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Search for "electrospray" in Full Text gives 183 result(s) in Beilstein Journal of Organic Chemistry.

Efficient synthesis of β’-amino-α,β-unsaturated ketones

  • Isabelle Abrunhosa-Thomas,
  • Aurélie Plas,
  • Nishanth Kandepedu,
  • Pierre Chalard and
  • Yves Troin

Beilstein J. Org. Chem. 2013, 9, 486–495, doi:10.3762/bjoc.9.52

Graphical Abstract
  • following abbreviations are used: singlet (s), doublet (d), doublet of doublets (dd), triplet (t), multiplet (m). High-resolution mass spectroscopy (HRMS) was carried out in electrospray mode and was performed by CRMP (Clermont-Ferrand, France). Monitoring of the reactions was performed by using silica-gel
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Published 06 Mar 2013

Multivalent display of the antimicrobial peptides BP100 and BP143

  • Imma Güell,
  • Rafael Ferre,
  • Kasper K. Sørensen,
  • Esther Badosa,
  • Iteng Ng-Choi,
  • Emilio Montesinos,
  • Eduard Bardají,
  • Lidia Feliu,
  • Knud J. Jensen and
  • Marta Planas

Beilstein J. Org. Chem. 2012, 8, 2106–2117, doi:10.3762/bjoc.8.237

Graphical Abstract
  • and 5 in 99% purity, and their structure was confirmed by electrospray-ionization mass spectrometry (ESIMS). With templates and peptide aldehydes in hand, the four-stranded structure 3 was prepared from Galp and peptide aldehyde 4 (Scheme 2). First, the reaction was conducted in a 1:1 solution of
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Published 03 Dec 2012

Preparation of mixed trialkyl alkylcarbonate derivatives of etidronic acid via an unusual route

  • Petri A. Turhanen,
  • Janne Weisell and
  • Jouko J. Vepsäläinen

Beilstein J. Org. Chem. 2012, 8, 2019–2024, doi:10.3762/bjoc.8.228

Graphical Abstract
  • [32]. Diastereomeric ratios for each of the compounds 3a–d were calculated from the 31P NMR spectrum. Mass spectra were recorded on a quadrupole time-of-flight mass spectrometer by using electrospray ionization (ESI) with positive-ionization mode for compounds 3a–d and 4 and negative for compound 2
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Published 20 Nov 2012

Automated three-component synthesis of a library of γ-lactams

  • Erik Fenster,
  • David Hill,
  • Oliver Reiser and
  • Jeffrey Aubé

Beilstein J. Org. Chem. 2012, 8, 1804–1813, doi:10.3762/bjoc.8.206

Graphical Abstract
  • TOF spectrometer for electrospray ionization (ESI). General procedure for the asymmetric organocatalyzed Michael addition of aldehyde 2{1} to maleimide 1{1} to produce 3{1,1} (Table 1) Propionaldehyde (2{1}) (31.2 μL, 0.433 mmol, 1.5 equiv) was added to a solution of N-phenylmaleimide (1{1}) (50.0 mg
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Published 19 Oct 2012

Synthesis of trifunctional cyclo-β-tripeptide templates

  • Frank Stein,
  • Tahir Mehmood,
  • Tilman Plass,
  • Javid H. Zaidi and
  • Ulf Diederichsen

Beilstein J. Org. Chem. 2012, 8, 1576–1583, doi:10.3762/bjoc.8.180

Graphical Abstract
  • % aq TFA), B (0.1% TFA in methanol) or C (0.1% TFA in MeCN) and water (0.1% TFA) within 30 minutes. Flow rates were taken as 1 mL/min for the analytical columns and 10 mL/min for preparative columns. All crude samples were dissolved in methanol or acetonitrile and filtered prior to use. Electrospray
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Published 19 Sep 2012

Studies on the substrate specificity of a GDP-mannose pyrophosphorylase from Salmonella enterica

