Synthetic-polymer-assisted antisense oligonucleotide delivery: targeted approaches for precision disease treatment

• Ana Cubillo Alvarez,
• Dylan Maguire and
• Ruairí P. Brannigan

Beilstein J. Nanotechnol. 2025, 16, 435–463, doi:10.3762/bjnano.16.34

• [111]. Thanks to the ability of PEI to efficiently bind negatively charged macromolecules and overcome cellular barriers, PEI-based systems have been extensively investigated for targeted antisense oligonucleotide and gene delivery. In 2011, Yang et al. studied the bioactivity in vitro and in vivo of

A review of metal-organic frameworks and polymers in mixed matrix membranes for CO₂ capture

• Charlotte Skjold Qvist Christensen,
• Nicholas Hansen,
• Mahboubeh Motadayen,
• Nina Lock,
• Martin Lahn Henriksen and
• Jonathan Quinson

Beilstein J. Nanotechnol. 2025, 16, 155–186, doi:10.3762/bjnano.16.14

Realizing active targeting in cancer nanomedicine with ultrasmall nanoparticles

• André F. Lima,
• Giselle Z. Justo and
• Alioscka A. Sousa

Beilstein J. Nanotechnol. 2024, 15, 1208–1226, doi:10.3762/bjnano.15.98

• ][168]. The prevalence of silica-based NPs in these trials is justified by their FDA approval as an investigational new drug for oncologic applications since 2011. Table 3 lists the usNPs in clinical development, as found on the website https://ClinicalTrials.gov. Conclusion Ultrasmall NPs represent a

AI-assisted models to predict chemotherapy drugs modified with C₆₀ fullerene derivatives

• Jonathan-Siu-Loong Robles-Hernández,
• Dora Iliana Medina,
• Katerin Aguirre-Hurtado,
• Marlene Bosquez,
• Roberto Salcedo and
• Alan Miralrio

Beilstein J. Nanotechnol. 2024, 15, 1170–1188, doi:10.3762/bjnano.15.95

• mortality rate from breast cancer has been reduced by 1.9% annually from 2002 to 2011 and 1.3% from 2011 to 2020 [5]. Diagnostics and treatments have continuously improved through the years. However, the situation is different in each country considering the costs and technological advances in each country

Photocatalytic methane oxidation over a TiO₂/SiNWs p–n junction catalyst at room temperature

• Qui Thanh Hoai Ta,
• Luan Minh Nguyen,
• Ngoc Hoi Nguyen,
• Phan Khanh Thinh Nguyen and
• Dai Hai Nguyen

Beilstein J. Nanotechnol. 2024, 15, 1132–1141, doi:10.3762/bjnano.15.92

• ://creativecommons.org/licenses/by/4.0). Both structures were combined using the Vesta software (Momma, K.; Izumi, F. J. Appl. Crystallogr. 2011, 44, 1272–1276). Funding Ta Thanh Hoai Qui was funded by the Postdoctoral Scholarship Programme of Vingroup Innovation Foundation (VINIF), code VINIF.2023.STS.62. Competing

Entry of nanoparticles into cells and tissues: status and challenges

• Kirsten Sandvig,
• Tore Geir Iversen and
• Tore Skotland

Beilstein J. Nanotechnol. 2024, 15, 1017–1029, doi:10.3762/bjnano.15.83

• scale bar is 100 nm. Figure 2 was reprinted from [29], Current Opinion in Cell Biology, vol. 23, by K. Sandvig; S. Pust; T. Skotland; B. van Deurs, “Clathrin-independent endocytosis: mechanisms and function“, pages 413-420, Copyright (2011), with permission from Elsevier. This content is not subject to

Fabrication of nanocrystal forms of ᴅ-cycloserine and their application for transdermal and enteric drug delivery systems

