Synthesis of divalent ligands of β-thio- and β-N-galactopyranosides and related lactosides and their evaluation as substrates and inhibitors of Trypanosoma cruzi trans-sialidase

• María Emilia Cano,
• Rosalía Agusti,
• Alejandro J. Cagnoni,
• María Florencia Tesoriero,
• José Kovensky,
• María Laura Uhrig and
• Rosa M. de Lederkremer

Beilstein J. Org. Chem. 2014, 10, 3073–3086, doi:10.3762/bjoc.10.324

• Buenos Aires, Argentina, Fax: (+) 541145763346 Laboratoire de Glycochimie, des Antimicrobiens et des Agroressources (LG2A)-CNRS FRE 3517, Université de Picardie Jules Verne, 33 rue Saint Leu, 80039 Amiens Cedex, France 10.3762/bjoc.10.324 Abstract In this work we describe the synthesis of mono- and

Palladium-catalyzed 2,5-diheteroarylation of 2,5-dibromothiophene derivatives

• Fatma Belkessam,
• Aidene Mohand,
• Jean-François Soulé,
• Abdelhamid Elias and
• Henri Doucet

Beilstein J. Org. Chem. 2014, 10, 2912–2919, doi:10.3762/bjoc.10.309

• Fatma Belkessam Aidene Mohand Jean-Francois Soule Abdelhamid Elias Henri Doucet Institut des Sciences Chimiques de Rennes, UMR 6226 CNRS-Université de Rennes, "Organométalliques: Matériaux et Catalyse", Campus de Beaulieu, 35042 Rennes, France, Tel.: 00-33-2-23-23-63-84, Fax 00-33-2-23-23-69-39

Synthesis and characterization of a new photoinduced switchable β-cyclodextrin dimer

• Florian Hamon,
• Claire Blaszkiewicz,
• Marie Buchotte,
• Estelle Banaszak-Léonard,
• Hervé Bricout,
• Sébastien Tilloy,
• Eric Monflier,
• Christine Cézard,
• Laurent Bouteiller,
• Christophe Len and
• Florence Djedaini-Pilard

Beilstein J. Org. Chem. 2014, 10, 2874–2885, doi:10.3762/bjoc.10.304

• Université Paris 06, CNRS, UMR 8232, IPCM, Chimie des Polymères, F-75005, Paris, France CNRS, UMR 8232, IPCM, Chimie des Polymères, F-75005, Paris, France 10.3762/bjoc.10.304 Abstract This paper reports an efficient preparation of bridged bis-β-CD AZO-CDim 1 bearing azobenzene as a linker and exhibiting

Cyclodextrin-grafted polymers functionalized with phosphanes: a new tool for aqueous organometallic catalysis

• Jonathan Potier,
• Stéphane Menuel,
• David Mathiron,
• Véronique Bonnet,
• Frédéric Hapiot and
• Eric Monflier

Beilstein J. Org. Chem. 2014, 10, 2642–2648, doi:10.3762/bjoc.10.276

• Jonathan Potier Stephane Menuel David Mathiron Veronique Bonnet Frederic Hapiot Eric Monflier Université Lille Nord de France, CNRS UMR 8181, Unité de Catalyse et de Chimie du Solide, UCCS Artois, Faculté Jean Perrin, rue Jean Souvraz, SP18, 62307 Lens Cédex, France Laboratoire des Glucides FRE

Encapsulation of biocides by cyclodextrins: toward synergistic effects against pathogens

• Véronique Nardello-Rataj and
• Loïc Leclercq

Beilstein J. Org. Chem. 2014, 10, 2603–2622, doi:10.3762/bjoc.10.273

A small azide-modified thiazole-based reporter molecule for fluorescence and mass spectrometric detection

• Stefanie Wolfram,
• Hendryk Würfel,
• Stefanie H. Habenicht,
• Christine Lembke,
• Phillipp Richter,
• Eckhard Birckner,
• Rainer Beckert and
• Georg Pohnert

Beilstein J. Org. Chem. 2014, 10, 2470–2479, doi:10.3762/bjoc.10.258

• funding. This work was further supported by a scholarship from the German National Academic Foundation (Studienstiftung des Deutschen Volkes) to S.W. Erika Kielmann is acknowledged for measuring quantum yields. Natalie Wielsch, Yvonne Hupfer and Aleš Svatoš are acknowledged for technical support and

Reversibly locked thionucleobase pairs in DNA to study base flipping enzymes

• Christine Beuck and
• Elmar Weinhold

Beilstein J. Org. Chem. 2014, 10, 2293–2306, doi:10.3762/bjoc.10.239

• . Acknowledgements We thank Kerstin Glensk for the DTT-free preparation of M.TaqI and Silke Harms for preparation of duplex 1G6S-Et-S4U2. C.B. thanks the Studienstiftung des Deutschen Volkes for a Ph.D. fellowship.

