approach as a chemotherapy agent against various types of cancer. Piperine has been shown to act as a bioenhancer molecule that improves
- nanoemulsion (25 µM-7 µM) inhibited cell proliferation by 50% via cell cycle arrest at the G2/M phase and induced apoptosis. In addition, a CUR nanoemulsion exerted a four-fold increase in caspase-3, in contrast to a six-fold increase exerted by co-administered CUR–PIP. Curcumin is also commonly co-loaded in
Phase inversion-based nanoemulsions of medium chain triglyceride as potential drug delivery system for parenteral applications
Beilstein J. Nanotechnol. 2020, 11, 213–224, doi:10.3762/bjnano.11.16
- Kolliphor HS 15. The experimental results indicate, that nanoemulsions with particles of small and tunable size can be easily formed without homogenization by thermal cycling. Keywords: cellular toxicity; isotonicity; nanoemulsion; phase inversion; solvent free; surface properties; Introduction Nanoscaled
- incipient phase inversion from 81.5 °C at 0.4 wt % NaCl concentration to 65.4 °C at 5 wt % NaCl concentration. The particles in the nanoemulsion had an average diameter (zave) of 56–59 nm and a remarkably narrow polydispersity index (PDI) distribution of 0.03–0.06. The salinity did not have a significant
- influence on the particle diameter and the PDI of the nanoemulsion formed by shock dilution. Figure 2 shows the particle diameters and the PDIs of different nanoemulsions prepared using 1.75 wt % and 5 wt % NaCl solutions. Nanoemulsions were successfully formed using solutions of the compositions indicated
BergaCare SmartLipids: commercial lipophilic active concentrates for improved performance of dermal products
Beilstein J. Nanotechnol. 2019, 10, 2152–2162, doi:10.3762/bjnano.10.208
- cream, the melting enthalpy will decrease. Thus, the physical stability of SmartLipids is easy to analyze and to prove. Chemical stabilization of active agents Classical fluid carriers such as nanoemulsion and liposomes have a limited ability to protect labile lipophilic active agents. Due to the
- carrier systems, but only with limited increase in stability. Stabilities reported were 20% after ten days in liposomes [18], 40% after 24 h in a nanoemulsion [19], 50% after 24 h in zein colloidal particles [19] and 60% after one month in a nanoemulsion stabilized by silica [20]. A screening was
- with production capacities of up to 10.000 L/h (large scale). The obtained hot nanoemulsion is cooled, the lipid blend re-crystallizes and forms solid lipid particles. The suspensions are preserved by standard preservatives (e.g., euxyl® PE 9010) or are alternatively prepared preservative-free by
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