Hoveyda–Grubbs type metathesis catalyst immobilized on mesoporous molecular sieves MCM-41 and SBA-15

• Hynek Balcar,
• Tushar Shinde,
• Naděžda Žilková and
• Zdeněk Bastl

Beilstein J. Org. Chem. 2011, 7, 22–28, doi:10.3762/bjoc.7.4

• used. This usually requires a sophisticated synthetic procedure. Moreover, the changes in the Ru coordination sphere may lead to the decrease in catalyst activity (e.g., the exchange of chloro ligands for carboxylates [10][11]). Recently, a convenient method for the immobilization of Hoveyda–Grubbs

Anthracene appended pyridinium amide–urea conjugate in selective fluorometric sensing of L-N-acetylvaline salt

• Kumaresh Ghosh,
• Tanmay Sarkar and
• Asoke P. Chattopadhyay

Beilstein J. Org. Chem. 2010, 6, 1211–1218, doi:10.3762/bjoc.6.139

• ; pyridinium amide–urea conjugate; Introduction The design and synthesis of artificial receptors capable of recognizing α-hydroxy and N-acetyl-α-amino acid carboxylates (i.e., salts of α-amino acids) is an active area of interest in supramolecular chemistry due to the biological significance and practical

• carboxylates [21][22], we reported receptors of various structures with different binding sites. The pyridinium motif, which was first used by Jeong et al. for carboxylate binding [23], was one of the binding sites in our designed receptors [24][25][26]. The pyridinium motif is unique due to its contribution

Aromatic and heterocyclic perfluoroalkyl sulfides. Methods of preparation

• Vladimir N. Boiko

Beilstein J. Org. Chem. 2010, 6, 880–921, doi:10.3762/bjoc.6.88

Preparation of aminoethyl glycosides for glycoconjugation

• Robert Šardzík,
• Gavin T. Noble,
• Martin J. Weissenborn,
• Andrew Martin,
• Simon J. Webb and
• Sabine L. Flitsch

Beilstein J. Org. Chem. 2010, 6, 699–703, doi:10.3762/bjoc.6.81

• that aminoethyl glycosides are conveniently conjugated to surfaces containing activated carboxylates, they have become a useful generic anomeric functional group for glycoconjugation. The importance of this linker merits efforts into finding a robust synthetic method than can be used by scientists who

Suzuki–Miyaura cross-coupling reaction of 1-aryltriazenes with arylboronic acids catalyzed by a recyclable polymer-supported N-heterocyclic carbene–palladium complex catalyst

• Guangming Nan,
• Fang Ren and
• Meiming Luo

Beilstein J. Org. Chem. 2010, 6, No. 70, doi:10.3762/bjoc.6.70

• reaction has evolved as a powerful synthetic tool for the synthesis of unsymmetrical biaryls in both academic laboratories and industry [5][6][7][8]. Most of the reported Suzuki–Miyaura reactions are based on the use of aryl halides and triflates, and recently sulfonates and carboxylates, as the

Shelf-stable electrophilic trifluoromethylating reagents: A brief historical perspective

• Norio Shibata,
• Andrej Matsnev and
• Dominique Cahard

Beilstein J. Org. Chem. 2010, 6, No. 65, doi:10.3762/bjoc.6.65

• , tetralone and oxocyclopentane carboxylates gave the corresponding trifluoromethylated products in 52–92% yields (Scheme 36). In the case of an acyclic ester, a good yield was achieved only in the presence of the phosphazene base P2-Et. When the reaction was carried out in the presence of nitrobenzene there

Anion receptors containing thiazine-1,1-dioxide heterocycles as hydrogen bond donors

• Hong-Bo Wang,
• James A. Wisner and
• Michael C. Jennings

Beilstein J. Org. Chem. 2010, 6, No. 50, doi:10.3762/bjoc.6.50

• potential hydrogen bond donor strength with anionic guests. Alternatively, the possibility of deprotonation in some specific systems by basic anions such as carboxylates or fluoride can be employed as an indicator for these species. Regardless, the incorporation of sulfonamide functional groups has

