Self-assembled monolayers of shape-persistent macrocycles on graphite: interior design and conformational polymorphism

• Joscha Vollmeyer,
• Friederike Eberhagen,
• Sigurd Höger and
• Stefan-S. Jester

Beilstein J. Org. Chem. 2014, 10, 2774–2782, doi:10.3762/bjoc.10.294

• intraannular strands on the supramolecular assembly in one and two dimensions, a strategy to attach functional units that point away from the surface to the third dimension in a pillar-like fashion, as well as the attachment of groups that selectively bind additional guest molecules that do not self-assemble

Specific DNA duplex formation at an artificial lipid bilayer: fluorescence microscopy after Sybr Green I staining

• Emma Werz and
• Helmut Rosemeyer

Beilstein J. Org. Chem. 2014, 10, 2307–2321, doi:10.3762/bjoc.10.240

• should exist which can only be shielded by solvation of the lipid head groups and of the nucleic acid phosphodiester groups as well as by the metal cations of the surrounding buffer. The supramolecular assembly of all reaction partners might look like as shown in Figure 9. From this figure it can be

End group functionalization of poly(ethylene glycol) with phenolphthalein: towards star-shaped polymers based on supramolecular interactions

• Carolin Fleischmann,
• Hendrik Wöhlk and
• Helmut Ritter

Beilstein J. Org. Chem. 2014, 10, 2263–2269, doi:10.3762/bjoc.10.235

• spectroscopy and even the naked eye. Keywords: cyclodextrin; phenolphthalein; poly(ethylene glycol); supramolecular assembly; UV–vis spectroscopy; Introduction Over the past decades, polymers with well-defined and complex architectures gained increasing attention due to a broad variety of applications

Postsynthetic functionalization of glycodendrons at the focal point

• Thisbe K. Lindhorst and
• Katharina Elsner

Beilstein J. Org. Chem. 2014, 10, 1482–1487, doi:10.3762/bjoc.10.152

• glycoconjugate to a scaffold or surface, respectively, after suitable postsynthetic modification at the focal point of the molecule. Moreover, such an approach opens the door to a number of intriguing applications of multivalent glycoconjugates such as incorporation into a supramolecular assembly, for example

A peptidic hydrogel that may behave as a “Trojan Horse”

• Nicola Castellucci,
• Giorgio Sartor,
• Natalia Calonghi,
• Carola Parolin,
• Giuseppe Falini and
• Claudia Tomasini

Beilstein J. Org. Chem. 2013, 9, 417–424, doi:10.3762/bjoc.9.44

• direction, while that at 0.54 nm is along the meridional direction. These low-angle periodicities could be associated with different diffraction orders of a periodic distance of 2.5 nm. This observation, in agreement with a rough estimation of the dimensions of molecule 1, may suggest a supramolecular

• assembly of molecules 1 to form the fibrous structures. Moreover, XRD data and SEM observation show that in the xerogel the fibers align preferentially parallel to the film surface and may suggest that in the fiber the molecules are organized in layers (0.54 nm thick) and that they have their long axis

Cyclodextrin-based nanosponges as drug carriers

• Francesco Trotta,
• Marco Zanetti and
• Roberta Cavalli

Beilstein J. Org. Chem. 2012, 8, 2091–2099, doi:10.3762/bjoc.8.235

• ; cross-linked polymers; cyclodextrin; drug delivery; nanosponges; Review Recent advances in nanotechnology demonstrate the increased attention that is now being paid to the supramolecular assembly of simple components for therapeutic and diagnostic purposes. The design of new biomaterials based on

Restructuring polymers via nanoconfinement and subsequent release

• Alan E. Tonelli

Beilstein J. Org. Chem. 2012, 8, 1318–1332, doi:10.3762/bjoc.8.151

• regarding the conformations, mobilities and supramolecular assembly of polymers can be obtained by observing and modeling both the formation of polymer ICs [47][73][76] and the behaviors of their included, highly extended, and isolated guest polymer chains [73][76]. Finally, we have also tried to indicate

Enantioselective supramolecular devices in the gas phase. Resorcin[4]arene as a model system

