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Search for "environmentally sustainable" in Full Text gives 7 result(s) in Beilstein Journal of Organic Chemistry.

Recent advances in synthetic approaches for bioactive cinnamic acid derivatives

  • Betty A. Kustiana,
  • Galuh Widiyarti and
  • Teni Ernawati

Beilstein J. Org. Chem. 2025, 21, 1031–1086, doi:10.3762/bjoc.21.85

Graphical Abstract
  • examining these methodologies, the paper underscores their role in expanding the utility of cinnamic acid derivatives and addressing prevailing challenges. Keywords: biologically active; cinnamic acid derivatives; environmentally sustainable; synthetic methodologies; Review 1 Introduction Cinnamic acid is
  • applications in the pharmaceutical industry. In addition, innovative synthetic methodologies, including environmentally sustainable approaches [21][22][23], advanced catalytic systems [24][25][26], photocatalysis [27][28][29], and cutting-edge technologies, such as flow chemistry [30][31], have contributed
  • the past five years is presented, particularly emphasizing the active scaffolds of bioactive cinnamic acid derivatives. The review provides a strategic overview of alternative synthetic routes and highlights the latest innovations, including more efficient, highly selective, and environmentally
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Review
Published 28 May 2025

Multicomponent reactions driving the discovery and optimization of agents targeting central nervous system pathologies

  • Lucía Campos-Prieto,
  • Aitor García-Rey,
  • Eddy Sotelo and
  • Ana Mallo-Abreu

Beilstein J. Org. Chem. 2024, 20, 3151–3173, doi:10.3762/bjoc.20.261

Graphical Abstract
  • rapid generation of chemical libraries with high diversity in a time-efficient and environmentally sustainable manner. In this review, we focus on central nervous system (CNS) disorders, particularly Alzheimer's disease, Parkinson's disease, schizophrenia, depression, and epilepsy, where MCRs have
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Published 03 Dec 2024

Automated grindstone chemistry: a simple and facile way for PEG-assisted stoichiometry-controlled halogenation of phenols and anilines using N-halosuccinimides

  • Dharmendra Das,
  • Akhil A. Bhosle,
  • Amrita Chatterjee and
  • Mainak Banerjee

Beilstein J. Org. Chem. 2022, 18, 999–1008, doi:10.3762/bjoc.18.100

Graphical Abstract
  • reaction time, and mild reaction conditions are a few noticeable merits of this environmentally sustainable mechanochemical protocol. Keywords: automated grinding; chemoselectivity; mechanochemistry; N-bromosuccinimide; PEG-400; regioselectivity; stoichiometry-controlled halogenation; Introduction Aryl
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Published 09 Aug 2022

Nitroalkene reduction in deep eutectic solvents promoted by BH3NH3

  • Chiara Faverio,
  • Monica Fiorenza Boselli,
  • Patricia Camarero Gonzalez,
  • Alessandra Puglisi and
  • Maurizio Benaglia

Beilstein J. Org. Chem. 2021, 17, 1041–1047, doi:10.3762/bjoc.17.83

Graphical Abstract
  • safe as well as economically and environmentally sustainable alternative to the traditional organic solvents. Here, we report the combination of an atom-economic, very convenient and inexpensive reagent, such as BH3NH3, with bio-based eutectic mixtures as biorenewable solvents in the synthesis of
  • whole research community concerned with the concept of a circular economy [3]. In this context, deep eutectic solvents (DESs) have attracted an increasing attention as green, safe, economically and environmentally sustainable alternative to the traditional organic solvents [4]. They are combinations of
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Published 06 May 2021

Latest development in the synthesis of ursodeoxycholic acid (UDCA): a critical review

  • Fabio Tonin and
  • Isabel W. C. E. Arends

Beilstein J. Org. Chem. 2018, 14, 470–483, doi:10.3762/bjoc.14.33

Graphical Abstract
  • processing For an economically and environmentally sustainable process volumetric productivities have to be considered. In other words substrate loadings cannot be too low. While it does not represent a problem in chemical synthesis (UDCA, CDCA and CA are pretty soluble in alcohols like methanol and ethanol
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Published 20 Feb 2018

Mechanochemical synthesis of small organic molecules

  • Tapas Kumar Achar,
  • Anima Bose and
  • Prasenjit Mal

Beilstein J. Org. Chem. 2017, 13, 1907–1931, doi:10.3762/bjoc.13.186

Graphical Abstract
  • . Conclusion Significant progress has been made under the area of mechanochemistry during the last few decades owing to their improvement of environmentally sustainable and more selective processes. The major focus of this review is to cover the application of mechanochemistry in the synthesis of small organic
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Published 11 Sep 2017

Polydisperse methyl β-cyclodextrin–epichlorohydrin polymers: variable contact time 13C CP-MAS solid-state NMR characterization

  • Isabelle Mallard,
  • Davy Baudelet,
  • Franca Castiglione,
  • Monica Ferro,
  • Walter Panzeri,
  • Enzio Ragg and
  • Andrea Mele

Beilstein J. Org. Chem. 2015, 11, 2785–2794, doi:10.3762/bjoc.11.299

Graphical Abstract
  • , efficient and environmentally sustainable route to highly cross-linked, nanoporous polymers commonly referred to as cyclodextrin nanosponges. One of the most frequently used crosslinker for insoluble polymers is epichlorohydrin (EP). In this case, the reaction of β-CD with EP requires very strong alkaline
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Published 30 Dec 2015
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