Radiosensitizing properties of dual-functionalized carbon nanostructures loaded with temozolomide

• Radmila Milenkovska,
• Nikola Geskovski,
• Dushko Shalabalija,
• Ljubica Mihailova,
• Petre Makreski,
• Dushko Lukarski,
• Igor Stojkovski,
• Maja Simonoska Crcarevska and
• Kristina Mladenovska

Beilstein J. Nanotechnol. 2025, 16, 229–251, doi:10.3762/bjnano.16.18

• -functionalized carbon nanostructures (CNs) were evaluated in vitro on a GBM cell line (U87MG), as well as their radiosensitizing properties after exposure of the pre-treated GBM cells to gamma radiation with a standard clinical dose for patients with GBM. All prepared formulations underwent biopharmaceutical and

• nanostructures; cytotoxicity; glioblastoma multiforme; radiosensitizing properties; temozolomide; Introduction Carbon-based nanostructures (CNs) such as graphene and its derivatives, carbon nanotubes (CNTs), fullerenes, carbon quantum dots, carbon nanohorns and nanodiamonds (NDs), and their hybrids are becoming

• enable transport and delivery to brain tumors. Inorganic nanostructures as TMZ carriers have shown several advantages compared to organic ones with respect to physicochemical stability and potency/cytotoxic activity, overcoming their main disadvantages, that is, hydrophobicity/fluidity and toxicity by

Advanced atomic force microscopy techniques V

• Philipp Rahe,
• Ilko Bald,
• Nadine Hauptmann,
• Regina Hoffmann-Vogel,
• Harry Mönig and
• Michael Reichling

Beilstein J. Nanotechnol. 2025, 16, 54–56, doi:10.3762/bjnano.16.6

• Philipp Rahe Ilko Bald Nadine Hauptmann Regina Hoffmann-Vogel Harry Monig Michael Reichling Institut für Physik, Universität Osnabrück, Barbarastraße 7, 49076 Osnabrück, Germany Institute of Chemistry, Hybrid Nanostructures, University of Potsdam, Karl-Liebknecht-Straße 24–25, 14476 Potsdam

Bioinspired nanofilament coatings for scale reduction on steel

• Siad Dahir Ali,
• Mette Heidemann Rasmussen,
• Jacopo Catalano,
• Christian Husum Frederiksen and
• Tobias Weidner

Beilstein J. Nanotechnol. 2025, 16, 25–34, doi:10.3762/bjnano.16.3

• , which employs micro- and nanostructures to repel water, we investigate the application of silicone nanofilaments (SNFs) as a coating on steel surfaces to mitigate scaling. Silicone nanofilaments, previously successful on polymers, textiles, and glass, are explored for their hydrophobic properties and

• multiscale structuring, from micron-sized hair-like structures all the way to nanometer-scale spikes and indentations can maintain the layer of air between the cuticle and water, which is needed for Collembola survival (Figure 1C,D). Inspired by the intricate nanostructures found on Collembola skin, we

Orientation-dependent photonic bandgaps in gold-dust weevil scales and their titania bioreplicates

• Norma Salvadores Farran,
• Limin Wang,
• Primoz Pirih and
• Bodo D. Wilts

Beilstein J. Nanotechnol. 2025, 16, 1–10, doi:10.3762/bjnano.16.1

• -dimensional finite-difference time-domain (FDTD) method, using Ansys Lumerical 2024 R1 (Ansys Inc., Canonsburg, PA, USA). The diamond nanostructures were approximated via an idealized single diamond network approximated by triply periodic minimal surface model from its level-set equation [52]. Diamond

Fabrication of hafnium-based nanoparticles and nanostructures using picosecond laser ablation

• Abhishek Das,
• Mangababu Akkanaboina,
• Jagannath Rathod,
• R. Sai Prasad Goud,
• Kanaka Ravi Kumar,
• Raghu C. Reddy,
• Ratheesh Ravendran,
• Katia Vutova,
• S. V. S. Nageswara Rao and
• Venugopal Rao Soma

Beilstein J. Nanotechnol. 2024, 15, 1639–1653, doi:10.3762/bjnano.15.129

• /bjnano.15.129 Abstract This work presents a unique and straightforward method to synthesise hafnium oxide (HfO2) and hafnium carbide (HfC) nanoparticles (NPs) and to fabricate hafnium nanostructures (NSs) on a Hf surface. Ultrafast picosecond laser ablation of the Hf metal target was performed in three

• insight into their morphological and optical characteristics paving way for their applications in future. Keywords: hafnium; laser ablation in liquids; nanofibres; nanoparticles; nanostructures; Introduction Hafnium (Hf) is a tetravalent transition metal with compounds showing excellent thermal and