• Hsuan-Ang Tsai,
• Tsai-Miao Shih,
• Theodore Tsai,
• Jhe-Wei Hu,
• Yi-An Lai,
• Jui-Fu Hsiao and
• Guochuan Emil Tsai

Beilstein J. Nanotechnol. 2024, 15, 465–474, doi:10.3762/bjnano.15.42

• housing, experimentation, and animal disposal were performed in general accordance with the Guide for the Care and Use of Laboratory Animals (National Academy Press, Washington, DC, 2011). In addition, Eurofins (Taiwan site) conducted the animal studies. Eight-week-old Sprague Dawley rats were randomly

Nanotechnological approaches in the treatment of schistosomiasis: an overview

• Lucas Carvalho,
• Michelle Sarcinelli and
• Beatriz Patrício

Beilstein J. Nanotechnol. 2024, 15, 13–25, doi:10.3762/bjnano.15.2

• have also been found in our search. Miltefosine, for example, is a drug created to treat cutaneous metastasis from mammary carcinomas [68]. After that, it was also approved to treat leishmaniasis [69][70], and in 2011, Eissa et al. [71] verified that the drug has activity against different forms of S

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

• Elangovan Sarathkumar,
• Rajasekharan S. Anjana and
• Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

• Commons Attribution 4.0 International License, https://creativecommons.org/licenses/by/4.0).). TEM images of gold crosses (E). (Figure 6D and E was reprinted with permission from [62], Copyright 2011 American Chemical Society. This content is not subject to CC BY 4.0.). Absorbance and TEM images of

Straight roads into nowhere – obvious and not-so-obvious biological models for ferrophobic surfaces

• Wilfried Konrad,
• Christoph Neinhuis and
• Anita Roth-Nebelsick

Beilstein J. Nanotechnol. 2022, 13, 1345–1360, doi:10.3762/bjnano.13.111

• ), https://gepris.dfg.de/gepris/projekt/39399990/ergebnisse “Energy self-sufficient fibre based long-distance transport of liquids”, 2008–2011. Participants: University of Tübingen, Institut für Textil- und Verfahrenstechnik (Denkendorf), Helmholtz-Zentrum (Berlin), TWD Fibres GmbH (Deggendorf), funded by

Recent trends in Bi-based nanomaterials: challenges, fabrication, enhancement techniques, and environmental applications

• Vishal Dutta,
• Ankush Chauhan,
• Ritesh Verma,
• C. Gopalkrishnan and
• Van-Huy Nguyen

Beilstein J. Nanotechnol. 2022, 13, 1316–1336, doi:10.3762/bjnano.13.109

• synthesizing and applying a semiconductor photocatalyst have been published in recent years. A survey on bismuth-based nanocomposites with the search keywords "Bismuth-based nanoparticles for environmental remediation" from 2011 to 2021 yields roughly 15,995 articles. This data illustrates the interest of the

Zinc oxide nanostructures for fluorescence and Raman signal enhancement: a review

• Ioana Marica,
• Fran Nekvapil,
• Maria Ștefan,
• Cosmin Farcău and
• Alexandra Falamaș

Beilstein J. Nanotechnol. 2022, 13, 472–490, doi:10.3762/bjnano.13.40

Engineered titania nanomaterials in advanced clinical applications

• Padmavati Sahare,
• Paulina Govea Alvarez,
• Juan Manual Sanchez Yanez,
• Gabriel Luna-Bárcenas,
• Samik Chakraborty,
• Sujay Paul and
• Miriam Estevez

Beilstein J. Nanotechnol. 2022, 13, 201–218, doi:10.3762/bjnano.13.15

Sputtering onto liquids: a critical review

• Anastasiya Sergievskaya,
• Adrien Chauvin and
• Stephanos Konstantinidis

Beilstein J. Nanotechnol. 2022, 13, 10–53, doi:10.3762/bjnano.13.2

Morphology-driven gas sensing by fabricated fractals: A review

• Vishal Kamathe and
• Rupali Nagar

Beilstein J. Nanotechnol. 2021, 12, 1187–1208, doi:10.3762/bjnano.12.88

• . Similar observations on the importance of network interconnectivity have been made by Chen et al. as discussed above. In 2011, Phadungdhitidhada et al. prepared SnO2 NWs of different diameters (from 50–150 nm) with and without nanodendrites (NDs), with lengths extending to a few tens of micrometers and

