Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

• Shakhzodjon Uzokboev,
• Khojimukhammad Akhmadbekov,
• Ra’no Nuritdinova,
• Salah M. Tawfik and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

• a linear dynamic range of 0 to 1250 μM, with a LOD of 14 μM. Based on the selective enzymatic release of H2O2, the developed solid kit could be used to detect many biomarkers, including glucose, lactate, uric acid, and cholesterol [118]. Humidity sensing: One area that has shown promise in the field

Recent progress on field-effect transistor-based biosensors: device perspective

• Billel Smaani,
• Fares Nafa,
• Mohamed Salah Benlatrech,
• Ismahan Mahdi,
• Hamza Akroum,
• Mohamed walid Azizi,
• Khaled Harrar and
• Sayan Kanungo

Beilstein J. Nanotechnol. 2024, 15, 977–994, doi:10.3762/bjnano.15.80

• -enzymatic targeting detection of uric acid in serum and urine. In this sense, the authors developed an enzymatic potentiometric technique that can be employed for the accurate determination of uric acid density in human urine and serum. In this context, the detection of uric acid is achieved by the

• -end biosensing parts are made using gold electrode material and manufactured by a lithography process, liftoff technique, and metal evaporation process. It has been indicated that the proposed EG FET-based biosensors exhibit super selectivity and high sensitivity for a reliable detection of uric acid

Simultaneous electrochemical determination of uric acid and hypoxanthine at a TiO₂/graphene quantum dot-modified electrode

• Vu Ngoc Hoang,
• Dang Thi Ngoc Hoa,
• Nguyen Quang Man,
• Le Vu Truong Son,
• Le Van Thanh Son,
• Vo Thang Nguyen,
• Le Thi Hong Phong,
• Ly Hoang Diem,
• Kieu Chan Ly,
• Ho Sy Thang and
• Dinh Quang Khieu

Beilstein J. Nanotechnol. 2024, 15, 719–732, doi:10.3762/bjnano.15.60

• composite (TiO2/GQDs) obtained by in situ synthesis of GQDs, derived from coffee grounds, and peroxo titanium complexes was used as electrode modifier in the simultaneous electrochemical determination of uric acid and hypoxanthine. The TiO2/GQDs material was characterized by photoluminescence, X-ray

• diffraction, Raman spectroscopy, high-resolution transmission electron microscopy, and energy-dispersive X-ray mapping. The TiO2/GQDs-GCE exhibits better electrochemical activity for uric acid and hypoxanthine than GQDs/GCE or TiO2/GCE in differential pulse voltammetry (DPV) measurements. Under optimized

• conditions, the calibration plots were linear in the range from 1.00 to 15.26 μM for both uric acid and hypoxanthine. The limits of detection of this method were 0.58 and 0.68 μM for uric acid and hypoxanthine, respectively. The proposed DPV method was employed to determine uric acid and hypoxanthine in

A non-enzymatic electrochemical hydrogen peroxide sensor based on copper oxide nanostructures

• Irena Mihailova,
• Vjaceslavs Gerbreders,
• Marina Krasovska,
• Eriks Sledevskis,
• Valdis Mizers,
• Andrejs Bulanovs and
• Andrejs Ogurcovs

Beilstein J. Nanotechnol. 2022, 13, 424–436, doi:10.3762/bjnano.13.35

• interfering substances, that is, ascorbic acid, uric acid, dopamine, NaCl, glucose, and acetaminophen, do not affect the electrochemical response. The real milk sample test showed a high recovery rate (more than 95%). According to the obtained results, this sensor is suitable for practical use for the

• ), uric acid (C5H4N4O3, CAS number: 69-93-2), dopamine hydrochloride ((HO)2C6H3CH2CH2NH2HCl, CAS number: 62-31-7), glucose (C6H12O6, CAS number: 50-99-7), acetaminophen (CH3CONHC6H4OH, CAS number: 103-90-2), and sodium chloride (NaCl, CAS number: 7647-14-5) were purchased from Sigma-Aldrich. All reagents

• NaOH was used. The experiment was started at 0 µM concentration of H2O2, then every 60 s either H2O2 or an interfering substance at a concentration of 100 µM was added to the solution, in the following order: H2O2, ascorbic acid, uric acid, dopamine, NaCl, glucose, and acetaminophen. Then, the whole

The role of Ag⁺, Ca²⁺, Pb²⁺ and Al³⁺ adions in the SERS turn-on effect of anionic analytes

• Stefania D. Iancu,
• Andrei Stefancu,
• Vlad Moisoiu,
• Loredana F. Leopold and
• Nicolae Leopold

