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Search for "characterization" in Full Text gives 1534 result(s) in Beilstein Journal of Organic Chemistry. Showing first 200.

Synthesis of π-conjugated polycyclic compounds by late-stage extrusion of chalcogen fragments

  • Aissam Okba,
  • Pablo Simón Marqués,
  • Kyohei Matsuo,
  • Naoki Aratani,
  • Hiroko Yamada,
  • Gwénaël Rapenne and
  • Claire Kammerer

Beilstein J. Org. Chem. 2024, 20, 287–305, doi:10.3762/bjoc.20.30

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  • endoperoxide formation. To overcome these issues, the “precursor approach” was developed and relies on the synthesis, purification and characterization of soluble and stable precursors of the target active π-CPCs, followed by their (solution) processing and their final deprotection once assembled in thin-films
  • in-solution organic chemistry techniques, ii) for their improved processing, as well as iii) for their in situ structural characterization and electronic investigation both at the material and single-molecule scales. Reactions involving the elimination of carbon-based small molecules, i.e., retro
  • ” is particularly interesting, since the as-prepared π-extended structures can undergo in-depth structural characterization and electronic investigations in situ at the single molecule scale, thanks to scanning probe microscopy and spectroscopy. The synthetic route relying on O-extrusion was thus
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Published 15 Feb 2024

Unveiling the regioselectivity of rhodium(I)-catalyzed [2 + 2 + 2] cycloaddition reactions for open-cage C70 production

  • Cristina Castanyer,
  • Anna Pla-Quintana,
  • Anna Roglans,
  • Albert Artigas and
  • Miquel Solà

Beilstein J. Org. Chem. 2024, 20, 272–279, doi:10.3762/bjoc.20.28

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  • derivatives are relatively scarce, likely owing to the challenges associated with their synthesis and the characterization of asymmetric structures. The findings of this study contribute to the ongoing efforts in the field of fullerene chemistry and provide a foundation for further exploration of
  • (fulleroid) derivatives 2a and 2b. Supporting Information Supporting Information File 22: General materials and methods, experimental procedures and characterization of all new compounds. Acknowledgements Dr. Carles Fuertes-Espinosa is acknowledged for assistance in HPLC and UV–vis experiments. Funding We
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Published 13 Feb 2024

Nucleophilic functionalization of thianthrenium salts under basic conditions

  • Xinting Fan,
  • Duo Zhang,
  • Xiangchuan Xiu,
  • Bin Xu,
  • Yu Yuan,
  • Feng Chen and
  • Pan Gao

Beilstein J. Org. Chem. 2024, 20, 257–263, doi:10.3762/bjoc.20.26

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  • )thianthrenium salt.a Supporting Information Supporting Information File 16: Experimental procedures, characterization data for all new compounds, and NMR spectra of products. Funding We are grateful for the financial support from the National Natural Science Foundation of China (22001227), the China
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Published 08 Feb 2024

Photochromic derivatives of indigo: historical overview of development, challenges and applications

  • Gökhan Kaplan,
  • Zeynel Seferoğlu and
  • Daria V. Berdnikova

Beilstein J. Org. Chem. 2024, 20, 228–242, doi:10.3762/bjoc.20.23

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  • forward and backward isomerization of N,N'-diacetylindigo (9a) in toluene without isolation of the Z-form [49]. The Fischer method remains relevant up to date and is frequently used for the characterization of the photoinduced forms of various indigoid photoswitches [50][51][52][53][54]. To assess an
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Published 07 Feb 2024

Optimizations of lipid II synthesis: an essential glycolipid precursor in bacterial cell wall synthesis and a validated antibiotic target

  • Milandip Karak,
  • Cian R. Cloonan,
  • Brad R. Baker,
  • Rachel V. K. Cochrane and
  • Stephen A. Cochrane

Beilstein J. Org. Chem. 2024, 20, 220–227, doi:10.3762/bjoc.20.22

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  • Supporting Information Supporting Information File 12: Experimental procedures, characterization data, and selected copies of 1H, 13C, and 31P NMR spectra. Acknowledgements We extend our gratitude to Professor Alethea Tabor and Professor Stefan Howorka from University College London for their valuable
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Published 06 Feb 2024

Chiral phosphoric acid-catalyzed transfer hydrogenation of 3,3-difluoro-3H-indoles

