Development of fluorinated benzils and bisbenzils as room-temperature phosphorescent molecules

• Shigeyuki Yamada,
• Takuya Higashida,
• Yizhou Wang,
• Masato Morita,
• Takuya Hosokai,
• Kaveendra Maduwantha,
• Kaveenga Rasika Koswattage and
• Tsutomu Konno

Beilstein J. Org. Chem. 2020, 16, 1154–1162, doi:10.3762/bjoc.16.102

• Nanocharacterization Facility (ANCF) platform as part of a program of the “Nanotechnology Platform” of the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan.

The reaction of arylmethyl isocyanides and arylmethylamines with xanthate esters: a facile and unexpected synthesis of carbamothioates

• Narasimhamurthy Rajeev,
• Toreshettahally R. Swaroop,
• Ahmad I. Alrawashdeh,
• Shofiur Rahman,
• Abdullah Alodhayb,
• Seegehalli M. Anil,
• Kuppalli R. Kiran,
• Chandra,
• Paris E. Georghiou,
• Kanchugarakoppal S. Rangappa and
• Maralinganadoddi P. Sadashiva

Beilstein J. Org. Chem. 2020, 16, 159–167, doi:10.3762/bjoc.16.18

• , Manasagangothri, Mysuru, Karnataka 570 006, India Department of Chemistry, Memorial University of Newfoundland, St. John’s, Newfoundland and Labrador A1B3X7, Canada Aramco Laboratory for Applied Sensing Research, King Abdullah Institute for Nanotechnology, King Saudi University, Riyadh, Saudi Arabia Surface, and

A combinatorial approach to improving the performance of azoarene photoswitches

• Joaquin Calbo,
• Aditya R. Thawani,
• Rosina S. L. Gibson,
• Andrew J. P. White and
• Matthew J. Fuchter

Beilstein J. Org. Chem. 2019, 15, 2753–2764, doi:10.3762/bjoc.15.266

• including imaging applications [20], photopharmacology [21], supramolecular chemistry [22][23], responsive foams [24], coordination chemistry [25] and DNA nanotechnology [26][27]. Whilst the azopyrazoles have excellent properties for use in a variety of photo-addressable applications, it remains frustrating

A photochemical determination of luminescence efficiency of upconverting nanoparticles

• Baptiste Amouroux,
• Clément Roux,
• Jean-Claude Micheau,
• Fabienne Gauffre and
• Christophe Coudret

Beilstein J. Org. Chem. 2019, 15, 2671–2677, doi:10.3762/bjoc.15.260

• , typically near infrared (NIR), into high energy one thanks to noncoherent photon absorption is called “upconversion”. This phenomenon is exemplified by the lanthanide-based materials [1]. With the rapid developments of nanotechnology, upconverting Ln3+-based nanoparticles (UCNPs) have been reported for

In search of visible-light photoresponsive peptide nucleic acids (PNAs) for reversible control of DNA hybridization

• Lei Zhang,
• Greta Linden and
• Olalla Vázquez

Beilstein J. Org. Chem. 2019, 15, 2500–2508, doi:10.3762/bjoc.15.243

• first compounds here reported, may find applications in different fields such as chemical biology, nanotechnology and materials science. Keywords: azobenzene; hemithioindigo; peptide nucleic acid (PNA); photoswitch; visible-light irradiation; Introduction Light-driven control of oligonucleotide

• from life science such as nanotechnology and materials science. A) Structure of the pioneering azobenzene-modified DNA [16] compared with the photoswitchable PNA structure based on a monomer surrogate. B) Isomerization of the molecular transducers incorporated and studied in this project: 1.: tetra

Nanopatterns of arylene–alkynylene squares on graphite: self-sorting and intercalation

• Tristan J. Keller,
• Joshua Bahr,
• Kristin Gratzfeld,
• Nina Schönfelder,
• Marcin A. Majewski,
• Marcin Stępień,
• Sigurd Höger and
• Stefan-S. Jester

Beilstein J. Org. Chem. 2019, 15, 1848–1855, doi:10.3762/bjoc.15.180

• interface; Introduction Two-dimensional (2D) nanoporous systems on solid surfaces have gained recent interest in nanosciences and nanotechnology. A precise control of the arrangement/periodicity [1] and pore geometries [2] is crucial for potential applications. Beyond nanofabrication [3][4][5], as a top