• and hexagonal phases were observed at higher input pulse energies. We believe these correspond to HfO2 and Hf6O, respectively. Further, in [10], we did not explore the formation of surface nanostructures on Hf after ablation. Therefore, the current study intends to understand the role of input pulse

Heterogeneous reactions in a HFCVD reactor: simulation using a 2D model

• Xochitl Aleyda Morán Martínez,
• José Alberto Luna López,
• Zaira Jocelyn Hernández Simón,
• Gabriel Omar Mendoza Conde,
• José Álvaro David Hernández de Luz and
• Godofredo García Salgado

Beilstein J. Nanotechnol. 2024, 15, 1627–1638, doi:10.3762/bjnano.15.128

• for the subsequent growth of the SiOx films. These SiOx films have interesting properties and embedded nanostructures, which make them excellent dielectric, optoelectronic, and electroacoustic materials for the fabrication of devices compatible with silicon-based technology. Keywords: 2D model

Biomimetic nanocarriers: integrating natural functions for advanced therapeutic applications

• Hugo Felix Perini,
• Beatriz Sodré Matos,
• Carlo José Freire de Oliveira and
• Marcos Vinicius da Silva

Beilstein J. Nanotechnol. 2024, 15, 1619–1626, doi:10.3762/bjnano.15.127

• drug absorption by the mononuclear phagocytic system due to its hydrophilic barrier [59]. Although PEG-coated nanostructures exhibit promising physicochemical properties, they have shown limitations; studies point to cases of hypersensitivity in PEGylated vaccines [60][61]. Potential adverse immune

• molecule bufalin and covered with platelet membranes demonstrated their ability to evade macrophage uptake and enhance binding to target cancer cells. Together, these results confirm the ability of biomimetic coated nanostructures to evade the immune system, enabling prolonged circulation time and

• , consequently, sustained and controlled release of potential associated drugs [21]. To overcome these limitations and enhance coating efficiency, the decoration of nanostructures with functional ligands increases their biological interactions. Decreasing nonspecific interactions and immunogenicity is one of the

Natural nanofibers embedded in the seed mucilage envelope: composite hydrogels with specific adhesive and frictional properties

• Agnieszka Kreitschitz and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2024, 15, 1603–1618, doi:10.3762/bjnano.15.126

• proper characterisation of their micro- and nanostructures. In the last years, SEM visualisation, combined with the critical point drying (CPD) procedure, has been widely used in nanostructural studies of diverse hydrogel-like samples, containing cellulose fibrils, or biofilms [7][40][41]. The CPD method

Ultrablack color in velvet ant cuticle

• Vinicius Marques Lopez,
• Wencke Krings,
• Juliana Reis Machado,
• Stanislav Gorb and
• Rhainer Guillermo-Ferreira

Beilstein J. Nanotechnol. 2024, 15, 1554–1565, doi:10.3762/bjnano.15.122

• spines and setae (Figure 4). The setae display nanostructures in the form of grooves and are hollow (Figure 4D). No morphological distinction was observed between white and black setae (Figure 4A). The cuticle is composed of overlapping lamellae with connective pillars and underlying layers (Figure 5

• ). The SEM and TEM images of the T. bifurca cuticle reveal that the cuticle sculpturing and setae together with the black pigment may facilitate structural light absorption (Figure 5). The setae in Figure 4, with their grooved nanostructures and hollow interiors, and the stacked lamellae (see L in Figure

• most probably coupled with melanin as in other velvet ants [24]. Similar cases of white–black structural colors can be observed in other insect groups. For instance, the tiger mosquito Aedes albopictus (Diptera: Culicidae) exhibits black and white scales with micro- and nanostructures that turn

Effect of radiation-induced vacancy saturation on the first-order phase transformation in nanoparticles: insights from a model

• Aram Shirinyan and
• Yuriy Bilogorodskyy

Beilstein J. Nanotechnol. 2024, 15, 1453–1472, doi:10.3762/bjnano.15.117

• , changes in the structural properties of Ni nanostructures due to ion bombardment have been reported in [15]. Interestingly, certain types of radiation ions have shown a positive effect on the crystal structure, leading to an increase in the degree of crystallinity after the austenitic annealing of defects

Ion-induced surface reactions and deposition from Pt(CO)₂Cl₂ and Pt(CO)₂Br₂

• Mohammed K. Abdel-Rahman,
• Patrick M. Eckhert,
• Atul Chaudhary,
• Johnathon M. Johnson,
• Jo-Chi Yu,
• Lisa McElwee-White and
• D. Howard Fairbrother