  • Yumei Wang,
  • Guangzhu Wang,
  • Yanping Zhu and
  • Kaiwu Dong

Beilstein J. Org. Chem. 2024, 20, 205–211, doi:10.3762/bjoc.20.20

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  • . Reaction optimization studies.a The effect of Hantzsch esters and other reaction parameters.a Supporting Information Supporting Information File 4: Full experimental details and characterization data of all compounds. Funding We are grateful for the financial support provided by the National Nature
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Published 01 Feb 2024

Comparison of glycosyl donors: a supramer approach

  • Anna V. Orlova,
  • Nelly N. Malysheva,
  • Maria V. Panova,
  • Nikita M. Podvalnyy,
  • Michael G. Medvedev and
  • Leonid O. Kononov

Beilstein J. Org. Chem. 2024, 20, 181–192, doi:10.3762/bjoc.20.18

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  • characterization Methyl (phenyl 4,9-bis-O-chloroacetyl-3,5-dideoxy-2-thio-5-trifluoroacetamido-7,8-bis-O-trifluoroacetyl-ᴅ-glycero-β-ᴅ-galacto-nonulopyranosid)onate (2) To the solution of diol 7 (124.9 mg, 0.2 mmol, dried in vacuo at 0.1 Torr for 1 h) in (CF3CO)2O (4 mL), sodium trifluoroacetate (25 mg, freshly
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Published 31 Jan 2024

Copper-promoted C5-selective bromination of 8-aminoquinoline amides with alkyl bromides

  • Changdong Shao,
  • Chen Ma,
  • Li Li,
  • Jingyi Liu,
  • Yanan Shen,
  • Chen Chen,
  • Qionglin Yang,
  • Tianyi Xu,
  • Zhengsong Hu,
  • Yuhe Kan and
  • Tingting Zhang

Beilstein J. Org. Chem. 2024, 20, 155–161, doi:10.3762/bjoc.20.14

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  • conditions for the copper-promoted C5-brominationa. Supporting Information Supporting Information File 38: General information, experimental procedures for all the products, characterization data, and NMR spectra. Funding This work was supported by the National Natural Science Foundation of China (21801088
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Published 23 Jan 2024

Visible-light-induced radical cascade cyclization: a catalyst-free synthetic approach to trifluoromethylated heterocycles

  • Chuan Yang,
  • Wei Shi,
  • Jian Tian,
  • Lin Guo,
  • Yating Zhao and
  • Wujiong Xia

Beilstein J. Org. Chem. 2024, 20, 118–124, doi:10.3762/bjoc.20.12

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  • Supporting Information Supporting Information File 35: Characterization data and copies of spectra. Supporting Information File 36: Crystallographic information file (cif) of X-ray structure for compound 3m. Funding We are grateful for the financial support from the Science and Technology Plan of Shenzhen
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Published 19 Jan 2024

Optimizing reaction conditions for the light-driven hydrogen evolution in a loop photoreactor

  • Pengcheng Li,
  • Daniel Kowalczyk,
  • Johannes Liessem,
  • Mohamed M. Elnagar,
  • Dariusz Mitoraj,
  • Radim Beranek and
  • Dirk Ziegenbalg

Beilstein J. Org. Chem. 2024, 20, 74–91, doi:10.3762/bjoc.20.9

Graphical Abstract
  • hydrogen generation is designed and equipped with 365 nm LEDs. Fluid dynamics in the loop photoreactor are characterized using a color tracer mixing experiment and image analysis. Photonic characterization is performed with the ferrioxalate actinometer. Finally, the photocatalytic hydrogen evolution with
  • activity of the hydrogen evolution. The efficiency of the loop photoreactor is also compared with results from literature obtained in a Schlenk tube system [30]. Results and Discussion Photocatalyst characterization The surface morphology of the Pt-PCN photocatalyst has been analyzed by scanning electron
  • of Pt on the surfaces of PCN over all particles. Moreover, the EDX elemental composition analysis indicates that the Pt content is 0.6 atom %. Reactor characterization Fluid flow pattern Figure 3 shows four representative frames of a mixing experiment at times of 1.2, 2.2, 4.2, and 7.8 s using a
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Published 16 Jan 2024

Multi-redox indenofluorene chromophores incorporating dithiafulvene donor and ene/enediyne acceptor units

  • Christina Schøttler,
  • Kasper Lund-Rasmussen,
  • Line Broløs,
  • Philip Vinterberg,
  • Ema Bazikova,
  • Viktor B. R. Pedersen and
  • Mogens Brøndsted Nielsen