• Caterina Fraschetti,
• Matthias C. Letzel,
• Antonello Filippi,
• Maurizio Speranza and
• Jochen Mattay

Beilstein J. Org. Chem. 2012, 8, 539–550, doi:10.3762/bjoc.8.62

• complex of the guest 3 is more reactive than those of 1, with the only exception of the heterochiral [I∙H∙G]+ (G = 1, 3). This enantioselectivity trend was ascribed to structural and steric factors, given the similar basicity of 1–3 [45][46][47]. The access of the amine B to the supramolecular assembly

Self-assembly and semiconductivity of an oligothiophene supergelator

• Pampa Pratihar,
• Suhrit Ghosh,
• Vladimir Stepanenko,
• Sameer Patwardhan,
• Ferdinand C. Grozema,
• Laurens D. A. Siebbeles and
• Frank Würthner

Beilstein J. Org. Chem. 2010, 6, 1070–1078, doi:10.3762/bjoc.6.122

• thermal stability of the supramolecular assembly of T1. A repeat measurement of mobility at 20 °C after the sample was annealed revealed a slightly higher value (4.2 × 10−3 cm2 V−1 s−1), indicating an improvement of the supramolecular order in the material on annealing. It is interesting to note that the

Towards racemizable chiral organogelators

• Jian Bin Lin,
• Debarshi Dasgupta,
• Seda Cantekin and
• Albertus P. H. J. Schenning

Beilstein J. Org. Chem. 2010, 6, 960–965, doi:10.3762/bjoc.6.107

• advanced materials and constrained media for chiral synthesis and separation [3][4][5]. The development of systems where the chiral supramolecular assembly responds to specific triggers, should facilitate the design of smart functional materials in which subtle molecular-scale changes have an impact on the

The subtle balance of weak supramolecular interactions: The hierarchy of halogen and hydrogen bonds in haloanilinium and halopyridinium salts

• Kari Raatikainen,
• Massimo Cametti and
• Kari Rissanen

Beilstein J. Org. Chem. 2010, 6, No. 4, doi:10.3762/bjoc.6.4

• chemistry and crystal engineering is to identify the hierarchies of non-covalent interactions in order to develop efficient synthetic strategies for attaining advanced supramolecular systems [1]. The structure of a supramolecular assembly in crystalline solids generally results from the balance of all

Versatile supramolecular reactivity of zinc-tetra(4-pyridyl)porphyrin in crystalline solids: Polymeric grids with zinc dichloride and hydrogen-bonded networks with mellitic acid

• Sophia Lipstman and
• Israel Goldberg

Beilstein J. Org. Chem. 2009, 5, No. 77, doi:10.3762/bjoc.5.77

• (at positions 3 and 6 of the central benzene ring) did not interact with Zn(EtOH)TPyP, thus mimicking effectively the functionality of B4CA. The supramolecular assembly that formed in this case is depicted in Figure 2. Crystal data for II: C40H24N8Zn·C2H5OH·C12H6O12 (crystallization solvent, X

• building blocks of the supramolecular assembly in I and II. Supporting Information Supporting information features X-ray data for compounds I and II. Supporting Information File 125: X-ray data for compound I. Supporting Information File 126: X-ray data for compound II. Acknowledgement This research was

Hydrogen bonding patterns in the cocrystals of 5-nitrouracil with several donor and acceptor molecules

• Reji Thomas,
• R. Srinivasa Gopalan,
• G. U. Kulkarni and
• C. N. R. Rao

Beilstein J. Org. Chem. 2005, 1, No. 15, doi:10.1186/1860-5397-1-15

• Figure 9. This is yet another example of a supramolecular assembly hosting acyclic pentamer clusters of water. [31][32][33][34][35][36] The tetrahedral pentameric unit corresponds exactly to that described by Walrafen,[37][38] involving a central H2O molecule where the two hydrogen donors of the central

• 3-aminopyridine: Stacks of molecular tapes arranged in alternating parallel and perpendicular orientations. Cocrystal of I and DABCO: A view along the diagonal of the ab plane showing the supramolecular assembly. Inset shows some important hydrogen bonding patterns. (a) Tetrahedral pentamers of