Recent advances on the transition-metal-catalyzed synthesis of imidazopyridines: an updated coverage

• Gagandeep Kour Reen,
• Ashok Kumar and
• Pratibha Sharma

Beilstein J. Org. Chem. 2019, 15, 1612–1704, doi:10.3762/bjoc.15.165

• copper catalyst dissolved in ionic liquid to four synthetic cycles. Nanotechnology coupled with heterogeneous catalysis has emerged as an efficient field of catalysis for various organic transformations. Inspired from this Bagdi et al. have reported a nano-copper oxide-mediated three-component A3

Insertion of [1.1.1]propellane into aromatic disulfides

• Robin M. Bär,
• Gregor Heinrich,
• Martin Nieger,
• Olaf Fuhr and
• Stefan Bräse

Beilstein J. Org. Chem. 2019, 15, 1172–1180, doi:10.3762/bjoc.15.114

• , Finland Institute of Nanotechnology (INT) and Karlsruhe Nano-Micro Facility (KNMF), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany Institute of Toxicology and Genetics, Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1

Electrophilic oligodeoxynucleotide synthesis using dM-Dmoc for amino protection

• Shahien Shahsavari,
• Dhananjani N. A. M. Eriyagama,
• Bhaskar Halami,
• Vagarshak Begoyan,
• Marina Tanasova,
• Jinsen Chen and
• Shiyue Fang

Beilstein J. Org. Chem. 2019, 15, 1116–1128, doi:10.3762/bjoc.15.108

• instability of the adduct under acidic conditions during ODN synthesis [7]. In recent years, applications of ODNs have extended to emerging areas such as nanotechnology [8][9], antisense drug development [10][11][12], DNA damage and repair [13][14], DNA methylation and demethylation [15][16][17][18], DNA

Homo- and hetero-difunctionalized β-cyclodextrins: Short direct synthesis in gram scale and analysis of regiochemistry

• Gábor Benkovics,
• Mihály Bálint,
• Éva Fenyvesi,
• Erzsébet Varga,
• Szabolcs Béni,
• Konstantina Yannakopoulou and
• Milo Malanga

Beilstein J. Org. Chem. 2019, 15, 710–720, doi:10.3762/bjoc.15.66

• , Hungary Institute of Nanoscience and Nanotechnology National Center for Scientific Research “Demokritos”, Patr. Gregoriou E & 27 Neapoleos str., Aghia Paraskevi Attikis 15341, Greece 10.3762/bjoc.15.66 Abstract The regioselective difunctionalization of cyclodextrins (CDs) leading to derivatives amenable

Application of olefin metathesis in the synthesis of functionalized polyhedral oligomeric silsesquioxanes (POSS) and POSS-containing polymeric materials

• Patrycja Żak and
• Cezary Pietraszuk

Beilstein J. Org. Chem. 2019, 15, 310–332, doi:10.3762/bjoc.15.28

• to 11033 Da and polydispersity index (PDI) = 1.5. Ring-opening metathesis polymerization (ROMP) of POSS-functionalized monomers The chemistry of inorganic–organic hybrid materials has emerged as a fascinating new field of modern nanotechnology. The inclusion of POSS cages into the polymeric material

An overview on recent advances in the synthesis of sulfonated organic materials, sulfonated silica materials, and sulfonated carbon materials and their catalytic applications in chemical processes

• Hashem Sharghi,
• Pezhman Shiri and
• Mahdi Aberi

Beilstein J. Org. Chem. 2018, 14, 2745–2770, doi:10.3762/bjoc.14.253

• considered to replace traditional mineral solid and liquid acids. These catalysts have been well developed and are one of the significant branches in organic chemistry, advanced materials, and nanotechnology. They have some unique properties including stability in air and aqueous environments, ease of

• intermediates is of current interest [54]. 3. Synthetic strategies of SiO2 and functionalized SiO2 containing sulfonic acid groups as a diverse class of catalysts and their uses in organic reactions Nowadays, nanotechnology utilizing substances in the nanometer scale has attracted increasing attention in many

Calixazulenes: azulene-based calixarene analogues – an overview and recent supramolecular complexation studies

• Paris E. Georghiou,
• Shofiur Rahman,
• Abdullah Alodhayb,
• Hidetaka Nishimura,
• Jaehyun Lee,
• Atsushi Wakamiya and
• Lawrence T. Scott

