A thermally-induced, tandem [3,3]-sigmatropic rearrangement/[2 + 2] cycloaddition approach to carbocyclic spirooxindoles

• Kay M. Brummond and
• Joshua M. Osbourn

Beilstein J. Org. Chem. 2010, 6, No. 33, doi:10.3762/bjoc.6.33

• spirocyclobutanes that are accessed via alkylation chemistry [5]. Alternatively, more structurally complex spirocyclobutanes have been obtained from homodimerization reactions of allenes or alkenes [6][7]. However, neither of these approaches provides an enabling strategy for accessing the densely functionalized