  • Lu Zou,
  • Ruixiang Blake Zheng and
  • Todd L. Lowary

Beilstein J. Org. Chem. 2012, 8, 1219–1226, doi:10.3762/bjoc.8.136

Graphical Abstract
  • by high-resolution electrospray ionization mass spectrometry revealed an ion with m/z = 604.0691, which corresponds to the [M − H]− ion (calcd m/z = 604.0699) of GDP-Manp. Having established that the enzyme GDP-ManPP was active, we carried out the same incubations for 9–13, and in all cases the
  • . To confirm the identity of each GDP-Manp analogue, the product peaks were isolated and analysed by electrospray ionization mass spectrometry. For the reactions involving 9–12 a signal at m/z ≈ 618 was observed, as would be expected for the [M − H]− ion of the methylated GDP-Man derivatives (48–51
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Published 01 Aug 2012

Partial thioamide scan on the lipopeptaibiotic trichogin GA IV. Effects on folding and bioactivity

  • Marta De Zotti,
  • Barbara Biondi,
  • Cristina Peggion,
  • Matteo De Poli,
  • Haleh Fathi,
  • Simona Oancea,
  • Claudio Toniolo and
  • Fernando Formaggio

Beilstein J. Org. Chem. 2012, 8, 1161–1171, doi:10.3762/bjoc.8.129

Graphical Abstract
  • of 10−1 deg·cm2·g−1) were measured at 20 °C on a Perkin-Elmer PE241 polarimeter, with a 1 dm path length cell, at the D-wavelength of sodium (589 nm). The concentration of each compound (c) is given in mg/cL. Mass spectroscopy (electrospray ionization, ESIMS) was performed by using a PerSeptive
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Published 24 Jul 2012

Synthesis of 4” manipulated Lewis X trisaccharide analogues

  • Christopher J. Moore and
  • France-Isabelle Auzanneau

Beilstein J. Org. Chem. 2012, 8, 1134–1143, doi:10.3762/bjoc.8.126

Graphical Abstract
  • ), doublet of doublet of doublet (ddd), broad singlet (bs), broad triplet (bt), broad doublet of doublet (bdd) and multiplet (m). Mass spectra were obtained with electrospray ionization (ESI) on a high-resolution mass spectrometer. TLC were performed on precoated aluminum plates with Silica Gel 60 F254 and
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Published 23 Jul 2012

Synthesis and anion recognition properties of shape-persistent binaphthyl-containing chiral macrocyclic amides

  • Marco Caricato,
  • Nerea Jordana Leza,
  • Claudia Gargiulli,
  • Giuseppe Gattuso,
  • Daniele Dondi and
  • Dario Pasini

Beilstein J. Org. Chem. 2012, 8, 967–976, doi:10.3762/bjoc.8.109

Graphical Abstract
  • spectrophotometers. Mass spectra were recorded by using an electrospray ionization instrument. Optical rotations were measured on a polarimeter with a sodium lamp (λ = 589 nm) and are reported as follows: [α]Drt (c = g (100 mL solution)−1). CD spectroscopy was performed by using a spectropolarimeter; spectra were
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Published 28 Jun 2012

Intramolecular bridges formed by photoswitchable click amino acids

  • Christian Hoppmann,
  • Ronald Kühne and
  • Michael Beyermann

Beilstein J. Org. Chem. 2012, 8, 884–889, doi:10.3762/bjoc.8.100

Graphical Abstract
  • % trifluoroethanol (pH 7.5). The reaction mixture was exposed to λ = 365 (4 mW/cm2) for 45 min. LC–MS analysis was performed on an ACQUITY UPLC system equipped with a C18 column (3 μm, 2.1 × 30 mm) in combination with an electrospray time-of-flight (ESI–TOF) mass spectrometer (LCT Premier) from Waters. LC conditions
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Published 13 Jun 2012

An easily accessible sulfated saccharide mimetic inhibits in vitro human tumor cell adhesion and angiogenesis of vascular endothelial cells

  • Grazia Marano,
  • Claas Gronewold,
  • Martin Frank,
  • Anette Merling,
  • Christian Kliem,
  • Sandra Sauer,
  • Manfred Wiessler,
  • Eva Frei and
  • Reinhard Schwartz-Albiez