Beilstein J. Org. Chem. 2024, 20, 59–73, doi:10.3762/bjoc.20.8

Graphical Abstract
  • easily degrade, which made their characterization somewhat difficult (vide infra). We also targeted other enediyne acetylenic scaffolds with IF as central core as shown in Scheme 5. Starting from IF dione 1, compounds 24 and 25 were synthesized via Ramirez/Corey–Fuchs dibromo-olefinations. Four-fold
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Published 15 Jan 2024

Preparing a liquid crystalline dispersion of carbon nanotubes with high aspect ratio

  • Keiko Kojima,
  • Nodoka Kosugi,
  • Hirokuni Jintoku,
  • Kazufumi Kobashi and
  • Toshiya Okazaki

Beilstein J. Org. Chem. 2024, 20, 52–58, doi:10.3762/bjoc.20.7

Graphical Abstract
  • carbon nanotube dispersions with high aspect ratios, we utilized DWCNTs obtained from Shenzhen Nanotech Port Co. Ltd. Supporting Information File 1 provides characterization details. Briefly, the Raman G/D ratio was approximately 37 (Supporting Information File 1, Figure S1d), indicating high
  • substrate, is necessary to fully utilize CNT-LC dispersions. Experimental Characterization of DWCNT DWCNTs were purchased from Shenzhen Nanotech Port Co. Ltd. (NTP9112, Product Number DW220817). For the transmission electron microscope observations (Topcon Corporation, EM-002B), DWCNTs were suspended in
  • were sealed by UV resin. After the samples were left for one week, the liquid phases were observed using an OLYMPUS BX51 polarized optical microscope (POM). Preparation and characterization of DWCNT film The DWCNT film was prepared from the dispersion with nematic phase by bar-coating method. Initially
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Published 11 Jan 2024

Facile access to pyridinium-based bent aromatic amphiphiles: nonionic surface modification of nanocarbons in water

  • Lorenzo Catti,
  • Shinji Aoyama and
  • Michito Yoshizawa

Beilstein J. Org. Chem. 2024, 20, 32–40, doi:10.3762/bjoc.20.5

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  • -CNT)m and (PA-Im)n·(C60)m under neutral/acidic conditions [23]. Supporting Information Supporting Information File 28: General information, experimental procedures, characterization data, and copies of spectra. Acknowledgements Zeta potential measurements were performed with the help of Prof
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Published 08 Jan 2024

NMRium: Teaching nuclear magnetic resonance spectra interpretation in an online platform

  • Luc Patiny,
  • Hamed Musallam,
  • Alejandro Bolaños,
  • Michaël Zasso,
  • Julien Wist,
  • Metin Karayilan,
  • Eva Ziegler,
  • Johannes C. Liermann and
  • Nils E. Schlörer

Beilstein J. Org. Chem. 2024, 20, 25–31, doi:10.3762/bjoc.20.4

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  • (practical laboratory classes including examples of synthesis and compound characterization), NMRium provides a full 1D FT workflow and therefore an ideal possibility to introduce basic concepts of data processing, data presentation, and data evaluation. Spectra from most NMR instruments may be directly used
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Published 05 Jan 2024

Cycloaddition reactions of heterocyclic azides with 2-cyanoacetamidines as a new route to C,N-diheteroarylcarbamidines

  • Pavel S. Silaichev,
  • Tetyana V. Beryozkina,
  • Vsevolod V. Melekhin,
  • Valeriy O. Filimonov,
  • Andrey N. Maslivets,
  • Vladimir G. Ilkin,
  • Wim Dehaen and
  • Vasiliy A. Bakulev

Beilstein J. Org. Chem. 2024, 20, 17–24, doi:10.3762/bjoc.20.3

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  • embryo kidney cells (HEK-293), glioblastoma (A-172), and osteosarcoma (HOS) cells. Supporting Information Supporting Information File 25: Full experimental details and characterization data of all new compounds. Supporting Information File 26: Copies of NMR spectra of all new compounds. Funding Design
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Published 05 Jan 2024

Long oligodeoxynucleotides: chemical synthesis, isolation via catching-by-polymerization, verification via sequencing, and gene expression demonstration

  • Yipeng Yin,
  • Reed Arneson,
  • Alexander Apostle,
  • Adikari M. D. N. Eriyagama,
  • Komal Chillar,
  • Emma Burke,
  • Martina Jahfetson,
  • Yinan Yuan and
  • Shiyue Fang

