C–C Bond formation catalyzed by natural gelatin and collagen proteins

• Dennis Kühbeck,
• Basab Bijayi Dhar,
• Eva-Maria Schön,
• Carlos Cativiela,
• Vicente Gotor-Fernández and
• David Díaz Díaz

Beilstein J. Org. Chem. 2013, 9, 1111–1118, doi:10.3762/bjoc.9.123

• : Optimization studies, additional experiments, figures and tables. Acknowledgements This work was supported by the Universität Regensburg (Förderlinie C des Finanziellen Anreizsystems für Drittmitteleinwerbung), Ministerio de Ciencia e Innovación – FEDER (CTQ2010-17436), Gobierno de Aragón-FSE (research group

Synthesis of guanidinium–sulfonimide ion pairs: towards novel ionic liquid crystals

• Martin Butschies,
• Manuel M. Neidhardt,
• Markus Mansueto,
• Sabine Laschat and
• Stefan Tussetschläger

Beilstein J. Org. Chem. 2013, 9, 1093–1101, doi:10.3762/bjoc.9.121

• Information File 162: DSC traces of compounds 2a,b, 3a and X-ray data of compound 3b. Acknowledgements Generous financial support by the Studienstiftung des Deutschen Volkes (Fellowship for M.B.), the Deutsche Forschungsgemeinschaft, the Ministerium für Wissenschaft, Forschung und Kunst des Landes Baden

New core-pyrene π structure organophotocatalysts usable as highly efficient photoinitiators

• Sofia Telitel,
• Frédéric Dumur,
• Thomas Faury,
• Bernadette Graff,
• Mohamad-Ali Tehfe,
• Didier Gigmes,
• Jean-Pierre Fouassier and
• Jacques Lalevée

Beilstein J. Org. Chem. 2013, 9, 877–890, doi:10.3762/bjoc.9.101

• Sofia Telitel Frederic Dumur Thomas Faury Bernadette Graff Mohamad-Ali Tehfe Didier Gigmes Jean-Pierre Fouassier Jacques Lalevee Institut de Science des Matériaux de Mulhouse IS2M – UMR 7361 – UHA; 15, rue Jean Starcky, F-68057 Mulhouse Cedex, France Aix-Marseille Université, CNRS, Institut de

NHC-catalysed highly selective aerobic oxidation of nonactivated aldehydes

• Lennart Möhlmann,
• Stefan Ludwig and
• Siegfried Blechert

Beilstein J. Org. Chem. 2013, 9, 602–607, doi:10.3762/bjoc.9.65

• Lennart Mohlmann Stefan Ludwig Siegfried Blechert TU-Berlin – Berlin Institute of Technology, Institute of Chemistry, Straße des 17. Juni 115, 10623 Berlin, Germany. Fax: (+49)-30-314-29745; Tel:(+49)-30-314-22255 10.3762/bjoc.9.65 Abstract This publication describes a highly selective oxidation

One-pot tandem cyclization of enantiopure asymmetric cis-2,5-disubstituted pyrrolidines: Facile access to chiral 10-heteroazatriquinanes

• Ping-An Wang,
• Sheng-Yong Zhang and
• Henri B. Kagan

Beilstein J. Org. Chem. 2013, 9, 265–269, doi:10.3762/bjoc.9.32

• Ping-An Wang Sheng-Yong Zhang Henri B. Kagan Department of Medicinal Chemistry, School of Pharmacy, The Fourth Military Medical University, Changle Xilu 17, Xi-An, 710032, P. R. China Institut de Chimie Moléculaire et des Matériaux d’Orsay (ICMMO-UMR 8182, CNRS), Laboratoire de Catalyse

Intramolecular carbolithiation of N-allyl-ynamides: an efficient entry to 1,4-dihydropyridines and pyridines – application to a formal synthesis of sarizotan

• Wafa Gati,
• Mohamed M. Rammah,
• Mohamed B. Rammah and
• Gwilherm Evano

Beilstein J. Org. Chem. 2012, 8, 2214–2222, doi:10.3762/bjoc.8.250

• Wafa Gati Mohamed M. Rammah Mohamed B. Rammah Gwilherm Evano Institut Lavoisier de Versailles, UMR CNRS 8180, Université de Versailles Saint-Quentin-en-Yvelines, 45, avenue des Etats-Unis, 78035 Versailles Cedex, France Laboratoire de Chimie Organique Hétérocyclique LCOH/LCOHSNR-LR11ES39

• , Département de Chimie, Faculté des Sciences de Monastir, Université de Monastir, avenue de l’environnement, 5019 Monastir, Tunisia, Laboratoire de Chimie Organique, Service de Chimie et PhysicoChimie Organiques, Université Libre de Bruxelles, Avenue F. D. Roosevelt 50, CP160/06, 1050 Brussels, Belgium