Beilstein J. Org. Chem. 2012, 8, 787–803, doi:10.3762/bjoc.8.89

Graphical Abstract
  • , Rheinstetten, Germany) with Me4Si (δ = 0) as the internal standard. Mass spectrometry electrospray ionization (ESI–MS) measurements were recorded on a Finnigan MAT TSQ 7000 instrument. All measurements were performed at the central spectroscopy unit of the DKFZ. Synthesis of 3,4-bis{[(β-D-galactopyranosyl)oxy
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Published 29 May 2012

Triterpenoid saponins from the roots of Acanthophyllum gypsophiloides Regel

  • Elena A. Khatuntseva,
  • Vladimir M. Men’shov,
  • Alexander S. Shashkov,
  • Yury E. Tsvetkov,
  • Rodion N. Stepanenko,
  • Raymonda Ya. Vlasenko,
  • Elvira E. Shults,
  • Genrikh A. Tolstikov,
  • Tatjana G. Tolstikova,
  • Dimitri S. Baev,
  • Vasiliy A. Kaledin,
  • Nelli A. Popova,
  • Valeriy P. Nikolin,
  • Pavel P. Laktionov,
  • Anna V. Cherepanova,
  • Tatiana V. Kulakovskaya,
  • Ekaterina V. Kulakovskaya and
  • Nikolay E. Nifantiev

Beilstein J. Org. Chem. 2012, 8, 763–775, doi:10.3762/bjoc.8.87

Graphical Abstract
  • Bruker micrоTOF II instrument by using electrospray ionization (ESI) [28]. The measurements were done in a positive-ion mode (interface capillary voltage: 4500 V) or in a negative-ion mode (3200 V); mass range from m/z 50–3000 Da; external or internal calibration was achieved with electrospray calibrant
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Published 23 May 2012

Enantioselective supramolecular devices in the gas phase. Resorcin[4]arene as a model system

  • Caterina Fraschetti,
  • Matthias C. Letzel,
  • Antonello Filippi,
  • Maurizio Speranza and
  • Jochen Mattay

Beilstein J. Org. Chem. 2012, 8, 539–550, doi:10.3762/bjoc.8.62

Graphical Abstract
  • , even in the gas phase. The most recent advances in this field include several gas-phase investigations: (i) The size and structure selectivity of tetraethyl and tetraphenyl resorcin[4]arenes in the recognition of mono, di-, and oligosaccharides by electrospray coupled with Fourier transform ion
  • the attention will be focussed on the most recent results obtained by our group with this particular kinetic method. Methodology The proton-bound [M∙H∙G]+ aggregates (M: chiral hosting resorcin[4]arene; G: guest biomolecule) were generated by electrospray ionization (ESI) of M/G methanolic mixtures
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Published 12 Apr 2012

Branching out at C-2 of septanosides. Synthesis of 2-deoxy-2-C-alkyl/aryl septanosides from a bromo-oxepine

  • Supriya Dey and
  • Narayanaswamy Jayaraman

Beilstein J. Org. Chem. 2012, 8, 522–527, doi:10.3762/bjoc.8.59

Graphical Abstract
  • Merck plates coated with silica gel GF254 (0.25 mm). Silica gel (230–400 mesh) was used for column chromatography. Optical rotations were recorded on a JASCO Model P-1020 polarimeter at the sodium D line at 24 °C. High-resolution mass spectra were obtained from a Q-TOF instrument by the electrospray
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Published 10 Apr 2012

Mutational analysis of a phenazine biosynthetic gene cluster in Streptomyces anulatus 9663

  • Orwah Saleh,
  • Katrin Flinspach,
  • Lucia Westrich,
  • Andreas Kulik,
  • Bertolt Gust,
  • Hans-Peter Fiedler and
  • Lutz Heide

