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Search for "solubilization" in Full Text gives 27 result(s) in Beilstein Journal of Nanotechnology.
Efficiency of single-pulse laser fragmentation of organic nutraceutical dispersions in a circular jet flow-through reactor
Beilstein J. Nanotechnol. 2025, 16, 711–727, doi:10.3762/bjnano.16.55
- viability even at high curcumin concentrations. Keywords: antioxidant; cannabidiol; curcumin; drug; food additive; low degradation; nanoparticle; pulsed laser ablation in liquids; solubilization; Introduction Laser synthesis and processing of colloids (LSPC) has become increasingly popular over the last
- often are hydrophobic, is their increased solubilization or aqueous dispersion, relevant for pharmacological, photochemical, and photomedical applications. For example, metal complex phthalocyanines (Pc) [18] such as vanadium (VOPc) [19][20][21][22], copper (CuPc) [23][24], aluminum (AlPc) [24], and
Synthesis and the impact of hydroxyapatite nanoparticles on the viability and activity of rhizobacteria
Beilstein J. Nanotechnol. 2025, 16, 216–228, doi:10.3762/bjnano.16.17
- Tb-nHA sample. These findings correlate with the higher colony count of the Pd rhizobacterium strain as outlined in Table 2. Phosphate-solubilizing capability of rhizobacteria-nHA The proficiency of rhizobacteria in phosphate solubilization after inoculation on the nHA carrier for 21 days underscores
- state. Rhizobacteria demonstrate their ability to create transparent zones on Pikovskaya media because of their capability for phosphate solubilization. These microorganisms produce organic acids, such as citric acid and oxalic acid, which bind to phosphate via hydroxy groups and chelating cations such
- rhizobacteria, Pd and Tb rhizobacteria, decreased. nHA utilized as a carrier for rhizobacteria demonstrated good compatibility, as the loaded rhizobacteria retained their phosphate-solubilization activity, evident from the appearance of clear zones. Additionally, the nitrogen-fixing activity was maintained as
Isolation of cubic Si3P4 in the form of nanocrystals
Beilstein J. Nanotechnol. 2023, 14, 971–979, doi:10.3762/bjnano.14.80
- . Several techniques for functionalization and colloidal solubilization of Si3P4 NPs were outlined. Optical properties of the material were studied to reveal an experimental bandgap of 1.25 eV. Potential applications of the material include the preparation of microcircuits through the introduction of P
Quercetin- and caffeic acid-functionalized chitosan-capped colloidal silver nanoparticles: one-pot synthesis, characterization, and anticancer and antibacterial activities
Beilstein J. Nanotechnol. 2023, 14, 362–376, doi:10.3762/bjnano.14.31
- , while water-soluble MTT converts to an insoluble purple formazan. Therefore, MTT requires solubilization of insoluble formazan to determine its concentration by absorbance, whereas XTT does not require any solubilization. Therefore, the use of XTT is an excellent solution for the quantification of cells
Single-step extraction of small-diameter single-walled carbon nanotubes in the presence of riboflavin
Beilstein J. Nanotechnol. 2022, 13, 1564–1571, doi:10.3762/bjnano.13.130
- flavin adenine dinucleotide [16]. The presence of π-conjugated isoalloxazine in riboflavin drives binding to SWCNTs, and the hydrophilic ribityl chain allows for the solubilization of SWCNTs in aqueous media. The planar isoalloxazine structure, accompanied by intermolecular interactions with nanotubes
- to its low solubility in water, which leads to poor solubilization of SWCNT bundles. Lower riboflavin concentrations did not affect the dispersion process of nanotubes in any way. To analyze the dispersing ability of riboflavin, the same amount of SWCNTs was dispersed in 1% w/w SDS aqueous solution
Hydroxyapatite–bioglass nanocomposites: Structural, mechanical, and biological aspects
Beilstein J. Nanotechnol. 2022, 13, 1490–1504, doi:10.3762/bjnano.13.123
- , therefore, higher dissolution rate. HAP-based composites with a denser structure need a longer period of immersion in SBF for solubilization and the beginning of the mineralization process. And indeed, after 5 days of soaking, a well-pronounced precipitate was observed on HAP-based composites, too (Figure
Green synthesis of zinc oxide nanoparticles toward highly efficient photocatalysis and antibacterial application
Beilstein J. Nanotechnol. 2022, 13, 1108–1119, doi:10.3762/bjnano.13.94
- , proteins, DNA, and amino acids [39][40][41]. The O2 causes biomembrane oxidation reactions, damaging tissues [42]. Furthermore, it is reasonable to explain that the additional toxicity that causes bacterial death is due to the fact that zinc solubilization releases Zn2+ ions which can infiltrate into
Systematic studies into uniform synthetic protein nanoparticles
Beilstein J. Nanotechnol. 2022, 13, 274–283, doi:10.3762/bjnano.13.22
- . Paclitaxel was traditionally formulated through solubilization with harsh solvents, which led to adverse side effects and special administration instrumentation [9]. While AbraxaneTM was first FDA-approved for the treatment of metastatic breast cancer, it has since been investigated for other cancers