The chemistry of bisallenes

• Henning Hopf and
• Georgios Markopoulos

Beilstein J. Org. Chem. 2012, 8, 1936–1998, doi:10.3762/bjoc.8.225

Impact of cyclodextrins on the behavior of amphiphilic ligands in aqueous organometallic catalysis

• Hervé Bricout,
• Estelle Léonard,
• Christophe Len,
• David Landy,
• Frédéric Hapiot and
• Eric Monflier

Beilstein J. Org. Chem. 2012, 8, 1479–1484, doi:10.3762/bjoc.8.167

• Herve Bricout Estelle Leonard Christophe Len David Landy Frederic Hapiot Eric Monflier Université Lille Nord de France, CNRS UMR 8181, Unité de Catalyse et de Chimie du Solide - UCCS, UArtois, Faculté des Sciences Jean Perrin, SP18, 62307 Lens Cedex, France Université de Technologie de Compiègne

Building photoswitchable 3,4'-AMPB peptides: Probing chemical ligation methods with reducible azobenzene thioesters

• Gehad Zeyat and
• Karola Rück-Braun

Beilstein J. Org. Chem. 2012, 8, 890–896, doi:10.3762/bjoc.8.101

• Gehad Zeyat Karola Ruck-Braun Institut für Chemie, Technische Universität Berlin, Strasse des 17. Juni 135, 10623 Berlin, Germany 10.3762/bjoc.8.101 Abstract Photoswitchable peptides were synthesized by using cysteine- and auxiliary-based native chemical ligation reactions. For this purpose, the

Syntheses and applications of furanyl-functionalised 2,2’:6’,2’’-terpyridines

• Jérôme Husson and
• Michael Knorr

Beilstein J. Org. Chem. 2012, 8, 379–389, doi:10.3762/bjoc.8.41

• Jerome Husson Michael Knorr Institut UTINAM UMR CNRS 6213, Université de Franche-Comté, Faculté des Sciences et des Techniques, 16 Route de Gray, 25030 Besançon, France; Tel.: +33-3-81676291, Fax: +33-3-81676738 10.3762/bjoc.8.41 Abstract Different synthetic routes leading to terpyridines

Synthesis and mesomorphic properties of calamitic malonates and cyanoacetates tethered to 4-cyanobiphenyls

• Katharina C. Kress,
• Martin Kaller,
• Kirill V. Axenov,
• Stefan Tussetschläger and
• Sabine Laschat

Beilstein J. Org. Chem. 2012, 8, 371–378, doi:10.3762/bjoc.8.40

• Forschung, the Ministerium für Wissenschaft, Forschung und Kunst des Landes Baden-Württemberg and the Max-Planck-Gesellschaft (International Max Planck Research School for Advanced Materials fellowship for M.K.) is gratefully acknowledged. We would like to thank Ingo Dierking for helpful discussions and

Liquid-crystalline nanoparticles: Hybrid design and mesophase structures

• Gareth L. Nealon,
• Romain Greget,
• Cristina Dominguez,
• Zsuzsanna T. Nagy,
• Daniel Guillon,
• Jean-Louis Gallani and
• Bertrand Donnio

Beilstein J. Org. Chem. 2012, 8, 349–370, doi:10.3762/bjoc.8.39

• Gareth L. Nealon Romain Greget Cristina Dominguez Zsuzsanna T. Nagy Daniel Guillon Jean-Louis Gallani Bertrand Donnio Institut de Physique et Chimie des Matériaux de Strasbourg (IPCMS), CNRS-Université de Strasbourg (UMR 7504), 23 rue du Loess, BP 43, 67034 Strasbourg Cedex 2, France 10.3762/bjoc

Double N-arylation reaction of polyhalogenated 4,4’-bipyridines. Expedious synthesis of functionalized 2,7-diazacarbazoles

• Mohamed Abboud,
• Emmanuel Aubert and
• Victor Mamane

Beilstein J. Org. Chem. 2012, 8, 253–258, doi:10.3762/bjoc.8.26

• Mohamed Abboud Emmanuel Aubert Victor Mamane Structure et Réactivité des Systèmes Moléculaires Complexes (SRSMC), UMR CNRS-UHP 7565 Nancy Université, BP 70239, Bd des Aiguillettes, 54506 Vandoeuvre-les-Nancy, France Cristallographie, Résonance Magnétique et Modélisations (CRM2), UMR CNRS-UHP 7036

• Nancy Université, BP 70239, Bd des Aiguillettes, 54506 Vandoeuvre-les-Nancy, France 10.3762/bjoc.8.26 Abstract Unusual 2,7-diazacarbazoles were prepared in one step from readily available tetra-halogenated 4,4’-bipyridines by using a double N-arylation reaction in the presence of the Pd–XPhos catalyst