Beilstein J. Nanotechnol. 2019, 10, 2338–2345, doi:10.3762/bjnano.10.224

• uric acid, salicylic acid and fumaric acid could be recorded at a concentration of 50 µM only after activation of the colloidal silver nanoparticles by Ca2+, Pb2+ or Al3+ (50 µM). The chemisorption of the three anionic species to the silver surface occurs competitively and is enhanced with the anions

• . We probed this methodology on three organic acids: uric acid, salicylic acid and fumaric acid. Uric acid is a metabolite present in biofluids such as blood serum (0.2–0.4 mM) [31], urine or saliva. The SERS spectra of these biofluids are dominated by uric acid and other purine metabolite bands due to

• the high affinity of these metabolites for the silver surface. Because the affinity of uric acid to the AgNPs is higher than that of chloride, uric acid can be detected by SERS also with chloride containing colloids [24][26]. However, at low concentrations such as 50 µM, neither uric acid nor fumaric

The systemic effect of PEG-nGO-induced oxidative stress in vivo in a rodent model

• Qura Tul Ain,
• Samina Hyder Haq,
• Abeer Alshammari,
• Moudhi Abdullah Al-Mutlaq and
• Muhammad Naeem Anjum

Beilstein J. Nanotechnol. 2019, 10, 901–911, doi:10.3762/bjnano.10.91

• activity of GO [17]. Moreover, GO-based sensors have been used for the detection of neonicotinoids [18], tyrosine [19], ascorbic acid, dopamine, uric acid [20], 4-nitrophenol [21], and glucose [22]. Among all biocompatible polymers, PEG has been extensively used as a GO cover. Feng et al. used PEG and PEI

Voltammetric determination of polyphenolic content in pomegranate juice using a poly(gallic acid)/multiwalled carbon nanotube modified electrode

• Refat Abdel-Hamid and
• Emad F. Newair

Beilstein J. Nanotechnol. 2016, 7, 1104–1112, doi:10.3762/bjnano.7.103

• stress [2]. A facile and ultrasensitive sensor based on gold microclusters electrodeposited on sulfonate-functionalized graphene that was immobilized on the surface of a GCE was fabricated and applied for the simultaneous determination of gallic acid and uric acid [3]. The electrochemical mechanism and

Sequence-dependent electrical response of ssDNA-decorated carbon nanotube, field-effect transistors to dopamine

• Hari Krishna Salila Vijayalal Mohan,
• Jianing An and
• Lianxi Zheng

Beilstein J. Nanotechnol. 2014, 5, 2113–2121, doi:10.3762/bjnano.5.220

• FETs lack responsivity and selectivity for its detection due to the presence of interfering compounds such as uric acid (UA). Surface modification of CNTs using single-stranded deoxyribonucleic acid (ssDNA) renders the surface responsive to DA and screens the interferent. Due to the presence of

• : carbon nanotube; deoxyribonucleic acid; dopamine; field-effect transistor; uric acid; Introduction Single-walled carbon nanotubes (SWCNTs) are excellent chemical/biological sensing materials because of their ultra-high sensitivity, fast response, and size compatibility, as compared to traditional

• [4]. However, the presence of interfering compounds such as ascorbic acid (AA) and uric acid (UA) is a major cause for poor response and selectivity in SWCNT-based sensors in the detection of DA. Moreover, current electrochemical methods for CNT-based DA detection suffer from low sensitivity [5][6][7

Carbon nano-onions (multi-layer fullerenes): chemistry and applications

• Juergen Bartelmess and
• Silvia Giordani

Beilstein J. Nanotechnol. 2014, 5, 1980–1998, doi:10.3762/bjnano.5.207

• in the presence of ascorbic acid and uric acid in solution [44]. The concentration of dopamine could be determined in a range between 5 × 10−5 and 4 × 10−3 mol·L−1. They also reported the in situ polymerization of aniline on phenylene amine-terminated CNO derivatives [45]. This polyaniline (PANI

A catechol biosensor based on electrospun carbon nanofibers

• Dawei Li,
• Zengyuan Pang,
• Xiaodong Chen,
• Lei Luo,
• Yibing Cai and
• Qufu Wei

Beilstein J. Nanotechnol. 2014, 5, 346–354, doi:10.3762/bjnano.5.39

• /CNFs showed excellent electrocatalytic activities towards dopamine (DA), uric acid (UA) and ascorbic acid (AA) [26]. NiCF-paste (NiCFP) electrodes displayed excellent electrocatalytic capacity for the oxidation of glucose [27]. These works indicate that electrospun CNFs (ECNFs) harbor excellent