Beilstein J. Nanotechnol. 2024, 15, 1427–1439, doi:10.3762/bjnano.15.115

• Focused ion beam-induced deposition (FIBID) and focused electron beam-induced deposition (FEBID) are vacuum-based, charged-particle bottom-up nanofabrication techniques that directly fabricate metal containing nanostructures as a consequence of the reactions between ions or electrons and organometallic

• used as a precursor for creating pure Pt films during FIBID. However, using Pt(CO)2X2 as precursors for depositing nanostructures by means of FIBID will require gas injection systems that can be heated sufficiently to maintain a reasonable precursor partial pressure during deposition. Thus, the AES and

Lithium niobate on insulator: an emerging nanophotonic crystal for optimized light control

• Midhun Murali,
• Amit Banerjee and
• Tanmoy Basu

Beilstein J. Nanotechnol. 2024, 15, 1415–1426, doi:10.3762/bjnano.15.114

• manipulate the transmission of light modes, similar to how nanostructures have been utilized to regulate electron-related phenomena. Here we study the optical performance of a one-dimensional stacked photonic crystal based on LN and TiO2/SiO2. We studied the quarter wavelength multi-layered stack using

• from the visible to the infrared (400–5000 nm) [13]. The high degree of flexibility in fabrication created functional photonic nanostructures such as microring, periodically poled lithium niobate, and photonic crystals [14][15]. This versatility makes it suitable for DBRs to be used in various

Various CVD-grown ZnO nanostructures for nanodevices and interdisciplinary applications

• The-Long Phan,
• Le Viet Cuong,
• Vu Dinh Lam and
• Ngoc Toan Dang

Beilstein J. Nanotechnol. 2024, 15, 1390–1399, doi:10.3762/bjnano.15.112

• Institute of Research and Development, Duy Tan University, Da Nang 550000, Vietnam Faculty of Environmental and Natural Sciences, Duy Tan University, Da Nang 550000, Vietnam 10.3762/bjnano.15.112 Abstract This work presents a simple chemical vapour deposition (CVD) method to grow ZnO nanostructures. By

• results prove that ZnO exhibits many novel nanostructures that can foster the development of next-generation optoelectronic nanodevices and new applications in biological and biomedical fields. Keywords: chemical vapour deposition; electron microscopy; Raman and photoluminescent spectra; ZnO

• nanostructures; Introduction In recent decades, nanomaterials whose diameters are in the range of 1–100 nm have been of intensive interest because they exhibit dimension-dependent intriguing behaviours that are different from their bulk counterparts. These special behaviours come from quantum confinement and

Green synthesis of carbon dot structures from Rheum Ribes and Schottky diode fabrication

• Muhammed Taha Durmus and
• Ebru Bozkurt

Beilstein J. Nanotechnol. 2024, 15, 1369–1375, doi:10.3762/bjnano.15.110

• nanostructures are carbon dot structures (CDs). These structures have recently become a common field of study because of their properties including chemical stability, water solubility, and easy synthesis and functionalization. Carbon dots, were first discovered by Xu and his working group [1] while purifying

• nanostructures are obtained by using small nanoscale blocks. The hydrothermal synthesis method, which is a bottom-up method, is generally used in the synthesis of CDs. A very wide range of source materials, simple reaction equipment, and easy control of reaction conditions are the features that make this method

Hymenoptera and biomimetic surfaces: insights and innovations

• Vinicius Marques Lopez,
• Carlo Polidori and
• Rhainer Guillermo Ferreira

Beilstein J. Nanotechnol. 2024, 15, 1333–1352, doi:10.3762/bjnano.15.107

• of artificial surfaces, such as rough coatings on high-speed trains [12], dimples on golf balls [13], and shark skin denticles on aircrafts [14]. Some micromachines can also benefit from micro- and nanostructures that create roughness on surfaces and influence aerodynamics and heat transfer [15]. The

• these biomimetic materials. For instance, the cuticle of sawfly larvae has complex nanostructures and wax crystals that result in hydrophobicity [20]. By incorporating these properties, manufacturers may develop self-cleaning surfaces that maintain their low-friction characteristics even in harsh

• pheomelanin) [21][22][23] (but see [24][25] for other pigments). Especially structural coloration provides a wealth of inspiration for creating vivid, durable colors without the use of dyes. This natural phenomenon involves the manipulation of light by micro- and nanostructures on the cuticle (e.g

Nanoarchitectonics with cetrimonium bromide on metal nanoparticles for linker-free detection of toxic metal ions and catalytic degradation of 4-nitrophenol