Synthesis of multivalent host and guest molecules for the construction of multithreaded diamide pseudorotaxanes

• Nora L. Löw,
• Egor V. Dzyuba,
• Boris Brusilowskij,
• Lena Kaufmann,
• Elisa Franzmann,
• Wolfgang Maison,
• Emily Brandt,
• Daniel Aicher,
• Arno Wiehe and
• Christoph A. Schalley

Beilstein J. Org. Chem. 2012, 8, 234–245, doi:10.3762/bjoc.8.24

• "multivalency") and the Fonds der Chemischen Industrie (FCI). E.V.D. and L. K. thank the Studienstiftung des deutschen Volkes for a PhD scholarship. We thank Gülsah Ayvalik, B.Sc. for her help with the synthesis of starting materials and Dr. Andreas Schäfer for helpful comments on the interpretation of the NMR

Selectivity in C-alkylation of dianions of protected 6-methyluridine

• Ngoc Hoa Nguyen,
• Christophe Len,
• Anne-Sophie Castanet and
• Jacques Mortier

Beilstein J. Org. Chem. 2011, 7, 1228–1233, doi:10.3762/bjoc.7.143

• Ngoc Hoa Nguyen Christophe Len Anne-Sophie Castanet Jacques Mortier Université du Maine and CNRS, Unité de chimie organique moléculaire et macromoléculaire (UMR 6011), Faculté des sciences, avenue Olivier Messiaen, 72085 Le Mans Cedex 9, France Université de technologie de Compiègne

Amine-linked diglycosides: Synthesis facilitated by the enhanced reactivity of allylic electrophiles, and glycosidase inhibition assays

• Ian Cumpstey,
• Jens Frigell,
• Elias Pershagen,
• Tashfeen Akhtar,
• Elena Moreno-Clavijo,
• Inmaculada Robina,
• Dominic S. Alonzi and
• Terry D. Butters

Beilstein J. Org. Chem. 2011, 7, 1115–1123, doi:10.3762/bjoc.7.128

• Ian Cumpstey Jens Frigell Elias Pershagen Tashfeen Akhtar Elena Moreno-Clavijo Inmaculada Robina Dominic S. Alonzi Terry D. Butters Department of Organic Chemistry, The Arrhenius Laboratory, Stockholm University, 106 91 Stockholm, Sweden Institut de Chimie des Substances Naturelles, Centre

A practical route to tertiary diarylmethylamides or -carbamates from imines, organozinc reagents and acyl chlorides or chloroformates

• Erwan Le Gall,
• Antoine Pignon and
• Thierry Martens

Beilstein J. Org. Chem. 2011, 7, 997–1002, doi:10.3762/bjoc.7.112

• Erwan Le Gall Antoine Pignon Thierry Martens Électrochimie et Synthèse Organique, Institut de Chimie et des Matériaux Paris-Est, UMR 7182 CNRS - Université Paris-Est Créteil, 2-8 rue Henri Dunant, 94320 Thiais, France 10.3762/bjoc.7.112 Abstract A practical route to tertiary diarylmethylamides or

A practical two-step procedure for the preparation of enantiopure pyridines: Multicomponent reactions of alkoxyallenes, nitriles and carboxylic acids followed by a cyclocondensation reaction

• Christian Eidamshaus,
• Roopender Kumar,
• Mrinal K. Bera and
• Hans-Ulrich Reissig

Beilstein J. Org. Chem. 2011, 7, 962–975, doi:10.3762/bjoc.7.108

• this work by the Deutsche Forschungsgemeinschaft (SFB 765), the Studienstiftung des Deutschen Volkes (PhD fellowship to CE) and the Bayer Schering Pharma AG is most gratefully acknowledged. We thank Dr. R. Zimmer for help during the preparation of the manuscript.

Gold-catalyzed propargylic substitutions: Scope and synthetic developments

• Olivier Debleds,
• Eric Gayon,
• Emmanuel Vrancken and
• Jean-Marc Campagne

Beilstein J. Org. Chem. 2011, 7, 866–877, doi:10.3762/bjoc.7.99

• -hydroxylamine cyclization. Acknowledgements We are grateful to the CNRS for financial support (ATIPE jeune équipe), the Institut de Chimie des Substances Naturelles (Gif sur Yvette), the MESR (E. G. Ph.D. grant) and the Ecole Nationale Supérieure de Chimie de Montpellier.