Beilstein J. Org. Chem. 2018, 14, 2488–2494, doi:10.3762/bjoc.14.225

• Institute for Nanotechnology, King Saud University, Riyadh, Saudi Arabia Department of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Saudi Arabia Institute for Chemical Research, Kyoto University, Uji, Japan Merkert Chemistry Center, Boston College, Chestnut Hill, MA, 02467

Nucleoside macrocycles formed by intramolecular click reaction: efficient cyclization of pyrimidine nucleosides decorated with 5'-azido residues and 5-octadiynyl side chains

• Jiang Liu,
• Peter Leonard,
• Sebastian L. Müller,
• Constantin Daniliuc and
• Frank Seela

Beilstein J. Org. Chem. 2018, 14, 2404–2410, doi:10.3762/bjoc.14.217

• Laboratory of Bioorganic Chemistry and Chemical Biology, Center for Nanotechnology, Heisenbergstrasse 11, 48149 Münster, Germany Laboratorium für Organische und Bioorganische Chemie, Institut für Chemie neuer Materialien, Universität Osnabrück, Barbarastrasse 7, 49069 Osnabrück, Germany Institut für

Are dispersion corrections accurate outside equilibrium? A case study on benzene

• Tim Gould,
• Erin R. Johnson and
• Sherif Abdulkader Tawfik

Beilstein J. Org. Chem. 2018, 14, 1181–1191, doi:10.3762/bjoc.14.99

• Tim Gould Erin R. Johnson Sherif Abdulkader Tawfik Queensland Micro- and Nanotechnology Centre, Griffith University, Nathan, Queensland 4111, Australia Department of Chemistry, Dalhousie University, Halifax, Nova Scotia, B3H 4R2, Canada School of Mathematical and Physical Sciences, University of

Recent applications of click chemistry for the functionalization of gold nanoparticles and their conversion to glyco-gold nanoparticles

• Vivek Poonthiyil,
• Thisbe K. Lindhorst,
• Vladimir B. Golovko and
• Antony J. Fairbanks

Beilstein J. Org. Chem. 2018, 14, 11–24, doi:10.3762/bjoc.14.2

• Zealand The MacDiarmid Institute for Advanced Materials and Nanotechnology, Wellington, 6140, New Zealand Biomolecular Interaction Centre, University of Canterbury, Private Bag 4800, Christchurch 8140, New Zealand 10.3762/bjoc.14.2 Abstract Glycoscience, despite its myriad of challenges, promises to

Solid-state mechanochemical ω-functionalization of poly(ethylene glycol)

• Michael Y. Malca,
• Pierre-Olivier Ferko,
• Tomislav Friščić and
• Audrey Moores

Beilstein J. Org. Chem. 2017, 13, 1963–1968, doi:10.3762/bjoc.13.191

• manufacturing, drug development and nanotechnology. PEG derivatives are being increasingly used to covalently modify small molecule and peptide drugs, as well as bioactive nanomaterials in order to improve solubility in biological serum, reduce immunogenicity, and enhance pharmacokinetic profiles. Herein we

Molecular recognition of N-acetyltryptophan enantiomers by β-cyclodextrin

• Spyros D. Chatziefthimiou,
• Mario Inclán,
• Petros Giastas,
• Athanasios Papakyriakou,
• Konstantina Yannakopoulou and
• Irene M. Mavridis

Beilstein J. Org. Chem. 2017, 13, 1572–1582, doi:10.3762/bjoc.13.157

• Spyros D. Chatziefthimiou Mario Inclan Petros Giastas Athanasios Papakyriakou Konstantina Yannakopoulou Irene M. Mavridis Institute of Nanoscience & Nanotechnology, National Center for Scientific Research “Demokritos”, Patriarchou Gregoriou E’ & Neapoleos 27, 15310 Aghia Paraskevi Attikis, Greece

Biomimetic molecular design tools that learn, evolve, and adapt

• David A Winkler

Beilstein J. Org. Chem. 2017, 13, 1288–1302, doi:10.3762/bjoc.13.125

• than the self-assembled systems that have been a major feature of contemporary nanotechnology [8][9][10]. Computational adaptive, evolving, self-learning design and optimization methods are approaching an era of very rapid growth, and their impact is already being seen as potentially disruptive. Their