The effect of permodified cyclodextrins encapsulation on the photophysical properties of a polyfluorene with randomly distributed electron-donor and rotaxane electron-acceptor units

• Aurica Farcas,
• Ana-Maria Resmerita,
• Pierre-Henri Aubert,
• Flavian Farcas,
• Iuliana Stoica and
• Anton Airinei

Beilstein J. Org. Chem. 2014, 10, 2145–2156, doi:10.3762/bjoc.10.222

• Aurica Farcas Ana-Maria Resmerita Pierre-Henri Aubert Flavian Farcas Iuliana Stoica Anton Airinei Inorganic Polymers, ‘‘Petru Poni’’ Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley, 700487 Iasi, Romania Laboratoire de Physicochimie des Polymères et des Interfaces (EA 2528

• ), Institut des Matériaux, Université de Cergy-Pontoise, F-95031 Cergy-Pontoise Cedex, France “Gh. Asachi” Technical University, 61–63 Mangeron Blvd, 700050 Iasi, Romania 10.3762/bjoc.10.222 Abstract We report on the synthesis as well as the optical, electrochemical and morphological properties of two

Expeditive synthesis of trithiotriazine-cored glycoclusters and inhibition of Pseudomonas aeruginosa biofilm formation

• Meriem Smadhi,
• Sophie de Bentzmann,
• Anne Imberty,
• Marc Gingras,
• Raoudha Abderrahim and
• Peter G. Goekjian

Beilstein J. Org. Chem. 2014, 10, 1981–1990, doi:10.3762/bjoc.10.206

• : +33-4-72448109; Tel: +33-4-72448183 Université de Carthage, Faculté des sciences Bizerte, Tunisie Laboratoire d'Ingénierie des Systèmes Macromoléculaires, Institut de Biologie Structurale et Microbiologie, CNRS-Aix Marseille University, UMR7255, 31 Chemin Joseph Aiguier, 13402 Marseille Cedex 20

Selective allylic hydroxylation of acyclic terpenoids by CYP154E1 from Thermobifida fusca YX

• Anna M. Bogazkaya,
• Clemens J. von Bühler,
• Sebastian Kriening,
• Alexandrine Busch,
• Alexander Seifert,
• Jürgen Pleiss,
• Sabine Laschat and
• Vlada B. Urlacher

Beilstein J. Org. Chem. 2014, 10, 1347–1353, doi:10.3762/bjoc.10.137

• : Experimental and analytical data. Acknowledgements Generous financial support by the Ministerium für Wissenschaft, Forschung und Kunst des Landes Baden-Württemberg, the Deutsche Forschungsgemeinschaft (SFB 706) and the Fonds der Chemischen Industrie is gratefully acknowledged.

cis–trans Isomerization of silybins A and B

• Michaela Novotná,
• Radek Gažák,
• David Biedermann,
• Florent Di Meo,
• Petr Marhol,
• Marek Kuzma,
• Lucie Bednárová,
• Kateřina Fuksová,
• Patrick Trouillas and
• Vladimír Křen

Beilstein J. Org. Chem. 2014, 10, 1047–1063, doi:10.3762/bjoc.10.105

• of Organic Chemistry and Biochemistry, v.v.i. AS CR, Flemingovo náměstí 2, Prague 6, CZ-16610, Czech Republic Department of Physical Chemistry, University of Olomouc, tř. 17. listopadu 12, CZ-77146 Olomouc, Czech Republic Laboratoire de Chimie des Matériaux Nouveaux, Université de Mons, Place du Parc

Metal and metal-free photocatalysts: mechanistic approach and application as photoinitiators of photopolymerization

• Jacques Lalevée,
• Sofia Telitel,
• Pu Xiao,
• Marc Lepeltier,
• Frédéric Dumur,
• Fabrice Morlet-Savary,
• Didier Gigmes and
• Jean-Pierre Fouassier

Beilstein J. Org. Chem. 2014, 10, 863–876, doi:10.3762/bjoc.10.83

• Jacques Lalevee Sofia Telitel Pu Xiao Marc Lepeltier Frederic Dumur Fabrice Morlet-Savary Didier Gigmes Jean-Pierre Fouassier Institut de Science des Matériaux de Mulhouse IS2M – UMR CNRS 7361 –UHA; 15 rue Jean Starcky, 68057 Mulhouse Cedex, France Institut Lavoisier de Versailles, UMR 8180 CNRS

• , Université de Versailles Saint-Quentin en Yvelines, 45 avenue des Etats-Unis, 78035 Versailles Cedex, France Aix-Marseille Université, CNRS, Institut de Chimie Radicalaire, UMR 7273, F-13397 Marseille, France Univ. Bordeaux, IMS, UMR 5218, F-33400 Talence, France CNRS, IMS, UMR 5218, F-33400 Talence, France

Towards allosteric receptors – synthesis of β-cyclodextrin-functionalised 2,2’-bipyridines and their metal complexes

• Christopher Kremer,
• Gregor Schnakenburg and
• Arne Lützen

Beilstein J. Org. Chem. 2014, 10, 814–824, doi:10.3762/bjoc.10.77

• gratefully acknowledged. G.S. thanks Prof. Dr. A. C. Filippou for support. C.K. thanks the Studienstiftung des Deutschen Volkes for a doctoral scholarship.