Beilstein J. Org. Chem. 2023, 19, 1957–1965, doi:10.3762/bjoc.19.146

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  • ], direct evidence is lacking in the literature. For the CBP method to be practically useful, we believe that characterization of the ODNs via DNA sequencing is imperative. Based on this reasoning, ODNs from three colonies originated from the 399 nt GFP gene fragment were sequenced (see Supporting
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Published 21 Dec 2023

Construction of diazepine-containing spiroindolines via annulation reaction of α-halogenated N-acylhydrazones and isatin-derived MBH carbonates

  • Xing Liu,
  • Wenjing Shi,
  • Jing Sun and
  • Chao-Guo Yan

Beilstein J. Org. Chem. 2023, 19, 1923–1932, doi:10.3762/bjoc.19.143

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  • , for other compounds α-bromo-N-tosylhydrazone was used. Yields refer to isolated compounds. Proposed reaction mechanism. Gram-scale synthesis of compound 7c. Optimizing the reaction conditions.a Supporting Information Supporting Information File 22: Characterization data and 1H, 13C NMR, and HRMS
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Published 18 Dec 2023

Thienothiophene-based organic light-emitting diode: synthesis, photophysical properties and application

  • Recep Isci and
  • Turan Ozturk

Beilstein J. Org. Chem. 2023, 19, 1849–1857, doi:10.3762/bjoc.19.137

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  • sieves (4 Å). Dichloromethane (Aldrich), methanol (Merck), and sodium carbonate (Merck) were used as received. Compounds 2–6 were synthesized following our previous reports [20][21][22][23][44][45][46][47]. The characterization data of 7 and 8 are compatible with the published data in ref. [23
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Published 07 Dec 2023

Active-metal template clipping synthesis of novel [2]rotaxanes

  • Cătălin C. Anghel,
  • Teodor A. Cucuiet,
  • Niculina D. Hădade and
  • Ion Grosu

Beilstein J. Org. Chem. 2023, 19, 1776–1784, doi:10.3762/bjoc.19.130

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  • beautiful structures and intriguing properties. We present herein a new synthetic strategy to access [2]rotaxanes, namely active-metal template clipping. We discuss the design of the target [2]rotaxanes, synthesis and characterization of the axle, macrocycle precursors and macrocycles as well as preparation
  • [12], and drug delivery [13]. In spite of the important advancements in this field, the synthesis and characterization of these fascinating, complex molecules remains an important challenge and often requires intricate synthetic approaches. After the first templated synthesis of a [2]catenane
  • envisaged to combine active-metal template and clipping strategies and we report herein the synthesis and characterization of novel [2]rotaxanes by this new method that we name active-metal template clipping (Figure 1b). Thus, our approach involves the use of a metal ion connected to the dumbbell-shaped
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Published 20 Nov 2023

Selectivity control towards CO versus H2 for photo-driven CO2 reduction with a novel Co(II) catalyst

  • Lisa-Lou Gracia,
  • Philip Henkel,
  • Olaf Fuhr and
  • Claudia Bizzarri

Beilstein J. Org. Chem. 2023, 19, 1766–1775, doi:10.3762/bjoc.19.129

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  • maintaining high selectivity for carbon products. Results and Discussion Synthesis and characterization of the new Co(II)-based catalyst The novel cobalt(II) complex 1 was synthesized in dry methanol (MeOH) by mixing in a 2:1 ratio, the chelating diimine ligand, 1-benzyl-4-(quinolin-2-yl)-1H-1,2,3-triazole
  • detect, if the two polymorphs show different catalytic activity, as in the following investigations the amorphic powder was used. Spectroscopic and electrochemical characterization The Co(II) complex 1 was characterized by UV–vis absorption spectroscopy in N,N-dimethylacetamide (DMA), as it was the
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Published 17 Nov 2023

Effects of the aldehyde-derived ring substituent on the properties of two new bioinspired trimethoxybenzoylhydrazones: methyl vs nitro groups

  • Dayanne Martins,
  • Roberta Lamosa,
  • Talis Uelisson da Silva,
  • Carolina B. P. Ligiero,
  • Sérgio de Paula Machado,
  • Daphne S. Cukierman and
  • Nicolás A. Rey

