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Search for "chlorinated solvents" in Full Text gives 37 result(s) in Beilstein Journal of Organic Chemistry.
Primary-tertiary diamine-catalyzed Michael addition of ketones to isatylidenemalononitrile derivatives
Beilstein J. Org. Chem. 2014, 10, 929–935, doi:10.3762/bjoc.10.91
- solvents, such as 1,4-dioxane and methyl tert-butyl ether (MTBE), provided Michael adduct 4a in 89% and 90% yield and 89% ee and 87% ee, respectively (Table 1, entries 4 and 5). In toluene, 4a was obtained in 89% yield and 90% ee (Table 1, entry 6). The chlorinated solvents such as dichloromethane
Charge-transfer interaction mediated organogels from 18β-glycyrrhetinic acid appended pyrene
Beilstein J. Org. Chem. 2013, 9, 2877–2885, doi:10.3762/bjoc.9.324
- ]. Besides the mixed solvents, gelation and partial gelation also occurred in ethylene glycol (entry 12, Table 1) and acetonitrile (entry 13, Table 1). In aromatic solvents (entries 14 and 15, Table 1), chlorinated solvents (entries 16 and 17, Table 1) and low molecular weight alcohols (entries 18 and 19
Modulating NHC catalysis with fluorine
Beilstein J. Org. Chem. 2013, 9, 2812–2820, doi:10.3762/bjoc.9.316
- enantioselectivity (Table 1, entries 2–8). Chlorinated solvents such as CH2Cl2 and CDCl3 (Table 1, entries 2 and 3) led to losses in enantioselectivity, whilst THF completely suppressed the reaction (Table 1, entry 4, <1% conversion). Intriguingly, switching from THF to Et2O (Table 1, entry 5) resulted in full
Gold-catalyzed intermolecular coupling of sulfonylacetylene with allyl ethers: [3,3]- and [1,3]-rearrangements
Beilstein J. Org. Chem. 2013, 9, 1724–1729, doi:10.3762/bjoc.9.198
- = di-t-butyl-o-biphenylphosphine, JohnPhos) formed in situ was used as catalyst, the reaction was more efficient in chlorinated solvents rather than polar aprotic or aromatic hydrocarbon solvents (Table 1, entries 1–7). Contrary to the previous [4 + 2] cycloaddition, formal enyne cross metathesis or [2
Coupling of C-nitro-NH-azoles with arylboronic acids. A route to N-aryl-C-nitroazoles
Beilstein J. Org. Chem. 2013, 9, 1517–1525, doi:10.3762/bjoc.9.173
- arylboronic acids and substituted C-nitroazole coupling, applying the conditions described for the Chan–Lam reaction. This involves the use of chlorinated solvents, pyridine as base, and prolonged reaction times to obtain high yields of the product [28][29]. No detailed investigation on the influence of the
Enantioselective reduction of ketoimines promoted by easily available (S)-proline derivatives
Beilstein J. Org. Chem. 2013, 9, 633–640, doi:10.3762/bjoc.9.71
- good yield after 18 hours. Under these conditions a modest to good level of stereoselection were observed; the best results were obtained by running the reaction in chlorinated solvents, such as dichloromethane and chloroform, where enantioselectivity up to 75% was achieved by simply performing the
Asymmetric Brønsted acid-catalyzed aza-Diels–Alder reaction of cyclic C-acylimines with cyclopentadiene
Beilstein J. Org. Chem. 2012, 8, 1819–1824, doi:10.3762/bjoc.8.208
- was used (Table 1, entries 10 and 11). Hence, the chlorinated solvents were replaced by hexane. Interestingly, use of a 1:1 mixture of toluene and hexane afforded the corresponding product without loss of selectivity, but, as anticipated, the reaction time was longer (Table 1, entry 12). Pleasingly
Manganese dioxide mediated one-pot synthesis of methyl 9H-pyrido[3,4-b]indole-1-carboxylate: Concise synthesis of alangiobussinine
Beilstein J. Org. Chem. 2011, 7, 1407–1411, doi:10.3762/bjoc.7.164
- ). Changing the solvent to chloroform showed that chlorinated solvents are compatible in the reaction (Table 1, entry c), and that the low temperature was more detrimental to the process than the nature of the solvent. The process was found to work best when 1,4-dioxane was used as the solvent, with a yield
The arene–alkene photocycloaddition
Beilstein J. Org. Chem. 2011, 7, 525–542, doi:10.3762/bjoc.7.61
- isolated in moderate yield. Anisole photocycloaddition precursors did not afford similar tetracyclic compounds under the same irradiation conditions. However, under slightly acidic conditions (chlorinated solvents or additional p-toluenesulfonic acid) the photocycloaddition to the same compound could be
Thermal rearrangement of tert-butylsulfinamide
Beilstein J. Org. Chem. 2011, 7, 9–12, doi:10.3762/bjoc.7.2
- above room temperature, and in chlorinated solvents they undergo rearrangement to form the more stable N-(tert-butylthio)-tert-butylsulfonamide. Keywords: chlorinated solvents; N-(tert-butylthio)-tert-butylsulfonamide; tert-butylsulfinamide; thermal rearrangement; Introduction Over the past decade, an
- room temperature and in chlorinated solvents. Experimental See Supporting Information File 1 for full experimental data. tert-Butylsulfinamide. N-(tert-butylthio)-tert-butylsulfonamide. ORTEP diagram of 3. Synthesis of acid amide. Chemical synthesis of 3. Synthesis of tert-butylsulfanyl chloride
About the activity and selectivity of less well-known metathesis catalysts during ADMET polymerizations
Beilstein J. Org. Chem. 2010, 6, 1149–1158, doi:10.3762/bjoc.6.131
- activity of the catalyst. Furthermore, Johnson and coworkers reported that during a RCM to make a 9-membered ring, chlorinated solvents, such as 1,2-dichloroethane, inhibited olefin isomerization [25]. Grubbs and collaborators showed that catalytic amounts (10 mol %) of 1,4-benzoquinone (BQ) can prevent
Kinetics and mechanism of vanadium catalysed asymmetric cyanohydrin synthesis in propylene carbonate
Beilstein J. Org. Chem. 2010, 6, 1043–1055, doi:10.3762/bjoc.6.119
- chlorinated solvents, optimally dichloromethane. Recently however, we showed that catalyst 2 could be used in propylene carbonate [53]. Propylene carbonate and other cyclic carbonates are starting to attract significant interest as green solvents [54][55][56][57][58][59][60][61][62][63][64], since they can be
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