• nanowires mixed nanodendrites for high ethanol sensor response”, pages no. 1368–1373, Copyright (2011), with permission from Elsevier. This content is not subject to CC BY 4.0. SnO2/CuO nanoscale hybrid dendrites. SEM images of (a) Sn–Cu porous foams, (b) the 3D interlock network structure of the as

Physical constraints lead to parallel evolution of micro- and nanostructures of animal adhesive pads: a review

• Thies H. Büscher and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2021, 12, 725–743, doi:10.3762/bjnano.12.57

• from Springer Nature from “Biological fibrillar adhesives: functional principles and biomimetic applications. In: Handbook of Adhesion Technology” by S. N. Gorb, Copyright 2011 Springer Nature. This content is not subject to CC BY 4.0). (C) Dependence of the contact density of terminal contacts on the

• Adhesion Technology” by S. N. Gorb, Copyright 2011 Springer Nature. This content is not subject to CC BY 4.0. Figure 7D was adapted from [129] with permission from The Royal Society (U.K.), from Proc. R. Soc. B, S. N. Gorb, vol. 267, issue 1449, Copyright 2000; permission conveyed through Copyright

• . In: Handbook of Adhesion Technology” by S. N. Gorb, Copyright 2011 Springer Nature. This content is not subject to CC BY 4.0.). (C) Chemical composition (absolute concentration of substance groups) of the pad secretion of the smooth euplantulae of Locusta migratoria (Figure 8C was adapted from [254

Nanogenerator-based self-powered sensors for data collection

• Yicheng Shao,
• Maoliang Shen,
• Yuankai Zhou,
• Xin Cui,
• Lijie Li and
• Yan Zhang

Beilstein J. Nanotechnol. 2021, 12, 680–693, doi:10.3762/bjnano.12.54

• capability can be enhanced. Moreover, AI technology can also enhance the performance of sensor. Traffic sensors PENGs are also applicable in intelligent transportation systems. Self-powered vehicle sensors based on PENGs/TENGs can collect the signal of force changes when the vehicle status changes. In 2011

• ]. Copyright © 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim. Used with permission from Caofeng Pan et al., “Fiber‐Based Hybrid Nanogenerators for/as Self‐Powered Systems in Biological Liquid”, Angewandte Chemie International Edition, John Wiley and Sons. (f) Output of the hybrid system under different

• Society. NG-based self-powered traffic sensor. (a) PENG attached to a tire with adhesive tape [5]. Figure 6a,b was reproduced from [5]. Copyright © 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim. Used with permission from Youfan Hu et al., “A Nanogenerator for Energy Harvesting from a Rotating Tire and

A review of defect engineering, ion implantation, and nanofabrication using the helium ion microscope

• Frances I. Allen

Beilstein J. Nanotechnol. 2021, 12, 633–664, doi:10.3762/bjnano.12.52

ZnO and MXenes as electrode materials for supercapacitor devices

• Ameen Uddin Ammar,
• Ipek Deniz Yildirim,
• Feray Bakan and
• Emre Erdem

Beilstein J. Nanotechnol. 2021, 12, 49–57, doi:10.3762/bjnano.12.4

• because of its unique properties, such as ultrathin structure and heterojunction behavior [15]. In the search of other 2D materials, MXenes, which are a novel class of 2D metal carbides, were discovered at Drexel University in 2011 during research in which MAX phases were used as electrode materials in