Metathesis access to monocyclic iminocyclitol-based therapeutic agents

• Ileana Dragutan,
• Valerian Dragutan,
• Carmen Mitan,
• Hermanus C.M. Vosloo,
• Lionel Delaude and
• Albert Demonceau

Beilstein J. Org. Chem. 2011, 7, 699–716, doi:10.3762/bjoc.7.81

• [70] to prepare 5-des(hydroxymethyl)-1-deoxynojirimycin (114) and its mannose analogue 111 (as HCl salts) in a highly stereoselective mode starting from a different common olefin, 107 (Scheme 20). In this case, RCM was promoted by the 2nd-generation Grubbs catalyst 5 which ensured a high yield of the

• ). Synthesis of 1-deoxymannonojirimycin (63) and 1-deoxyaltronojirimycin (65). Synthesis of 5-des(hydroxymethyl)-1-deoxymannonojirimycin (111) and 5-des(hydroxymethyl)-1-deoxynojirimycin (114). Synthesis of D-1-deoxygulonojirimycin (91) and L-1-deoxyallonojirimycin (122). Total synthesis of fagomine (129), 3

Olefin metathesis in nano-sized systems

• Didier Astruc,
• Abdou K. Diallo,
• Sylvain Gatard,
• Liyuan Liang,
• Cátia Ornelas,
• Victor Martinez,
• Denise Méry and
• Jaime Ruiz

Beilstein J. Org. Chem. 2011, 7, 94–103, doi:10.3762/bjoc.7.13

• Didier Astruc Abdou K. Diallo Sylvain Gatard Liyuan Liang Catia Ornelas Victor Martinez Denise Mery Jaime Ruiz Institut des Sciences Moléculaires, UMR CNRS No 5255, Université Bordeaux 1, 351 Cours de la Libération, 33405 Talence Cedex, France 10.3762/bjoc.7.13 Abstract The interplay between

Identification and synthesis of impurities formed during sertindole preparation

• I. V. Sunil Kumar,
• G. S. R. Anjaneyulu and
• V. Hima Bindu

Beilstein J. Org. Chem. 2011, 7, 29–33, doi:10.3762/bjoc.7.5

• Discussion During the catalytic hydrogenation of indole 15, formation of 0.5–1.0% of the des-chloro indole 17 is observed; the level is reduced to less than 0.1% during its isolation and purification. It is necessary to remove the impurity at this stage because after condensation with imidazolidinone 16, it

• is difficult to remove the des-chloro sertindole 2, from sertindole, without significant loss in yield. The impurity 2 was prepared by palladium catalyzed hydrogenation of indole 9 and the des-chloro indole 17 formed was condensed with imidazolidinone 16, under Finkelstein conditions (Scheme 2). The

• tetrahydropyridinyl moiety in indole 19, this reaction was utilized to synthesize the des-fluoro sertindole 3. Thus prolonged hydrogenation of 19 afforded des-fluoro indole 22, which on condensation with imidazolidinone 16 afforded the desired compound 3 (Scheme 5). The contamination by 3 in sertindole (1) was 0.20

Carbasugar analogues of galactofuranosides: α-O-linked derivatives

• Jens Frigell and
• Ian Cumpstey

Beilstein J. Org. Chem. 2010, 6, 1127–1131, doi:10.3762/bjoc.6.129

• Jens Frigell Ian Cumpstey Department of Organic Chemistry, The Arrhenius Laboratory, Stockholm University, Stockholm 106 91, Sweden Institut de Chimie des Substances Naturelles, CNRS, 91198 Gif-sur-Yvette, France, Tel.: +33 (0)1 69 82 30 78; fax: +33 (0)1 69 07 72 47 10.3762/bjoc.6.129 Abstract

Backbone tuning in indenylidene–ruthenium complexes bearing an unsaturated N-heterocyclic carbene

• César A. Urbina-Blanco,
• Xavier Bantreil,
• Hervé Clavier,
• Alexandra M. Z. Slawin and
• Steven P. Nolan

Beilstein J. Org. Chem. 2010, 6, 1120–1126, doi:10.3762/bjoc.6.128

• Cesar A. Urbina-Blanco Xavier Bantreil Herve Clavier Alexandra M. Z. Slawin Steven P. Nolan EaStCHEM School of Chemistry, University of St Andrews, St Andrews KY16 9ST, United Kingdom present address: Institut des Sciences Moléculaires de Marseille Université Aix-Marseille, UMR CNRS 6263, France

Organic gelators and hydrogelators

• Jean-Pierre Desvergne

Beilstein J. Org. Chem. 2010, 6, 846–847, doi:10.3762/bjoc.6.99

• Jean-Pierre Desvergne Institut des Science Moléculaires, Université Bordeaux 1 - CNRS UMR 5255, 351 cours de la Libération, 33405 Talence Cedex, France 10.3762/bjoc.6.99 The design and control of molecular self-assembly is of great interest in the development of new molecular architectures with