Use of nanosystems to improve the anticancer effects of curcumin
Beilstein J. Nanotechnol. 2021, 12, 1047–1062, doi:10.3762/bjnano.12.78
- Conventional nanosystems are particularly attractive for the biopharmaceutics classification system (BCS) class IV drugs, such as CUR, which require increases in their solubilization, pharmacokinetics, and permeation [43]. Curcumin has been targeted against carcinogenic lesions in the colon, skin, cervix
A review on nanostructured silver as a basic ingredient in medicine: physicochemical parameters and characterization
Beilstein J. Nanotechnol. 2021, 12, 440–461, doi:10.3762/bjnano.12.36
- ]. Separation of AgNPs from Ag+: The cloud point extraction (CPE) technique was initiated by Goto et al. and it is based on the solubilization capacity and on the cloud point of nonionic surfactants [148]. At the cloud point, the instability observed in the micelles is promoted by the dehydration of the
Key for crossing the BBB with nanoparticles: the rational design
Beilstein J. Nanotechnol. 2020, 11, 866–883, doi:10.3762/bjnano.11.72
- [27]. The liquid lipid phase allows for a better solubilization of APIs and thus for a higher drug loading capacity than that of SLNs [168]. NLCs loaded with itraconazole prepared with PS80 were able to almost double the itraconazole concentration in the brain compared to the drug alone [169]. In
Rational design of block copolymer self-assemblies in photodynamic therapy
Beilstein J. Nanotechnol. 2020, 11, 180–212, doi:10.3762/bjnano.11.15
- then the ones for the hydrophilic block. In the former case, the photosensitizer can be simply solubilized in the interior of the self-assemblies or covalently linked to the copolymer backbone. Physical solubilization of the photosensitizer The structures, features and applications of block copolymers
- used for the physical solubilization of photosensitizers are described in this section and summarized below in Table 1. Most commonly applied are biocompatible, nontoxic and FDA-approved copolymers, such as pluronics [30][31][32][33][34][35] or biodegradable aliphatic polyesters, based for instance on
- backbone is known to be biocompatible, as demonstrated by its long use in opthalmology [44]. Counterintuitively, as it will be detailed in the next section, the introduction of aromatic units is not always an advantage [45]. In order to improve the solubilization of the photosensitizer, other interactions
Molecular architectonics of DNA for functional nanoarchitectures
Beilstein J. Nanotechnol. 2020, 11, 124–140, doi:10.3762/bjnano.11.11
- solubilization and weak alignment of proteins within plasma membrane are crucial to measure the residual dipolar couplings (RDCs), and the RDCs are crucial to obtain NMR structural information on membrane-bound proteins. As reported, DNA origami-based liquid crystalline media can overcome detergent-related
Design of a nanostructured mucoadhesive system containing curcumin for buccal application: from physicochemical to biological aspects
Beilstein J. Nanotechnol. 2019, 10, 2304–2328, doi:10.3762/bjnano.10.222
- hexagonal core with ordered structure, which enable the solubilization of hydrophilic and hydrophobic drugs [4][5][6][7][8][9]. Moreover, C974P is an acrylic-acid derivative, highly cross-linked, hydrophilic, and displays mucoadhesive properties [1]. In this sense, an increase in temperature promotes the
Gold-coated plant virus as computed tomography imaging contrast agent
Beilstein J. Nanotechnol. 2019, 10, 1983–1993, doi:10.3762/bjnano.10.195
- and size, indicating that they are resistant to solubilization or oxidation. The dual STEM and EDX spectra from the Antibody-PEG5000Au-CPMV gave useful information about the spatial distribution of gold and sulfur across the cellular surface. The simultaneously acquired EDX spectrum images confirmed
Nanoconjugates of a calixresorcinarene derivative with methoxy poly(ethylene glycol) fragments for drug encapsulation
Beilstein J. Nanotechnol. 2018, 9, 2057–2070, doi:10.3762/bjnano.9.195
- . The fluorescence emission of naproxen sodium is quenched in the presence of macrocycle and does not change in the presence of mPEG-550 (Figure S12, Supporting Information File 1). This is evidence for the binding of Nap near the aromatic fragments of macrocycle. After the solubilization of IF and Nap
- solutions in D2O; (b) 1H NMR spectra of IF and 3 + IF solutions in D2O; (c) intensity-averaged particle size distribution of aqueous solutions of 3 in the absence and the presence of Nap and IF (solubilization method, c3 = 10 mg/mL). In vitro release profiles of free RhB and RhB-loaded micelles of 3 in PBS
Surfactant-induced enhancement of droplet adhesion in superhydrophobic soybean (Glycine max L.) leaves
Beilstein J. Nanotechnol. 2017, 8, 2345–2356, doi:10.3762/bjnano.8.234
- solubilization of the waxes and gas chromatography (GC–FID) and mass spectroscopy (GC–MS). Results Micromorphology of the leaf surface The micromorphology of leaf surfaces was investigated by scanning electron microscopy (SEM) and 3D light microscopy. Trichomes, commonly termed hairs, are slightly tilted, up to
Dispersion of single-wall carbon nanotubes with supramolecular Congo red – properties of the complexes and mechanism of the interaction
