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Search for "amide group" in Full Text gives 92 result(s) in Beilstein Journal of Organic Chemistry.

Fifty years of oxacalix[3]arenes: A review

  • Kevin Cottet,
  • Paula M. Marcos and
  • Peter J. Cragg

Beilstein J. Org. Chem. 2012, 8, 201–226, doi:10.3762/bjoc.8.22

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  • product (Figure 23) [69]. The structure revealed that a [HgCl2]2 fragment bridged between two macrocycles through coordination to one amide group of each. The cations were thus exo to the macrocyclic cavity and represented the first example in which a cation was not bound within the annulus. Marcos
  • also shows that ketone 24 is a weak extracting agent, with a slight preference for Ag+. This is in agreement with the higher basicity of the carbonyl oxygen in the amide group compared with the ketone group. 4.2.4 Lanthanides: Marcos investigated the lanthanide extraction by both 17a [70] and 24 [39
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Published 07 Feb 2012

Synthetic approaches to multifunctional indenes

  • Neus Mesquida,
  • Sara López-Pérez,
  • Immaculada Dinarès and
  • Ermitas Alcalde

Beilstein J. Org. Chem. 2011, 7, 1739–1744, doi:10.3762/bjoc.7.204

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  • %. Compound 7 was then conveniently transformed to the corresponding acetamide 8. The reduction of the amide group with AlH3·NMe2Et was the critical step for the preparation of the key inden-5-amine 9 due to the particularly troublesome isolation process [18]. Thus, a different synthetic option was examined
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Published 29 Dec 2011

Access to pyrrolo-pyridines by gold-catalyzed hydroarylation of pyrroles tethered to terminal alkynes

  • Elena Borsini,
  • Gianluigi Broggini,
  • Andrea Fasana,
  • Chiara Baldassarri,
  • Angelo M. Manzo and
  • Alcide D. Perboni

Beilstein J. Org. Chem. 2011, 7, 1468–1474, doi:10.3762/bjoc.7.170

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  • intramolecular hydroarylation gave 6-exo-dig or 6-endo-dig processes, depending on the substitution of the alkyne. In both cases, products arising from a direct reaction as well as products involving a 1,2-shift of the amide group were obtained, their ratio being influenced by the polarity of the solvent. The
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Published 26 Oct 2011

NMR studies of anion-induced conformational changes in diindolylureas and diindolylthioureas

  • Damjan Makuc,
  • Jennifer R. Hiscock,
  • Mark E. Light,
  • Philip A. Gale and
  • Janez Plavec

Beilstein J. Org. Chem. 2011, 7, 1205–1214, doi:10.3762/bjoc.7.140

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  • involved in hydrogen-bonding interactions with the bound anionic guest, whilst the amide group interacted only weakly with the bound anion. These observations led to the design of diindolylureas and diindolylthioureas [36][37][38]. These compounds have remarkably high affinities for oxo-anions such as
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Published 02 Sep 2011

Fine-tuning alkyne cycloadditions: Insights into photochemistry responsible for the double-strand DNA cleavage via structural perturbations in diaryl alkyne conjugates

  • Wang-Yong Yang,
  • Samantha A. Marrone,
  • Nalisha Minors,
  • Diego A. R. Zorio and
  • Igor V. Alabugin

Beilstein J. Org. Chem. 2011, 7, 813–823, doi:10.3762/bjoc.7.93

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  • higher probability of intercepting the reactive excited state via reaction with a π-system. The photochemical reactivity for the o-substituted acetylene 5 was drastically changed (Scheme 5). In this case, photoexcitation leads to the formation of an oxygen–carbon bond between the amide group and the
  • . A similar trend has been previously observed for the lifetimes of m-substituted enediynes [63]. The absorption spectra of all four acetylenes are shown in Figure 6. The core Ph-TFP-acetylene (Ph-TFP) chromophore without the amide group has no significant absorption at >320 nm. The lowest absorptions
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Published 16 Jun 2011

A new fluorescent chemosensor for fluoride anion based on a pyrrole–isoxazole derivative

  • Zhipei Yang,
  • Kai Zhang,
  • Fangbin Gong,
  • Shayu Li,
  • Jun Chen,
  • Jin Shi Ma,
  • Lyubov N. Sobenina,
  • Albina I. Mikhaleva,
  • Guoqiang Yang and
  • Boris A. Trofimov

Beilstein J. Org. Chem. 2011, 7, 46–52, doi:10.3762/bjoc.7.8

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  • moieties which avoids the problem of multi-anion sensitivity. The common anion recognition moieties, i.e., a pyrrole NH and an amide group, present in the structure behave as proton donors. Isoxazoles and their derivatives are important intermediates in preparation of many natural products and related
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Published 12 Jan 2011

Towards racemizable chiral organogelators

  • Jian Bin Lin,
  • Debarshi Dasgupta,
  • Seda Cantekin and
  • Albertus P. H. J. Schenning

Beilstein J. Org. Chem. 2010, 6, 960–965, doi:10.3762/bjoc.6.107

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  • ; d) the surface morphology of the dried gel obtained from R-3 in octane (15 mM) observed by FESEM. a) Concentration-dependent 1H NMR spectra of R-3 in cyclohexane-d12 and b) the shift of N–H signal of amide group versus concentration. The evolution of ln(ee × 100) for the racemization of R-3 (1 mM
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Published 06 Oct 2010

Pyridinium based amphiphilic hydrogelators as potential antibacterial agents

  • Sayanti Brahmachari,
  • Sisir Debnath,
  • Sounak Dutta and
  • Prasanta Kumar Das

