Cross-dehydrogenative coupling for the intermolecular C–O bond formation

• Igor B. Krylov,
• Vera A. Vil’ and
• Alexander O. Terent’ev

Beilstein J. Org. Chem. 2015, 11, 92–146, doi:10.3762/bjoc.11.13

• -dehydrogenative C–O coupling reaction are dictated mainly by the nature of the C-reagent. Hence, in the present review the data are classified according to the structures of C-reagents, and, in the second place, according to the type of oxidative systems. Besides the typical cross-dehydrogenative coupling

• ; C–H functionalization; C–O bond formation; cross-dehydrogenative coupling; oxidative cross-coupling; Introduction The development of methods for the cross-dehydrogenative coupling (CDC; or oxidative cross coupling) is an important field of modern organic chemistry. These terms commonly refer to

• . Therefore, the cross-dehydrogenative coupling is a promising approach to the minimization of byproduct formation and the reduction of the number of steps of the organic synthesis [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15]. Studies of the cross-dehydrogenative coupling are not only of practical but

Exploration of C–H and N–H-bond functionalization towards 1-(1,2-diarylindol-3-yl)tetrahydroisoquinolines

• Michael Ghobrial,
• Marko D. Mihovilovic and
• Michael Schnürch

Beilstein J. Org. Chem. 2014, 10, 2186–2199, doi:10.3762/bjoc.10.226

• salt [11]. This synthesis has been streamlined by cross dehydrogenative coupling (CDC) – a powerful method for C–C-bond formation via the C–H bonds of a pro-nucleophile and a pro-electrophile [12][13][14]. A landmark contribution published by Li and co-workers reported the successful introduction of

• wanted to use direct functionalization either via C–H activation or cross dehydrogenative coupling for C–C-bond-forming reactions avoiding the use of two prefunctionalized building blocks. Naturally, C–N-bond formation should proceed via Buchwald–Hartwig coupling. The target molecules can be considered

Iron-catalyzed decarboxylative alkenylation of cycloalkanes with arylvinyl carboxylic acids via a radical process

• Jincan Zhao,
• Hong Fang,
• Jianlin Han and
• Yi Pan

Beilstein J. Org. Chem. 2013, 9, 1718–1723, doi:10.3762/bjoc.9.197

• reactions. Additionally, metal-free methodologies, which use TBHP, PhI(OAc)2, TBAI, I2 or Lewis/Brønsted acids, have also been employed for cross-dehydrogenative coupling reactions [48][49][50][51][52][53][54][55][56][57]. Owing to the general low reactivity of cycloalkane C(sp3)–H bonds, the direct

A³-Coupling catalyzed by robust Au nanoparticles covalently bonded to HS-functionalized cellulose nanocrystalline films

• Jian-Lin Huang,
• Derek G. Gray and
• Chao-Jun Li

Beilstein J. Org. Chem. 2013, 9, 1388–1396, doi:10.3762/bjoc.9.155

• environmental pollution [1][2]. In the past few decades, aqueous-phase organic reactions have achieved great success [3][4][5]. The classic examples include the Grignard-type reactions [6][7], transition-metal catalyzed C–C bond formations [8][9] and cross-dehydrogenative coupling (CDC) reactions [10][11][12