• Akash Kumar and
• Raja Gopal Rayavarapu

Beilstein J. Nanotechnol. 2024, 15, 1312–1332, doi:10.3762/bjnano.15.106

• nanostructures were measured using an Epoch2 spectrophotometer (BioTek, USA). Hydrodynamic radius and polydispersity index (PDI) were measured using dynamic light scattering (Zetasizer Nano ZS, Malvern, UK). The zeta potential measurements were conducted to determine the surface charge for both isotropic and

• change in surface plasmon resonance of the metal nanostructures. A single absorbance peak correlates to the symmetrical shape and collective oscillation of free electrons on the nanoparticle surface. This phenomenon is known as localized surface plasmon resonance (LSPR), a characteristic feature of

Mn-doped ZnO nanopowders prepared by sol–gel and microwave-assisted sol–gel methods and their photocatalytic properties

• Cristina Maria Vlăduț,
• Crina Anastasescu,
• Silviu Preda,
• Oana Catalina Mocioiu,
• Simona Petrescu,
• Jeanina Pandele-Cusu,
• Dana Culita,
• Veronica Bratan,
• Ioan Balint and
• Maria Zaharescu

Beilstein J. Nanotechnol. 2024, 15, 1283–1296, doi:10.3762/bjnano.15.104

• 10.3762/bjnano.15.104 Abstract Although the microwave-assisted sol–gel method is quite frequently used for the preparation of oxide nanostructures, the synergism of the reaction pathways is not fully explained. However, state-of-the-art theoretical and practical results of high novelty can be achieved by

• photocatalysts; water depollution; Introduction Over the past decades, significant research has been focused on designing and preparing nanostructures of various shapes and sizes, which exhibit unique properties and potential applications [1]. Considerable advancements have been made in synthesizing

• preferred for synthesizing oxide nanostructures because of their advantages, such as uniform mixing of precursors at the molecular level, low operating temperatures, and the ability to control the physicochemical properties of the final products [5][6]. Among various chemical techniques, the sol–gel method

New design of operational MEMS bridges for measurements of properties of FEBID-based nanostructures

• Bartosz Pruchnik,
• Krzysztof Kwoka,
• Ewelina Gacka,
• Dominik Badura,
• Piotr Kunicki,
• Andrzej Sierakowski,
• Paweł Janus,
• Tomasz Piasecki and
• Teodor Gotszalk

Beilstein J. Nanotechnol. 2024, 15, 1273–1282, doi:10.3762/bjnano.15.103

• Photonics, Łukasiewicz Research Network, Lotników 32/46, 02-668, Warsaw, Poland 10.3762/bjnano.15.103 Abstract Focused electron beam-induced deposition (FEBID) is a novel technique for the development of multimaterial nanostructures. More importantly, it is applicable to the fabrication of free-standing

• nanostructures. Experimenting at the nanoscale requires instruments with sufficient resolution and sensitivity to measure various properties of nanostructures. Such measurements (regardless of the nature of the quantities being measured) are particularly problematic in the case of free-standing nanostructures

• surface or reduced capacitance) are brought by volumetric, self-standing electronic nanostructures, which provide an experimental basis for their own properties and can serve as building blocks for nanoscale devices, in which phenomena such as giant piezoresistivity, single-electron tunnelling, or field

Functional morphology of cleaning devices in the damselfly Ischnura elegans (Odonata, Coenagrionidae)

• Silvana Piersanti,
• Gianandrea Salerno,
• Wencke Krings,
• Stanislav Gorb and
• Manuela Rebora

Beilstein J. Nanotechnol. 2024, 15, 1260–1272, doi:10.3762/bjnano.15.102

• Abstract Among the different micro- and nanostructures located on cuticular surfaces, grooming devices represent fundamental tools for insect survival. The present study describes the grooming microstructures of the damselfly Ischnura elegans (Odonata, Coenagrionidae) at the adult stage. These structures

• portion and from the seta to the cuticular lamina. The removal of the grooming devices induces a strong increase in the contaminated areas on the eyes after grooming. Further studies on insect grooming can provide valuable data on the functional morphology of insect micro- and nanostructures and can

• tasks through the presence of micro- and nanostructures located on its cuticular surface, serving functions from sensory reception to surface adhesion, air retention, food grinding, thermoregulation, and color production (reviews in [4][5]). The insect cuticle is frequently exposed to a variety of