Beilstein J. Org. Chem. 2012, 8, 501–513, doi:10.3762/bjoc.8.57

Graphical Abstract
  • B in 15 min (solvent A: water/formic acid (999:1); solvent B: acetonitrile/formic acid (999.4:0.6)). Detection was carried out at 230, 260, 280, 360, and 435 nm. Electrospray ionization (positive and negative ionization) in Ultra Scan mode with capillary voltage of 3.5 kV and drying gas temperature
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Published 04 Apr 2012

Self-assembly of Ru4 and Ru8 assemblies by coordination using organometallic Ru(II)2 precursors: Synthesis, characterization and properties

  • Sankarasekaran Shanmugaraju,
  • Dipak Samanta and
  • Partha Sarathi Mukherjee

Beilstein J. Org. Chem. 2012, 8, 313–322, doi:10.3762/bjoc.8.34

Graphical Abstract
  • salts in high yields and were characterized fully by multinuclear (1H, 13C and 19F) NMR, infrared (IR) and electrospray ionization mass spectrometry (ESIMS). In addition, the molecular structure of macrocycle 2a was established unequivocally by single-crystal X-ray diffraction analysis and adopts a
  • information about the exact composition and nuclearity of the final products. Electrospray ionization mass spectrometry (ESIMS) can be used as a soft-ionization method to elucidate the exact composition of the product [12]. The ESIMS analysis confirmed the formation of the rather unexpected [2 + 1] self
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Published 28 Feb 2012

Fluorescent hexaaryl- and hexa-heteroaryl[3]radialenes: Synthesis, structures, and properties

  • Antonio Avellaneda,
  • Courtney A. Hollis,
  • Xin He and
  • Christopher J. Sumby

Beilstein J. Org. Chem. 2012, 8, 71–80, doi:10.3762/bjoc.8.7

Graphical Abstract
  • elemental analyses. Low resolution electrospray ionisation mass spectra (ESIMS) were recorded on a Finnigan LCQ mass spectrometer. Samples were dissolved in HPLC grade methanol or acetonitrile with a concentration of 0.01 mg/cm3. High resolution electrospray ionisation mass spectroscopy (ESI-HRMS) was
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Published 11 Jan 2012

Valence isomerization of cyclohepta-1,3,5-triene and its heteroelement analogues

  • Helen Jansen,
  • J. Chris Slootweg and
  • Koop Lammertsma

Beilstein J. Org. Chem. 2011, 7, 1713–1721, doi:10.3762/bjoc.7.201

Graphical Abstract
  • + 2] cycloadditions of the in situ generated singlet phosphinidene 35 with olefins or acetylenes (Scheme 7) [5][6][7][8][9]. This approach has even lead to the detection of the transient phosphinidene species by employing electrospray ionization tandem mass spectrometry (ESIMS/MS); its gas-phase
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Published 21 Dec 2011

Impact of the level of complexity in self-sorting: Fabrication of a supramolecular scalene triangle

  • Kingsuk Mahata and
  • Michael Schmittel

Beilstein J. Org. Chem. 2011, 7, 1555–1561, doi:10.3762/bjoc.7.183

Graphical Abstract
  • characterised as received, by means of mass spectrometry, 1H NMR, diffusion-ordered spectroscopy (DOSY), differential pulse voltammetry (DPV) and elemental analysis. The electrospray ionisation mass spectrum (ESI-MS) of the reaction mixture suggests clean formation of the triangular species T = [Cu2Zn(5)(6)(7
  • and distilled prior to use. NMR measurements were carried out on a Bruker Avance 400 MHz spectrometer with the deuterated solvent as the lock and residual solvent as the internal reference. Electrospray ionisation mass spectra (ESI-MS) were recorded on a Thermo-Quest LCQ Deca. Differential pulse
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Published 22 Nov 2011

A new phenylethyl alkyl amide from the Ambrostoma quadriimpressum Motschulsky

  • Guolei Zhao,
  • Chao Yang,
  • Bing Li and
  • Wujiong Xia

Beilstein J. Org. Chem. 2011, 7, 1342–1346, doi:10.3762/bjoc.7.158

Graphical Abstract
  • ) ionization at 70 eV. 1H NMR spectra were obtained at 400 MHz on a Bruker AV-400 instrument. 13C NMR spectra were recorded at 100 MHz. High-resolution mass spectra were recorded on an Agilent 1200-6520 Q-TOF electrospray mass spectrometer. Isolation of (10R)-10-hydroxy-N-phenethyloctadecanamide (1
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Published 29 Sep 2011