Bio-imaging with the helium-ion microscope: A review

• Matthias Schmidt,
• James M. Byrne and
• Ilari J. Maasilta

Beilstein J. Nanotechnol. 2021, 12, 1–23, doi:10.3762/bjnano.12.1

• HIM in the field of medicine came in 2011 when Bazou et al. used the HIM to study tumor cells [9][10] and Arey et al. studied the interaction of nanoparticles with alveolar epithelial cells [11]. In the following two years, reports on HIM imaging of the nanostructures on butterfly scales by Boden et

• preparation treatments should be applied to best image a sample. HIM in medical research Besides the example micrograph of a white blood cell published by Ward et al. in 2007 [2], the usage of HIM for medical studies did not begin until around 2011 when Arey et al. reported on the interaction of alveolar

• epithelial cells with silica nanoparticles with HIM at the Microscopy and Microanalytics Conference 2011 [11]. In their abstract, they suggested that Rutherford back-scattering imaging in the HIM enables the distinction of nanoparticles from cell surface structures at nanometre resolution. In a different

Applications of superparamagnetic iron oxide nanoparticles in drug and therapeutic delivery, and biotechnological advancements

• Maria Suciu,
• Corina M. Ionescu,
• Alexandra Ciorita,
• Septimiu C. Tripon,
• Dragos Nica,
• Hani Al-Salami and
• Lucian Barbu-Tudoran

Beilstein J. Nanotechnol. 2020, 11, 1092–1109, doi:10.3762/bjnano.11.94

• ][147] as H·f ≤ C, with C = 5·109 A·m−1·s−1. A study from 2007 showed that the best conditions regarding safety and hyperthermia effect can be obtained at f = 400 kHz [148]. A significant increase of temperature might not be required for killing cancer cells, as Creixell and collaborators showed in 2011

Multilayer capsules made of weak polyelectrolytes: a review on the preparation, functionalization and applications in drug delivery

• Varsha Sharma and
• Anandhakumar Sundaramurthy

Beilstein J. Nanotechnol. 2020, 11, 508–532, doi:10.3762/bjnano.11.41

Facile biogenic fabrication of hydroxyapatite nanorods using cuttlefish bone and their bactericidal and biocompatibility study

• Satheeshkumar Balu,
• Manisha Vidyavathy Sundaradoss,
• Swetha Andra and
• Jaison Jeevanandam

Beilstein J. Nanotechnol. 2020, 11, 285–295, doi:10.3762/bjnano.11.21

• with tissue. Further, Jadalannagari et al. (2011) and Zanotto et al. (2012) synthesized Hap NRs with smaller width and length via sol–gel and precipitation approaches, respectively [43][44], as compared to the present study. However, it is noteworthy that the biogenic fabrication of nanometer-sized Hap

Using gold nanoparticles to detect single-nucleotide polymorphisms: toward liquid biopsy

• María Sanromán Iglesias and
• Marek Grzelczak

Beilstein J. Nanotechnol. 2020, 11, 263–284, doi:10.3762/bjnano.11.20

• of linker DNA strands by a few initial target molecules leads to the preservation of the colloidal stability of gold nanoparticles. In the absence of a target, the intact linker DNA hybridizes with Au@DNA leading to a gradual color change. Reprinted with permission from [108], copyright 2011 Elsevier

• oligonucleotides. The presence of a mutation decreases the fluorescence of the CdS films by nearly 90%. Reprinted with permission from [121], copyright 2011 Royal Society of Chemistry. Colorimetric DNA detection through rolling circle amplification (RCA) and NEase-assisted nanoparticle amplification (NEANA). a

Rational design of block copolymer self-assemblies in photodynamic therapy

• Maxime Demazeau,
• Laure Gibot,
• Anne-Françoise Mingotaud,
• Patricia Vicendo,
• Clément Roux and
• Barbara Lonetti

Beilstein J. Nanotechnol. 2020, 11, 180–212, doi:10.3762/bjnano.11.15