Realizing active targeting in cancer nanomedicine with ultrasmall nanoparticles

• André F. Lima,
• Giselle Z. Justo and
• Alioscka A. Sousa

Beilstein J. Nanotechnol. 2024, 15, 1208–1226, doi:10.3762/bjnano.15.98

• unique class of nanostructures for cancer nanomedicine, offering the potential to address significant limitations associated with larger particles, particularly in treating solid tumors. The incorporation of active targeting ligands onto usNPs holds the potential to enhance their performance in cancer

Synthesis, characterization and anticancer effect of doxorubicin-loaded dual stimuli-responsive smart nanopolymers

• Ömür Acet,
• Pavel Kirsanov,
• Burcu Önal Acet,
• Inessa Halets-Bui,
• Dzmitry Shcharbin,
• Şeyda Ceylan Cömert and
• Mehmet Odabaşı

Beilstein J. Nanotechnol. 2024, 15, 1189–1196, doi:10.3762/bjnano.15.96

• . Characterizations of the synthesized nanostructures were carried out including zeta potential measurements, Fourier-transform infrared spectroscopy, and scanning electron microscopy. The loading capacity of the nanopolymers for DOX was investigated, and encapsulation and release studies were carried out. In a final

• [9]. Certain designs in nanostructures are extremely useful to combat diseases [12][13]. Polymeric platforms have attracted great interest in recent years [14][15][16][17][18][19][20]. “Stimulus-sensitive” polymers (smart polymers) exhibit conformational changes or phase transition behavior in

• Centrifugen, USA). The precipitated nanostructures were redispersed in distilled water utilizing a sonicator and dried with a lyophilizer. Then, the nanostructures were stored at 4 °C. Characterization studies Functional group analysis was carried out by Fourier-transform infrared (FTIR) spectroscopy

AI-assisted models to predict chemotherapy drugs modified with C₆₀ fullerene derivatives

• Jonathan-Siu-Loong Robles-Hernández,
• Dora Iliana Medina,
• Katerin Aguirre-Hurtado,
• Marlene Bosquez,
• Roberto Salcedo and
• Alan Miralrio

Beilstein J. Nanotechnol. 2024, 15, 1170–1188, doi:10.3762/bjnano.15.95

• treatments that release substances at specific sites of interest, reducing the required drug amount and side effects. Nanostructures to form these drug delivery systems can be divided into organic and inorganic [19][20], with the latter one being the less extensively studied. One option currently considered

Local work function on graphene nanoribbons

• Daniel Rothhardt,
• Amina Kimouche,
• Tillmann Klamroth and
• Regina Hoffmann-Vogel

Beilstein J. Nanotechnol. 2024, 15, 1125–1131, doi:10.3762/bjnano.15.91

• ] and p-doping by Bi, Sb, and Au substrates [2]. Confining graphene to nanostructures [6][7], for example, to graphene nanoribbons (GNRs), that is, few nanometers wide stripes of graphene, opens additional possibilities of tuning the electronic properties by creating quantum-confined states [8] and

Direct electron beam writing of silver using a β-diketonate precursor: first insights

• Katja Höflich,
• Krzysztof Maćkosz,
• Chinmai S. Jureddy,
• Aleksei Tsarapkin and
• Ivo Utke

Beilstein J. Nanotechnol. 2024, 15, 1117–1124, doi:10.3762/bjnano.15.90

• Katja Hoflich Krzysztof Mackosz Chinmai S. Jureddy Aleksei Tsarapkin Ivo Utke Ferdinand-Braun-Institut (FBH), Gustav-Kirchhoff-Str. 4, 12489 Berlin, Germany Laboratory of Mechanics for Materials and Nanostructures, Empa – Swiss Federal Laboratories for Material Science and Technology

• , Feuerwerkerstrasse 39, CH 3602 Thun, Switzerland 10.3762/bjnano.15.90 Abstract Direct electron beam writing is a powerful tool for fabricating complex nanostructures in a single step. The electron beam locally cleaves the molecules of an adsorbed gaseous precursor to form a deposit, similar to 3D printing but

• . Keywords: focused electron beam-induced deposition; precursor; silver nanostructures; Introduction Direct writing with an electron beam allows for single-step and maskfree 3D printing of sophisticated nanostructures at the nanoscale [1][2][3][4]. The process relies on the electron beam-induced

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

• Shakhzodjon Uzokboev,
• Khojimukhammad Akhmadbekov,
• Ra’no Nuritdinova,
• Salah M. Tawfik and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

• , to mitigate limitations of simple nanostructures such as low stability and unsuitable drug release features. They investigated capsaicin-loaded alginate nanoparticles embedded in polycaprolactone–chitosan nanofiber mats. This DDS can extend the release time of capsaicin to more than 500 h compared to