Beilstein J. Org. Chem. 2010, 6, 859–868, doi:10.3762/bjoc.6.101

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  • existence of a non-hydrogen bonded amide group. Hydrogen bond formation is accompanied by a decrease in the bond order and hence the observed shift in the carbonyl stretching frequency to a lower value underlines the participation of intermolecular H-bonding in the gel state [37]. In addition, the N–H
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Published 21 Sep 2010

Novel tetracyclic structures from the synthesis of thiolactone-isatin hybrids

  • Renate Hazel Hans,
  • Hong Su and
  • Kelly Chibale

Beilstein J. Org. Chem. 2010, 6, No. 78, doi:10.3762/bjoc.6.78

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  • , involves an in situ deprotonation at C-5 of the thiolactone ring system by the relatively basic potassium salt of 5. This is followed by the regioselective, intramolecular addition of the nucleophile to the ketonic carbonyl facilitated by (i) the strong electrophilicity of the α-keto amide group of the
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Published 19 Jul 2010

RAFT polymers for protein recognition

  • Alan F. Tominey,
  • Julia Liese,
  • Sun Wei,
  • Klaus Kowski,
  • Thomas Schrader and
  • Arno Kraft

Beilstein J. Org. Chem. 2010, 6, No. 66, doi:10.3762/bjoc.6.66

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  • polymers which are water-soluble at room temperature and even allow thermoprecipitation with a bound protein guest. NIPAM-based polymers are also reminiscent of peptides since both contain an amide group in the repeat unit. RAFT makes use of a chain transfer agent (CTA) for which we selected the water
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Published 17 Jun 2010

Molecular recognition of organic ammonium ions in solution using synthetic receptors

  • Andreas Späth and
  • Burkhard König

Beilstein J. Org. Chem. 2010, 6, No. 32, doi:10.3762/bjoc.6.32

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Published 06 Apr 2010

(Pseudo)amide-linked oligosaccharide mimetics: molecular recognition and supramolecular properties

  • José L. Jiménez Blanco,
  • Fernando Ortega-Caballero,
  • Carmen Ortiz Mellet and
  • José M. García Fernández

Beilstein J. Org. Chem. 2010, 6, No. 20, doi:10.3762/bjoc.6.20

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  • : carbopeptoids The replacement of the glycosidic oxygen atom by an amide group leads to amide-linked sugars (Figure 1), which are synthesised by the sequential coupling of SAAs to form a class of compounds commonly referred to as carbopeptoids. The use of the amide functional group to connect sugar building
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Published 22 Feb 2010

Synthesis and binding studies of two new macrocyclic receptors for the stereoselective recognition of dipeptides

  • Ana Maria Castilla,
  • M. Morgan Conn and
  • Pablo Ballester

Beilstein J. Org. Chem. 2010, 6, No. 5, doi:10.3762/bjoc.6.5

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  • receptors, we studied their dimerization behavior in chloroform solution. Using the same methodology described above for the receptors, we calculated the dimerization constants of all guest molecules. The values obtained are summarized in Table 2. With an additional amide group with respect to diamides, the
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Published 19 Jan 2010

Self-association of an indole based guanidinium-carboxylate-zwitterion: formation of stable dimers in solution and the solid state

  • Carolin Rether,
  • Wilhelm Sicking,
  • Roland Boese and
  • Carsten Schmuck

Beilstein J. Org. Chem. 2010, 6, No. 3, doi:10.3762/bjoc.6.3

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  • occupied by the carbonyl oxygen which forms an H-bond to the guanidinium moiety and thus actually helps to keep the molecule planar. This amide group in 1 is replaced by the aromatic benzene ring in 2, thereby replacing an attractive H-bond with a repulsive steric interaction. This twisted, non-planar
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Published 14 Jan 2010

An expedient and new synthesis of pyrrolo[1,2-b]pyridazine derivatives

  • Rajeshwar Reddy Sagyam,
  • Ravinder Buchikonda,
  • Jaya Prakash Pitta,
  • Himabindu Vurimidi,
  • Pratap Reddy Padi and
  • Mahesh Reddy Ghanta

Beilstein J. Org. Chem. 2009, 5, No. 66, doi:10.3762/bjoc.5.66

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  • ethyl alcohol to provide alkenyl imine 9, which was characterized on the basis of its mass, 1H and 13C NMR, DEPT, and IR spectral data. Compound 9 was heated in toluene in the presence of p-TSA for 10–12 h and the resulting compound was found to be identical to product 6a. Hydrolysis of the amide group
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Published 17 Nov 2009

The tert- amino effect in heterocyclic chemistry: Synthesis of new fused pyrazolinoquinolizine and 1,4-oxazinopyrazoline derivatives

  • Dipak Prajapati and
  • Kalyan Jyoti Borah

Beilstein J. Org. Chem. 2007, 3, No. 43, doi:10.1186/1860-5397-3-43

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  • = 8.6 Hz). The mass spectrum revealed a strong molecular ion peak at 335 (M+). It is to be noted that in the end product 6a one nitrile group is reduced to the corresponding amide group. But it is not yet clear why only one nitrile group is reduced and the other remains intact under the reaction
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Published 12 Dec 2007

Colchitaxel, a coupled compound made from microtubule inhibitors colchicine and paclitaxel

  • Karunananda Bombuwala,
  • Thomas Kinstle,
  • Vladimir Popik,
  • Sonal O. Uppal,
  • James B. Olesen,
  • Jose Viña and
  • Carol A. Heckman

Beilstein J. Org. Chem. 2006, 2, No. 13, doi:10.1186/1860-5397-2-13

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  • paclitaxel binding to tubulin. This group needed to be protected during derivatization. Since acid hydrolysis of the acetamide group in (2) also results in a loss of the methyl group on the adjacent tropolone ring [36], the method of Lebeau and coworkers was used to transform the amide group into the
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Published 30 Jun 2006
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