Correction: Fluorescent carbon dots from mono- and polysaccharides: synthesis, properties and applications

• Stephen Hill and
• M. Carmen Galan

Beilstein J. Org. Chem. 2017, 13, 1136–1138, doi:10.3762/bjoc.13.112

• Stephen Hill M. Carmen Galan School of Chemistry, University of Bristol, Cantock’s Close, Bristol BS8 1TS, UK 10.3762/bjoc.13.112 Keywords: fluorescent carbon dots; monosaccharides; nanomaterials; nanotechnology applications; polysaccharides; Our original publication showns some errors in the

Glyco-gold nanoparticles: synthesis and applications

• Federica Compostella,
• Olimpia Pitirollo,
• Alessandro Silvestri and
• Laura Polito

Beilstein J. Org. Chem. 2017, 13, 1008–1021, doi:10.3762/bjoc.13.100

• , Nanotechnology Lab., Via G. Fantoli 16/15, 20138 Milan, Italy 10.3762/bjoc.13.100 Abstract Glyco-gold nanoparticles combine in a single entity the peculiar properties of gold nanoparticles with the biological activity of carbohydrates. The result is an exciting nanosystem, able to mimic the natural multivalent

• , gold can be easily and covalently decorated on its surface by exploiting the strong soft–soft interaction between a Au atom and sulfur [8]. Therefore, glyco-gold nanoparticles (GAuNPs) represent a smart, multimodal and versatile nanoplatform to develop carbohydrate-based nanotechnology and nanomedicine

• carriers, to target antigens to DCs via lectins, a well-known strategy explored in immunotherapy. GAuNPs in vaccine development AuNPs engineering is offering significant contribution to immunology also in vaccine development. The repetitive antigen display is the key point related to this nanotechnology

Fluorescent carbon dots from mono- and polysaccharides: synthesis, properties and applications

• Stephen Hill and
• M. Carmen Galan

Beilstein J. Org. Chem. 2017, 13, 675–693, doi:10.3762/bjoc.13.67

• challenges. Keywords: fluorescent carbon dots; monosaccharides; nanomaterials; nanotechnology applications; polysaccharides; Introduction Nanotechnology applied to biological and biomedical problems has seen an explosion of research in recent years [1]. Functional nanomaterials that can carry biologically

A versatile route to polythiophenes with functional pendant groups using alkyne chemistry

• Xiao Huang,
• Li Yang,
• Rikard Emanuelsson,
• Jonas Bergquist,
• Maria Strømme,
• Martin Sjödin and
• Adolf Gogoll

Beilstein J. Org. Chem. 2016, 12, 2682–2688, doi:10.3762/bjoc.12.265

• Xiao Huang Li Yang Rikard Emanuelsson Jonas Bergquist Maria Stromme Martin Sjodin Adolf Gogoll Department of Chemistry - BMC, Uppsala University, Box 576, 751 23 Uppsala, Sweden Nanotechnology and Functional Materials, Department of Engineering Sciences, Uppsala University, Box 534, 751 21 Uppsala

Enzymatic synthesis and phosphorolysis of 4(2)-thioxo- and 6(5)-azapyrimidine nucleosides by E. coli nucleoside phosphorylases

• Vladimir A. Stepchenko,
• Anatoly I. Miroshnikov,
• Frank Seela and
• Igor A. Mikhailopulo

Beilstein J. Org. Chem. 2016, 12, 2588–2601, doi:10.3762/bjoc.12.254

• /10, 117997 GSP, Moscow B-437, Russia Laboratory of Bioorganic Chemistry and Chemical Biology, Center for Nanotechnology, Heisenbergstraße 11, D-48149 Münster, Germany 10.3762/bjoc.12.254 Abstract The trans-2-deoxyribosylation of 4-thiouracil (4SUra) and 2-thiouracil (2SUra), as well as 6-azauracil

A direct method for the N-tetraalkylation of azamacrocycles

• Andrew J. Counsell,
• Angus T. Jones,
• Matthew H. Todd and
• Peter J. Rutledge

Beilstein J. Org. Chem. 2016, 12, 2457–2461, doi:10.3762/bjoc.12.239

• be optimised alongside mixing performance [46], and in nanotechnology, where shaking can be used to modulate aggregation so as to favour particular nanostructures [47][48]. Otto and co-workers have investigated the influence of mechanical forces on reactivity in the context of self-replication by