Beilstein J. Org. Chem. 2023, 19, 1713–1727, doi:10.3762/bjoc.19.125

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  • errors of 2% (hdz-CH3) and 0% (hdz-NO2). In general, the structures calculated involving the IEFPCM formalism (water phase) displayed the best agreement with the experimental data. Regarding the vibrational characterization, infrared spectra were also calculated with both B3LYP/6-311G(d,p) – gas phase
  • and hdz-NO2 (Figure 5A and 5B, respectively). 13C NMR and 2D homonuclear (COSY) and heteronuclear (13C,1H-HSQC and HMBC) experiments were employed for the full characterization of these hydrazones, and the spectra can be seen in Supporting Information File 1, Figures S5–S12. Both compounds exhibit
  • maintained in DMSO-d6 solution. It is worth noting that the presence of the electron-withdrawing nitro substituent in hdz-NO2 makes the interaction stronger. An IR spectroscopy study, which was supported by computational calculations, as well as a complete NMR characterization of both compounds, align with
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Published 10 Nov 2023

A deep-red fluorophore based on naphthothiadiazole as emitter with hybridized local and charge transfer and ambipolar transporting properties for electroluminescent devices

  • Suangsiri Arunlimsawat,
  • Patteera Funchien,
  • Pongsakorn Chasing,
  • Atthapon Saenubol,
  • Taweesak Sudyoadsuk and
  • Vinich Promarak

Beilstein J. Org. Chem. 2023, 19, 1664–1676, doi:10.3762/bjoc.19.122

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  • Frontier Research Center, Vidyasirimedhi Institute of Science and Technology, Wangchan, Rayong 21210, Thailand 10.3762/bjoc.19.122 Abstract Herein, we report the synthesis and characterization of an efficient ambipolar charge-carrier-transporting deep-red fluorophore (TPECNz) based on a donor–acceptor
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Published 03 Nov 2023

A series of perylene diimide cathode interlayer materials for green solvent processing in conventional organic photovoltaics

  • Kathryn M. Wolfe,
  • Shahidul Alam,
  • Eva German,
  • Fahad N. Alduayji,
  • Maryam Alqurashi,
  • Frédéric Laquai and
  • Gregory C. Welch

Beilstein J. Org. Chem. 2023, 19, 1620–1629, doi:10.3762/bjoc.19.119

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  • NMR spectroscopy, mass spectrometry, and elemental analysis. See Supporting Information File 1 for full synthetic and characterization details. Optical properties Using UV–visible spectroscopy, the optical properties for PDIN-FB, PDIN-B, CN-PDIN-FB, and CN-PDIN-FB in both solution and film form were
  • no barriers between the active layer and the CIL interface, indicating efficient charge extractions. In addition, to further confirm the charge extraction and recombination, the PAIOS (platform for all-in-one characterization of solar cells) tool from Fluxim was used to measure transient photocurrent
  • investigation of the processes involved in the formation of the interfacial layer between the donor–acceptor and the charge transport layer. Nevertheless, based on all the optoelectrical characterization, proposed N-annulated perylene diimides-based CILs are suitable candidates for CILs that can be replaced
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Published 26 Oct 2023

Lewis acid-promoted direct synthesis of isoxazole derivatives

  • Dengxu Qiu,
  • Chenhui Jiang,
  • Pan Gao and
  • Yu Yuan

Beilstein J. Org. Chem. 2023, 19, 1562–1567, doi:10.3762/bjoc.19.113

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  • of reaction conditions for the synthesis of isoxazolesa. Supporting Information Supporting Information File 6: Characterization data and copies of spectra. Funding We are grateful for the financial support from the China Postdoctoral Science Foundation (2018T110533), the Natural Science Foundation
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Published 16 Oct 2023

Secondary metabolites of Diaporthe cameroonensis, isolated from the Cameroonian medicinal plant Trema guineensis

  • Bel Youssouf G. Mountessou,
  • Élodie Gisèle M. Anoumedem,
  • Blondelle M. Kemkuignou,
  • Yasmina Marin-Felix,
  • Frank Surup,
  • Marc Stadler and
  • Simeon F. Kouam

Beilstein J. Org. Chem. 2023, 19, 1555–1561, doi:10.3762/bjoc.19.112

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  • chemical constituents of another new species of Diaporthe. This genus contains many plant pathogenic, endophytic, and saprobic species [7]. So far, the investigations of chemical constituents of Diaporthe species, have led to the isolation and characterization of a myriad of potent natural products with
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Published 13 Oct 2023
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