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Beilstein J. Org. Chem. 2024, 20, 1088–1098, doi:10.3762/bjoc.20.96
Graphical Abstract
Figure 1: A) Deamination of cytosine, dC and C as individual nucleosides or as part of a polynucleotide chain...
Scheme 1: i) Boc2O, DMAP, THF, rt, overnight; ii) aq 5 M NaOH, rt, 3 h, 89% yield over two steps; iii) 3, azo...
Scheme 2: i) NaN3, n-Bu4NHSO4, NaHCO3/CHCl3 (1:1), rt, 20 min, 88% yield; ii) a) H2, Pd/C, CH2Cl2, rt, 3 h; b...
Scheme 3: i) H2, 5% Pd/CaCO3/3% Pb, Et3N, CH2Cl2, rt, 1.5 h, 34% and 21% yield for α- and β-anomer of 18, res...
Figure 2: V0 of A3A mimic-catalysed deamination of 5'-dTTTTCAT in the absence (no inhibitor) and presence of ...