A new manganese-mediated, cobalt-catalyzed three-component synthesis of (diarylmethyl)sulfonamides

• Antoine Pignon,
• Erwan Le Gall and
• Thierry Martens

Beilstein J. Org. Chem. 2014, 10, 425–431, doi:10.3762/bjoc.10.39

• Antoine Pignon Erwan Le Gall Thierry Martens Électrochimie et Synthèse Organique, Institut de Chimie et des Matériaux Paris-Est, UMR 7182 CNRS, Université Paris-Est Créteil, 2-8 rue Henri Dunant, 94320 Thiais, France 10.3762/bjoc.10.39 Abstract The synthesis of (diarylmethyl)sulfonamides and

Boron-substituted 1,3-dienes and heterodienes as key elements in multicomponent processes

• Ludovic Eberlin,
• Fabien Tripoteau,
• François Carreaux,
• Andrew Whiting and
• Bertrand Carboni

Beilstein J. Org. Chem. 2014, 10, 237–250, doi:10.3762/bjoc.10.19

• Ludovic Eberlin Fabien Tripoteau Francois Carreaux Andrew Whiting Bertrand Carboni Institut des Sciences Chimiques de Rennes, UMR 6226 CNRS-Université de Rennes 1, 263, Avenue du Général Leclerc, Campus de Beaulieu, Bâtiment 10A, 35042 Rennes Cedex, France Oméga Cat System, 11, allée de Beaulieu

Advancements in the mechanistic understanding of the copper-catalyzed azide–alkyne cycloaddition

• Regina Berg and
• Bernd F. Straub

Beilstein J. Org. Chem. 2013, 9, 2715–2750, doi:10.3762/bjoc.9.308

Synthesis of enones, pyrazolines and pyrrolines with gem-difluoroalkyl side chains

• Assaad Nasr El Dine,
• Ali Khalaf,
• Danielle Grée,
• Olivier Tasseau,
• Fares Fares,
• Nada Jaber,
• Philippe Lesot,
• Ali Hachem and
• René Grée

Beilstein J. Org. Chem. 2013, 9, 1943–1948, doi:10.3762/bjoc.9.230

• Assaad Nasr El Dine Ali Khalaf Danielle Gree Olivier Tasseau Fares Fares Nada Jaber Philippe Lesot Ali Hachem Rene Gree Université de Rennes 1, Institut des Sciences Chimiques de Rennes, CNRS UMR 6226, Avenue du Général Leclerc, 35042 Rennes Cedex, France Laboratory for Medicinal Chemistry and

Synthesis and biological activities of the respiratory chain inhibitor aurachin D and new ring versus chain analogues

• Xu-Wen Li,
• Jennifer Herrmann,
• Yi Zang,
• Philippe Grellier,
• Soizic Prado,
• Rolf Müller and
• Bastien Nay

Beilstein J. Org. Chem. 2013, 9, 1551–1558, doi:10.3762/bjoc.9.176

• Xu-Wen Li Jennifer Herrmann Yi Zang Philippe Grellier Soizic Prado Rolf Muller Bastien Nay Muséum National d’Histoire Naturelle, Unité Molécules de Communication et Adaptation des Micro-organismes (UMR 7245 CNRS-MNHN), 57 rue Cuvier (CP 54), 75005 Paris, France Department of Microbial Natural

An organocatalytic route to 2-heteroarylmethylene decorated N-arylpyrroles

• Alexandre Jean,
• Jérôme Blanchet,
• Jacques Rouden,
• Jacques Maddaluno and
• Michaël De Paolis

Beilstein J. Org. Chem. 2013, 9, 1480–1486, doi:10.3762/bjoc.9.168

• Alexandre Jean Jerome Blanchet Jacques Rouden Jacques Maddaluno Michael De Paolis Laboratoire de Chimie Moléculaire et Thio-organique, ENSICAEN, Université de Caen, CNRS Laboratoire des Fonctions Azotées et Oxygénées Complexes de l’IRCOF, CNRS UMR 6014 & FR 3038, Université et INSA de Rouen, Mont