Pd-catalyzed decarboxylative Heck vinylation of 2-nitrobenzoates in the presence of CuF₂

• Lukas J. Gooßen,
• Bettina Zimmermann and
• Thomas Knauber

Beilstein J. Org. Chem. 2010, 6, No. 43, doi:10.3762/bjoc.6.43

• substrate range with regard to the carboxylate substrate and found that the new protocol is particularly suitable for 2-nitro-substituted carboxylates (Table 3). Various compounds of this type were converted to stilbenes in good yields. In contrast, arenecarboxylates with a nitro-group in meta- or para

• Combi Flash Companion-Chromatography-System (Isco-Systems) and RediSep packed columns (12 g). General procedure for the synthesis of the potassium carboxylates A 250 mL, two-necked, round-bottomed flask was charged with the carboxylic acid (20 mmol) and ethanol (20 mL). To this, a solution of potassium

• Büchner funnel, washed sequentially with ethanol (2 × 10 mL) and cold (0 °C) diethyl ether (10 mL), transferred to a round-bottomed flask, and dried at 2 × 10−3 mmHg to provide the corresponding potassium carboxylates 1a–i in 70–98% yield. General procedure for the decarboxylative Heck vinylation An oven

Molecular recognition of organic ammonium ions in solution using synthetic receptors

• Andreas Späth and
• Burkhard König

Beilstein J. Org. Chem. 2010, 6, No. 32, doi:10.3762/bjoc.6.32

Iridium-catalyzed asymmetric ring-opening reactions of oxabicyclic alkenes with secondary amine nucleophiles

• Dingqiao Yang,
• Ping Hu,
• Yuhua Long,
• Yujuan Wu,
• Heping Zeng,
• Hui Wang and
• Xiongjun Zuo

Beilstein J. Org. Chem. 2009, 5, No. 53, doi:10.3762/bjoc.5.53

• -catalyzed asymmetric ring-opening of oxabenzonorbornadiene with a wide range of nucleophiles including thiols [10], phenols [11], organoboronic acids [12][13], dialkylzincs [14][15], carboxylates [16], sulfur nucleophiles [17], and various amines [18][19]. In addition to rhodium catalysts, other transition

An easy synthesis of 5-functionally substituted ethyl 4-amino- 1-aryl- pyrazolo- 3-carboxylates: interesting precursors to sildenafil analogues

• Said A. S. Ghozlan,
• Khadija O. Badahdah and
• Ismail A. Abdelhamid

Beilstein J. Org. Chem. 2007, 3, No. 15, doi:10.1186/1860-5397-3-15

• arylhydrazononitriles 1a-c are valuable precursors to 4-amino-5-substituted-1-aryl-1H-pyrazole-3-carboxylic acid ethyl ester which can be used for preparation of sildenafil analogues. synthesis of Ethyl 4-amino-5-substituted-1-aryl-1H-pyrazole-3-carboxylates (4) Reactivity of pyrazole 4b with phenylisothiocyanate and

Crystal engineering of analogous and homologous organic compounds: hydrogen bonding patterns in trimethoprim hydrogen phthalate and trimethoprim hydrogen adipate

• Packianathan Thomas Muthiah,
• Savarimuthu Francis,
• Urszula Rychlewska and
• Beata Warżajtis

Beilstein J. Org. Chem. 2006, 2, No. 8, doi:10.1186/1860-5397-2-8

• motifs in organic crystal structures [25]. This has also been observed in the crystal structures of trimethoprim carboxylates such as trimethoprim salicylate monohydrate [26], trimethoprim acetate [9], trimethoprim salicylate methanol solvate [19], trimethoprim benzoate [10] etc,. This fork-like hydrogen