A simple and convenient one-pot synthesis of substituted isoindolin-1-ones via lithiation, substitution and cyclization of N'-benzyl-N,N-dimethylureas

  • Keith Smith,
  • Gamal A. El-Hiti,
  • Amany S. Hegazy and
  • Benson Kariuki

Beilstein J. Org. Chem. 2011, 7, 1219–1227, doi:10.3762/bjoc.7.142

Graphical Abstract
  • impact (EI) at 70 eV and chemical ionization (CI) at 50 eV by the use of NH3 as ionization gas. Atmospheric pressure chemical ionization (APCI) mass spectra were measured on a Waters LCT Premier XE instrument. Electrospray (ES) analyses were performed on a ZQ4000 spectrometer in positive and negative
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Published 06 Sep 2011

Single enantiomer synthesis of α-(trifluoromethyl)-β-lactam

  • Václav Jurčík,
  • Alexandra M. Z. Slawin and
  • David O'Hagan

Beilstein J. Org. Chem. 2011, 7, 759–766, doi:10.3762/bjoc.7.86

Graphical Abstract
  • measured using a Perkin Elmer Model 341 polarimeter. Mass spectrometric (m/z) data was acquired by electrospray ionisation (ESI). High resolution mass analyses were recorded on a Micromass LCT TOF mass spectrometer using ES ionisation in positive ion mode. General aza-Michael procedure NaHCO3 (840 mg, 10.0
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Published 06 Jun 2011

Synthesis and self-assembly of 1-deoxyglucose derivatives as low molecular weight organogelators

  • Guijun Wang,
  • Hao Yang,
  • Sherwin Cheuk and
  • Sherman Coleman

Beilstein J. Org. Chem. 2011, 7, 234–242, doi:10.3762/bjoc.7.31

Graphical Abstract
  • using a 400 MHz Varian NMR spectrometer. High resolution mass spectrometry data were measured on the Q-Tof of the Mass Spectrometry lab at the University of Illinois after the low resolution masses were confirmed. The ionization technique used was ESI (electrospray ionization). Melting points were
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Published 21 Feb 2011

Surfactant catalyzed convenient and greener synthesis of tetrahydrobenzo[a]xanthene-11-ones at ambient temperature

  • Pravin V. Shinde,
  • Amol H. Kategaonkar,
  • Bapurao B. Shingate and
  • Murlidhar S. Shingare

Beilstein J. Org. Chem. 2011, 7, 53–58, doi:10.3762/bjoc.7.9

Graphical Abstract
  • cm−1. 1H NMR and 13C NMR spectra were recorded on an NMR spectrometer AC200 in CDCl3, chemical shifts (δ) are given in ppm relative to TMS. Mass spectra were taken on a Macro mass spectrometer (Waters) by the electrospray method (ES). Optical microscopy measurements: A drop of the turbid reaction
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Published 13 Jan 2011

Design and synthesis of a cyclitol-derived scaffold with axial pyridyl appendages and its encapsulation of the silver(I) cation

  • Pierre-Marc Léo,
  • Christophe Morin and
  • Christian Philouze

Beilstein J. Org. Chem. 2010, 6, 1022–1024, doi:10.3762/bjoc.6.115

Graphical Abstract
  • Information File 1). However, in the absence of characteristic signals for Ag(I)-complex (even at low temperature: −50 °C) NMR methods cannot be used for the determination of the complex stability constant. The electrospray mass spectrum (from the very solution contained in the NMR tube) revealed a 1:1
  • (ellipsoids are drawn at the 50% probability level and H atoms are omitted for clarity). Supporting Information Supporting Information features experimental procedures, 1H NMR and 13C NMR spectra; electrospray mass spectrum and the crystal structure of the Ag complex. Supporting Information File 158
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Published 29 Oct 2010
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