Electron self-exchange activation parameters of diethyl sulfide and tetrahydrothiophene

• Martin Goez and
• Martin Vogtherr

Beilstein J. Org. Chem. 2013, 9, 1448–1454, doi:10.3762/bjoc.9.164

• , diethyl sulfide DES and tetrahydrothiophene THTP, for which we have barred the direct deprotonation at Cα by the choice of a suitable sensitizer; for these substrates, a relayed deprotonation is also impossible because they are not sufficiently basic; however, D•+ can stabilize by dimer formation with

• . As we will show, the activation parameters provide evidence that the observed exchange indeed takes place between dimeric radical cations and D. Results and Discussion On the AM1 level, the heats of formation of D and are −92 kJ/mol and −14 kJ/mol for diethyl sulfide DES as opposed to −69 kJ/mol and

• +85 kJ/mol for triethylamine, the quencher used in our earlier work [21][22][23], so for any sensitizer the radical pair containing lies about 75 kJ/mol higher above the reactants in the case of the amine. From the oxidation potentials in the literature (DES, 1.65 V [27]; triethylamine, 0.96 V [21

Synthesis of the calcilytic ligand NPS 2143

• Henrik Johansson,
• Thomas Cailly,
• Alex Rojas Bie Thomsen,
• Hans Bräuner-Osborne and
• Daniel Sejer Pedersen

Beilstein J. Org. Chem. 2013, 9, 1383–1387, doi:10.3762/bjoc.9.154

• ICORE) UFR des Sciences Pharmaceutiques, Bd Becquerel, F-14032 Caen, France 10.3762/bjoc.9.154 Abstract (R)-3 (NPS 2143) is a negative allosteric modulator of the human calcium-sensing receptor (CaSR) and as such represents an important pharmacological tool compound for studying the CaSR. Herein, we

Lanostane- and cycloartane-type triterpenoids from Abies balsamea oleoresin

• Serge Lavoie,
• Charles Gauthier,
• Jean Legault,
• Sylvain Mercier,
• Vakhtang Mshvildadze and
• André Pichette

Beilstein J. Org. Chem. 2013, 9, 1333–1339, doi:10.3762/bjoc.9.150

• Serge Lavoie Charles Gauthier Jean Legault Sylvain Mercier Vakhtang Mshvildadze Andre Pichette Université du Québec à Chicoutimi, Chaire de Recherche sur les Agents Anticancéreux d'Origine Végétale, Laboratoire d'Analyse et de Séparation des Essences Végétales (LASEVE), Département des Sciences

C–C Bond formation catalyzed by natural gelatin and collagen proteins

• Dennis Kühbeck,
• Basab Bijayi Dhar,
• Eva-Maria Schön,
• Carlos Cativiela,
• Vicente Gotor-Fernández and
• David Díaz Díaz

Beilstein J. Org. Chem. 2013, 9, 1111–1118, doi:10.3762/bjoc.9.123

• : Optimization studies, additional experiments, figures and tables. Acknowledgements This work was supported by the Universität Regensburg (Förderlinie C des Finanziellen Anreizsystems für Drittmitteleinwerbung), Ministerio de Ciencia e Innovación – FEDER (CTQ2010-17436), Gobierno de Aragón-FSE (research group

Synthesis of guanidinium–sulfonimide ion pairs: towards novel ionic liquid crystals

• Martin Butschies,
• Manuel M. Neidhardt,
• Markus Mansueto,
• Sabine Laschat and
• Stefan Tussetschläger

Beilstein J. Org. Chem. 2013, 9, 1093–1101, doi:10.3762/bjoc.9.121

• Information File 162: DSC traces of compounds 2a,b, 3a and X-ray data of compound 3b. Acknowledgements Generous financial support by the Studienstiftung des Deutschen Volkes (Fellowship for M.B.), the Deutsche Forschungsgemeinschaft, the Ministerium für Wissenschaft, Forschung und Kunst des Landes Baden

New core-pyrene π structure organophotocatalysts usable as highly efficient photoinitiators

• Sofia Telitel,
• Frédéric Dumur,
• Thomas Faury,
• Bernadette Graff,
• Mohamad-Ali Tehfe,
• Didier Gigmes,
• Jean-Pierre Fouassier and
• Jacques Lalevée

Beilstein J. Org. Chem. 2013, 9, 877–890, doi:10.3762/bjoc.9.101

• Sofia Telitel Frederic Dumur Thomas Faury Bernadette Graff Mohamad-Ali Tehfe Didier Gigmes Jean-Pierre Fouassier Jacques Lalevee Institut de Science des Matériaux de Mulhouse IS2M – UMR 7361 – UHA; 15, rue Jean Starcky, F-68057 Mulhouse Cedex, France Aix-Marseille Université, CNRS, Institut de