Beilstein J. Nanotechnol. 2017, 8, 636–648, doi:10.3762/bjnano.8.68
- engineering [10][11][12]. Pristine CNTs exist in form of bundles composed of hundreds of single tubes bound by van der Waals interactions. Most applications of carbon nanotubes require their dispersion (solubilization) which can be achieved by either covalent or noncovalent functionalization [8][13][14
- performed by sonication of pristine CNTs in an amphiphilic solution. Sonication leads both to the solubilization and shortening of carbon nanotubes. Shortening, resulting from long-term sonication, takes place at sites of structural defects present on nanotube surface. It is important to note that the
Nanoscale isoindigo-carriers: self-assembly and tunable properties
Beilstein J. Nanotechnol. 2017, 8, 313–324, doi:10.3762/bjnano.8.34
- hydropohobic solutes including drugs. Furthermore, the solubilization of organic hydrophobic dyes makes it possible to detect the formation of micelles in solution [67]. In Figure 4a, the dependence of the absorbance of hydrophobic dye (Sudan I) on the concentration of isoindigo derivatives 2g and 2h is shown
- ) and 0.1 mМ (for 2h). Thus, experimental data prove the formation of self-assembled structures of 2g and 2h with a hydrophobic field that can dissolve nonpolar probes. The critical association concentrations for 2g and 2h are 0.2 and 0.1 mМ, respectively. Calculated values of the solubilization
- capacity of 2g and 2h micellar aggregates are given in Table S4 (Supporting Information File 1). As can be seen, the solubilization capacity value grows with the increasing length of the alkyl chain. According to Table S4 (Supporting Information File 1), the solubilization ability of 2g and 2h is
Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling
Beilstein J. Nanotechnol. 2016, 7, 1905–1917, doi:10.3762/bjnano.7.182
- ]. Solubilization of these clusters in water leads to micellar peptization and colloidal sol formation; peptization increases with temperature and dilution. The colloidal nature of the final O-dots solution can be demonstrated easily by the Tyndall cone arising at wavelengths where absorption is absent, for example
Heterometal nanoparticles from Ru-based molecular clusters covalently anchored onto functionalized carbon nanotubes and nanofibers
Beilstein J. Nanotechnol. 2015, 6, 1287–1297, doi:10.3762/bjnano.6.133
- phosphine-functionalized nanocarbons by stirring in a mixture of toluene and dichloromethane. Toluene is chosen to maximize interactions with the carbon support and dichloromethane to ensure solubilization of the metal species. The total metal loading is determined in each case by Ru, Co, Pt and/or Au ICP
The impact of the confinement of reactants on the metal distribution in bimetallic nanoparticles synthesized in reverse micelles
Beilstein J. Nanotechnol. 2014, 5, 1966–1979, doi:10.3762/bjnano.5.206
- into account the surface composition (Au or Pt). Another type of growth is Ostwald ripening, that is, the growth of larger particles at the expense of smaller ones by transport of material. It is assumed that the easier solubilization of the smallest particles causes their decrease in size. These atoms
Non-covalent and reversible functionalization of carbon nanotubes
Beilstein J. Nanotechnol. 2014, 5, 1675–1690, doi:10.3762/bjnano.5.178
- applications in fields such as material science, drug delivery and diagnostic applications. Their versatile physicochemical features are nonetheless limited by their scarce solubilization in both aqueous and organic solvents. In order to overcome this drawback CNTs can be easily non-covalently functionalized
- functionalization of MWCNTs makes use of molecules that self-assemble around the nanotube forming supramolecular polymers. Llanes-Pallas et al. have shown that such a non-covalent solubilization can be realized by exploiting the formation of hydrogen bonds between the 2,6-di(acetylamino)pyridine and the imidic
- favorably exploited for CNTs precipitation/dispersion cycles. Ortiz-Acevedo et al. obtained a diameter-selective solubilization of SWCNTs by using cyclic peptides containing thiol groups [101]. The oxidation induces polymerization of the peptides which wrap around the nanotube achieving a size-selective
In vitro interaction of colloidal nanoparticles with mammalian cells: What have we learned thus far?
Beilstein J. Nanotechnol. 2014, 5, 1477–1490, doi:10.3762/bjnano.5.161
- prediction of NP interactions, for instance, in the human body or in ecotoxicology. Some NPs have been mistaken to elicit limited to no adverse effects upon zebrafish assays, as they had precipitated to the bottom, and thus, the fish had not been directly exposed to them. After correct solubilization
Morphological characterization of fullerene–androsterone conjugates
Beilstein J. Nanotechnol. 2014, 5, 374–379, doi:10.3762/bjnano.5.43
- ][7], nucleotides, sugars and steroids [8][9], have allowed the solubilization of these hybrid derivatives in aqueous media, thus enhancing certain biological activities. For the potential use of C60 derivatives as drug delivery systems, the size of the particles is important. In general, fast drug
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